6M2M


Conserved Protein Domain Family
CHZ

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pfam09649: CHZ 
Histone chaperone domain CHZ
This domain is highly conserved from yeasts to humans and is part of the chaperone protein HIRIP3 in vertebrates which interacts with the H3.3 chaperone HIRA, implicated in histone replacement during transcription. N- and C- termini of Chz family members are relatively divergent but do contain similar acidic stretches rich in Glu/Asp residues, characteriztic of all histone chaperones.
Statistics
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PSSM-Id: 462846
Aligned: 48 rows
Threshold Bit Score: 35.6952
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6M2M_M        24 ERAKELEGIDMSNIITSSRR-RSTSNFIPLPTPK 56 
EPS27438      56 EADDSLEPISESNIISSGRRtRGRNINWEEVRNK 89 
EHY54456      53 EEDEDMEEIDPSNIVQG--RtRRKQIDWAEAEQK 84 
EEF46081     409 ERAKELEGIDMSNIVSSSRR-RSATSYVPPPKPK 441
Q2R2Z3       390 ERAKELEGIDMSNIITSSRR-RSTSNFIPLPTPK 422 Japanese rice
CBI19035     413 ERAKELEGIDTSNIVLSSRR-RSTRSFVAPPKPK 445
XP_016292549  68 EDDEELAEIDTSNIVWTGRR-RNAPLDYSSEEAL 100
XP_009268088  61 VVDDDLEEIDPSAIVDSGSRrTRSNVDYSSADAR 94 
XP_002473236  58 mEEDDLGEIDPSAIITGTRRtRGVRVDYSSAAAL 91 
A8N7N4        63 EEEETFEEIDPSAILPTGRRtRGVRVDYTSKEAL 96  Coprinopsis cinerea okayama7#130
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