Conserved Protein Domain Family
CFAP54_N

?
pfam14858: CFAP54_N 
Cilia- and flagella-associated protein 54
This domain family is found in eukaryotes, and is typically between 542 and 565 amino acids in length. This entry represents the N-terminal region of the cilia- and flagella-associated protein 54 which is required for assembly and function of cilia and flagella.
Statistics
?
PSSM-Id: 464350
Aligned: 8 rows
Threshold Bit Score: 848.272
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EKC24872       57 DEEPSSRASDTLFELWNKYEPKLPKEYYQSKLIEVGDFLVLVK-----------------EYSIALWQCYDRYLMHFGNL 119 
EDO48350       64 DEEAYARGSNTLFNLWNNFEQRLPHDFFVQQMIATGDYLVSIRrmgithtllsmhtciltEYKIAQCQCYGRYLSSIRGL 143 
XP_023605588  102 KHEFNRRGAMSLFNIWTKYAPRLPTAYYNEKLLKVGDSLCEMK-----------------EYKLALLQCYGRYLQQFS-I 163 
Q96N23         99 KHEFRRRCATSLFNIWTKYAPRLPADYYNEKLLKVGDSLCQMK-----------------EYKLALLQCYGRYLQQFN-T 160  human
Q8C6S9        104 KYEFHRRCATTLFNIWTKYAPRLPSNYYNEKLLKVGDSLCQIK-----------------EYKLALLQCYGRYLQEFI-A 165  house mouse
3_pfamImport    1 DNGSHAKGIQILVEIWKKYKQRLPSKFYLERMLQIADFLFEIK-----------------LYQTAFWQGYSLHLQQFNSV 63  
XP_015207521   43 DYESYARGSKNVFEIWNKYKPRLPACYFEENLLLVADFLYRIK-----------------LYKMALWQGYGRYLQQFSSV 105  spotted gar
XP_008109087   60 ERDLHRRGVTALFNIWNNYKPRFPDWYYNEKLVKVGDQLVEMK-----------------EYKLALSHCYGRYLQQITSV 122  green anole
EKC24872      120 NVEEIT-D--VEAFKKIFFPGGFESHNAGLTFRALMGKSISMYQMVKAADPKLQNKQSVERCVLILNFLRLVMQVVLPKE 196 
EDO48350      144 NTLESCsDytLESFNNVYLPSGIEAATAEIALRALLGESISSYHVVIAEDPKLQNPETVSLSVDILKILRLITQAALHKE 223 
XP_023605588  164 SFDENIaD--IQQFKTVFFPNGIGDQTAANTFHALNGRNICSYQLVCNNDLNMQNKESVIQCLNILSSLRLTMQVALPQE 241 
Q96N23        161 NFDENKvD--VTQFKATFFPKGFKDKTAGLTFHALSGKNMCNYQLVCDSDENLKNKESVVQCLHILSSLRLIMQVALPQE 238  human
Q8C6S9        166 DFDEHKeD--VNHFKTVFFPKGFGDETARLTFHALSGKNICNYQLVCESDANLQNEESVRQCLHILSSFRLIMQVALPQE 243  house mouse
3_pfamImport   64 KITDIT-D--VDHFMSSFFPEGFDTDAFALKIRAMHGCALCMFE--REKRHTALSQKGLCELLRVLNFIRIMMQSLQPHE 138 
XP_015207521  106 IDNDIT-D--INQFKNIFFPRGFEADNAKLTFRALQGHCLCSFQLESENEGRLQSQASVQKLLDILAFLRLMMQAVLSHE 182  spotted gar
XP_008109087  123 NINKLE-S--VHELKTNFFPNGFKDPIATRTFHVLQVWLTCLYKMVCDDDIDLLNQESVKTCFRILTILQIIMQMTLPHE 199  green anole
EKC24872      197 TLCWLVYNGTVHIYSISRHLMSLGHSARTLEYLLWASMCMETSVPLLAVKYLPWRSTLYTAVCQCYFDCKQSQHAEAFAR 276 
EDO48350      224 SFCWLVFNGTVHIYSISRHLMALGYSNKVLEFLQWACMCMESSVPLMTVRYLIWRSTLYAATCQCYYDMKAANHAESFAR 303 
XP_023605588  242 HLCWIIFNGTVYIYTICRKLMVIGQSSKALEYLLWASVCMESSVPLLSIRYLTWRVTLYTAVCQCYYDCQAAIHGETFAR 321 
Q96N23        239 HLCWIIFNGTIYIYTICRKLMVIGQSSKALEYLLWASMCMESLVPLLSLRYLTWRATLYTAVCQCCYDCHAGIHGEAFAR 318  human
Q8C6S9        244 HLCWIIFNGTLYIYTICRKLMVIGQSSKALEFLLWASMCMESSVPLLSIRYLTWRATLYTAVCQCHYDCQDGIHGEAFAR 323  house mouse
3_pfamImport  139 HLCQQIYNGSLLIYNICRYLMTMNCSAQALEYLLWASISLELSITLMSAKYLPLIVTLYCAVCHCYYDNQAGSQAEKFAR 218 
XP_015207521  183 RLCWILYNGSLHIYTISRHLMAMGHSAQALEYLLWASVCMEMTVPLLTVKYLPWRATLYAAVCQCYYDCQAGLQAEVFAR 262  spotted gar
XP_008109087  200 HLCWLVYNGTIHMYTICRHLMIIGQSAKVLEYLLWACVCMESSVPLLAVHYLTWRATLYAAVCQCYYDSHCGMHGEIFAR 279  green anole
EKC24872      277 RGLAKINELSNLENLSSSVETPLSEITFRTATVKMAVMVFKRSVYETRRKPKALLRPKTRANLKEASHLTWPRTPSEKLM 356 
EDO48350      304 RGLTKVNELEDIERMSTSDATPMVARAFRQAKTRMQVMVFKRVVFETRKRPKGLLRPKTKPNLKDTVNQPWPRTPTERLL 383 
XP_023605588  322 RGLAKIDELRQLELMGSSQPPEASRRYYREATIKMAVMIFKRAVFESRRKNRSFFRPKVRVNLKEVQALPWPRTITERLL 401 
Q96N23        319 RALAKIDELRQLELMSSSKSQEESRRYFREATMKMAVMIFKRGVFESRRKNKAVFRPKIRINLREVQTLSWPRTVTERLL 398  human
Q8C6S9        324 RALAKIDELRQLELMSSSSSLETSRKYYREATIKMAVMIFKRGVFESRRKNKNVLRPKLRLNLKEAQSLPWPRTVTERLL 403  house mouse
3_pfamImport  219 RALGKINELAKLEEQNKLPASRETHRAYKEASIKLASMMFKHAVFEARRRPKHIRRIKSKNTLKDIPNGPWPCNTTERIL 298 
XP_015207521  263 RALGKVSELSQLQEMSVSPQSPETQRSFREATVKVAVMLFKRAVYEPRRKPKGLFRPKLKSNLKEIQNLPWPRTPSERLL 342  spotted gar
XP_008109087  280 RCLMKIDELKQMENISSSPLSVETKKKFKEATVKMAAMIFKRSLFESRRRPKGVFRPRVKANLKDMQSLLWPRTITERLL 359  green anole
EKC24872      357 ADMFEGSAAQFLCILESLTDTNRRILLTAPPASDsEVEILDVYAELFMAGQEILAGGgghrGSSIKP------------- 423 
EDO48350      384 ADQFTGTAAQFLAILEALSESNRRTLHCEAPASDaEDTITDVCAELFFAGMELIAGGggprQTHAAK------------- 450 
XP_023605588  402 DEMFDSTASRFLAVLEALSDSNRRTLQTGPIATD-EVEIRDVVSELFLAGRELLI------MSNTAV------------- 461 
Q96N23        399 DEMFDSTASQFLAVLEALSDSNRRILQTGPIVTD-EVEIHDVVSELFMAGKELLI------MSNIGA------------- 458  human
Q8C6S9        404 DELLDSTSSRFLAVLEALSDSNRRILQTGPLVTD-EMELRDVVSELFMAGKELLI------LSNVRS------------- 463  house mouse
3_pfamImport  299 MALFDSSPAQLLGILETLWDSTRRPLQSR--MPD-EPERQEVTLELLSAGMSILSGT--------ST------------- 354 
XP_015207521  343 VELFEGSAAQFLALLEALGDSTRRPLQTG--LPE-EPELQEVALELLFAGISILAGG----GGGGSAdrgeqdmsppppi 415  spotted gar
XP_008109087  360 MELFDCNSAFFLAILEALFDKNRRILTPGPPVPD-EIEIRDVISELCFAGMDILDG--------GGI------------- 417  green anole
EKC24872      424 --TSSVHIP---------ALagimkdaSIMDMASKGEDGSSIEGAIRLVKLAYSFEQWEVFDSLIENVLTYIRILNDNKF 492 
EDO48350      451 --HQQEIHP---------SVvdf-gaqGLMALVQEGSNGIPLQAVVKFVKQAFSYEQWETFNTLISPTLELLKQMTDSTG 518 
XP_023605588  462 --DGMLSFP---------KT-------SLLQFIIERKNIISIDTAVKFTKLAFNYEEWSLFESAAGQLIDFLQTQDDPES 523 
Q96N23        459 --DGMLDFP---------KT-------SLLELMIGRKDVISVDAAVKFIKLAFTYEEWSLFESSAVHLIYFLQRQDDPES 520  human
Q8C6S9        464 --NGKLDFP---------QT-------SLLEHVVEKRNALSVGASVRFAKLAFTYEEWGLFESLAGQLIHFLQKQDNPQS 525  house mouse
3_pfamImport  355 --TGESLVS---------LSalt-ptsTLMDLAIAGENKVPIRSAMRFIKILFRYKQTDAFTDLAREMQQVLSCVEGHSF 422 
XP_015207521  416 sgIRHSCSL---------LK-----------LTASGENGVSVEGAVKFVKLLFRYEQWEMFISLASLMIPLLQSLDAPMW 475  spotted gar
XP_008109087  418 --NTLSNTPmdvygiinaSS-------TLMQQILAGNNGVSAAAALRFLKMVFSYEEWDTFDHAVMLFVSFLQNQNRTEW 488  green anole
EKC24872      493 SWDEKALELLLAMEKVNPSrrhkrnmtsvvddvekdgaqtaeTKTAPESQAA--------TSARSFNVSDDLTQVAEVMM 564 
EDO48350      519 LMDTKTLELMAALEPFFSS-----------------------TPKPKKAAVTtqdesdshTQGKGGSHVDDLMKLADTLH 575 
XP_023605588  524 KKAEKDLTLLFAMEPLVNIkrnkglvfp------lenykegqAAY-YVKKNAfp-----dTYMKNSGFSDDVFHLGAALY 591 
Q96N23        521 KKAEKDLTLLIAMEPLINVkrnkglifp------lenykegqSTQIYLKKIAvh-----dTCLKTCGYSEDIFHLAATLY 589  human
Q8C6S9        526 KKAEKDLILLLAVEPLINVkrnrglifp------letdketqSIENYLKHIAch-----eSCMRTT-FTEDTFSLAAILH 593  house mouse
3_pfamImport  423 EKEKLELALLVSFNRLLSSqrshp--------------rqdnTIDGSYDEIVlyfmyppdTQKSSFSMGDEFIDLVDNLH 488 
XP_015207521  476 FKEELDLKLLVAMEPLITGqkykyttk--------esnvvgeGGQ--ERD----------KSSGPVVMSDDLLALAETLY 535  spotted gar
XP_008109087  489 KKAESELKLLIVMQPLLSTrkprhglsl-----rgsniqeafVVRSS-GKKLiafqegkpHV---GKTTDDLFSLARTLY 559  green anole
EKC24872      565 TIVNGPFVPS--KIEVDMVVDAALFLWSKAKSMFQKHQSGSSENPKYLQKM 613 
EDO48350      576 SCSVEPYKSIvgHMDPDMVIDAALFLWSKCKIHFQRVVSSSMEGCKFVLND 626 
XP_023605588  592 SCVCNSSQNV--QPDKEIVVDMIMFLWQKCKLGIQRLNISRLDYSKFTQKI 640 
Q96N23        590 VCVCTAPQDV--QPDKEIVVDTIMFLWQKCKLGIQRLNISRNDYAKFTQKI 638  human
Q8C6S9        594 FCVCVPTQGV--LPDKDIVVDIIGLLWQRCKLGIQRLNIPKNDFAKYSHKI 642  house mouse
3_pfamImport  489 KSVCVSALEV--QSDEDLVLDVVLFLWGEVKLVIPRDQLQNLQFTHYHEKV 537 
XP_015207521  536 TCVCVQAKGM--APDLDLTLDIVLFLWMKCKTVFQRVQTGHSDPIRSLYKL 584  spotted gar
XP_008109087  560 ACVCMSEKVH--LPDKEMIIDATMFLWQKCKLGIQKIQISGSNFLKCPQKY 608  green anole
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap