2ZZK,1RJE,3IEI,6ID6


Conserved Protein Domain Family
LCM

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pfam04072: LCM 
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Leucine carboxyl methyltransferase
Family of leucine carboxyl methyltransferases EC:2.1.1.-. This family may need divides a the full alignment contains a significantly shorter mouse sequence.
Statistics
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PSSM-Id: 427692
Aligned: 98 rows
Threshold Bit Score: 91.5243
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2ZZK_A          6 TIKQTNKNVKQERR-KkyaDLAIQGTNNSSIASKRSVELlylpklssannfqMDKNNKlleYFKfFv-----PKKIKRSP 79  baker's yeast
jgi:Bphy_3713  13 AVRVALWRAMHVQV-Da-aPHVLDDEIGLRLAAPDAGWR--------------DRPDMdarG----------------TR 60 
Q63KM8         13 AVRVALWRALHARI-Da-pPHVLDDEIGLALAAPDDDW----------------RSRPdmdPQA--------------SR 60  Burkholderia p...
Q2IQA5         13 AVRVALWRALHVLA-Dp-pPHVLEDTVGLALAGPEEGWQ--------------QRPDMg-aF----------------TR 59  Anaeromyxobact...
XP_001302043   13 AVRTALWRGLHGLI-Da-kPLVIEDSVGLQLANPQEGWQ--------------ERPDMk------------------fTK 58 
jgi:Hhal_0188  10 AEIAAALRVWHTRL-Dd-aPTIFDDRAVLPLLSPRMR------------------QLVqppPPLlAmqlrtmEGMHPELA 69 
P46554         30 SVQRTNDDATQCKYfAt-qKGYWKDEFISRFANSSs-----------------------------------nVSEARRFP 73  Caenorhabditis...
1RJE_C          4 IIQQTDYDALSCKLaAi-sVGYLPSSGLQRLSVDLSKKYte----------wHRSYLItlkKFSrRafgkvdKAMRSSFP 72  baker's yeast
3IEI_E         25 GVRGTCEDASLCKRfAv-sIGYWHDPYIQHFVRLS---------------------------------------KERKAP 64  human
NP_001004645   16 AVRATCDDASICKR-FatsKGYWTDLYVQYFVRQIg------------------------------------ER---KAP 55 
2ZZK_A         80 CINRGYWLRLFAIRSRLNSIIeqTPQdkkI-VVVNLGCGYDPLPFQLLDTNniqsqqyhdRVSFIDIDYSDLLKIKIELI 158 baker's yeast
jgi:Bphy_3713  61 GYRASIVGRARFIEDLVAQQRd--RG---VeQYVILGAGLDTFAQRQPELAs--------RLTVFEVDRPGAATWKRQRL 127
Q63KM8         61 GYRASIVGRARFVEDLVDEQA--DRG---VaQYVVLGAGLDTFAQRRAKLAs--------HLRVFEIDQPGTQAWKRQRL 127 Burkholderia p...
Q2IQA5         60 PFRASIVARARFVEDLVEAQVa--GG---VaQYVVLGAGLDTFALRRPELGa--------RLRVFEVDEPATQAWKQRRL 126 Anaeromyxobact...
XP_001302043   59 PVRGAMVGRARLLDDYAIECSk--KG---IhQYVSLGAGLDTLAQRLGDSl---------NMQIFEIDEEPTLTWKEGRL 124
jgi:Hhal_0188  70 ALRGQTVTRARFAEDALDAAV--DRG---HrQIVLLGAGLDTTALRRPDLLa--------RTTLLEVDQAPMQWWKRAHL 136
P46554         74 EISMGYWARTAAIEKYVRDFLneFDG---NaQVVSLGCGFDTLFWRLVSSGa-------kLVKYVEVDFSSVTSKKIRHI 143 Caenorhabditis...
1RJE_C         73 VMNYGTYLRTVGIDAAILEFLvaNEK---V-QVVNLGCGSDLRMLPLLQMFp--------HLAYVDIDYNESVELKNSIL 140 baker's yeast
3IEI_E         65 EINRGYFARVHGVSQLIKAFLrkTEC---HcQIVNLGAGMDTTFWRLKDEDl-------lSSKYFEVDFPMIVTRKLHSI 134 human
NP_001004645   56 EINRGYYGRVKGMNLLLDDFLkkTQC---DcQVVNLGAGLDTTFWRLKDENv-------mPKKFFEVDFPMIVARKIHNI 125
2ZZK_A        159 KTIPELSKiiglsedkdyvddsnvdflT--TPK-YlaRPCDLNd-SKMFSTLLNEcqLYD-PNVVKVFVAEVSLAYMKPE 233 baker's yeast
jgi:Bphy_3713 128 VELGYGVP-------------------D--WLR-L--VPVDFEagQSWWEQIAHA--GFD-ADAPAVIASTGVSMYLTRD 180
Q63KM8        128 IALGYGVP-------------------Q--WLR-L--VPVDFEtsGAWRAQLSAA--GFD-DSRPAVVSSTGVSMYLTRE 180 Burkholderia p...
Q2IQA5        127 GELGLGVP-------------------P--FLR-F--VPVDFErgDPWLARLAGA--GFD-AARPAVVASTGVSMYLTRE 179 Anaeromyxobact...
XP_001302043  125 KELNLS-K-------------------A--YQH-F--VPVNFIk-SSWFDILKQS--SFK-SDQPSLLTCVGVTLYLDNN 175
jgi:Hhal_0188 137 PAKVA----------------------N--RMR-F--VAVDFAr-DRLAERLLDA--RID-PQTPLFANWMGCTYYLPPE 185
P46554        144 LKPIGPNSvdlkksfe---sdavvshhAdlHAGnYhlIGADLRqaNELDQKLATC--QLS-HDIPTIFIAECVLVYMSAD 217 Caenorhabditis...
1RJE_C        141 RESEILRIslglske------dtakspFliDQGrYklAACDLNdiTETTRLLDVC----TkREIPTIVISECLLCYMHNN 210 baker's yeast
3IEI_E        135 KCKPPLSSpilelhse----dtlqmdgHilDSKrYavIGADLRdlSELEEKLKKC--NMN-TQLPTLLIAECVLVYMTPE 207 human
NP_001004645  126 KTKPPLSKpliethstd-sllldghslD--SDR-YciIGADLRdiPTLEDKLKKF--QIN-PELPTLFLSECVLVYMSPE 198
2ZZK_A        234 RSDSIIEATS 243 baker's yeast
jgi:Bphy_3713 181 ANLATLRQIA 190
Q63KM8        181 AIAGTLSQIA 190 Burkholderia pseudomallei
Q2IQA5        180 AIASTLRAAA 189 Anaeromyxobacter dehalogenans 2CP-C
XP_001302043  176 AVHELLKNSA 185
jgi:Hhal_0188 186 AIGATLQGLA 195
P46554        218 SSTALLKQIV 227 Caenorhabditis elegans
1RJE_C        211 ESQLLINTIM 220 baker's yeast
3IEI_E        208 QSANLLKWAA 217 human
NP_001004645  199 QSSRLVHWIA 208
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