Conserved Protein Domain Family
HRD1

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COG5243: HRD1 
HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 227568
Aligned: 3 rows
Threshold Bit Score: 469.836
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
19113168   1 MKFILYVLASLVLFGLSVLLSLYSSANVYSATVMISQ--SPVHITIGLNVCLCLFFAIANALKTLLFGSLQTFELELLYE 78  fission yeast
19075085   2 KRIVAYGVSHFILLVIYTMKANHGGLTMYNVLTTTTRn-STAHILHATFLIFLMCSLTGRVIDG-VFGSLRSEEIASFNE 79  Encephalitozoon cun...
6324561    5 NRRKQLAIFVVVTYLLTFYCVYSATKTSVSFLQVTLKlnEGFNLMVLSIFILLNSTLLWQLLTKLLFGELRLIEHEHIFE 84  baker's yeast
19113168  79 QFWITLTEIMLAITVFREAISISFFMLLSTLMFARVFHSICSFRTE---RLQIQLTDQRFHIFSRLTCAYFVLSILDASL 155 fission yeast
19075085  80 SLLYFLTDFLLVVSTFDSDINFKNGLLFVMLLCVKSLSWLLGVRIK---RDVYASLYTLAYGISLFSGLMALLFTLS--- 153 Encephalitozoon cun...
6324561   85 RLPFTIINTLFMSSLFHERYFFTVAFFGLLLLYLKVFHWILKDRLEallQSINDSTTMKTLIFSRFSFNLVLLAVVDYQI 164 baker's yeast
19113168 156 IYLCFTS-----------------------EHLGDKSTRMLFVC-EFSVLLLNLTIEAS--------------------K 191 fission yeast
19075085 154 ---CIS--------------------------FIDGQILFL-----FEYALLVLASVKN--------------------- 178 Encephalitozoon cun...
6324561  165 ITRCISSiytnqksdiestslyliqvmeftMLLIDLLNLFLQTClNFWEFYRSQQSLSNennhivhgdptdentvesdqS 244 baker's yeast
19113168 192 LCIYLYEARHLDqvwDEKSTYLFRLEVCRDG----LRLLAYSLLFMYQFPYVSVPIYSIRQMYTCFYSLFRRIREHARFR 267 fission yeast
19075085 179 ICVMNLILSDDD---GKRSLHNFYIDIAYMG----ITLLAYVIFIGITSLSYRLPLNLFRSALTILDALVSKIKTFLSYL 251 Encephalitozoon cun...
6324561  245 QPVLNDDDDDDD---DDRQFTGLEGKFMYEKaidvFTRFLKTALHLSMLIPFRMPMMLLKDVVWDILALYQSGTSLWKIW 321 baker's yeast
19113168 268 QATRDMNAMYPTATEEQL---TNSDRTCTICREEMFHPDHppentdemEPLPRGLDMTPKRLPCGHILHFHCLRNWLERQ 344 fission yeast
19075085 252 RLCKDLEKCVE----------GSGDGFCAICMDG-METG--------------------KKLTCGHCFHLECLKMWCERQ 300 Encephalitozoon cun...
6324561  322 RNNKQLDDTLVTVTVEQLqnsANDDNICIICMDELIHSPN--------QQTWKNKNKKPKRLPCGHILHLSCLKNWMERS 393 baker's yeast
19113168 345 QTCPICRRSVIGNQSSPTgiPASPNVRATQIATQVPNPQNTPTTTAVPGITNSSNQGDPQASTFNG--VPNANSSGFAAH 422 fission yeast
19075085 301 QTCPICKSPLAFDMRK-----ESFVVGNEYISGIPVTIDN---------------------------------------- 335 Encephalitozoon cun...
6324561  394 QTCPICRLP-VFDEKGNV--VQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIriVPTQNIDTLAMR 470 baker's yeast
19113168 423 TQDLSSVIPrrialrdGWTMLPIPGTRRIptySQSTSTTNPSATPTTGDPSNSTYGGPQTFPNSGNNPNFNRGIAGIVPP 502 fission yeast
19075085     --------------------------------------------------------------------------------     Encephalitozoon cun...
6324561  471 TRSTSTPSP-------TWYTFPLHKTGDN---SVGSSRSAYEFLITNSDEKENGIPVKLTIENHEVNSLHGDGGEQIAKK 540 baker's yeast
19113168 503 gWRLVSSNTQSL 514 fission yeast
19075085     ------------     Encephalitozoon cuniculi
6324561  541 -IVIPDKFIQHI 551 baker's yeast
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