Conserved Protein Domain Family
PRK08418

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PRK08418: PRK08418 
metal-dependent hydrolase
Statistics
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PSSM-Id: 181419
Aligned: 29 rows
Threshold Bit Score: 534.934
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
32267263    2 LHIWGAQEAFICDENFSILHNGAIAFEenkDKILAVGDYEALCSQFPNAK-THFFPQGILLPSLINAHIHFEFGSHLAQF 80 
34557817    2 IHILGAERVLLCDEEFRLLSKGAVAFLg--DKILAVDSYEKLQKRYPEAL-AEYHPQGILLPGLINAHLHLEFSANQTTL 78 
157736750  20 MKAISASYVVTCDENNRIIKDGAVVFD---DKLIEIDTLFEIKNKYPNLEiKELEENSILMPGLVNSHIHLEFSANTTTL 96 
152992630   1 MKIIVADHIYTPN---GFIENQAVAFD---EQIRGIGPLESLLTIYPNADiIRTAPYSVIYPGFINTHVHLEFSANKTSL 74 
152990178   1 MRIIKPFAILTPQ---TIIQDKAVAFD---KKIEAIDTVENLIKKYPNAA-VEHDENSLLLPGFANPHLHLEFSANKATL 73 
154147920   1 MKILLAKYILTCDENFTILHDKAVVFD---DKIIEICDFKNAVKKYGNEAeILDYRNDFLMPAFINPHVHLEFSANRTTL 77 
118475030   1 MKIIKAKYILTCNDNFDILEDSAIAFD---EHIKQISSFDNLIKIYPDAQ-IMDFKDDIAMPAFINPHVHLEFSSNVSSL 76 
78776885    1 MQIITPEYILTPQ---NLLRNFSVAFD---KTIHKIAPLEELKILFPDAKiIKLQKNSLLMPGLINAHVHVEFSANKTEL 74 
291277639   1 MQVIGASKIFLCDEKFHILENGGIAFEk--GKIKDLGDYQKLCMQYGGGE---FFENSVLLPTFTNPHIHFEFSANHANF 75 
296272292   1 MKILKASWLICVDENSTIIKDGAILFD---EKIKDFGEIESLKAKYKDLEvEDLGVNTVLMPGLINSHIHLEFSSNSTSL 77 
32267263   81 CYGDFGAWLDSLMTSRDEVLNSGNSSetIILQDINDQINAGVGSVGAISSYGNDMTALASSPLRVVYFNEAIGSNPSAID 160
34557817   79 LYGGFDRWLSSVITHRDVLMGEGAKE--AMRRALDEVLSSGTTTIGAISSAGLDLEILAHSSLRVLFFNEVIGSNPSAID 156
157736750  97 KYGNFYSWLNSVIKHREDLINKATNE--LISTKLNKIKKTGTTTIGAISSYSFDMEACIKSPINTVFFCEVIGSKADMVD 174
152992630  75 KYGSFMPWLDSVIEHRDDLVNACDNA--MMQKECDEMLRSGITAFGAISSFGTELEVCEKAAQRVVFFNEVIGSNAATAD 152
152990178  74 QYGDFIPWLYSVIRHREDLLPLCDGA--CLEQTLSSIIQTGTTAIGAISSYGEDLQACIDSALKVVYFNEVIGSNAATAD 151
154147920  78 EYGDFLKWLKSVINSRDELSKEAKNA--AIKKQIEILKKSGVGTIGEISSFGIDTEICANSGIRTIFFNEILGSNPNFIN 155
118475030  77 DYGDFIVWLKSVIKTRDNLSEQAKNK--IIKNAITTMLKSGISTIGEISSFGNEAEICADSGARFIFFNEILGSNSENLS 154
78776885   75 SYGDFIPWLYSVLENRETLIEGCKKG--CMREAISCMLESGITTFGAISSHGMDLDVCADAKQNVVFFNELIGSQATMAD 152
291277639  76 LYGSFDKWLDSVMQKREDVLNDNTKA---IKEAIGQQLDSGVGSVGAISSYGDDMEILASCPLKVVFFHEALGSNAAALD 152
296272292  78 SYGNFMSWLNSVIINREALIEKSSTT--LINTKLNEMLKGGTTTIGAISSYGFEIEACTKTPINTVLFSEVIGSKADMID 155
32267263  161 FLYAHILERLERAKSL-HSPTFIPAIALHSPYSLHPIMAQKLIDIATKDKLPLSAHFLESAHEREWLTQNSGYFKTFFQR 239
34557817  157 FLWEDFLGRLKRSEEF-KSSRFTPLVAIHSPYSVHPFLIKRALLEAKRLGGVVSTHFMESKEEREWLEESRGFFGDFFAR 235
157736750 175 TLFADFRSRLNNAKKF-ASKNFIPAIAIHSPYSVHPFLVREALNVARDENLAVSSHFLESQEEFEWLHKDEGSFLEFFKN 253
152992630 153 MLYGDFLERVKASQSCdESAKITPAVAIHSPYSVHPIILQKAVTLAKQNKMPLTAHFLESQVERQWLEEGEGEFKSFFEK 232
152990178 152 VMYASFLERFHQSKKH-ENERFKAAVAIHSPYSVHYILAKRALDIAKKYGSLVSVHFMESRAEREWLDKGSGEFAKFFKE 230
154147920 156 QSWEKFLTRFEYSKNF-TNDMFIPAISVHSPYSTAEILTKKACDFARKNNLLMSTHFLESGYEREWLDGGNNDFKKYLLK 234
118475030 155 DNWDKFITKFNNSLKF-KSDKFIPAVSIHSPYSTHPKLAKRVLDLARQNNLLVSTHFLESEHEKRWLENGDGEFKIWLGN 233
78776885  153 ALFADFLARLDASKSV-NREGFYPAIAIHSPYSVHPILIKKALQIVKNENLKLTAHFMESSAEREWLDKSEGDFKEFFEK 231
291277639 153 FLHQNFLQRLEHSKAL-QSESFFPGIALHSPYSVHFVFAKKLLELARKENYPTSVHFLESSIEREWLEHSSGWFLEFFKK 231
296272292 156 TLFTDFKARLESAKKS-ASKSFIPAIAIHSPYSVHPFLVRESLRLAKEENLNVSAHFLESIEEFDWLHKDEGKFLEFFKN 234
32267263  240 FFKIENPqsFYSPQSFLDMLSPLrdtPLS-LTHCLYIKEEEAKMIESLQASIITCPRSNRLLNNAFFTRSLLRNKKIPLA 318
34557817  236 FFGGVKPkaLSTPLEFLELLEGQ---RVM-LVHGVQMNEEELAKAASLGASLASCPRSNRLLGGELLDISKVKKAGIPFL 311
157736750 254 FLNQEKA--TSKPMEFLGLFSKV---KNLsFTHCVEASDDDLEKIKDLGASINHCVTSNRLLNNTKLDLDRL--KDIPFT 326
152992630 233 YFSTSTP--VTNIQEFMHAFDTY---PTH-FAHAVQATEEELEYLSQKGHSIAHCPRSNRYLGCGRLPIETLQKYALPYS 306
152990178 231 FLNQTRP--VNDTKSFLELFKEL---HTL-FVHMVWANEEEIQTIASYNAHIIHCPISNRLLGNGVLDLEKI--KSIPYA 302
154147920 235 FSENPKP--FYTPKSFIEHFKEL---RTL-FTHCVFVDD--FSVFDVKFHAITHCAVSNRFLSAKTLDLNKIRASNINYN 306
118475030 234 FSKDVKP--FYTPKSFLNYFDGI---RTL-FTHCVFADEY-FEYFDKNLHCITTCPVSNRLLSNK-LNLKKVFDSNISLN 305
78776885  232 LLKQNSA--TCGASEFLEHFNEQ---QTL-FTHVVKANEEELLSIKKGNHTIIHCPISNRLLGNGALDLNEINKKNINWI 305
291277639 232 TLQVKNPrsLYEIEEFIELFLGL---DTL-FVHCLHATESEISKLTQ-TGYIITCPRSNRLLNNKLFPLQQAPIHKILF- 305
296272292 235 FLGQEKS--ATKPMEFLQQFSGI---KNLsFTHCVEASDNDLEKIKELGAVINHCPTSNRVLNNKRLEIEKL--KDITYA 307
32267263  319 LGTDGKSSNNNVNLLDELRTSLYAYPQEDILALAKSLILSATLYGAKTLGLNNGTLSEGKNVDFAIFEFsQplfqtHQSH 398
34557817  312 LATDGLSSNTSLSLLEELRIALFAYAKEPLESWARELVLSVTKRAAYALGLESGELREGLKADLALFEL-E-----GIGE 385
157736750 327 IGTDGLSSNNSLSMFDELRNALMAHYDKNVVEFSKILLKAATFNGSRALGLNKGVLKESFDADMISFKLpN-----KIED 401
152992630 307 VATDGLSSNDSLSIFDEFRAAIMLHHQAPIHILAERLIRASTQDAAEILGLNCGKIEVGALADLVVLTLpA-----MPQS 381
152990178 303 IATDGLSSNYSLNMYEELKAALFVHPNKEATTFAKELIIRATKAGYDALGFEGGEIAVGKDADMQLIDLpE-----GLTN 377
154147920 307 IATDGLSSNISLNFLDELRANLFIHDNENLCDFARELLQNSTSETAKFLGLDLGEISIGKIADFSIFNG-F-----EVSD 380
118475030 306 IATDGLSSNISLNFFDELRAALFTHSDFDLLELSKILLFSSTNAVAKSLGLELGVIKSGKIADISIIKG-I-----SVNS 379
78776885  306 CATDGLSSNYKLDLFEEMKCALFMHSNMPLLPLAKQLISSVTKDAALALGINSGEIEEGKNADMLVLDLdK-----EPN- 379
291277639 306 -ATDGKSSNNNLNFLEELRTALFAYANEDLENLAKNLLLSATRYGAESLRLNSGSLCKGLDADFSIFEIe------QITQ 378
296272292 308 IGTDGLSSNNSLQMFDELRNALMIHTNLNINELSVDLIKAATLNGAKALGLNKGRIKQGCDADIIVCKLpD-----EVKN 382
32267263  399 PNQSPLHFILHATKPTHLFINAKAVL 424
34557817  386 CTQEALQWILHAKKVKTLYIEGKKVE 411
157736750 402 INDICMQIILHTKFVDDVIIGGE-YV 426
152992630 382 KEEVALWSIIHTKQVSQVYIEGEQYV 407
152990178 378 VEDLYLHVILHTTKPKKVYIQGEEHV 403
154147920 381 ENQIALQIILQNKNVKKLFIKGKLCE 406
118475030 380 KEQLVLEILLHTKFVKKLYIKGNECL 405
78776885  380 -DELAIHLILHRYNISQIYINGKLIP 404
291277639 379 SKQAPLQFLLQAQKAKALFINGKKIL 404
296272292 383 EEELCTQIILHTKEVQNVYINGEKHV 408
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