Conserved Protein Domain Family
Dev_Cell_Death
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pfam10539: Dev_Cell_Death 
Development and cell death domain
The DCD domain is found in plant proteins involved in development and cell death. The DCD domain is an approximately 130 amino acid long stretch that contains several mostly invariable motifs. These include a FGLP and a LFL motif at the N-terminus and a PAQV and a PLxE motif towards the C-terminus of the domain. The DCD domain is present in proteins with different architectures. Some of these proteins contain additional recognisable motifs, like the KELCH repeats or the ParB domain.
Links
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Statistics
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PSSM-Id: 463141
Aligned: 49 rows
Threshold Bit Score: 158.453
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5VQH0        22 GGVVFCCNNNTFDECFTKQLFGLPQRNILYVKNVKPGLPLFLFNYSNRQLHGIFKATSTGQLNIDRFAWmseqsnd-akt 100 Japanese rice
XP_003059938  33 GGVIFICSRETYDDTTRAGLFGLTQGSWSFVKRITPGMPLFLYNLTERRFHGVFEATSDGAMNADPTAWktsgagagdaa 112
EFJ09015      31 GGFIFFCNDETMPEDFERCLFGLPRSFIDSVKGIRKGLPLFLYNYSNRCLHGVFEASSDGGLNIEPDAWinkda----rs 106
XP_004981020 182 GGYIFVCNNDTMQEDLKRQLFGLPARYRDSVRAITPGLPLFLYNYTTHQLHGVFEAASFGGSNIDPTAWedkk------- 254
EEF35711      21 GGVIFGCKKNTMSECLSEQIFGLPAPHFSYVKNIDPGLPLFLFNYENKKLYGIFEAAGAGQMNINPYGWttd-------- 92 
KRH00341      35 GGIIFGCKNATMKECLSKQLFGLPAHHFCYVKNIDPGLPLFLFNYTDRKLHGIFEAASSGRMFIDPYGWttd-------- 106
XP_022564240  19 GGVVFGCTKDTIKECLSKHLFGLPYNHISYVQKIDTALPLFLFNYSDRKLHGIFEAAGPGLLNINPYAWtsn-------- 90 
NP_001331423  19 GGVVFGCTKNTIKECMSKQLFGLPSNHYPYVQKIDIGLPLFLFNYSDRTLHGIFEAAGCGQLNFDPYGWtsd-------- 90 
XP_006360826  28 GGVIFGCTNKTIRECLSKQLFGLPVLHFSYVQNVDSGLPLFLFNYSDKKLHGIYEAAGPGQMYIDQYAWtsd-------- 99 
XP_006339276 182 GGVIFGCTVSTMNECIRNQLFGLPAPHISYVKNIDPGLPLFLFNYSNRELHGIYEAASSGRMNINPYGWtld-------- 253

Q5VQH0       101 nakTTPFPAQVRFS--------TRTECPPLPESKYKSVIINNYRkDKpSHFRFELDHRQTRDLISLF 159 Japanese rice
XP_003059938 113 gidGSPYPAQVRYKhtrvtcsaSAASCKPFLRFAAGEA--------NgKKFRLDLTPGEATRLARVF 171
EFJ09015     107 gvdVSRYPAQVRVR--------IRENRAPLEEDAFRPVL---FH-YEaKKFRLELSMSEVLAtly-- 159
XP_004981020 255 ckgeSRFPAQVRIR--------IRKLCKPLEEDSFRPVL---HH-YDgPKFRLELSIAETLSLLDLC 309
EEF35711      93 gsrRTQYPAQVQIR--------VRLQCHPLSEEKFKPIIADNYY--RyHHFWFELDHAQTSKLMSLF 149
KRH00341     107 gseRTQYPAQVQIC--------VRLKCHPLPEDKFKEVIADNYY--ThNRFYFELDHAQTSKLISLl 163
XP_022564240  91 gsdRTSFPAQVQIS--------ARLQCEPLSEEQFKSAIEDNYY--TpHHFWFELDHLQTNKLICLl 147
NP_001331423  91 gseRTSYPAQVPIS--------VRLQCEPLSEEKFKPAIADNYY--SsHHFWFELDHFQTRKLTCLl 147
XP_006360826 100 gsvRTPYPAQVQIR--------VRLLCQPLLENQFKPVIKDNYY--GqNHFLFELDHVQAGKLISIF 156
XP_006339276 254 gsgRTEYPAQVQVR--------LRLHCRPLAESLFKPIIQENYY-HDqRHFTFELDHVQAGNLISkf 311
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