4U7J,2NZ2


Conserved Protein Domain Family
Arginosuc_synth

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pfam00764: Arginosuc_synth 
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Arginosuccinate synthase
This family contains a PP-loop motif.
Statistics
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PSSM-Id: 279148
Aligned: 13 rows
Threshold Bit Score: 627.452
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4U7J_A                   14 ILAYSGGLDTSVAISWIGKETg-REVVAVAIDLGQGgEDMEVVRQRALDCGAVESIVIDARDEFANDYCVPAIQSNALYM 92 
O34347                    8 VLAYSGGLDTSVAIKWLQEQG--YNVIACCLDVGEG-KDLAFVQQKALEVGATNSYVIDAKEEFAQDYALISLQAHTMYE 84  Baci...
PRJNA488350:D1794_24900  13 VLAYSGGLDTSVAIGWIAEETg-AEVIAVAVDVGQGgEDLDVIRKRALACGAVEAEVADAKDEFAEEYCLPAIKANARYM 91 
O85176                    6 VLAYSGGLDTTVAIPYLKKMId-GEVIAVSLDLGQGgENMDNVRQRALDAGAAESIVVDAKDEFAEEYCLPTIKANGMYM 84  Cory...
P9WPW7                    6 ILAYSGGLDTSVAISWIGKETg-REVVAVAIDLGQGgEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNALYM 84  Myco...
P77973                    8 VLAYSGGVDTSVCIPYLMHEWgvEEVITLAADLGQG-DELGPIQEKALRCGAVESLVIDGKEEFVKEYAFRSIQANALYE 86  Syne...
P14568                    8 VLAYSGGLDTSCILVWLKEQG--YDVIAYLANIGQK-EDFEEARKKALKLGAKKVFIEDISKEFVEEFIWPAIQSSALYE 84  cattle
O28032                    4 VLSYSGGLDTTVCIPLLKEKYgfDEVITVTVDIGQPeADIKQAEERGKKYAD-KHYTIDAKKEFV-DSLFMLIKANGNYE 81  Arch...
Q8TNY5                    6 aLAYSGGLDTSVCIPILKEKYgyDEVITISVDVGQPeEEIKKADAKAEKISN-KHYTIDAKEEFVKDYIFPLIKANGDYE 84  Meth...
O27322                   10 VLAFSGGLDTSVCIKLLEEKYn-mEVITACVDVGQPrDEIERPAMVAKELGNYRHYTVDARREFAEDYIFPAIKANAVYE 88  Meth...
Q60174                    6 VLAYSGGLDTSCCLKLLEDKYg-yKVVSVCVDVGQPeEEIKEVEEKAKKLGVLKHYTIDAKEEFVKDYIFRAIKANAMYE 84  Meth...
P22768                    7 CLAYSGGLDTSVILAWLLDQG--YEVVAFMANVGQE-EDFDAAKEKALKIGACKFVCVDCREDFVKDILFPAVQVNAVYE 83  Sacc...
2NZ2_A                    9 VLAYSGGLDTSCILVWLKEQg--YDVIAYLANIGQK-EDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYE 85 
4U7J_A                   93 DRYPLVSALSRPLIVKHLVKAAREHGGTIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWT-----REKAIAFA 167
O34347                   85 GKYPLVSALSRPLIAKKLVEIAEKEDAQAIAHGCTGKGNDQVRFEVSIKSLNPDLEVIAPVREWQWS-----REEEIEYA 159 Baci...
PRJNA488350:D1794_24900  92 DRYPLVSALSRPAIVKHLVAAAKKHDASIVAHGCTGKGNDQVRFEAGIQALGPDLKCIAPVRDYAMT-----RDKAIAFC 166
O85176                   85 KQYPLVSAISRPLIVKHLVEAGKQFNGTHVAHGCTGKGNDQVRFEVGFMDTDPNLEIIAPARDFAWT-----RDKAIAFA 159 Cory...
P9WPW7                   85 DRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWT-----REKAIAFA 159 Myco...
P77973                   87 NRYPLSTALARPLIAKMLVEAAEKYGADAVAHGCTGKGNDQVRFDISIMALNPNLKVLAPAREWKMS-----REETIAYG 161 Syne...
P14568                   85 DRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQIRFELTCYSLAPQIKVIAPWRMPEFYnrfqgRNDLMEYA 164 cattle
O28032                   82 G-YVLGTALARPLIAEKVVEVAKKEGAEAVAHGCTGKGNDQLRFENIFRQHG--FKVIAPVRELNLT-----REWEIEYA 153 Arch...
Q8TNY5                   85 G-YVMGTSVARPLIAKKVVEAAIKEGAVALAHGCTGKGNDQLRFEAVFRQTD--MDVIAPMREMNLT-----REWEIDYA 156 Meth...
O27322                   89 G-YPLSTALARPLIAKKIVEVAEKEGASAIAHGCTGKGNDQFRFEAVIRSTT-DLDVIAPIRDLNLT-----RTEEMEYA 161 Meth...
Q60174                   85 G-YPLSTALARPLIAHKVVEIAEEVGAEAVAHGCTGKGNDQFRFETTIRIKAPHLKIIAPIRDLNLT-----RAEEIEYA 158 Meth...
P22768                   84 DVYLLGTSLARPVIAKAQIDVAKQEGCFAVSHGCTGKGNDQIRFELSFYALKPDVKCITPWRMPEFFerfagRKDLLDYA 163 Sacc...
2NZ2_A                   86 DRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEFYnrfkgRNDLMEYA 165
4U7J_A                  168 EENNIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYSYTEDPTVNWSTPDEVIVGFEQGVPVSI----D---- 239
O34347                  160 ASRGIPIPINLDSPYSIDQNLWGRANECGILEDPWAAPPEGAYDLTAPLEKTPDTPEVIEIAFEQGVPVSI----D---- 231 Baci...
PRJNA488350:D1794_24900 167 EAKQLPIATTKKSPYSIDQNVFGRAIETGFLEDIWNAPIEDIFEYTSNPAEPR-EADEVVISFASGVPVAI----D---- 237
O85176                  160 EENNVPIEQSVKSPFSIDQNVWGRAIETGYLEDLWNAPTKDIYAYTEDPALGN-APDEVIISFEGGKPVSI----D---- 230 Cory...
P9WPW7                  160 EENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSV----D---- 231 Myco...
P77973                  162 ERYGVESPVKKSSPYSIDRNILGRSIEAGPLEDPMTEPTEEIYLMTKAIADTPDEPEYVDIGFEKGIPVSL----N---- 233 Syne...
P14568                  165 KQHGIPVPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNSPDMLEIEFKKGVPVKV----Tnv-- 238 cattle
O28032                  154 RQHGIEVPATKEKPYSIDENLWSRSVEGGKLEDPSFEPPEDIYEWTASPEKAPDKPEIVKIDFEKGVPVAL----N---- 225 Arch...
Q8TNY5                  157 KEHGIPVEVTKAKPWSVDENIWSRSIEGGKLEDPSFVPPEEIFEWTKSAEDAPNEPRIVDIDFEAGVPVAL----D---- 228 Meth...
O27322                  162 RSCGIPLPSD--KLYSIDENLWGRAIEGDILEDPMVEPPEDAFEWTKPIHETPEDPEVIEIGFHGGVPVAL----N---- 231 Meth...
Q60174                  159 KEKGIPIPTESKK-YSIDENLWGRSIEGSELENPDFVPPEEIYAWTKNPVEDK-EEEIVEIEFKEGVPVAI----N---- 228 Meth...
P22768                  164 AQKGIPVAQTKAKPWSTDENQAHISYEAGILEDPDTTPPKDMWKLIVDPMDAPDQPQDLTIDFERGLPVKL----Tytdn 239 Sacc...
2NZ2_A                  166 KQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVtnvkD---- 241
4U7J_A                  240 --GRSVTP---LQAIEELNRRGGEQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRITDQK 314
O34347                  232 --GVSYSL---SELILKLNEMAGAHGVGRIDHVENRLVGIKSREVYECPGAMTLIKAHKELEDLTLVKEVAHFKPIIEQK 306 Baci...
PRJNA488350:D1794_24900 238 --GRPVTV---LQAIQQLNERAGAQGIGRIDMVEDRLVGIKSREVYEAPGAIALITAHQELENVTVERELARFKRQVEQR 312
O85176                  231 --GRPVSV---LQAIEELNRRAGAQGVGRLDMVEDRLVGIKSREIYEAPGAIALIKAHEALEDVTIERELARYKRGVDAR 305 Cory...
P9WPW7                  232 --GKPVSM---LAAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQR 306 Myco...
P77973                  234 --GVMLDP---VTLVERLNEIAGNHGVGRLDMVENRVVGIKSREIYEAPALLVLIDAHRDLESLTQTADVTHYKNTVEEI 308 Syne...
P14568                  239 gdGTTHSTa--LELFLYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLK 316 cattle
O28032                  226 --DERMGG---FELIKALNEIGGKHGVGRTDMIEDRVLGLKARENYEHPAATILITAHRDLENLVLSRRELKFKKFVEEE 300 Arch...
Q8TNY5                  229 --GEKLGG---YALVRKLNEIAGENGVGRTDMIEDRVLGLKARENYEHPAATVLLAAHADLEKLVLTRGELKFKKIVDEQ 303 Meth...
O27322                  232 --GEELEP---VELIGLANEVAGKHGIGRVDIMEDRIIGMKSREIYETPAAFLLLEAHRGLEQLTLTRSELRFADIISST 306 Meth...
Q60174                  229 --GEKLEP---VELIKKANEIAGKHGVGRIDIIEDRIIGLKSRENYECPGAVLLLTAHKALEQLVLTRDELRFKEIVDSL 303 Meth...
P22768                  240 ktSKEVSVtkpLDVFLAASNLARANGVGRIDIVEDRYINLKSRGCYEQAPLTVLRKAHVDLEGLTLDKEVRQLRDSFVTP 319 Sacc...
2NZ2_A                  242 --GTTHQTs--LELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLK 317
4U7J_A                  315 -WGELVYDGLWFSPLKTALESFVAKTQEHVTGEIRMVLHGGHIAVNGRRSPKS-LYDFNLATYDEGDTFDQSAAKGFVQI 392
O34347                  307 -MSEIIYNGLWFSPLKDALHAFLKETQKHVTGIVRVKLFKGHAIVEGRKSEYS-LYDEKLATYTKDDAFDHHAAIGFIEL 384 Baci...
PRJNA488350:D1794_24900 313 -WGELVYDGLWFSPLKRALDGFIEEANQQVTGDIRMTLHAGTAVVTGRRSERS-LYDFDLATYDTGDTFDQSKAQGFIDI 390
O85176                  306 -WAEEVYDGLWFGPLKRSLDAFIDSTQEHVTGDIRMVLHAGSITINGRRSSHS-LYDFNLATYDTGDTFDQTLAKGFVQL 383 Cory...
P9WPW7                  307 -WAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAES-LYDFNLATYDEGDSFDQSAARGFVYV 384 Myco...
P77973                  309 -YSQLIYRGLWYSPLKEALDAFIVKTQERVTGMVRVKFFKGNANVAGRKSDYS-IYDAELATYGMEDQFDHKAAEGFIYI 386 Syne...
P14568                  317 -FAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVFKGQVYILGRESPLS-LYNEELVSMNVQGDYEPVDATGFINI 394 cattle
O28032                  301 -WAELVYYGLVNDPLFDALNAFIDKTQERVTGWVKVKLYKGSAVVVARNSPYA-LYSEELVSFD-TESIDQRLAEGFAAF 377 Arch...
Q8TNY5                  304 -WSELAYYGLVDEPLYADLNAFIDKSQERVTGTVKVKLYKGALTILARSSPNA-LYSEDLVSFD-SQTIDQKDAEGFAKY 380 Meth...
O27322                  307 -YAELVYSGLWHDPLREDLDMAVNHMQRRVTGTVRVKLHRGSMRVIGRESPYS-LYSEEIVSFE-DKTLDQREMAGMVKN 383 Meth...
Q60174                  304 -YGELIYKGLWFDPLREDLDAFIDKTQERVTGTVKVKLFGGTARVVGRDSPYA-LYSKELVSFD-EKEIDQKELAGMVKY 380 Meth...
P22768                  320 nYSRLIYNGSYFTPECEYIRSMIQPSQNSVNGTVRVRLYKGNVIILGRSTKTEkLYDPTESSMDELTGFLPTDTTGFIAI 399 Sacc...
2NZ2_A                  318 -FAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLS-LYNEELVSMNVQGDYEPTDATGFINI 395
4U7J_A                  393 HGLSSSI 399
O34347                  385 WGLPTKV 391 Bacillus subtilis subsp. subtilis str. 168
PRJNA488350:D1794_24900 391 FALSAKI 397
O85176                  384 HGLSSKI 390 Corynebacterium glutamicum ATCC 13032
P9WPW7                  385 HGLSSKL 391 Mycobacterium tuberculosis H37Rv
P77973                  387 WGLPTKV 393 Synechocystis sp. PCC 6803 substr. Kazusa
P14568                  395 NSLRLKE 401 cattle
O28032                  378 HGLQGRL 384 Archaeoglobus fulgidus DSM 4304
Q8TNY5                  381 HGFQARM 387 Methanosarcina acetivorans C2A
O27322                  384 YALQAAI 390 Methanothermobacter thermautotrophicus str. Delta H
Q60174                  381 HGLQAML 387 Methanocaldococcus jannaschii DSM 2661
P22768                  400 QAIRIKK 406 Saccharomyces cerevisiae S288C
2NZ2_A                  396 NSLRLKE 402
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