Conserved Protein Domain Family
FUSC

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pfam04632: FUSC 
Fusaric acid resistance protein family
This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.
Statistics
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PSSM-Id: 428044
Aligned: 56 rows
Threshold Bit Score: 204.055
Created: 22-Mar-2022
Updated: 13-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q63MA6         39 WLHLAKTVAAALLAMGIAMLLDLSQPRIAMTTVFVLMQPMSGMVLAKSFYRVVGTGVGLVAALALGGLFAQQPELYMAGI 118 Burkholderia p...
Q0BQ71         28 FFYALRLALSGSLALYCAYFLQLQNPSSALVTTIIVASPMRGAILSKSLWRFLGTILGCVASIMAVALFVQSPLLYLSAF 107 Granulibacter ...
Q5FP45         25 AAFTARVFLSIGIALFLAFMIQLESPMSTVTTVLIVANPTVGALVSKSVWRMTGTVIGAALSTAVMAMFVQSAVLYFMVL 104 Gluconobacter ...
Q9I4A6         24 LGYVLRSIGAAALALGLGLYLQLDSPFSAASTVLLLINPVQGAVVGKGWWRAVGTLVGTLAAFVLTALFAQKMLLFVVAL 103 Pseudomonas ae...
WP_015958941   19 ASYTLRLTLSCAVLITLFMTLQIPFLAVALIVVFYVSQPNVLMIKLVSVVFFVTVTVALGGVLLIIKWTYDYPLIRLAAS 98  Enterobacteria...
jgi:Pden_0233  25 RATALRLTLAAMIAMVVATGLGLQNPWWAAMATWMIGQPPRGLLLERSVAQFAGTLLGAAAGVAIT--LAGNPSLQLAWL 102
jgi:Daci_5715  25 LRQHLRTAFAACLALLAAWQLGLEHPQWAAMATWAASQPLRGQLLEKSFFRVAGTVAGTAVGVGLVLLAQGNLLWLVLGL 104
jgi:Xaut_1306  17 LNFTLRTALAACCALLVAWLVGLEHPQWSAMTVWAAAQPVRGQLVEKSFFRALGTIIGSVAGIGLLFAAHGQQWAIVLGL 96 
Q5FUL5         42 VTFALRNTIAACLAVGIAFWMELDDPAWAAMTVWAVAQTSRGESQSKAKWRIVGTISGAIAAITIMAAAPQAPWMFFPMI 121 Gluconobacter ...
O05543         41 AGYALRTTCTSLLALGIALWMELGSPQWAALTVWMVAQGTRGRSLAKAKWHLFGMVVGVISGITLVAAIPQAPLMFILLL 120 Gluconobacter ...
Q63MA6        119 TLWVAGCIAAAV-R-----NRH-FRWYGYVLAGYTAALIGLPAVM-APNTLFLSALTRAAEVAVGIFCSGAVSALVL-P- 188 Burkholderia p...
Q0BQ71        108 AVWTGCCSYISN-L-----LRY-FRAYSAALAGYTIALIGFGDVLaHPDTIFSVALDRLSVVSLGIVCSALVTMLLQ-P- 178 Granulibacter ...
Q5FP45        105 SAFVGLACMTAT-C-----LRY-FRAYAAVLAGYTIIIVAVPAFA-HPENIFMSAMMRVSDVALGIVVTAAVFMVTS-Pr 175 Gluconobacter ...
Q9I4A6        104 GFWLGLCVGVMS-L-----VRH-FYATAAVVAGYTVCLALGPAMV-EPEAAFEHIVTRASAVIVGVCCLSLVTVLFS-R- 173 Pseudomonas ae...
WP_015958941   99 VALFFCALYLMR-------VLGkLGLAFFVVALAVIYAQTFPSMTsQSEILVRLLLWLWVAINTAILVTLLVNACFQ-Q- 169 Enterobacteria...
jgi:Pden_0233 103 ALWLALCCGLTN-A-----MRH-QRAYGAALAGLTASVVVTLTTG-TEIAPVSFAGARIADTLIGIGAALAVGFMLQ-P- 172
jgi:Daci_5715 105 AVWLGLCAGVGN-L-----QRS-FVAYGTMLSGYSAAMVALLDFA-HPDQVFALGWDRLFTALTGVFAALLVGWLFT-P- 174
jgi:Xaut_1306  97 AVWIGLCAGAGN-L-----LRG-FASYGAMLAGYSAAMVTLLHST-LAAGPFVVGIDRMLTVLLGVGVALAMGWMFTaPa 168
Q5FUL5        122 ALWIGLCSGFAT-F-----VSN-FRSYALVLAGYTCSIICMGAAS-NPDNVFMVAMSRGTYIVLGVLCEAFMGLIFA-Ts 192 Gluconobacter ...
O05543        121 AVGIGTFCMIGTfMpgpasMTN-YRIHGMRASGFTYAIVSLDGIA-DPHHIFAISMSRATYILLGIVLEASISGLFQ-Lg 197 Gluconobacter ...
Q63MA6        189 --LSSSDALMRTLSARHADFVAFAASTTAGAVERGEFe------------------RRFADFVDGIVGFEATRAFATFED 248 Burkholderia p...
Q0BQ71        179 --ATSENKLQADSMQSLRDLSELLTMVRDGASEEKIL-------------------DTRRRLLFRIASYDQAVEFGAAES 237 Granulibacter ...
Q5FP45        176 rrQGTMDALSGAFRETIRHALVFHEGLMNRSDAQDVPgsepvgtegafrslpqtiyDGRQRLLGQLARLGPAIEYAATDN 255 Gluconobacter ...
Q9I4A6        174 --RTVSGRVRQRLVSLCAATLALVAARHAGAADGELE-------------------RRRRTLAGEVYAVDDLLGVGRAES 232 Pseudomonas ae...
WP_015958941  170 --AFPGNQFKARLAGMLHEVARRLAAPDAEAPPTFG------------------------ETAAQFNQLQSLFAQASRAT 223 Enterobacteria...
jgi:Pden_0233 173 --RARAQTLSARSATVLADGLRLVGMALQQHQTDLV--------------------ARESAFLSTLAAISAGAEDAAAGS 230
jgi:Daci_5715 175 --KGSGIPGNAEVRQLFAQLLRDLAGSLQARGRASLGs------------------QEIAARLLAMAVIEEGLDPHAAGS 234
jgi:Xaut_1306 169 dpDDPARRVRRLTRRILDDLAAHLAGTLPPGRG------------------------EHQTLLSEMAAIEDALDGHAAGS 224
Q5FUL5        193 qeRHARAQLRQKLESALVLVTTTLCSLLGEERGALN---------------------AARRQFGTILTINDQIEFAEVEM 251 Gluconobacter ...
O05543        198 ltKRTRHQLASTFEDTLKPALTAIAGILVGKEGAMQ---------------------NVQAIFAQITTLGDQVEFAEVEL 256 Gluconobacter ...
Q63MA6        249 PYIRARSRRLARLNSEFMNACARLHAFHQLLRRLRANHAAEVLTa-----IAPHVDALSGvlyalradlarprars---- 319 Burkholderia p...
Q0BQ71        238 SEVARRANAFRQLFGLMTSVTASSMRIGERLQALSADPQTAEAAarlrriLSNLIQHIPD-------------------- 297 Granulibacter ...
Q5FP45        256 PDIHAGVRGYRLAVSRMTGLVASYHPYWRNLGVANPLSAPVHREir--dtLIQLLALTESagwie--------------- 318 Gluconobacter ...
Q9I4A6        233 RVLSAALPAIRGGLAALFSTLMEFRFAGETHWARCLAERGLAL---------PMADDLRLlggqlerge----------- 292 Pseudomonas ae...
WP_015958941  224 PEIAADPLAWRSRLAATLRCYQLAALLQADEADSDDRQQ-----------LSQAVLQLKNalsee--------------- 277 Enterobacteria...
jgi:Pden_0233 231 LRARRGLRPLNTIFASLLDLIVVARMIRKASESRSITRQAD---------LAALRAELERaadal--------------- 286
jgi:Daci_5715 235 QRSREAVHALRRLMNAQISALLWLRDAPSQE-------------------PPATFGEAQAlaaaq--------------- 280
jgi:Xaut_1306 225 LRSRATIRAIRRLLTAQVALLLWMRRPPRPACDGA---------------LVAAVRQATAafaad--------------- 274
Q5FUL5        252 GPHGHEGDHARAALAAVSALLSRGFGMAMRLQVLNHNHPAFTKT------ADEILAFLKQfpqrlpdqnavpalladlqh 325 Gluconobacter ...
O05543        257 GRHDHAGDHARAALADIAVLLARALDLATLMRLPLSQDDMFRQEae---aIRDMFLKLPArleetes------------- 320 Gluconobacter ...
Q63MA6        320 apspspspalvalsaYLAALPKRA-RASRRGLEtlap--agvLDFDTAIELLYRFVDEFLGYAETHASLALDSHV-LE-- 393 Burkholderia p...
Q0BQ71        298 ---------------NVQELRHLV-AASSHMHVel-----rhFANHTQCLKSLGLVNLLDDAARQLRMMARLADPrVQk- 355 Granulibacter ...
Q5FP45        319 -----------rpqgVLACLEEAL-GRLEVLEE-----------AATSPAVQASVDNVRDILLQLRETVLDLSSPrGP-- 373 Gluconobacter ...
Q9I4A6        293 -------ldfagaarRLASLRGRL-AAIRRGLPtd------qADACREGLFMERLDEQLDDLQAALRGFARLDGRaP--- 355 Pseudomonas ae...
WP_015958941  278 -----------pfdgAIPPLTLSG-RGVNRAVL-------------------QEMATTLQRLAQ--GEPVALPQGeVE-- 322 Enterobacteria...
jgi:Pden_0233 287 -----------qetgKLDPLPALG-MAERIAAD--------------HAELKAILGSFAAELREIAQSHQALAHPgRT-- 338
jgi:Daci_5715 281 -----------alreAAVALETRV-QLHEAAAAl--------VRAREAAVAWPGAADMLAPMGFALQAHLAATHDvALpp 340
jgi:Xaut_1306 275 -----------rpqdAEAHLRDDA-GRTGSDRM---------------------LHDALEGLAEAEATQPNGADGaRT-- 319
Q5FUL5        326 frdicrlyaaphresDVRSDFEPI-PGLEPFDQtdeg-qemqEDRLDERILFVSLGELLGDLEQAIKEYEASTHRiKGd- 402 Gluconobacter ...
O05543        321 ---------masilaDLLTLRRQCrQKVVSDFStaqpddaarEAVLRHGMLQQALVELIDALRMALTQFEASRHPgS--- 388 Gluconobacter ...
Q63MA6        394 ---RSVTR--YAVKTNRYFVGFTFLRTLVAMGAMSAFWIASEWSSGSLAVIGTAIACALSSTAPRASRFVAQMAAGAALA 468 Burkholderia p...
Q0BQ71        356 ---IRRVR--LPLWRDHVTALRSGLRAFLAAELLGLFWIYTEWPSGGSAIVMTAIIVALAATGDNPSGMMKAFLQGTLIA 430 Granulibacter ...
Q5FP45        374 ---HVRVR--VLPYLEWMSAIYNGLRGMLIAFLACMIWYITYFPTGPMMIMYVVAASSLLSTAPSAARASLPMAIGTALS 448 Gluconobacter ...
Q9I4A6        356 ---ADVRP--AAFHRHYREALRNGARAWLAMLVGGALWFLSGWDQGPTLLAVLGPYCTLLAASPFPAEGTRNFIRGTLYA 430 Pseudomonas ae...
WP_015958941  323 ---KAPLL--APDAWRNPAYLHFALKTLLATLICYVFYTAADWQGLHTIMLSCVIVA--QPGLGATMQKTWLRIGGALLA 395 Enterobacteria...
jgi:Pden_0233 339 ---VCAAR--LHPQPDLTGLRRAMARGFLAIAASALVWTVTGWEAGRFLVLGASIFTVLFATLDQPLPLVRQGLIGGAVA 413
jgi:Daci_5715 341 ghrARQWP--VVLHSDWLGARRAMLRASAAIAIVGLLWVVTGWSGGAYMLLGMSIMLTVFSGFENPSATMRHVTLGQAMG 418
jgi:Xaut_1306 320 ---GAHDG--VVLHRDLIGAREALIRATVTLLAVGAAWLATGWEAGAFMLLGAAIMTSIFSTADNPAQTLKQVMMGQMLG 394
Q5FUL5        403 ---HFHFQ--LETHRDTREAVHNGLRGACAVLITAYIYEVTAWPNGPGFIAITTLVCGLFATKENPVLGTTEFLKGAVAA 477 Gluconobacter ...
O05543        389 ---HDHFHspIRSYRDWQQAITNSLRSSVTVFGAGLIWICTAWPSGLTFIMFVCIVCSLFSTLERPALATQAFLRGACCA 465 Gluconobacter ...
Q63MA6        469 TLTGYLYVCRVYPNIDG-FPLLCAALAPVLAAGAYLATRPGKSG-YGIGFVVFFCLLAGPDNVIVYAPDVLINNGLALVV 546 Burkholderia p...
Q0BQ71        431 SVLSFVLVYGILVHMDG-FPLLLMAYMPIVILCGYMQASGRNPA-LAMSIMLFYAVLSPIANPIHYNLTGFLNSVFSSII 508 Granulibacter ...
Q5FP45        449 VPACWLCHIAAIPRVDG-YPMLWLSVCACMLPGVWLQFHPRYGV-GAFGYTVFLAMQLMITNSMVPDDITLINTWLAILM 526 Gluconobacter ...
Q9I4A6        431 IPAALLCKFLLLPLING-FPLLLLCLAFFWSFGIQATTVPRRAL-QGIAYLIAFNTLVATGNLARFDFGDFANQSCAWVL 508 Pseudomonas ae...
WP_015958941  396 SLLALLLIVFVQPWTDSlTGLLAMSLPVLALAAWIAAGSERIAY-AGIQIGFTFALAFLSWFAPLTNLTELRDRVLGILL 474 Enterobacteria...
jgi:Pden_0233 414 ALAAVAWRLDVVPFAE--VPWFSLLLALPLFCAASLLQASRATIfAGLTFNMFFAVLARPVDMLPSSSQVVVASAAMLIL 491
jgi:Daci_5715 419 VLVALACQWLVWPFAGS-QAGLVWLMLPFVYVGALLFSHQRTAL-SGYDCNMVLLLLLQPHYPQTASFGHALALGLAVVS 496
jgi:Xaut_1306 395 AAGALTCRWLVWPHADS-AFGLVLAMMPFILLGAFIQAHRRTAGpIGFDYSMVVLLMLQPAWPLAGTLAHSLMLAGAVVL 473
Q5FUL5        478 CIVAWILVFVLMPKVTT-FETLALFLGPAMFLGGLAKGNPATAG-GSAAYGLLLPAMLGLENHHVMNEIAFYNGNMATVL 555 Gluconobacter ...
O05543        466 VVAAGILNLALMGKSTT-FEMLGMWSGLAMMIGGLAFAYPPLTL-PAVSYNLFLPILIGPSNQAKTDEIVYFNTALPLVL 543 Gluconobacter ...
Q63MA6        547 SMLAASIAFAVVFPAEMPWLTGRIARDLRRQIALACDGPLQG---LDQ--RFQSSSHDLMSQLRNLLM-----KRSRRHR 616 Burkholderia p...
Q0BQ71        509 GALAANIAFMILVPPSFEMSIRLATLSLWRGVSDAARKKMPA---SNL--TWEYPQYQKLMRISARLP-----PAGPERR 578 Granulibacter ...
Q5FP45        527 GCALLVLVFRVIMPADQRLYASRLVISLGRSLQSLSARPAAK---VPSwmVWEGTQIQKVSILLMRLSl---vASPIDRQ 600 Gluconobacter ...
Q9I4A6        509 ALCISLLVYRLL-PKDLERHSASLLDHLRRETLALLRRRAGF---DAH--AWQARQQHRIAQLGALHG-----MEHPRSA 577 Pseudomonas ae...
WP_015958941  475 GVLVSSIVHLYLWPDSEAPQLKTRLAALYRRLADCLAAPKEAvplA----PLLVAFTDSEALIHRVRAeplgtYAHPWPQ 550 Enterobacteria...
jgi:Pden_0233 492 GVAISDFFYRWVLPMDVDRRRRHIEASIRREIVSVSLRAGTP---------WAERHLSRLRHLVLEMV-----MRARADT 557
jgi:Daci_5715 497 GPLAGWAAYRFILPVTLQGRLQSLRSMMVHELQ-DMAATPGH---ARDgrIWRARLYHRLLRLVRMSEq----AGGQLGA 568
jgi:Xaut_1306 474 GPAVGLMAFLLIFPVDGHRRQQTLVTMMVHDLQSMAAHPGAA---RQRa-VWRARLYHRVLRLARWAD-----KTGGSRE 544
Q5FUL5        556 AVAVSVIVFRSVLPFSSDAERFRLRRIMLGELQHLAHPGFTP---RIS--VWIGRNTDRFARLIRHAGp----TPAPLIE 626 Gluconobacter ...
O05543        544 GLLYASWMYRVFLPYDPAHQRWTMREHILRDLHRIADGRAQE---TVD--SVVSRNVDRFVRLMTNSGs----TPSPVIQ 614 Gluconobacter ...
Q63MA6        617 DALRWMLATLEIGHAVIDLRREMQAFtaaqpaQALRWRALIDAVREALPrlfetpdahrlaralKSVNLAIRAVRHTQHL 696 Burkholderia p...
Q0BQ71        579 RIGRGSAALVLTGREIFKIRHAIEHGi-----VPVSARPAVQRLLAVLR---------------RQPQRAAEFADHACRE 638 Granulibacter ...
Q5FP45        601 GYVDGAFAALSLGRLLIRLRQAVEPAg-----LNAREREALDVALASFRtl------------rRDPVGTAASLMAAAGL 663 Gluconobacter ...
Q9I4A6        578 LALRLGFVSLQLGRESRRLWRALAGLd-----PAAAEARWIERALRAIAvr------------hRDPPLAARHARRAGAR 640 Pseudomonas ae...
WP_015958941  551 AKGWPMRATLAQAEEIARLSE-----------GYRLNAAPGDPTLARCAeq-----------lrRYAERIEQEATAPGEQ 608 Enterobacteria...
jgi:Pden_0233 558 EVVGNAVAALSLGHIAMRLGQIAHQEt-----PAADGGAITKDCLRRLAnp------------iSDPAACGREILKANQA 620
jgi:Daci_5715 569 QAAECGLAALHVGRAIQALHQLSGEAa-----LGDGTARAVRAALLRLQrl------------qQAPGQCPPLLRALAQR 631
jgi:Xaut_1306 545 QAMEGGFAVLLLGSAILHMDEALNQSd-----PAPGTARRLNAALARLRhv------------gSDPERAARALGVAATR 607
Q5FUL5        627 ACILGTLATLTLGLNVIRLRALLDREy-----LPESARRPILLVLHYVEqst---------krhDKAARIAEAAVRRLRV 692 Gluconobacter ...
O05543        615 AYLTGILSGMRVMLNLLRLQAIRRDTr-----LNPEAGQALALIMGRMShfsgryh-ghygrtlRATKLAILRLRTCERN 688 Gluconobacter ...
Q63MA6        697 WYAVPDERRr---MQRIVSCLHFIRSALIDQDAPF 728 Burkholderia pseudomallei
Q0BQ71        639 VVAAGVHDPq---LLRTAASLAELHLLLLEGGRQV 670 Granulibacter bethesdensis CGDNIH1
Q5FP45        664 IGAGEASGMeglyRVRLVSCLEQSAHIIDSIPGFF 698 Gluconobacter oxydans
Q9I4A6        641 LAAAGE--------WRLAAILTDLAWLLRAYSqsv 667 Pseudomonas aeruginosa
WP_015958941  609 LTADLTNPFgp-aLAAALAALPDWGPTPIATEQQA 642 Enterobacteriaceae
jgi:Pden_0233 621 VPAETATSA--------VRLAHLMARELVDHPKVF 647
jgi:Daci_5715 632 VAERHPDQA---------RQLRHAAHEIAQHEAFF 657
jgi:Xaut_1306 608 LAADGTGDG---------DLLREAAAELSQRAAFI 633
Q5FUL5        693 LDAQETDLVtrleLTRAITYLVVIAYTMRTNEDFL 727 Gluconobacter oxydans
O05543        689 EDRPRERFV----LIAALTSLDVIATELDTNRIFF 719 Gluconobacter oxydans 621H
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