Conserved Protein Domain Family
Calc_CGRP_IAPP

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pfam00214: Calc_CGRP_IAPP 
Calcitonin / CGRP / IAPP family
Statistics
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PSSM-Id: 459715
Aligned: 50 rows
Threshold Bit Score: 60.917
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003254979   1 MKLISVALMYLGsLAFLGA-----DTARLDVASEFrkkwnkwalsrgkreLRMSSSYPtgLADVKAGpaQ---TLirpqD 72 
XP_006642558   1 MKLILQIAFFC--WCLLASgvfsvESAKLNLTSQLkkrvsiwalnrmkrdLKSSSVSK------LSEadSfhmQFvsqdD 72 
NP_001313638   1 MQLILQSIFCC---CLLAAvapgvDSAKHD----Lkrsvwl---qrskrdL-SLPALR------ALEn-R---QFvrpdD 59 
XP_007234281   1 MNLIILSLFCC---CLLITitpsvNSAKFNLSQVLkrsvwl---qrtkrdLSSLSALR------ETQsgP---QFvrpeD 65 
CAF99639      33 MKLIVQSFLYC---CLLATv---aRCGEFDVKPQLrkrpsiwfrnrlrrdLDRVSVER------TEEl-Q---HFvspdE 96 
Q75XW8         1 MKLIFQSFLYC---CLLATv---aHCVEFDAKPQLkkrlnillrnrlrrdLARVSVGK------TEEl-Q---HFvrpeD 64  torafugu
XP_011487228   1 MARIFHSVLFC---CLLATl---aHCMELDVNPELkkrlsiwlesrmirdLDSTTAEK------TAEt-Q---HFvtpeD 64 
XP_005989751   1 MRLVQVSFLYL---SSMPImflilEAAALGVASEYkrrsgawklgrvrrnVKSLIKPK------TQGd-AveyEFvraeD 70 
EHB08034       1 MKLVSVALVLLGaVAFLDA-----DAAPLDRAPELlkkwnkwavsrekreLPVTDSNPigLADAEAGstQ---TDlgpqD 72 
XP_003465742   1 MKLVSVALMFLGsLAFLGT-----DAAQLDGASETlkkwskwtvsrgkreLPVPSSNFpgLENAKAGsvQ---RAlgpqN 72 
XP_003254979  73 MKGasrspeDsspDAARirVKRyrqsmnnfqglrsfGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSkISPQGYGRRR 150
XP_006642558  73 VKDtlsphsSp--D-TNirVKRymnsvs---qskrtGCSLSTCSVNDLAHRLYQIGDKQRVHSAPLHkISPTGYGRRR 144
NP_001313638  60 VKDnlrphsSt--D-ISirAKRsknsin---qsrrsGCSLGTCTVHVLAHRLHDLNNKLKIGNAPVDkINPYGYGRRR 131
XP_007234281  66 VKDsllphsSa--SHTGmrTKRskssvi--nqskrsGCALGTCTMHDLAHRLQQLNNKLKV--APIEkIGALGYGRRR 137
CAF99639      97 VRVtrlphsSt--D-FNvrTKRsknsgn---qtrrqGCSLGTCIVHDLAHRLHQLGNKYKFGNAPEDkMSPQGYGRRR 168
Q75XW8        65 IRDtllphsSt--D-INirTKRsknlvn---qsrknGCSLGTCTVHDLAFRLHQLGFQYKIDIAPVDkISPQGYGRRR 136 torafugu
XP_011487228  65 IRDtllphsSs--G-SIvrTKRskisns---qsrrqGCSLGTCTVHDLAHRLHELN--LRIGSAPADkISPKGYGRRR 134
XP_005989751  71 VKDslyprpSf--D-AHirVKRyrq---------miGCRLGTCTLQNLAHQIYQLTDKGKDNVAPTNqISSTGYGRRK 136
EHB08034      73 LKSgsgrpqPsgrEASLtrVKRhrqs------lrsfGCRFGTCTVQKLAHQIYKFTDKDKDGFAPQSkISPHGYGRRR 144
XP_003465742  73 LESlsrirqAsgpKIVLnrVKRhrqg------frsfGCRFGTCTVQKLAHQIYQLTDKDKDGVAPRSkISPQGYGRRR 144
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