Conserved Protein Domain Family
Kre28
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pfam17097: Kre28 
Spindle pole body component
In Saccharomyces cerevisae Kre28 and Spc105 form a kinetochore microtubule binding complex, which bridges between centromeric heterochromatin and kinetochore MAPs (microtubule associated protein, such as Bim1, Bik1 and SIk19) and motors (Cin8, Kar3). It may be regulated by sumoylation.
Links
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Statistics
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PSSM-Id: 407241
Aligned: 5 rows
Threshold Bit Score: 390.321
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
A7TFD7   1 M---ETQAVKTIRDELRELENTVAQASDMVLSEQDHRNASAIREMTQSVIAMSKEN-SLIS-VSneidyneeiGNLAIDP 75  Vanderwaltozyma polys...
C5DK07   1 Ma--DDPTINGLELQLNAAEEHATALTEEALQNQDLHYKEVVEQLKRSVEQLVEDNeSLFTaVD---------LPPEVDP 69  Lachancea thermotoler...
Q751U7   1 MstkDTSGQSGYANDIRKLGEQTAHVSEQVLVQQERQRLGALEELHQSIIQIAEEN-SFVTpIKkd------aANVHIDP 73  Eremothecium gossypii...
Q6FSC7   1 M-----------EAQLHELQEEITRSSDLVLTEQDKRLQGTLREIDQSIRKLIETS-DYLK-LSg-------dADSLIDI 60  [Candida] glabrata CB...
C5DZ48   1 M----KSDLDGYEVRIKSLENQTAHYSEQALLEQEQRVLASLREITQNVIAMGQEN-SLVE-IKgele-skeeSELVIDP 73  Zygosaccharomyces rou...

A7TFD7  76 SLIDEKIKQSNNFVELLKLTHLEQEALDYFLRYTISSTN-TLELESTSDPKFVSLENEVTELENKTLTEHRDKIQEAKKD 154 Vanderwaltozyma polys...
C5DK07  70 TCISGRILDLAQLTQQLKSTHLQQETLDNFLRYTISSTD-ILQLESESDERYASVSRAVSQLQDNDIIQLDSEVDQIKQD 148 Lachancea thermotoler...
Q751U7  74 RGIAVSVQQFKQLAEVLKVTHLEQETLDNFLRYTISDNDqLLDIKSVADSRYARLAEEVCQLEQEELRHLENEIISLNGN 153 Eremothecium gossypii...
Q6FSC7  61 KQLEVKSRELDSLMDLLRKLYWREESLDLFLKYTINSDAeQVPVFSDTDPKYQSLQDEVSHLRDDVMTVKNQEIDQITGE 140 [Candida] glabrata CB...
C5DZ48  74 SGFQEKIDTFVELVELLKVTHLEQETLDNFLRYTISSSN-LLQINSVQDAKYVELESQVKELEQGTLESHKREIEATKGQ 152 Zygosaccharomyces rou...

A7TFD7 155 ISDKSKDLANKQDQINELCLGAANSVDECWKMLNELEDIHSqRDNDVKETLSQDTTt-TSDLIEETYKEWSSLQTSLTEL 233 Vanderwaltozyma polys...
C5DK07 149 IRKAGQTIADQREALNELCLETGNLADECHTLLSELEEATR-TREMVEKQAAVEVT--NDHPVEEMYASWQSLKEELQQE 225 Lachancea thermotoler...
Q751U7 154 ITEQTTKVIDANEKVKEECLEVSNGIERCWGLLNELETLR---------STTDEGNv-ELGPLEETYQKWKSVDHFLQQK 223 Eremothecium gossypii...
Q6FSC7 141 ILQVAHEITEKQDQVNMLYLETTNELDKCWELLDEWQRLQDdQRITKNEDNSNRKDt-ELNAMEECYEEWKTL------- 212 [Candida] glabrata CB...
C5DZ48 153 IKNLCQELSMAQDSINETFLDTSNALEECDALLNELTQLR------MEKQTSEEADtiEDDPVSQTYEDWESLQKSKLEL 226 Zygosaccharomyces rou...

A7TFD7 234 NNSKDELDQLIAFKNEKHKDNDSTKIRNANikNKTITENVKMLKLLINFWESNFIvpgskKSKLSNLEVYPQTKKFQFKC 313 Vanderwaltozyma polys...
C5DK07 226 SHLRRHLNQLKQSKASLEAILGTKNGNEHK--DTNVMQEYASYDAFIRFWISKFT-----NKEMENLEVFPRSNKFQFTH 298 Lachancea thermotoler...
Q751U7 224 LHLKEQLRVLEDTRKSLSEVTKSSGNRAP---DLDASEKFVTYRLLDSMWKKQFVd----TTKIRDLELYPRTGKIQFQV 296 Eremothecium gossypii...
Q6FSC7 213 EELAVLNDNLQKQIDELEKVDNKAINSTQL--AEESIVNTVQLNDLIDMWKRRIIas--iHEDISEIVLYPYSRKLQLRV 288 [Candida] glabrata CB...
C5DZ48 227 RLLEEETSRLQSRVESYEDYQKRSRQLSNN--DPRMLQNHKALELLVELWMTKFLp----QPGISHLELFPQSRKFQFDV 300 Zygosaccharomyces rou...

A7TFD7 314 AE-QYTVIIQln-----qnGGSIKSIEIFENDGK--SVQEnknLSSLILNKYknpLSSYPIFQVINDIVEEL 377 Vanderwaltozyma polyspora DSM...
C5DK07 299 RGtDVVISLG---------PRGISRVELYGKGIPleKIAA---ARKDVNEEA---SRGEELYMSINRIIDKI 355 Lachancea thermotolerans CBS ...
Q751U7 297 ADtIYVLAIS---------GDQISNIQLFNDKLPaaDLENn---TQDLNKRF---LGTSDVRRVVDFITHQq 353 Eremothecium gossypii ATCC 10895
Q6FSC7 289 AN-RYTIIIQldkhqthdgKSTIHDIDLFTEQDS--RIIPmreLRKQVLQEC---KGHSNILQALKNIINRV 354 [Candida] glabrata CBS 138
C5DZ48 301 EP-TFTVVITla------dQTTFQNVQVYRKDAK--SLVMdhgLNDEIKNSY---LGTNNIYNGLNDIIHTL 360 Zygosaccharomyces rouxii CBS 732
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