Conserved Protein Domain Family
PRK03991

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PRK03991: PRK03991 
threonyl-tRNA synthetase; Validated
Links
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Statistics
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PSSM-Id: 235190
Aligned: 58 rows
Threshold Bit Score: 821.81
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
147920005   1 MQLLLIHSDFIEYEVK-KSTPVAEKIEDAVRSGRMEEALTAFAAVEKPDESNPQYVIEKGLEAIIKVAEQVKTTRVMLYP 79 
218884527   4 LRILLIHARRFSYSVVkPAVEEPEPLEEGGKTLMLENVLVVFTSIERGDD---ESIISSAVNEVINVFNQVKASSILLYP 80 
126459249   1 MRVLYIHAERFSWESR----EPALDIRDEPGSGAAANALVVFVSVERGDSSD-EEFLRRVARDVVETAEKVKATAVVIYP 75 
18312849    1 MRVLYIHAERFNWEPR----DPALDIRDEPTSGNANNALVVFTSVERGDVPD-ENFLRAVASDIIDVAKKVKASAIVIYP 75 
126465876   1 MRILTIHARKFHYKALsQALDKPEELTNENKEGFFENVLVVFTSVEEGDN---EKVVEKAVTEILDIANRVKPKTILLYP 77 
297527450   1 MRILTIHARKFRYKALsQALDKPEALTGENKEGFFENVLVVFTSVEEGDN---DKVVEKAVAEILDVANRVKPKTILLYP 77 
124027839   1 MRVLLIHAKRFIYRTRmKAIPEAEDINGVQGEGSFENALVVFTTVESRDTSNPKEVVETAAKDIVEIASKVGAKTIVVYP 80 
296242499   1 MKLLLIHSRTFQYTPIePAVKEPEPLPEGAGEERFENALVVFTTVENGDD---SSVAERARDEILGVAEQVKPSVIVLYP 77 
159041076   1 MRLLLIHARSFSFEVRdKAVENPEPLTEELKRGSADNTLVVFTTVEENDNDSP-SFLERVADDVLDVAGKVKASSVFLYP 79 
305663857   1 MKLLTIHAKEFMFKPTeRAL---DIFDEPITSERYENVLVAFITVEEDDEKDIDGVVTQAVNEIIDIYKKVGARGIVIYP 77 
147920005  80 YAHLSANLSSPKMAVEVLKGLEAAL-K--GKGFEVARAPFGWYKAFTIKCKGHPLSELSRTIRPEgveavsvtpavaaek 156
218884527  81 YAHLSPDLAPPFEAVKILNAFYTAL-K--NTGLQVYKAPFGWYKSFTLECYGHPLSELSKTIKKS--------------- 142
126459249  76 YAHLSNDLARPYVAKEVVNKLYEVVkS--EFKGEVYKAPFGYYKAFEVKCLGHPLAELSRSFKPEe-------------- 139
18312849   76 YAHLSSDLARPYTAREVLNKLFEVVkS--QFNGEVLKAPFGYYKAFEIKCLGHPLSELSRSFKPEe-------------- 139
126465876  78 YAHLSSDLASPSQALEIMKLLEQKLrG--KTDLEVYRAPFGWYKEFMLDCYGHPLSELSKTIRIT--------------- 140
297527450  78 YAHLSSDLASPSQALEIMKLLEQRLrS--RIDLEVRRAPFGWYKEFMLDCYGHPLSELSKTIRIT--------------- 140
124027839  81 YAHLSQKLAPPHQAKNILAMLELEIkKlaSDKFEVSRAPFGWYKEFELHCHGHPLSELSRNYEAK--------------- 145
296242499  78 YAHLSSDLAPPSVAMSVLEDLGAKLsA--TSKIPVHKAPFGWYKSFRIECLGHPLSELSKTVRKT--------------- 140
159041076  80 YAHLSPNLAPPPKAITILNALYETLkG--KASIPVYRAPFGWYKAFNISCLGHPLSELSRTITPQ--------------- 142
305663857  78 YAHLSSSLAAPSVAKEIVSKVYEVL-K--NEGFNVVKAPFGWYKEFELHCYGHPLSELSRTIRPT--------------- 139
147920005 157 pevvSEAVKAEEKLKSYFYILDVDGqLKDPKTFDYKGHDk-LKAFVDYEMAKKRAVDRE-PPHVELMRRLELaDYEPGSD 234
218884527 143 ------ETVAKRIIEKKFYIMTPDGsLHDPTSFDYTNYPe-LKILVDKEVFGKELTGGE-NRVNEYCRKFGF-EWEPMSD 213
126459249 140 ----ARVAKAVEERRDVYLVLTPDGrEHDPAAYSPADPD--LKALIDKEVFKRELGGGE-PRYLDYLRKFGF-EWEPMSD 211
18312849  140 ----GRADRRAEERRDYYVIITPNGeEHDPAKFNYANYGd-LKALVEKEVFRKELGGGE-PKYLEYLRKFGF-EWEPMSD 212
126465876 141 ----GGGEVVRRELKKEFYILTPDGkVYDPEKFNYDKYPd-LKILVDKEVFGKELPGGV-NRVNDYCRKFGF-EWEPMSD 213
297527450 141 ----EGGEVVRRELKKEFYILTPDGkVYDPEKFDYDKYPd-LKILVDKEVFGKELPGGV-NRVNDYCRKFGF-EWEPMSD 213
124027839 146 -------TTARVEVKKKYYVLTPEGeVYSPEEFLEKASPe-FRAVIEKEALGKEIGGVE-NPVNKLCAKFGF-EWEPLSD 215
296242499 141 -----GSVGQKRVVEKKFYIMTPDGsLHDPASFDYSNYPe-LKILVDKEVFGRELEGGE-NRVNDYCRKFGF-EWEPMSD 212
159041076 143 ----ESAPQRKPYTRDYYVIVSPDGsIHDPASYSFSERDadLKVLVDKEVFKRELEGKEqPRYIDYCLKFGF-EWEPLSD 217
305663857 140 ------IRERRRTIEKKYYILTPDGnIYKPGEFEFSNENieLKILVDKEVFKKEIEGGQ-GKVLQYLKKFGF-EWEELSD 211
147920005 235 PGNMRWYPKGRAMKNMLEQFVLSEAAKKG--AMEVETPIMYDMEHPTLKKYLDRFPARQYTVIAdKKNLFLRFAACFGQF 312
218884527 214 HGHMRYGPHATVIMEAVMRYSWMVAQSLGipVFKVMGSNMFNLKEKPVYEHAVLFGDRLYEVQLdEDRFILRYAACHQQF 293
126459249 212 VGHMRYGPEATVMMELVEDYAYQVAKSLGipVFKIRGTNMFKLSEKAIETHARLFGERLYIVESdT-DLILRYAACFQQF 290
18312849  213 AGHMRYAPEATVMMELVEDYSYIVAKSLGipVFKIRGTNMFKLSEKAIESHARLFGERLYIVESdT-DLILRYAACFQQF 291
126465876 214 HGHMRYGPHAVIIMESIMQYSWNIVRSLGipVYKVMGTNMFNLSEKPVLEHALLFGDRLYELKVdNEKFVLRYAACHQQF 293
297527450 214 HGHMRYGPHAVVIMDSIMQYSWNVVRSLGipVYRVMGTNMFNLSEKPVLEHALLFGDRLYELKVdNEKFVLRYAACHQQF 293
124027839 216 YGHMRYEPHATLMIEAVGEYAWILARSLTipVLKVKGTNMFDLAEKPVYEHAALFGDRLYELWAdKKHLVMRYAACHQQF 295
296242499 213 HGHMRYGPHGVVMMESVFRYSWKVANELGipVFKVMGTNMFNLKERPVYEHAELFGDRLYEVGLdEDRFVLRYAACHQQF 292
159041076 218 VGHMRYGPYATVMLELLDDYSYQVAKSLGipVFKVKGTNMFRLSDKAISEHAGLFGERMYITESdE-ELVMRYAACFQQF 296
305663857 212 HGHMRYEPHATVILEAVMQYSWIVANSLNipVFRVKGTNMFNVNAEAVKQHAELFGERMYEVRIdNDRYILRFAACYQQF 291
147920005 313 LMNHDMTISYRNLPLKMIELTRySFRKEQRGELVGLRRLRAFTMPDMHTLCTDMDGAIKEFGDQYEMCINTLDTIGIdik 392
218884527 294 AMLRDWVISYKDLPFGVFEVAD-SYRLEQRGELALCFRLRKFYMPDLHILTRNIGEAIDVSMRVQAKIHEEAGKAGR--- 369
126459249 291 AMAKDWVISYRNLPFGMLEIAD-SYRHEQPGETVVLFRLRRFYMPDLHIFTKDLAEAVEVSYKVHEAIFREIGKLGR--- 366
18312849  292 AMAKDWVISYKHLPFGMLEIAD-SYRHEQPGETVLLFRLRRFYMPDLHIFTKDLKEAMEVTYKLHEVIFREIGKLGR--- 367
126465876 294 AMLRDWIISYKNLPFGMFEVAD-SYRLEQRGELNLCFRLRKFYMPDLHILNRDLNEAIKISRIVQDKILEEIAKIGR--- 369
297527450 294 AMLRDWIISYKNLPFGMFEVAD-SYRLEQRGELNLCFRLRKFYMPDLHILNKDLDEAIKMSRIVQDKILEEIAKIGR--- 369
124027839 296 SMLKDYVLSYRDLPLGMFEIAD-SYRLEQSGEVTLCFRLRRFYMPDLHILARSVEEAVKIAEELQKIIHREAEKLGQ--- 371
296242499 293 AMLRDWVISYSHLPFGAFEVAD-SYRLEQRGEVALCFRLRKFYMPDLHIFNKNLEEAVRVSRIVQEKILEEAGKLGR--- 368
159041076 297 AMIKDWVLSYRNLPLGMLEIAD-SYRYEQPGETVLCFRLRRFYMPDLHIFVKDLKEAMDVGLRLHAKIFEEIRRIGR--- 372
305663857 292 SILKDWVLSYRDLPMGMFEIAD-SYRYEQRGELVLGFRLRRFHMPDLHILTKDLEEAKRIAMIVRNKIVEEARKIGR--- 367
147920005 393 tDYEVAIRFTKDFYNNNTPFIQSLVKRAGKPVIVEMWEERFFYFVLKFEFNYIDSLNKASALSTVQIDVENAERYDINYV 472
218884527 370 -SYVALYNITDEFLEKYRDKLVEFVKREKYPVLLAVIPSGIYYWVLNVEYHIIDNLKRPREIATFQIDVGNGRRFNIAYV 448
126459249 367 -TYVSLYNVTEEFYKSHRDYLVELARREGKPILVRILPTQKYYWVLNVEYHIVDELGRPREIATFQIDVGNAQRFGIKYV 445
18312849  368 -TYVSLYNVTEGFYKNHRDYLVELARREGKPILVRVLPGQKYYWVLNVEFHIVDELGRPREIATFQIDVGNAQRFGIKYV 446
126465876 370 -KYVALYNVTSDFFDKYRDILIEFVRRENYPVLVSVIPSGIYYWVLNVEYHIIDNLNRPREIATFQIDIGNGERFNITYT 448
297527450 370 -KYVALYNVTSDFFEKHRDVLIEFVRRENYPVLVSVIPSGIYYWVLNVEYHIIDNLNRPREIATFQIDIGNGKRFNITYT 448
124027839 372 -TYYAVYNVTEDFWEEKRNLLLELVRRDGKPALITVYPAGIYYWVVNVEYHIVDSAGRPREIATFQFDVGNAKRFGIRYV 450
296242499 369 -KYVALYNVTSDFLENHRQELLEFVRRENYPVLLAVIPGGIYYWVLNVEYHIIDNLKRPREIATFQIDVGNGRRFNITFV 447
159041076 373 -DYVSLYNVSKEFFDQNKDYLVELARREGKPILVRVLEGAKYYWVLNVEYHIIDELKRPREIATFQFDIGNAQRFGIKYR 451
305663857 368 -EYQAIYNITEDFFNTNFEYIVELVRAEGKPVLVVLYPPGLYYWVINVEYIIIDELKRPREIATWQIDVGNAKRFGIKYV 446
147920005 473 DQNGNRQRPIILHCSPSGAIERCIYGLLEKEAMEsEKGAVPMLPVWLSPTQVRIVTI---SEKHVPFAEALADRMCN--V 547
218884527 449 DEKGEKHHPVIIHTALLGGVERYIYMVLDTGALIeASGQTPYIPTWMSPVQVRIVPV---SKEYNEHAFKIAGEILShgF 525
126459249 446 DENNQVKYPVIIHTAIIGSVERYLYAVFDTIAKAeREGKTPRLPTWLAPVQVRIIPV---ARDNLKFAMEVADKLEEagI 522
18312849  447 DENNQIKYPVIIHTAILGSVERYLYAVFDTMAKMeKEGKVPRLPTWLSPVQVRVIPV---SKENLKYAISIADVLEAegI 523
126465876 449 DEKGEKHHPVIIHTAIIGGIERFIYTIFDTAALMeKEGKTPYIPTWLAPVQVRIIPI---KNEYLDYAEKVAEKIENagF 525
297527450 449 DEKGEKHHPVIIHTAIIGGIERFIYTIFDTAALMeREGKTPYIPTWLAPVQVRIIPI---KNKYLDYAEKVAEKIENagF 525
124027839 451 DENNKEHYPVIIHTALIGSIERYIYMVFDAAVKMeRRGQTPYIPTWLAPIQVRLIPVnpsSEQQLSHAEKVASLLERhlI 530
296242499 448 DEKGEKHHPVIIHTAILGGVERYIYMILDTAAIAeANGQTPYIPTWISPVQARIIPV---SKEYVEHALKIAVELQNqgF 524
159041076 452 DEGNNIKYPVIIHTAILGSIERFIFALLDTAAINeANGKVPALPTWITPVQVRVIPV---SSGYNEGAIELARRIEEagF 528
305663857 447 DENGVERHPIIIHTAILGSVERYIYMVFDTVARSeSENKPPTLPLWLSPIQVRVIPI---SKETLTYAINVAKELSRhgI 523
147920005 548 RVDIDDREETVGKKIRDAGKEWIPYVVTIGDAEMNGDKIPVVVRAESQqnkpaKVEMTVEELVERIHKETACLPYRPLPV 627
218884527 526 RVDVDDRDETLGKKIRDAGKEWIPYIIVVGEREVNTGTINIRVRRSND-----QRVMKLEEFIKLLEEEVKGYPRVEMTL 600
126459249 523 RVDVDDRDETLSKRIRDAETSWVPYVCVVGSKEEETGTLSVRIRGEG------QAKMTAEELIKRVREETRGYPTRPLYL 596
18312849  524 RVDIDDREETLSKKIRDAETSWIPYIVVVGSKEEAEGVIAVRERGGG------QYKIRLEELVKKLKDETRGYPQRPLYL 597
126465876 526 RVDIDDRGESLGKKIRDAGREWIPYIVVIGEREVRSNTINVRIRRTND-----QKVMVTDELIRILEEETKNYPRVSLTM 600
297527450 526 RVDIDDRGESLGKKIRDAGREWIPYIVVIGEREVKSNTINVRIRRTND-----QKVMVTDELIRILEEETKNYPRVSLTM 600
124027839 531 RVDIDDRQLSLGRRIRDAAREWIPYIAVIGDREVETGTVNVTIRRTND-----RVAVKPEELLEMVLKDLEGYPRVQSTL 605
296242499 525 RVDVDDRDETLGKKIRDAGREWIPYIVVVGEREVKTNTLNVRIRRSND-----QKAMSLEEFARILREETRGYPLVESTM 599
159041076 529 RVEVDDRDETVGRKIRDAETLWVPYIVVFGEREAKTGSLSVRVRGVG------QVSMSIEELLNRLNEETKGYPRKPLTA 602
305663857 524 RVDIDDRDESLGKKIRDAGIEWIPYVIVIGEREMKTGTINVRIRKDGI-----QRVMHIDEFIKLINEELNGYPRIESSL 598
147920005 628 VRSLAKRPKFV 638
218884527 601 PVSVASRPLFS 611
126459249 597 PRLLSQRPTRG 607
18312849  598 PRLLSQRPSRF 608
126465876 601 PKYLSKRPIPS 611
297527450 601 PKYLSKRPIPS 611
124027839 606 PRYVSKRPTLV 616
296242499 600 PLRLSQRPLFS 610
159041076 603 PMLLSIRPPLP 613
305663857 599 PMFLSKRPRLY 609
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