Conserved Protein Domain Family
Caps_synth

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pfam05704: Caps_synth 
Capsular polysaccharide synthesis protein
This family consists of several capsular polysaccharide proteins. Capsular polysaccharide (CPS) is a major virulence factor in Streptococcus pneumoniae.
Statistics
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PSSM-Id: 368570
Aligned: 28 rows
Threshold Bit Score: 211.367
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012661946  27 Ir--rKLRNHIQYKLEHPKVASYLSNNYINPFLDGKIPHFDFEKKHHFKNDKI-------IWQFWYQGK-DQA-SPMIQQ 95  Campylobacter lari
Q4K038        46 R-----------------LNNSNIVLSRLRRNYRSAIQKFREENQYSLVYDQQdsstsskIWICWFQGL-DVA-PHVVRE 106 Streptococcus p...
Q4JZR5        46 R-----------------LNNSNVVLSKLRRKYKQTIKNLDREKQYSLSYNQRhkdasnkIWICWFQGL-DTA-PHVVQE 106 Streptococcus p...
Q1WRW7        21 Ki---GIYTYVYPLKLSKKEKELIWRNTVKKDIKKSICFFNDEIIQEPMRQKY-------IFICWLQGI-EKA-PYIVQQ 88  Lactobacillus s...
WP_011960254  50 R-----KAFEKEADLEQQNQVAKCWAEFIKRYYSGQLQKFSLKPKKEFQNEKI-------IWQYWGQGVsDNQlPPSVQL 117 Psychrobacter s...
Q8A3T2        19 R--------RKASIIRQQGKVADFWAPILKAYYNGEIERYSLKPKKKLGTQKV-------IWQYWGQGIdKDElPEIIQI 83  Bacteroides the...
Q9ALT3        21 Hr--rIIKGKILHQKEHENIANYLENAYIKKYFENKLDDIQIKKTRNINGKKI-------IWQFWYQGI-DNA-PCIIKK 89  Campylobacter j...
Q0AKZ7         1 M--------------------------------------FAVSRTRRPQMNKT-------IWMLWLQGR-ENA-PAVVQR 33  Maricaulis mari...
Q4JYV2        19 Ra--iNDVLPVNLIFPSQQLRRLNWQEKVKKKLKKYVVISDSIKSEEECDI---------IWWLWFQGL-DNA-PAIVKK 85  Streptococcus p...
Q2ERD8       320 KnpniNWNLFFDSNNPGLSYRRDELKFILENLSDIQRIADSYPSSHINFKESP-------VFVFWDQGY-DNA-PIIVKS 390 Haemophilus inf...
WP_012661946  96 CFNSIQNQMk-DDYTIIILDKDNIKDYLVFPSFVIEKLENNFFgekTITFFSDLLRVCLLATYGGIWCDASIFLS-SKIP 173 Campylobacter lari
Q4K038       107 CIASVRKQL--ADREVVVLTDDNYHHYVTFPDHIKAKIDQGII---SKTHLSDLLRLELLTKYGGTWIDGTVFCSsSDIP 181 Streptococcus p...
Q4JZR5       107 CIASVKKHL--ADREVVVLTDENYHQYVTFPDYIKEKATQGFI---SKAHFADLLRLELLTEYGGTWIDGTIFCSsSDIP 181 Streptococcus p...
Q1WRW7        89 CVASVKKNS--GDFKVIIIDGNNYKEWVDIPDFLIKRWQEGKM---LDAWFSDILRLFLLCKYGGLWIDATVYMF-DKVP 162 Lactobacillus s...
WP_011960254 118 YFKSVDKHA--ADYKVIRLDDSNIHEYLDLPDFVWHKKTYPGF---RPAFFADLLRLALLDVYGGVWLDATIYLT-APLP 191 Psychrobacter s...
Q8A3T2        84 CFDSVDRNK--NDYQVIRLTDITISEYIDLPDFVWRKREYVQF---TRTFFSDLLRVALLSTYGGVWLDATILLT-GSIP 157 Bacteroides the...
Q9ALT3        90 CFKSVQKYK--GNYEVVLLDKDNIKDYLIFPDFIYQKIDDKKFgekTITIFSDLLRVSLLNNYGGIWLDAGMFLS-GEIQ 166 Campylobacter j...
Q0AKZ7        34 CIHSWEVNN--PTWTLKLLTADTVSHYIDVTEFV--DLQTQTL---QAASLSDIIRIMLLHEYGGVWADATTLCN-APLD 105 Maricaulis mari...
Q4JYV2        86 CRESVDKYAkrSGKRVIELTSQNLFEYIEVPNELYVKYKSGSL---PLALFSDFCRISLLSNYGGLWIDSTVLIT-GEIE 161 Streptococcus p...
Q2ERD8       391 MIDRMKIIY---GNKLVFLTGETIEAYIDIPARIESFRES------KRAFFSDYIRTELLLRYGGTWIDSTVFTT-NQFY 460 Haemophilus inf...
WP_012661946 174 SELC------DKDFFTF--ERSKTKPSKEKLKKFiksgyfsygyfnwnddfkvkmLSSFMIAKTSNTFIQTLKDILMNYW 245 Campylobacter lari
Q4K038       182 VYML------DSDLFLFqnLKPGLDGQALAISTW-----------------------FMTAAKLHHPLLELTKDLLYLYW 232 Streptococcus p...
Q4JZR5       182 AYML------DSDLFLFqnLKPGLDGQALAISNW-----------------------FITASYSNHPLLNMTKDLLYDYW 232 Streptococcus p...
Q1WRW7       163 NYIV------ESNRFMF--QSSFLESETTHISNW-----------------------LIFVKSKNDPFLVGLKNSMVTYL 211 Lactobacillus s...
WP_011960254 192 NVLQ------DSGFFMY--QRAANAKDKQQWHKFnsyyfnwe------srhkvnlLNSIIFAHKNDPVIHTCLDLILNFW 257 Psychrobacter s...
Q8A3T2       158 AVYE------KTDFFMY--QRSDEEKNKKYWENVyayyfgwe------pnfkvrmLSSILFAQKESEIISTLTDLLLYFW 223 Bacteroides the...
Q9ALT3       167 KEIL------DQDFFIF--HRSTKKP--QDYKNWinfnynffs---wdekfkvniVNGFILSNKNNEIMKIMQDILINYW 233 Campylobacter j...
Q0AKZ7       106 DWLPev---sGTGFFAF--SLSPFPQGDRPLSSW------------------------FLAAEAGNSLVGKWAGRVHAYW 156 Maricaulis mari...
Q4JYV2       162 DEIL------NQDIFMF--QASPLDYSVTKISNW-----------------------MLYSKYPGHPFISSIRDTLISFY 210 Streptococcus p...
Q2ERD8       461 KENLeileknDNNLYVL-----RIPENPYRISNW-----------------------FLSTNQTGNRILALMYATMLIFA 512 Haemophilus inf...
WP_012661946 246 KNEQSSENhyYFVLHIIFELLKEHG-FVNDTYKN---MSDIEC--HLLQFYAKEKFDENLWKSIQKQ-S-FLHKLTH--- 314 Campylobacter lari
Q4K038       233 KKNNTMVD--YFLIHHFFQLSIE---EFPEYWSRvvpFNNSTP--HILQLRLFEEFDETMYRHILEQ-T-PFHKLTYkfe 303 Streptococcus p...
Q4JZR5       233 KNHNGVVD--YFIFHHFFQLSIE---EFPEYWSKvvpFNNSTP--HILQLRLFEEFDEVMYGYILEQ-T-PFHKLTYkfe 303 Streptococcus p...
Q1WRW7       212 KKKEKPAD--YYIFHDFVSVMAVSK-EYSKYWKEipyVNNVNP--HMLQYLGNLPYDNSMFNYIKST-S-PVQKLTYkld 284 Lactobacillus s...
WP_011960254 258 QTQEYIPH--YFFFQILFDTLIKEE-LAQ---YQcpiVDDTKP--HLLVAALYSPFNEAYFKKIISQ-A-SIHKMSY--- 324 Psychrobacter s...
Q8A3T2       224 KTQDSLPD--YFCFQILFNELVANY-RPA---ENcpiVNDCIP--HIIQTKINGTYDDVSFEEALEL-S-NIHKMTY--- 290 Bacteroides the...
Q9ALT3       234 KYENKLVY--YFMFQILFDTLKKK--YLN---LNlyiTNDTDI--HLLQYHAKDKYSDKLWNDIKNK-T-SIHSLKI--- 299 Campylobacter j...
Q0AKZ7       157 QNRESSDD--YFWFHHQFYELLEQDaLALQAWQKvprLSAAGP--HSVQFNFGGLDQDAESVANQIDwSiPLFKLTHrie 232 Maricaulis mari...
Q4JYV2       211 NKNNTIPD--YFLFHLLVSCLIDDN-RINQSFYDmdyYTNTYP--HLLGRVLSEPYDTLKFENILRK-T-SIHKLSYk-n 282 Streptococcus p...
Q2ERD8       513 EKRNSLFE--YYQYHTFFEILTQLDkQANEDFHKny-rNNYQPyaHDLLKNFRNDWDRELFNKLIAR-C-PIQKLTYksn 587 Haemophilus inf...
WP_012661946 315 FKSIKKds-miDKI 327 Campylobacter lari
Q4K038       304 GEKSSIpntyyKHL 317 Streptococcus pneumoniae
Q4JZR5       304 EEKSRIpntyyKHL 317 Streptococcus pneumoniae
Q1WRW7       285 YNNLKRnt-yyDHI 297 Lactobacillus salivarius UCC118
WP_011960254 325 VKEVKPgs-yyEYL 337 Psychrobacter sp. PRwf-1
Q8A3T2       291 FDAAam---irLKM 301 Bacteroides thetaiotaomicron
Q9ALT3       300 FKKIRKhs-miDKI 312 Campylobacter jejuni
Q0AKZ7       233 PRHLKAgt-ilTHV 245 Maricaulis maris MCS10
Q4JYV2       283 LDNVAEds-fyNAI 295 Streptococcus pneumoniae
Q2ERD8       588 LLHLRThs--llHL 599 Haemophilus influenzae
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