Conserved Protein Domain Family
SLC6sbd_NTT5

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cd11502: SLC6sbd_NTT5 
Neurotransmitter transporter 5; solute-binding domain
Human NTT5 is encoded by the SLC6A16 gene. NTT5 is expressed in testis, pancreas, and prostate; its expression is predominantly intracellular, indicative of a vesicular location. Its substrates are unknown. This subgroup belongs to the solute carrier 6 (SLC6) transporter family.
Statistics
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PSSM-Id: 271392
Aligned: 7 rows
Threshold Bit Score: 750.8
Created: 8-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
  next features
Feature 1: putative glycosylation site [posttranslational modification site], 1 residue position
Conserved feature residue pattern:NClick to see conserved feature residue pattern help
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
Q9GZN6       103 RPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGcSFAAIYIFMLFLVGVPLLFLEMAAGQSMRqGGMGVWKIIaPWI 182 human
EDM07381      89 WLLWSSKAEYILALMGYLVMPSGLLRFVTCWVHKGSwSFFIAYLLMLFGLGIPLLFLEMAVGQRAQqSSIDLWKTLsPWF 168 Norway rat
EDL22834      48 NHFQAKKTENILILVAFSIGLGSTWRFPYLCHQNGGgSFLLMYFILLLLLGIPLMYMEMVIGQWLRmDNIQAWKYLvPWL 127 house mouse
EHB06263      71 RPLWPRTVEYILTLMGYIVKPANIWSSVYLWLHKGGgTFFFIYTVILLIVGTPLLFLEMAVGQRMHrNSMDTWQIIaPWA 150 naked mole-rat
DAA19772      79 RPIWANKTEYLLAQVGFSVGLSTIWRFPYLCFHNGGgSFLIIYILMMFLVGIPLLFLEMAAGQRMRqGSIGVWKVIsPWI 158 cattle
XP_002917955  39 YFAQTKRTKNILMQVAFSIGLGSIWRFPYLCHRNGGgSFILMYFFMLLLFGIPLLYMEMIMGHWLRvNNIRVWKQLiPWL 118 giant panda
XP_003406559 107 RPLWSNKVEYILAQVGYSVGSMNIWSFPNLWIQNGG-VFLVFYILMLFLIGVPLLFMEMASGQRLRqGSLGVWKLTsPWM 185 African savanna...
Feature 1                                                      #                                 
Q9GZN6       183 GGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFqFPVPWEKCPLTMNssgf-dpeCERTTPSIYFWYQQALKASDRIEd- 260 human
EDM07381     169 GGLGYSMVMVCLITNTYLNVFNSWILFYMSHIFhFVVPWDRCPLQKNssdf-dpeCEQATSYTYFWYRQTLKASDSIEd- 246 Norway rat
EDL22834     128 SGVGYSNILACVLVVLYNSALVSWSLFYLGQSFdYPLPWQNCPLVENlsmvagntCLWSEPHQYFWYHTLLQASNQMEeg 207 house mouse
EHB06263     151 GGVGYASFIMCFITSTYTNVLNAWILFYLSHTFqFPLPWEKCPLLKNssdf-dpeCAQTTPSMYFWYQQTLKVSDRIEd- 228 naked mole-rat
DAA19772     159 GGVGYTSFMVCIIVGLYYSVLMAWNLFYLVQSFqSPLPWLLCPLSKNssi--dseCARTSPTTYFWYRKVLKATDEIEi- 235 cattle
XP_002917955 119 GGIGYASILVCILMSLYNSIILTWSISYLGNSFdNSLPWNQCPLVKTinvt-dlsCLRTVTHQYFWYHTTLSASGHIEeg 197 giant panda
XP_003406559 186 TGLGYTTFLVCFIEGLVFNLVNCWSLLYLSQSFqFPVPWETCPLVKNssef-dpeCARTTPSMYFWYRKTLKASDTIEd- 263 African savanna...
Feature 1                                                                                        
Q9GZN6       261 gGSPVYSLVLPFFLCWCLvgaFMINGLKSTGKVIYVLVLLPCFIIVGFFIRTLL-LEGAKFGLQQLVVAKisd-vyNMSV 338 human
EDM07381     247 gGQPSFNLAMFLFLAWCLicvFMVNGIKSLGKVLCVLLQVPYFIIICFLVRTLSmGNGIGYGLNYLLILEvar-isDLTM 325 Norway rat
EDL22834     208 iEVLVLNVTLCLFATWIFlyvTMVTRIKISVLMMIFSILFSNVLLLCFFIRTLF-LNGSVRASLWRLVTIelsilsSLDA 286 house mouse
EHB06263     229 gGPVVSSLSLPFFVSWCLvsaFMIKGLKFLGKGMFILMSLSYIIFFCFFIWSLH-LEGAKYGLKHLLAAKmsa-vyDLSV 306 naked mole-rat
DAA19772     236 dGKPVMHLSASVLVIWLIiciSMIKGPKSTGKMLYISVLLPYIILFSLLIRSLT-MKGAYFGLKNLLAAKvpa-lySVEV 313 cattle
XP_002917955 198 vEALVLHLTLGIFAAWCLlflTMITKLKTSMTILIFTVLLPYILLLCFLIRGLF-LEGAIASLRRMVTTElsa-waSLDL 275 giant panda
XP_003406559 264 gGVLIPSVTLSLLLIWFLtglIMINGLKSTGKALYVLVLLPYLILLCFLIRSPL-LEGASFGLQHMLVFKkvsiedSISI 342 African savanna...
Feature 1                                                                                        
Q9GZN6       339 WSLAGGQVLSNTGIGLGSVASLASYMPqsNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWATvithrccernaeillkl 418 human
EDM07381     326 WCQAGIQVLFDIGLGFGPVISLSSHMSdfNNCLKDAFLMGLFKIVTLLITTPFFLSILGFWATitthhcckkntnkllml 405 Norway rat
EDL22834     287 WRQAGGHVLYSLGLGMGTIITFSTYQPrgENYIKWASFVAMVNLATSLLSSFVIFLVMGFWTTtsgtmcikrsvsnlinl 366 house mouse
EHB06263     307 WSVAGGQVLFDLGLGFGPIASLSSHMPqsNNCLGDAFVMALIYLVTLLFMTPFILALLGFWATvlthrcteknmemllml 386 naked mole-rat
DAA19772     314 WRRTGNQLFLSLGPGFGSFTAISSYIPrsNNCVIDAYAVAFLNLLVSLTTTVFVFAVMGHLATknnekcylmnaekvmdl 393 cattle
XP_002917955 276 WRQAGGHVLYSLGLGMGTTINFSSYKAgeDNYIQVASLVALVNLGTSLLVTSIIFIVLGFWTTtsgptcveksvtnlmnl 355 giant panda
XP_003406559 343 FFQVGMYVLLSLGLGLGIIASFATYMHpsNNCLTDAFLMALVNLGTSLIATPVIFAVMGFWATviahrcseknveilrnl 422 African savanna...
Feature 1                                                                                        
Q9GZN6       419 inlgklppdakppvnllynPTSIYNAWLsglpqhiksmvlrevtecnietqflkasegPKFAFLSFVEAMSFLPpsvFWS 498 human
EDM07381     406 i-aqgilppeveppdlnddPISIYNSWLnslppplrsavlsmvpecniqkqfmriedsPRFLFLIFTEVISLLPgsaFWT 484 Norway rat
EDL22834     367 iangvlpkaawppgdiihkPPLEYLAWInqlpnnlksqvihqtlpcsiliqkekimegPGLSYVAFSQAISLFPgssFWA 446 house mouse
EHB06263     387 vnmgilppeakppddlnndPTSTYSSWLsglaqdikslvlskvskcdrelrilqakegPGFVFLSFAEAASFLPrsiFWC 466 naked mole-rat
DAA19772     394 vtaqvlppeahppdslyhdPSAIYPKWLnnlpehiksrilpnltdcdlskelnkvmigPGVVIVTFSDIVSLFSgptFWS 473 cattle
XP_002917955 356 ikkgvlpqdakppedilllPALDYLEWIsnlpqhlqyqvihfsptcsiktqkekfmqgPGLAFAAFSQAVSLFPgasFWA 435 giant panda
XP_003406559 423 islgelppeaqppanisdnPASVFTTWLenlphsikkmvlskvseckiqdqiskvkkgTSFAYLAFIEAMSFIPgsaYWS 502 African savanna...
Feature 1                                                                                        
Q9GZN6       499 FIFFLMLLAMGLSSAIGIMQGIITPLQdtfsffrKHTKLLIVGVFLLMFVCGLFFTRPSGSYFIrLLSDYWIVFPIIVVV 578 human
EDM07381     485 VLFFLALLGLGLCTNLMYMLGNILTLQdtfpfcrRQPRLLTVGVSMTTFLCGLIFIQPSGIYYFsLLSEYWVAVPIITII 564 Norway rat
EDL22834     447 IIFFMSLAIMGLGTMLTLLEGIVLPLQksistfaKHPNLVQVLVCLGGFLGSLVFSSRPGSYVVfLFDDLLVPMVLIIIV 526 house mouse
EHB06263     467 ILFFLMLLLLSLSTTIGFMQGLIIPLQdpssflrKQTKLLTGSISMLLFLCGLYFTRPPGVYIIkLVREYWTPMPIIFII 546 naked mole-rat
DAA19772     474 IVTFLLLVNLGLSTVIGIIQGIITPLQdtfsslrEHSKLLTVGVCVPMFLGSLLFVRPSGSYYVnLLDDYWVSLPLFFIV 553 cattle
XP_002917955 436 ILFFLALVITGLNTLLRILEGIVYPLQdsisifrRYPKLLSALVCLGGFLGSLIFTSHPGSYIMsLFDECLVPLTLIIIV 515 giant panda
XP_003406559 503 ILFLLMYLSMGLTAMVGIMQGIITPLQdtfsfsrKHPKLLIVNVSVLMFLCSLFFAQPSGFYFFrLLNDYWINFPILFLI 582 African savanna...
Feature 1                                                                                        
Q9GZN6       579 VFETMAVSWAYGARRFladltillghpispIFGWLWPHLCPVVLLIIFVTMMvhlc-mkpiTYMSWDSSTSKEVLRPYPP 657 human
EDM07381     565 LCETLAVAWAYGAKRFladmmallsrpifpGCSWLWRYVSPVVLLGLLLFICiylv-qgplVYMAWDSSTSKEVVRYFPM 643 Norway rat
EDL22834     527 VIQNLSLAWLYGIKRFraevfgqlgslvwsPFTFLWSYVTLPTLLVLLTIYFlnlyysgspYYVSWNDSMSHEVKQPYKK 606 house mouse
EHB06263     547 ICENIAVAWAFRAKRFlgdlmnlaqgftlrFYSWVWSYLTPVMLLVMFVALLvqrc-vkpiTYLAWDSSNSTEVTREYPS 625 naked mole-rat
DAA19772     554 ILETIAMAWIYGARRFltdlsimmghpispIYRWLWCFLSPFVLLVLFLSTLihls-vkeiTYLAWDSRISHEVTRIYPS 632 cattle
XP_002917955 516 AFQNVALAWIYGARRVreeifgdlgrllwsFFTVLWCYVTLPGLLALTTICImqlyqteppYYIAWNSSMSQEVEQPYLQ 595 giant panda
XP_003406559 583 TLENVAIAWSYGAKRFlaemmilmghpispIYRFLLCCLCPFVLLVLSAVTPiyvy-vqdfIYLAWDSSTSEEVPREFPS 661 African savanna...
Feature 1                        
Q9GZN6       658 WALLLMITLFAIVILP 673 human
EDM07381     644 WSLMLIAGLSAVVLMP 659 Norway rat
EDL22834     607 IPLGWVTFLSVLALLP 622 house mouse
EHB06263     626 WALLLMIILLLIVIAP 641 naked mole-rat
DAA19772     633 WAKALLIFLVVITVLP 648 cattle
XP_002917955 596 STLGWVTFLSILTFLP 611 giant panda
XP_003406559 662 WAFNSLIIFTVIVFLP 677 African savanna elephant

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