6KGJ


Conserved Protein Domain Family
Nt_Gln_amidase

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pfam09764: Nt_Gln_amidase 
N-terminal glutamine amidase
This protein is conserved from plants to humans. It represents a family of N terminal glutamine amidases. The enzyme removes the NH2 group from a Gln, at the N-terminal, rendering it a Glu.
Statistics
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PSSM-Id: 462887
Aligned: 45 rows
Threshold Bit Score: 199.74
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6KGJ_A        23 YSSCYSEENVWKLCEYIKNHDQYPLE----------ECYAVFISNERKMIPIWKQQA--RpGDGPVIWDYHVVLLHV--- 87 
EEC43125      98 YFAHYCEENVWRLAYRKMMQNEHNRN----------RYHVVFCTNRKKCLPMFYQTIt-RnNRIPCVWNYHCILLETn-- 164
EED93993      24 RVPFYCEENAWRVAFRHTHSSDNRKPsnee--edvwEYYVVFISNQLRCCPLFKQRAv--aPDEYVSWDYHVIVIRTmes 99 
XP_007843738  14 YTLFWCEENVYLLAQNFLRDAQIVSNw---------DLFAVFISNAAQTVALWNQKLa-QePGLPVVWDYHVILVLRlrl 83 
EKM83021      36 YTRCYCEENVYLLCEDFMNRKDVCERw---------NIWVVFISNETKTVALWDQKVa-RePGAPVLWDYHVILVLEpte 105
EDR10947      13 YTSCWCEENVYLLCQKFLADPSISKEw---------TPWVVFISNLTKTVALWNQKAa-RdKDSVVVWDYHVILILEhnv 82 
XP_004990422   9 YTRCYCEENVWKLLHDEAPRISAGDAynacnaaaavSWAACFISNPNKTVAVACQAAs-QdELGLVVWDYHVVAIGPd-- 85 
EPB87294      16 YTACYCEENIYMLCSEILKKRPELID----------DFSVLFISNPHRSVPLWQQRAg-RgDEHVVIWDYHVVLYy---- 80 
XP_001009551  24 YTRCYCEENVYKLCEKFEERVKAGELnkn-----dhAVFAVFITNQFRQTYIKQQLTgdSkNDYLVMWDYHVILVHKdlk 98 
A0C2P2         6 YTAYYCEENIYNLVQDMMEEKQDHLT----------QHYAVLITNPFQQTYIKCQKSs-----PLVVWDYHVIMVVKhty 70  Paramecium tetr...
6KGJ_A        88 ------------SsggqSFIYDLDTVLP-FPCLFD--------------------TYVEDAIK--SDDDiHPQ--FRRKF 130
EEC43125     165 ------------AtsteTVVFDMDSQLP-FPYPLD--------------------RYLDRTFPstMDYa-AED--LEPVF 208
EED93993     100 cs-----tssdgDnknaTEVLDVDSWLQ-YSCPIE--------------------EYLDGTFPhtTNEDlDPK--YMPMF 151
XP_007843738  84 ---------knpGdqpvAWVYDFDTILS-FPTSWT--------------------DYFGKTFSa----HvLPN--FQSSF 127
EKM83021     106 afkaansdckneSqtarSWVYDFDTLITpVPCTWLgepfdwwhctspndkdcdsiDYIARTFPrqENS----------MF 175
EDR10947      83 kd------tpnlSgdrkSWVYDFDTWLQ-MPYSFD--------------------DYWSGTFP--PDDLlPQD--LQSLF 131
XP_004990422  86 ------------PqtgqPSVFDLDTTLP-FPCPIE--------------------EYWHKAFLt---dWlPPR--LHPMF 127
EPB87294      81 ------------KqdseALIYDFDTFLP-FPSPAD--------------------FYALETFK--PNMViKDE--YKHMF 123
XP_001009551  99 --------------ankSYVYDFDSKLS-WGCKFE--------------------EYFIKSLL-----KkYPTsaLQTMY 138
A0C2P2        71 q--------qegKitqnSFVYDFDSTLP-MNCDFN--------------------TYFKQALG-----FqKPQatLKSWF 116 Paramecium tetr...
6KGJ_A       131 RVICADSYLKNFASDRSHMK-----------DsSGNWREPPPPYPCI-----ETGDS----------------KMNL-ND 177
EEC43125     209 RTVQASAYIENLSNDRSGKEf---------cDvANDWIAHSPTYKEI------GEVT----------------SANL-DQ 256
EED93993     152 RVIPTKQYLKYFYSDRMHMYg------------DGKWSRPPPSYAPImngleFASGEplttgdaasddcngvrASNL-DS 218
XP_007843738 128 RVIPANEYIDHFASDRSHMVhsfss-pqeseDaDPIYLKPPPPYPCIcgpssKLRGV----------------AHNL-PG 189
EKM83021     176 RLIPGSIFINYFASDRSHMLipd------qgReAAIYISPPPEHAPLcgaeaRKAGV----------------KNNLmER 233
EDR10947     132 RLVPGELYIQHFASDRSHMLvpanrgrddlgStPPVYKSPPPPYGVLcgplaPS-------------------KNNLmKS 192
XP_004990422 128 RVVKRDDFLAHFSSDRSHMLr------------DGDYIAAPPPYPPI-----QRNGV----------------ATNL-MK 173
EPB87294     124 RLIPAKAYLDHFESDRSHML-----------NeNGEYTATPPQYPAI-----IKKG-----------------KSNL-DN 169
XP_001009551 139 RVVESATLIEKFASDRSHMVtk-------vvKgVKMYQSQPPKYDCIv----NKSNE----------------TNNLfPF 191
A0C2P2       117 RVVDGQKYIDYFASDRHHMIk------------NGKYLQPPPQYPCIkgskqEK-------------------NNNL-QD 164 Paramecium tetr...
6KGJ_A       178 FISMDPK-----VGWG-AVYTLSEFTHRF 200
EEC43125     257 FSAPQKSqrdslSEFG-VILSKNEILEYS 284
EED93993     219 FIDMSEAknq--ttyG-EVFTLDQLCARF 244
XP_007843738 190 FISMWST-----DGYG-RVFSFEDADTFF 212
EKM83021     234 FVTMDASg------eG-EVVGLEEAVGRF 255
EDR10947     193 FVTTTPSe----DTYG-EVFDRVGMELIF 216
XP_004990422 174 YIEMSHEd----RDKG-VVCATLDAVLEY 197
EPB87294     170 YISMKQDdtq--dvhG-TVMKSDDFYQSL 195
XP_001009551 192 YLEISQQn----LSYGnNFMNEIEFNQFI 216
A0C2P2       165 YLDTTNNd----PLLG-KWMTEEQFQQFF 188 Paramecium tetraurelia
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