Conserved Protein Domain Family
MMtag

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pfam10159: MMtag 
Multiple myeloma tumor-associated
This is a glycine-rich domain that is the most highly conserved region of a family of proteins that in vertebrates are associated with tumours in multiple myelomas. The region may contain nuclear localization signals, so it might act as a signal molecule in the nucleus.
Statistics
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PSSM-Id: 431097
Aligned: 65 rows
Threshold Bit Score: 75.6889
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002141076  14 GVRGGY---ERFNWTSLKSIPTSerEHYLGQSMQVGIatrgGKFYRH---DWYYKGGDIRRTIDrstisdkmgsnknvat 87 
EKG21064      11 GSRGSQaigDNVDVEGIRSSNHR--ENYLGHSILAPV----GRSERRrdqLFWARDKPSANVDEd--------------- 69 
EOD45595      11 gsrgsaaigdNVDVENIRNSNHR--ENYLGHSILAPV----GRSERRrdqLFWARNNAAIDVEDe--------------- 69 
XP_002175474  10 GTRGGQ---GLFDWENVKKDHQR--ENYLGQSLYAQT----GRWAKGkdlEWWSKGKTTIAESSarps----------er 70 
O14256         7 GTRGGQ---AQFQWEEVRNDKQK--GRYLGQSIYAAS----GRWAEGkdlEWWSKGRTTQSAINsens----------dk 67  Schizosaccharom...
XP_013023552  10 GTRGGQ---GEFQWDQVKSDKQK--GNYLGQSIYAAS----GRWAQGrdlEWWSKGRTTQAEPNsnn------------e 68 
Q23R95        11 GTRGGR---DQFKWDDVRQMSHKdrEQYLGQSAMMGFldkgGKWRKK---DWYTKNVDDEDEEDe--------------- 69  Tetrahymena the...
EGR27065      11 GVRGGR---DQFKWDNVRQMTHKdrEQYLGQTLKIGFldkgGKWRKK---DWYLKSKG---------------------- 62 
Q4MZB0        12 GTRGGR---EQFKWEDLKSHDLKdrEHYLGHSVKVGLlerkNKFYKH---DWYLKKDSKSHTDT---------------- 69  Theileria parva
XP_001611498  11 GTRGGR---EQFKWEDIKNCDNKerEHYLGHSVKIGTvkykNHFYKH---DWYLKNDNKATEG----------------- 67 
XP_002141076  88 sNIKDEKLLVKQYEDQYISKLLG 110
EKG21064      70 -ELRQEFKEAQIRERRALNEALG 91 
EOD45595      70 -EIKQERKEAQIRERRALNEHLG 91 
XP_002175474  71 dEAKREIEEIKRREQELLSQMIG 93 
O14256        68 eKYKKEILEIKEREQRMLAEALG 90  Schizosaccharomyces pombe 972h-
XP_013023552  69 eAYKKEILEVKYKEQVMLAETLG 91 
Q23R95        70 -KIKQERQKIIENDQKRIRIALG 91  Tetrahymena thermophila SB210
EGR27065      63 -QQQNEIDEIQSQDQKRIRIALG 84 
Q4MZB0        70 -LEEDEAELTRLYEQEIMQEML- 90  Theileria parva
XP_001611498  68 -DPNEELQLIKLYEDELMLEMLG 89 
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