Conserved Protein Domain Family
SOK

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pfam06136: SOK 
Protein SOSEKI, plant
This entry represents a group of plant proteins, including protein SOSEKI1-5 from Arabidopsis thaliana and Physcomitrium patens. SOK1-5 integrate apical-basal and radial organizmal axes to localize to polar cell edges and contain a DIX oligomerization domain that resembles that in the animal Dishevelled polarity regulator.
Statistics
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PSSM-Id: 461836
Aligned: 41 rows
Threshold Bit Score: 229.264
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003572509  55 VAVVYYLCR-SRH--LEHPHFIEVPLAAPdA-----GLYLRDVINRLNVLRGKGMAAMYSWSCKRSYKNGFVWHDISE-D 125
BAT09521      38 VAVVYYLCR-SRQggLEHPHLMEVEVGDG-EeqvhvQLRLRDVTRRLDALRGKGMAAMYSWSCKRSYRGGYVWHDLSHpD 115
KQK23177      46 VQIIYYLCR-NGQ--LEHPHFMELAQHPH-Q-----PLRLKDVMDRLTLLRGKGMPALFSWSCKRNYKNGYVWNDLSE-S 115
XP_002465712  43 VQIIYYLCR-NGQ--LEHPHFMELAQHPH-Q-----PLRLKDVMDRLTLLRGKGMPALFSWSCKRNYKNGYVWNDLSE-N 112
XP_006585287  34 VQVVYYLSR-NGL--LEHPHFMELTLLPN-Q-----PLRLKDVFDRLMALRGTGMPLQYSWSSKRNYKSGYVWYDLGL-K 103
XP_002533140  33 VQVVYYLSR-NGQ--LEHPHYMEVVHFTN-H-----HLRLKDVMDRLTVLRGKGMPSLYSWSCKRSYKNGYVWNDLAE-N 102
XP_002266219  31 VQVVYYLSR-NGQ--LEHPHYMEVTHLAN-Q-----QLRLKDVMERLTVLRGKGMPSLYSWSCKRSYKNGYVWNDLAE-N 100
XP_004970518  41 pAVVYYLSR-NGH--LEHPHFMEVALSSP-D-----GLYLRDVIDRLDALRGKGMARMYSWASKRSYRNGFVWHDLAD-D 110
XP_003567543  40 aAVVYYLSReDGQ--LDHPHFMEVPLSSPhR-----GLSLQDVLARLALLRGAAMAGAYSWSSKRGYRNGYVWHDLAA-D 111
BAJ84976      41 VPVVYYLSR-NGQ--LDHPHFMEVPVSSPqD-----GLCLRDVLDRLTVLRGAGMADAYSWSSKRSYKTGYVWHDLTA-D 111
XP_003572509 126 DLVLPAQGN----EYILKGS-----ELLDRSPP-DRl----QDGVGTAKVESlkhaqgEsPQSRGSQ------EGCSSSS 185
BAT09521     116 DLLLPTGPH----DYVLKASllhlhHLIDPPPR-----------HHPLITSTsssahhSlPPHAAAAahvslvSSSSTDA 180
KQK23177     116 DVIYPSDGV----EYVLKGS-----EIFPGCSSvDRlqhlrLTDRSP--------------------------------- 153
XP_002465712 113 DVIYPSDGV----EYVLKGS-----EIFPGCSS-DRfqhlrVTDRSP--------------------------------- 149
XP_006585287 104 DIIHPAEGG----EYVLKGS-----ELVEGCSErf-----nVRNKQQGIHQQa--------------------------- 142
XP_002533140 103 DIIYPSDGA----EYVLKGS-----ELVEGCS--ERlqqlqVTNNNRPLIQElnlhakGkQL------------------ 153
XP_002266219 101 DIIYPAEGA----EYVLKGS-----ELIEGCT--DKfqqlhVSNRVQHIPESn--------------------------- 142
XP_004970518 111 DYIHPVVGR----EYVLKGT-----ERLHPAVP-------------------------PaPLL--DA------AAASSSS 148
XP_003567543 112 DLVHPANDKdgteEYVLKGS-----KLLv-------------------------------PPRPRDA------SAGSSSS 149
BAJ84976     112 DPVHPASGA----EYVLKGS-----ELLRLL---------------------------PaPLYPRDA------SAGSSSS 149
XP_003572509 186 --SPSavikeassprpaqqpqqlaqsvfvpsssastnhedeqcrtthsGSSGNLSPEPAGTNApl----seESSPGPLEY 259
BAT09521     181 naNSVvvgddqct---------------------------sscrtqphSSSSSSSSSSSSASSsgsssshnNNSKEKEDE 233
KQK23177     154 ------------------------------------------------AK-TLALPHSHKQ-Yveryr------------ 171
XP_002465712 150 ------------------------------------------------TKPALALPHMSHKQYadsyr------------ 169
XP_006585287 143 -----------------------------------------------eANYNYSYDSRSKALGvcnkqqqqRESEELEEY 175
XP_002533140 154 ------------------------------------------------APSQQPKLQLEETHN---------TKFEFEDF 176
XP_002266219 143 -----------------------------------------------fHPKRIPLPRRSRHRE-------------PVEV 162
XP_004970518 149 sgSQEtpt--------------------------------------ssSSARWEAH---AHRKksa--garRAADGLGEY 185
XP_003567543 150 ssSSClv---------------------------------------qeQEPEGKTKTPMATGRagrr--knwSSFDLGEY 188
BAJ84976     150 ssSTSscq--------------------------------------agTDNHKKMPAAAVSRAhgrr--knwSSFDLGEY 189
XP_003572509 260 RVCK---------PIGAQDASTQTDDSERDVRG--KHARTARVCT-EDGTSDAEiqechderstqvsPKgpgiVRESPHM 327
BAT09521     234 KQVVgear-rpaaAVVVASAATQTDDDSSFTVTg---------------------------------------------- 266
KQK23177     172 ---------ddavEYPEDDEPAGYQPYHRRAAGaaARLARPDTKPgGVSARTTN-------------------RCHPVEL 223
XP_002465712 170 ---------ddavEDREDDE-LGYSYHHRRTASsgRLVAARADKP-AVSARATN-------------------RARPVEL 219
XP_006585287 176 Eeq---------eKEYEEGEKTSYTS----STTtpHSGCSRGVSTeEVVYEE---------------------------- 214
XP_002533140 177 Eedqe----qesqEEYEDEEKTSYT-----SSTtpHSRCSRGVSTdELEEPSKN---------------------PTTES 226
XP_002266219 163 ENMRdeehdyqeeEEEEDEEKTSYT-----SSNtsRSRCSRGVSTdEIEATQKN--------------------SNPTEL 217
XP_004970518 186 VVYKge--------eCAADAATQTEDGGRGHPR----------------------------------RAhaqaAAPQDEL 223
XP_003567543 189 RVAAavh--------pgADAATQTEDRRRRIPR----------------------------------------EPAATEL 220
BAJ84976     190 RVAAara-------gaGADAATQTDERRGRHGRg--------------------------------tEPslppQEPSTEL 230
XP_003572509 328 SLSEASP---------------GDRVETLE---SLIRAEAT----RRS-NYRV---LEEEQfYGPMGV---------KLK 372
BAT09521     267 ---SIAApsaqkqgaaggrgssSSSSRSLE---SLIMAEYS----GFRsMLEDdeeESAGGaDNSSRRrrscsmsiyRVK 336
KQK23177     224 PVEETSPpsstssdkppaaapaRQQASLCE----------E------------------------------------PNR 257
XP_002465712 220 PVEETSPpsstssdkppapattHQQQQTGRrasDLLQEPVE------------------------------------PSR 263
XP_006585287 215 ---EESKkkkkggggaggnnkkHLSGEKEKvkrRVVDGDGS------------------------------------GSS 255
XP_002533140 227 THHDSSPpppppp---------------psnkaHLITNPNNtpipKRYeDGDPiftES-------------------APS 272
XP_002266219 218 TLEDGSPpstsstvsdkanesnSNS--------------------KRFeDGDPvdsVFAEP----------------VLS 261
XP_004970518 224 SRAETSPptas------------tspETLE---ALIKADGR----VVAaISgs-----------------------gRAR 261
XP_003567543 221 GADEISPppss------------sspDTLE---TLINHDAR----LAAaSAAVaiaAPQRE-AAEAERvvgv-iaggRMR 279
BAJ84976     231 GADEISPppss------------sspDTLE---TLIKNDAR----VAAaSHAVaarREEEEdAGLALAqqgv-iaggRMR 290
XP_003572509 373 PANLLMQLITCG---SISVKDh--------RGFGLI-PTYR------PRFTQ------------VEFPSPVFSTP--MAL 420
BAT09521     337 PANLLMRLIACGcgsSIPI----------------------------PAAAAaa---------aKQQLQQVESLPlsPVL 379
KQK23177     258 TGSMLLQLIACG---SATA------------------GSAAkcgraePRRSC-------------GLVSRLSSRAgaDDD 303
XP_002465712 264 PASMLLQLIACGstaPVAAGG----------------GGGSgrcraePRRSC-------------GLVSRLSARGgaDED 314
XP_006585287 256 RYSGLLQLIACGg-----------------------gAGEYmkgkqgPRLSD---------------VGTKERDKkaLFW 297
XP_002533140 273 RNSVLLQLISCG---NLAVAKak-------------nNAAEslkhqqPKVTTvvikrsesnlhkGVLYKSAVKVA----E 332
XP_002266219 262 RNSVLLQLIACG---SMVSGKpk------------ngTSLKrssaniPVKNTnl--------hkGVLCKTAAKVA----E 314
XP_004970518 262 APSVLMQLISCG---SVSVRDaraspvmprARHHHNlHHHRhra-rpPRPPA-------------------SAAA----- 313
XP_003567543 280 ASAVLMQLISCG---SIPAA-----------------AKPKhqrsrlPRGRS-------------------------DLS 314
BAJ84976     291 ASSVLMQLISCG---SIPAAAkret--------gpggARYAaer-rlPRGRS---------------------------- 330
XP_003572509 421 RQLDIIPS-S--SR-TIGVRDQ-ESEYFSGRLVEM---NQQ----EESGKGDM-PTLKRSSSYDEDRVY 476
BAT09521     380 SPLSHLVNkQqlPH---------EQDRFSGGTIST---SNAnaagKLKVADDNaPPLVQSQiecsnapr 436
KQK23177     304 EEEEEEDAgGelSRrFGHMRVE-EKEYFSGSIVESg-gRGT---------PLPaSSLKRSNSYNEERGS 361
XP_002465712 315 EDEEEEAAgGelGRrFGHLAVE-NKEYFSGSIVEGaggRGT---------PLPaSSLKRSNSYNEERSC 373
XP_006585287 298 EEAETEMSeN--PRlLGNLQTE-EKEYFSGSLVDSikaHRE-----------GePVLNKSNSYNELRRS 352
XP_002533140 333 EDEIRYMSeN--PR-FGNLQAE-EKEYFSGSIVESmseNRV---------AADsAGLKRSNSYNEERST 388
XP_002266219 315 EDMINYISeN--PR-FGNLQSE-EKEYFSGSIVESmteDRV----------SIqPVLKKSSSYNEERSS 369
XP_004970518 314 -EVPTYR----------AKIVE-DKEYFSGSIIET---AKRssgdD-DTSQDLa-VLRRSSSYNADRVI 365
XP_003567543 315 SRVDASFSsGsgSSiAIGGMGM-DREYFSGSLVETttnNKS----LDRDGAGAgSELKRSSSYNADSvg 378
BAJ84976     331 -DLSSSTAaAdgFSgSIGVGASmEREYFSGSLVET---KKTasgdRAGHGGELg-ALKRSSSYNADRGR 394
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