Conserved Protein Domain Family
ribokinase_group_A

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cd01942: ribokinase_group_A 
Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.
Statistics
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PSSM-Id: 238917
Aligned: 30 rows
Threshold Bit Score: 192.526
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Conserved Features/SitesClick to see Conserved Features Help
 
substrateATP binding
Feature 1:substrate binding site [chemical binding site]
Evidence:
  • Comment:based on homology to other members of the family
  • Citation:PMID 9519409

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                              #                        
ZP_00130917   2 SIFISGSLAYDRI-----MNFPGKfsdhilpdkihilnvcFLIDRLEEKRGGTAGNIAYSLALLGekPTILATVGKDFdr 76  Desulfovibrio de...
AAB84910      4 DAVGLGALNMDQLhmverIAGPDEe---------------TFVRGLVESCGGSAANTMIGLSRLGlrTAHIGKVADDReg 68  Methanothermobac...
AAB86307      3 RVVSVGTCNMDFIfrvqeFVEPDSe---------------MYIDDIHILPGGSALNFAVWISALGfsSDIVAATGGDMyg 67  Methanothermobac...
AAD00536      2 IVASIGNLNFDIYlkvseLPGPDEn---------------VEALDLYTGGGGSAANFAVAIAKMGlsARFIGAVGEDPlg 66  Pyrobaculum aero...
NP_146902     7 QAVAVGHALVDLRly--vERIPGVde-------------eAVIKDETRSVGGSAANVAVVLRRLGvqSGIIGKIGLDDfg 71  Aeropyrum pernix K1
NP_148387    10 THIAVGNINLDISls--vDRLPGPee-------------vVFARDAWIGVGGAATNYAIAVAQLGqkPVLVAVAGREMer 74  Aeropyrum pernix K1
AAM02030      3 DVVGLGALNVDEL-----LYIPRMper----------ddsVPVERRVRRGGGSAANTICWLAHLGreVGFVGKVGSDDag 67  Methanopyrus kan...
NP_579615     4 DVICMGNLNYDITfm--lERFPEFhe-------------kVNAKKVYTGLGGSAGNTATWLSFLGlrVGFIGAVGNDDfg 68  Pyrococcus furio...
NP_126109     4 DVICMGNLNYDIVfl--mEKFPGIhe-------------kVNAKGVFTGLGGSAGNTATWLAKLGlkVGFIGAVGNDDfg 68  Pyrococcus abyss...
CAF18505    133 LVASIGNLNYDIYik--tHELPGLdq-------------sVDALDLYTGGGGSAANFSVAIARLGhrARFIGAVGDDVig 197 Thermoproteus tenax
Feature 1                                                                                       
ZP_00130917  77 --yEEVLTGLGLpqdgir--kmddqFTAGAYITTDQSDNQITgfNPAAMshpcgyqfngvtpenDLAIVSPGNLq----- 147 Desulfovibrio de...
AAB84910     69 gllRSNLSSEGVtdftv---vadtgRSGRVMGFVDPDGNRALyvDPGVNdtlrvde--vadealNTELLHLTSFagdgin 143 Methanothermobac...
AAB86307     68 eiiRSRLESEGVstgcl---svvekPTGMAFISVDGSGRRSIysYMGANaeleigt-pegrcirAADAVHLSGCy----- 138 Methanothermobac...
AAD00536     67 eisLRELRAEGVdvsfvkrvrgvrsGVVVVLVHPDGVKRMVS--YRGANlgltpa---dltvdkFAGVKHIHLAtgr--- 138 Pyrobaculum aero...
NP_146902    72 riaVDNLMREGVdisglr--vslrdRTGFSVVVRDKEGSITIysFKGAAeklepg---eidadaIGRSKHVHVAslrpdt 146 Aeropyrum pernix K1
NP_148387    75 lgvVDTLRRRGVdvsrvktvdrpsgVVVVMVVASDSHRSMVS--MRGANeellkyi-eeepldgVSGECHVHMAs----- 146 Aeropyrum pernix K1
AAM02030     68 dllLREFEEYGVdtsrv---vrgdgHSGTAFCLVSGDDRRILv-DPGVNdelrpde-vdldyirKARVLHTSSFiglr-- 140 Methanopyrus kan...
NP_579615    69 rlhLEFFEKIGVdtrgi---kvvdePTGVAVMMVIGEDKRIVk-YPGANrfkevk----enylkLARHLHLSSNpl---- 136 Pyrococcus furio...
NP_126109    69 rlhLEFFREIGVdtsgi---kvvndATGIAVTMVKGEDKRIVk-YPGANrwkevn----teylkRARHLHLSSNpiel-- 138 Pyrococcus abyss...
CAF18505    198 eiiLKELESEGVevryvkkigglrsGVVVVIVQPDGGKRMIA--YRGANmglspdd-ineaslgGVDHVHVASGrv---- 270 Thermoproteus tenax
Feature 1                                                                                       
ZP_00130917 148 ----dMVELPRKFrsm--gmrYIFDPGQQITAltgdsmLECINGAHMLVSNDYElem---------imKATGRTkaell- 211 Desulfovibrio de...
AAB84910    144 vqvevIEALDESVt-------VSLDPGHIYASrgvselSDILERTDILLTNQREl------------eLMTGSAdpeeaa 204 Methanothermobac...
AAB86307    139 -----VEVAQRVAei----reVYFSPGRLLAGygldvlEPVLRKTEVLFLNDDEleil-------tgsRKSGISrllg-- 200 Methanothermobac...
AAD00536    139 ---teLILKAKEIarei-gasISVDGGTALARkgleivRAAVEGVDVVFMNHVEaqlvanagdhksavEKLARElk---- 210 Pyrobaculum aero...
NP_146902   147 tlktvEIAKKRSIt-------VSWDPGRVLSKmgaerlANIISKVDIIFVNRNEa------------kNLTGYHdyrqaa 207 Aeropyrum pernix K1
NP_148387   147 -----VPPQALDFapg--gctLSYDPGGEAFKrpk-slWSRLPRVDWMFINTPEl------------kGMSGSGdlaaay 206 Aeropyrum pernix K1
AAM02030    141 -setsLETLKRTMkavadelmVTFSPATMVLRgws-ylEPYFEAADVVFLNETEa------------vHLTGDIeetlnr 206 Methanopyrus kan...
NP_579615   137 ----pLVEKAVNLaknl-gltVSFDPGEMEVP------KHIEEKIDILMMNEDEf------------kRKYGSLekite- 192 Pyrococcus furio...
NP_126109   139 --ireAVEKAKELgl-----tVSFDPGEMEVP------RDVEKELDILMMNEDEf------------kAKYGSLdrikd- 192 Pyrococcus abyss...
CAF18505    271 ----eLILKAKEVakrd-gksISVDGGTSLARkglevaAKALSGVDVVFMNQAEaklls-----sssdHRAALDviarn- 339 Thermoproteus tenax
Feature 1                                                       #  #                            
ZP_00130917 212 -----tmtdYIITTLGENGSRIDn---gEPVMVgiar---prqVLDPTGAGDAFRAGLLKGLTDGLDVAGAAKIGATCAS 280 Desulfovibrio de...
AAB84910    205 ---sllgigVVVVKMGARGVRAWd----GESVMvdal---steCVDTTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIAS 274 Methanothermobac...
AAB86307    201 -----vgvdYVVVTHGPGGASFFs---aDHSLEmkve---dagAIDTTGAGDAFAAGFMSEWLRGYEPLECLRGGHRAAL 269 Methanothermobac...
AAD00536    211 -------vgELVVTLGPIGAVAFk---nGRLLHvdaf---kvnAVDTTGAGDCFAAAYITMYLRGRDLYERLLFANAAAA 277 Pyrobaculum aero...
NP_146902   208 rhlkklgpkIVVIKLGASGSYILy---sDGEVFvpai--kperVVDTTGAGDSYAAGFIAGLLRGYTIEKASLYATIVAS 282 Aeropyrum pernix K1
NP_148387   207 r-llesglkRLVLKHGRGGATVVe---rGFCVTldrt--pvlePVDVTGAGDAFDAAFNIAVKAGWSVEEALRLAVAAGS 280 Aeropyrum pernix K1
AAM02030    207 ---laelveVTIVTRGSDPAIVQe---gTEISEvapepvpeedIVDPTGAGDAFAAGFIEGILRGEPADRCCERGHAVAA 280 Methanopyrus kan...
NP_579615   193 -----lksrIAIATLNGGGALVRde--nGNVYEirgl---sakAIDTTGGGDSFDAGFIYGYLNGWDVKDSAKLGMLLAY 262 Pyrococcus furio...
NP_126109   193 -----vkarIAIATLNGGGALVRdekgeVHEVRgls-----akAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAY 262 Pyrococcus abyss...
CAF18505    340 -----idarEIVVTLGDRGAMALs----GGEFLyvda--frlqALDTTGAGDTFAAAYIAARLMGLSLYERLLFANAAAS 408 Thermoproteus tenax
Feature 1                
ZP_00130917 281 FCVEHYGTQ 289 Desulfovibrio desulfuricans G20
AAB84910    275 RCIGGYGAT 283 Methanothermobacter thermautotrophicus str. Delta H
AAB86307    270 KVISRFGAF 278 Methanothermobacter thermautotrophicus str. Delta H
AAD00536    278 IKVTRPSAR 286 Pyrobaculum aerophilum str. IM2
NP_146902   283 IKVSRLGSN 291 Aeropyrum pernix K1
NP_148387   281 AKVLRRGSS 289 Aeropyrum pernix K1
AAM02030    281 ECLRIEGCR 289 Methanopyrus kandleri AV19
NP_579615   263 LTVQKVGAR 271 Pyrococcus furiosus DSM 3638
NP_126109   263 LTVQEVGAR 271 Pyrococcus abyssi GE5
CAF18505    409 IKVTRPGAR 417 Thermoproteus tenax

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