Conserved Protein Domain Family
murE

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PRK00139: murE 
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Links
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Statistics
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PSSM-Id: 234660
Aligned: 607 rows
Threshold Bit Score: 328.244
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
283782955  18 GLLREMIQygkAedtntangantkektidsthsrneiwslnpyyfpnidadEYFTNATYDTRDIKSGTLLFIKGN-F--K 94 
166154480   1 MHLDQLLR---Nipakiy----------------------------gkvesIPVRNLTRDSRCVGVGDIFIARQGqFcnG 49 
166155355   1 MHLDQLLR---Nipakiy----------------------------gkvesIPVRNLTRDSRCVGVGDIFIARQGqFcnG 49 
237802692   1 MHLDQLLQ---Nipakiy----------------------------gkvesIPVRNLTRDSRCVGVGDIFIARQGqFcnG 49 
62184995    1 MNLKELLH---Ntkakiy----------------------------gkissVEVRNLTRDSRNVGVGDIFIAKQGkHcdG 49 
89898439    1 MNLKELLH---Nididakv--------------------------ygkispIEVRNLTKDSRNIGFGDIFIANKGkRcdG 51 
29840139    1 MNLKELLN---Nieakiy----------------------------gkvspIEVRNLTKDSRNVGFGDIFIANKGkQfdG 49 
16752621    1 MDLKELLH---Gvqakiy----------------------------gkvrpLEVRNLTRDSRCVSVGDIFIAHKGqRydG 49 
15618333    1 MDLKELLH---Gvqakiy----------------------------gkvrpLEVRNLTRDSRCVSVGDIFIAHKGqRydG 49 
15835951    1 MDLKELLH---Gvqakiy----------------------------gkvrpLEVRNLTRDSRCVSVGDIFIAHKGqRydG 49 
283782955  95 SEYLLDADNKGLAAYVAEqsyaqyTKAVGLIVTDAKKAMSVLAAAFFGNPQEKLTIVGITGTKGKTTTAYFTHAILNSHS 174
166154480  50 NDYSSQAVANGAIAVLSSlyn-pfLSVVQIIAEDPIALEASLAARFYNNPSKHLDVIGITGTNGKTTVSCLVRELMERSG 128
166155355  50 NDYSSQAVANGAIAVLSSlyn-pfLSVVQIIAEDPIALEASLAARFYNNPSKHLDVIGITGTNGKTTVSCLVRELMERSG 128
237802692  50 NDYSSQAVANGAIAVLSSlyn-pfLSVVQIIAEDPIALEASLAARFYNNPSRHLDVIGITGTNGKTTVSCLVRELMERSG 128
62184995   50 NDFSHLAVENGAIAVASSiyn-pfLPVVQIISSDLPRLEADLAAKYYGHPSQKLCVVGITGTNGKTTVSHLIKLLFDACD 128
89898439   52 NDFASLAVENGAIAVVSSiyn-pfLSVVQIISPNLSLLEAQLAAKYYNYPSRKLCVVGITGTNGKTTVSHLIKFLFDACD 130
29840139   50 NDFSPLAIENGAIAIASSiyn-pfLSVVQIVSSNLPQLEAELSAKYYNYPSKKLCIVGVTGTNGKTTVSHLIKTLFDGCN 128
16752621   50 NDFAVDALANGAIAIASSlyn-pfLSVVQIITPNLEELEAELSAKYYEYPSSKLHTIGVTGTNGKTTVTCLIKALLDSYQ 128
15618333   50 NDFAVDALANGAIAIASSlyn-pfLSVVQIITPNLEELEAELSAKYYEYPSSKLHTIGVTGTNGKTTVTCLIKALLDSYQ 128
15835951   50 NDFAVDALANGAIAIASSlyn-pfLSVVQIITPNLEELEAELSAKYYEYPSSKLHTIGVTGTNGKTTVTCLIKALLDSYQ 128
283782955 175 hGKAALFSSVDNCVDGknyvesnLTTPESFDAFKMMREAVDNDMKYLVMEVSSQAYKVNRVYGLKFDVAAFLNISPDHIS 254
166154480 129 -IRTGLIGTIEHILGEnri-vdsFTTPDAILLQKYFAEMVKQNLSAAVMEVSSIGMALGRVRETEFLAGVLTNITSDHLD 206
166155355 129 -IRTGLIGTIEHILGEnri-vdsFTTPDAILLQKYFAEMVKQNLSAAVMEVSSIGMALGRVRETEFLAGVLTNITSDHLD 206
237802692 129 -RRTGLIGTIEHILGEnri-idsFTTPDAILLQKYFAEMVKQNLSAAVMEVSSIGMALGRVRETEFLAGVLTNIISDHLD 206
62184995  129 -KPAGLIGTIEHILGNsri-qdgYTTPESCLLQKYLAKMVKSHLSAAVMEVSSIGLAVNRLANVDFDVGVLTNLTLDHLD 206
89898439  131 -KPSGLIGTIEHILGNnri-qdgFTTPESCLLQKYLAEMVKSNLTAAVIETSSIGLVLDRLANVEFDVGVLTNVTLDHLD 208
29840139  129 -KPSGLIGTIEHVLGNnri-qdgYTTPESCLLQKYLAEMVKNRLTSAVMEVSSVGLVLERLAEVDFDVGVLTNITLDHLD 206
16752621  129 -KPSGLLGTIEHILGEgvi-kdgFTTPTPALLQKYLATMVRQNRDAVVMEVSSIGLASGRVAYTNFDTAVLTNITLDHLD 206
15618333  129 -KPSGLLGTIEHILGEgvi-kdgFTTPTPALLQKYLATMVRQNRDAVVMEVSSIGLASGRVAYTNFDTAVLTNITLDHLD 206
15835951  129 -KPSGLLGTIEHILGEgvi-kdgFTTPTPALLQKYLATMVRQNRDAVVMEVSSIGLASGRVAYTNFDTAVLTNITLDHLD 206
283782955 255 piEHPTFEDYLYCKRQIIANTK---RLVLNSDTDHadlllqdaerNNVLVTtfarikkdeiegdacENNNFDDLdddcin 331
166154480 207 --FHGSLEEYIAAKKQFFASLPekgIAVVNLDCEY----------APSFLN---------------GSQARAVSyai--- 256
166155355 207 --FHGSLEEYIAAKKQFFASLPekgIAVVNLDCEY----------APSFLN---------------GSQARAVSyai--- 256
237802692 207 --FHGSLEEYIAAKKQFFASLPekgIAVVNLDCEY----------APSFLN---------------GSQARAVSyai--- 256
62184995  207 --FHSSFEEYKQAKLKLFSMLPssgLAVVNNDLCD----------AAQFIE---------------ATQAQPITygi--- 256
89898439  209 --FHDSFEEYIKAKLQLFAQLSdsgLAVVNNDLPQ----------AKQFLE---------------ATRAVPVTygi--- 258
29840139  207 --FHGSFEEYINAKLKLFSKLPatgLAVVNGDLSY----------ASRFLE---------------MTQAQPITygi--- 256
16752621  207 --FHGTFETYVAAKAKLFSLVPpsgMVVINTDSPY----------ASQCIE---------------SAKAPVITygi--- 256
15618333  207 --FHGTFETYVAAKAKLFSLVPpsgMVVINTDSPY----------ASQCIE---------------SAKAPVITygi--- 256
15835951  207 --FHGTFETYVAAKAKLFSLVPpsgMVVINTDSPY----------ASQCIE---------------SAKAPVITygi--- 256
283782955 332 ycapandddyteLlTPDYIAMPVENSESHCIAMRdssedddyedndyeedvhycpidEFALSIAGDFNYENALAAIAIAG 411
166154480 257 ----------hqEaDYRADRLKLYSSGSSYDIWYqgk------------------vfPCETSLIGEHNVYNVLASLAVVH 308
166155355 257 ----------hqEaDYRADRLKLYSSGSSYDIWYqgk------------------vfPCETSLIGEHNVYNVLASLAVVH 308
237802692 257 ----------hqEaDYRADRLKLYSSGSSYDIWYqgq------------------vfPCETSLIGEHNVYNVLASLAVVH 308
62184995  257 ----------eqHaDYQASHVRFSPFGTDFDLLYkge------------------tfACYSPLIGQHNIYNVLAAIAVTH 308
89898439  259 ----------eqLaDYRASNLRFSPFGADFDLIHkge------------------ifPCHSPLIGQYNVYNVLAAIAVTH 310
29840139  257 ----------ecPaDYRAMHLRSSPFGTDFDLVYrge------------------slPCRLPLIGKHNVYNILAAIAVAH 308
16752621  257 ----------esAaDYRATDIQLSSSGTKYTLVYgdq------------------kiACSSSFIGKYNVYNLLAAISTVH 308
15618333  257 ----------esAaDYRATDIQLSSSGTKYTLVYgdq------------------kiACSSSFIGKYNVYNLLAAISTVH 308
15835951  257 ----------esAaDYRATDIQLSSSGTKYTLVYgdq------------------kiACSSSFIGKYNVYNLLAAISTVH 308
283782955 412 E-LGINQDTDlhaLHAIENVK-ISGRMEVFKdthsnMIAVVDYAHNYISTKSVLDFVE----E-RygkfnpRITLITGST 484
166154480 309 QfLGGDFADL---VRDVRFLSaPKGRLDPILlg--pFPVYIDYAHTPDALDNVCRILLqllpKyG------RLIIVFGCG 377
166155355 309 QfLGGDFADL---VRDVRFLSaPKGRLDPILlg--pFPVYIDYAHTPDALDNVCRILLqllpKyG------RLIIVFGCG 377
237802692 309 QfLGRDFADL---VRDVRFLSaPKGRLDPILlg--pFPVYIDYAHTPDALDNVCRILLqllpKdG------RLIIVFGCG 377
62184995  309 QrLRCDLPHL---ISVIANVGaPRGRLEPIFsg--pCPIYIDYAHTPDALDNVCQTLQallpQdG------RLIVVFGCG 377
89898439  311 QrLNCDLQQL---VSLVASVKsPRGRLEPIQsg--pCPIYIDYAHTPDALDNVCQTLRtllpSgG------KLIVVFGCG 379
29840139  309 QhCNGDLQQL---ISLAANVEsPRGRLEPVFsg--pCPIYIDYAHTPDALENVCKTLHallpEqG------KLIVVFGCG 377
16752621  309 AsLRCDLEDL---LEKIGLCQpPPGRLDPVLmg--pCPVYIDYAHTPDALDNVLTGLHellpEgG------RLIVVFGCG 377
15618333  309 AsLRCDLEDL---LEKIGLCQpPPGRLDPVLmg--pCPVYIDYAHTPDALDNVLTGLHellpEgG------RLIVVFGCG 377
15835951  309 AsLRCDLEDL---LEKIGLCQpPPGRLDPVLmg--pCPVYIDYAHTPDALDNVLTGLHellpEgG------RLIVVFGCG 377
283782955 485 GDKAVDRRKEIVEAAQNRIeQFIFTTEDTDTEDVMHICEDMQSYVtnpnvsSRIIIDRAEAIECAYNDAaSSEqkngrlN 564
166154480 378 GDRDRVKRPLMAKVSEHYG-FSFVTSDNPRTEDPDQIIADICKGFst--dhYVVESDRKLAIEKAISMA-SDK------D 447
166155355 378 GDRDRVKRPLMAKVSEHYG-FSFVTSDNPRTEDPDQIIADICKGFst--dhYVVESDRKLAIEKAISMA-SDK------D 447
237802692 378 GDRDRVKRPLMAKVSEHYG-FSFVTSDNPRTEDPDQIIADICKGFst--dhYVVESDRKLAIEKAISMA-SDK------D 447
62184995  378 GDRDQSKRKIMAQVVEKYG-FAVVTTDNPRGEDPEKIINEICSGFlk--rnFSIEIDRKQAITYALSIA-SDR------D 447
89898439  380 GDRDRSKRKIMAQVVEKYG-FAVVTSDNPRGEDPETIVNEICSGFvk--rnFSIEIDRKQAITYALSIA-SDR------D 449
29840139  378 GDRDQSKRQIMAEVVERYG-FAVVTSDNPRGEDPEEIIKAICSGFvk--rnFSIEIDRKQAITYALSIA-SDR------D 447
16752621  378 GDRDRSKRKLMAQVVERYG-FAVVTSDNPRSEPPEDIVNEICDGFys--knYFIEIDRKQAITYALSIA-SDR------D 447
15618333  378 GDRDRSKRKLMAQVVERYG-FAVVTSDNPRSEPPEDIVNEICDGFys--knYFIEIDRKQAITYALSIA-SDR------D 447
15835951  378 GDRDRSKRKLMAQVVERYG-FAVVTSDNPRSEPPEDIVNEICDGFys--knYFIEIDRKQAITYALSIA-SDR------D 447
283782955 565 ILLAIGKGDERWIKNKRKHVPYEGDSFVIKRLFGL 599
166154480 448 IVLVAGKGHEGYQIFKHQTIVFDDREVVCEALAAL 482
166155355 448 IVLVAGKGHEGYQIFKHQTIVFDDREVVCEALAAL 482
237802692 448 IVLVAGKGHEGYQIFKHQTIVFDDREVVCEALAAL 482
62184995  448 IVLVAGKGHETYQIFKHQTIAFDDKEIVLGVLSSY 482
89898439  450 IVLVAGKGHETYQIFKHQTIAFDDREVVHEVLSSY 484
29840139  448 IVLVAGKGHETYQIFKHQTIAFDDKEIVREVLSSH 482
16752621  448 IVLIAGKGHEAYQIFKHQTVAFDDKQTVCEVLASY 482
15618333  448 IVLIAGKGHEAYQIFKHQTVAFDDKQTVCEVLASY 482
15835951  448 IVLIAGKGHEAYQIFKHQTVAFDDKQTVCEVLASY 482
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