Conserved Protein Domain Family
FAM217

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pfam15344: FAM217 
FAM217 family
This family of proteins is found in eukaryotes. Proteins in this family are typically between 329 and 507 amino acids in length. There is a conserved YPDFLP sequence motif.
Statistics
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PSSM-Id: 464662
Aligned: 24 rows
Threshold Bit Score: 204.57
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015220394 190 SDLSDSERL-PVLPSPCTPPQLHLRAEVVDPSDLHPYFPGARG--GGSPGYSYPDFLPPPFSSWSLRQLALFLNTEGKGA 266
Q5XHY8       114 SDLSESEKMnDSLLSYFKKMDLNLKPETIEHVERAFTEEANQV-------SVYADFLPAPFNTMDLHRFA-FSKCESWKT 185 Norway rat
XP_023618801 188 SDLSENEKAnDTLLSCFKKMDLNLKPETIENVEEPFTEEPSEV-------FPYPDFLPPPFNTLDLHKLA-LSKSENWKA 259
XP_008272490 365 SDLSENEKAnDTLLSYFKKMDLKLKPETIESIEESFPEEPNEA-------FPYPDFLPAPFNALDLHKLA-LSKSENWKA 436
ELW48091     254 SDLSENEKAnDTLLSYFKRMDLNLKPETIDNVEESFTEEPNEV-------FPYPDFLPPPFSALDLHKLA-LSKSEAWKA 325
XP_005172823 145 SDISDSERY-SVLPAKISPPDLDLRAEVIDGSDPLHSFKPTNRvqRS----SFPDFLPPPFNSWSLTQLAVYLNTDGKTI 219
XP_014330137 160 tDLSESERL-PLSSRPLAP-RLELRPEVVEDGDAPSHCRTVRG-------RDFPDFLPPPFNSWSLSQLAVFYNTEGRGA 230
XP_008108351 215 SDLSDSERI-PIPPSPCTPPELNLRAEEIDPLHF--EHLFDAK--SKRLDYYYPDFLPPPYNTWDLKDLSLFVNTECKSE 289
XP_010720740 148 SDLSDSERI-PIPPSPCTPPELILRAEEIDPVCL--ERVPDTG--FKESEYYYPDFLPPPFNSWDLKQLAIFVNVEGRSE 222 turkey
XP_005993643 211 SDLSDSERI-ALHPSPCTPPELNLRAEEIDPVYL--VNVSDQE--FTKSEFYYPDFLPPPFNSWDLQQLAIFLNTEGKHA 285 coelacanth
XP_015220394 267 PRPKPVGQLERYLERLLQLEWLQIQTVQAEgsk-spSLVsAARPRPH--TAPPA----HLSSPKSLRQCQRAFpLAflSC 339
Q5XHY8       186 TVDPPESSIERLIMRLLELERLQHMTIQRE--------------RPKlqSTFCSsmfsMAERPSSSKAITLKArPPkiPE 251 Norway rat
XP_023618801 260 TVESPESCIEPLITRLLEMERLQHTTIQKE--------------RPRlqTTFCTp--aVSERPFSSKTIP-KMrQPklSD 322
XP_008272490 437 TVDAAESSVELLIARLLELERLQHTTIQKE------------KPRLQ--TPFCAp--aLTERPSSSKAAP-KGkQSkvSD 499
ELW48091     326 TVEPPESTIEHLVTRLLELERLQHATIQKE--------------RPKpqTTLCTp--aVTERPSSSKAIS-KVkQPkfPD 388
XP_005172823 220 PRPKPVGQLERYLDRLLQMEWHQIQTLQED------SSKsAPKHRHP---TPHS----SLSAPKCILQCQRAFpLGllSS 286
XP_014330137 231 FRPRPTGPLERYLERLLQLEWHQIQTVQAEhgtqdiPGGtSSCQRSSaaTPAPT----RLSSPKCILQCQRAFpLSflSS 306
XP_008108351 290 PKVPAVGFLDKYIDRLLELEWLQIQTVQAE------QGK-ASKSRPQ--TAPGMl--rTLKSPGKIKSLHSPSrNKqlIP 358
XP_010720740 223 LRPKPTGFLEKYIDRLLQLEWLQMQTVQNE------KAK-AAKARPQ--TAPSSv--rTLKSPGKCKALLSPLpHKqmVS 291 turkey
XP_005993643 286 TRPQPAGVFEKYVDRLLQMEWLQMQTIQSE------KER-ASRPRPQ--SAPSSf--rSPKSPGKSKPWQTPVpTRv-PS 353 coelacanth
XP_015220394 340 LG-------NPSAPQLS---------------RPACPHcRVHYPFcnga--craYAYQRHSRLSPLLERRagACGPQRRS 395
Q5XHY8       252 TP-------TLQTSSVDknr----------dkRKNNS-----------------------------------GSGKPEQN 279 Norway rat
XP_023618801 323 SV-------SLQTTCVDktr----------ekRKKNS-----------------------------------ASCKLEQN 350
XP_008272490 500 SL-------GFQASCAD---------------KSREK----------------------------RKNNS--GSYKPEQN 527
ELW48091     389 SS-------SLQTSCIDksr----------dkRKNSP-----------------------------------GSCKLEQN 416
XP_005172823 287 MT-------SL---------------------HLSCTHcHNHYST---------GSYRQHTRLHTEKRSS----GVPQRS 325
XP_014330137 307 LA-------GHAALLAG----------------GTSGLcRICSSScsasccrstHCHRHLSRLSPDGSRG--PLPRPKRS 361
XP_008108351 359 HE-------SLSRLPIShsv----------prRDPHAErTSQF-----------FPYEGHSRGA--TSSS---LAHQRRS 405
XP_010720740 292 QE-------TVTKLPTCysghrvdpcceesrqF---------------------YSHPGHLKQSERTGHA---ISSQRQS 340 turkey
XP_005993643 354 QGvakffrsSYSNCRVKypy----------csDKCNP-----------------YTYQIHSRLPTMMDSA---LPPQKRP 403 coelacanth
XP_015220394 396 SSesrVASSDprpgvQ-GQKPESPSPGAGHLKRMQAAGNIR 435
Q5XHY8       280 VPkwsLSTAGksksnSrS-LLKCSST---SKQCAMAHDDVK 316 Norway rat
XP_023618801 351 ASqwnWSSAGkykwnSrPPSLKSSST---TKQLVATYDDFK 388
XP_008272490 528 ASkwnWSNSGrykwdSrPPSLKSSPT---TKQLMATYDDSK 565
ELW48091     417 ASkwnWSNAEkskwnSrPPSLKSSPT---TKQFIATYDDLK 454
XP_005172823 326 SSesrTRSEPrh----rEHRLSDPLSESRHLRRMQAAGNIR 362
XP_014330137 362 YSesrVHSSDrrlrtQrSGSPSSSSS---YLRRMQASGNIR 399
XP_008108351 406 GE---VKSEAkkrptTkQQHLPRHPSD--TSSMIQGAGNMR 441
XP_010720740 341 GE---VRNELrk-ttAkQQLLNMQPSE--NNSKIQSVGNIR 375 turkey
XP_005993643 404 SSetrVKSKTrrsenLkQDVPSLQAHGRNSGCKVQSAGNIR 444 coelacanth
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