Conserved Protein Domain Family
Mn_catalase
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pfam05067: Mn_catalase 
Manganese containing catalase
Catalases are important antioxidant metalloenzymes that catalyze disproportionation of hydrogen peroxide, forming dioxygen and water. Two families of catalases are known, one having a heme cofactor, and this family that is a structurally distinct family containing non-heme manganese.
Links
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Statistics
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PSSM-Id: 252986
Aligned: 6 rows
Threshold Bit Score: 373.515
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9KDZ2   1 MFkRIDKLLIDLPKPDHPDANAAAAVQELLGGRFGEMSTLNNYMYQSFNFRQKHKLRpfyELVASITAEEFGHVELVSNT 80  Bacillus halodurans
O34423   1 MF-YHIKELQYQAKPAHPDPVYAKKLQEVLGGQFGEISVMMQYLFQGFNCRADAKYK---DLLYDVGTEEIGHVEMLATM 76  Bacillus subtilis sub...
Q9KAU6   1 MF-YHVKHLQYHAKPERPDPVYAKKLQEILGGQFGEISVALQYLFQGWNTRGDGKYR---DLLMDTGTEELAHVEMLATM 76  Bacillus halodurans
P80878   1 MF-KHTKMLQHPAKPDRPDPLFAKKMQEILGGQFGEISVAMQYLFQGWNTRGNEKYK---DLLMDTATEELGHVEMIATM 76  Bacillus subtilis sub...
Q9I1T0   1 MF-VHDKRLQYTVRVAAPDPGLANLLLEQFGGPQGELAAAMRYFTQGLGECDPGR-K---DLLMDIATEELSHLEIIGSI 75  Pseudomonas aeruginosa
Q45538   1 MW-VYEKKLQYPVKVSTCNPTLAKYLIEQYGGADGELAAALRYLNQRYTIPDKVI-----GLLTDIGTEEFAHLEMIATM 74  Bacillus subtilis sub...

Q9KDZ2  81 INLMIEGTTFPGDPDITP----MQDAKDKRNTYH--FISTAQTSYPMDSMGASWRGDYVVNSGNLIFDLLHNYFLEIGAR 154 Bacillus halodurans
O34423  77 ISRLLDNAPADVQEDAYKsnpaIAAVMSGMNPQH--AIVSGLGAMASDSEGYPWNAKYIISSGNLLADFRANLNAEAQGR 154 Bacillus subtilis sub...
Q9KAU6  77 IARLLDGAPVGDQEAAAKnp-vIGAVLGGMNPQH--AIVSGLGAMPADSVGNRWTADYIIASGNLLADFRMNLTAESQGR 153 Bacillus halodurans
P80878  77 IARLLEDAPLDQQEKAAEdp-vIGSILGGMNPHH--AIVSGLGAMPESSTGVPWSGGYIVASGNLLADFRANLNAESQGR 153 Bacillus subtilis sub...
Q9I1T0  76 VGMLNKGAKGRLAEAVEEeaelYRSLTGGGNDSHitSLLYGGGPALVNSGGVPWSAAYIDTIGEPTADLRSNIAAEARAK 155 Pseudomonas aeruginosa
Q45538  75 VYKLTKDATPEQLREAGLgd---------------hYVNHDSALFYHNAAGVPFTASYIQAKGDPIADLYEDIAAEEKAR 139 Bacillus subtilis sub...

Q9KDZ2 155 THKMRVYEMTDHPVAREMIGYLLVRGGVHIIAYAKALEIATGVDlTKMLPVPnlsnrqfdYARKFEDQGVHRKLYTWSDM 234 Bacillus halodurans
O34423 155 LQVTRLYAMTDDPGVRDMLSFLIARDTYHQNMWYAAIKELEERErDIVVPTT--------FPRELEKQEVSYDLFNFSRG 226 Bacillus subtilis sub...
Q9KAU6 154 LQAVRLYEMTTDPGVRDMLSFLIARDRMHQNQWYAAICELEEKE-NIVVPST--------FPTHLEKQEVAHTFFNLSEG 224 Bacillus halodurans
P80878 154 LQVARLFEMTDDKGVKDMLSFLLARDTMHQNQWLAAIKELEAQE-GPVVPGT--------FPKALEKQEFSHQLINFSEG 224 Bacillus subtilis sub...
Q9I1T0 156 IVYERLINLTDDPGIKDALTFLMTRELAHQLSFEKALHSIQPNF-------P--------QGKLQGMPEFARRYLNMSRG 220 Pseudomonas aeruginosa
Q45538 140 ATYQWLIDISDDPDLNDSLRFLREREIVHSMRFREAVEILKEER------------------------------------ 183 Bacillus subtilis sub...

Q9KDZ2 235 DYRTISQIWKGEHPTEGGPLEVVKGTPEGAPIPDLeel----------peEFAPGISRDDfleiakrLKRNAGL 298 Bacillus halodurans
O34423 227 DESSQGRWAHGEAFDGRGEFRYIPAPIAFASAPHL---------------KPAPMWLHNT-------VPPMSKC 278 Bacillus subtilis subsp. su...
Q9KAU6 225 HESSTGRWASGPSMDSLSEFTYVAEPGAFGRIPRL---------------RPAPPYIHNTpivdkphVPPM--F 281 Bacillus halodurans
P80878 225 EVSAEQNWLNEKAPDG-EAFEYVKEAKTFGEKPEL---------------KPAPPFVHNT-------LPGR--E 273 Bacillus subtilis subsp. su...
Q9I1T0 221 EGDTRGSWNEGDGWEYVEAPQPALDGGDGTASVNLseteqevlqrmadrtRSDPMTDPLTgadlgagAAADKAP 294 Pseudomonas aeruginosa
Q45538 184 --------------------------------------------------------------------DKKKIF 189 Bacillus subtilis subsp. su...
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