Conserved Protein Domain Family
SVWC
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pfam15430: SVWC 
Single domain von Willebrand factor type C
SVWC is a family of single-domain von Willebrand factor type C proteins from lower eukaryotes. The canonical pattern of most von Willebrand factor type C (VWC) domains is of ten cysteines, however this family, largely but not exclusively of arthropod proteins, contains only eight. SVWC family proteins respond to environmental challenges, such as bacterial infection and nutritional status. They also are involved in anti-viral immunity, and all of these functions seem linked to SVWC expression being induced by Dicer2.
Links
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Statistics
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PSSM-Id: 464713
Aligned: 80 rows
Threshold Bit Score: 39.6872
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_002426862         51 CT---------TVEPGKSWDLTPFCGRSTCVVaegeqAGRLLelVEDCGPLPKAn--PKCKLSektNKTAPFPDCCpi-f 118
5_pfamImport          1 CTdee----gaFRKLGEIWTERKSCTQRRCLTsv-gdKAIVQ--IQRCPKIEAS---ENCTIKe--ANGNDFPDCCks-l 67 
XP_002058172         35 pqycsdtlsgrQLYVGEVFTRSGQCVRVQCLG-----TLQLW--EDSCKVPGALk--GACNVLpptEANEDYPRCCpm-y 104
WGS:AAPU:GI16062-PA  31 qqycrdtltgrQLYVGEVFTRPGQCVRVQCLG-----TLRVW--EDTCKVPVGLk--GDCHELpptETDSVYPKCCpl-y 100
XP_002106655         35 qqfcmdtltgrQLYIGEVFTREDQCVRIQC-------LESQQlwEDSCQVPKLTq--GNCKPVpstEPHAEYPRCCpl-y 104
WGS:AAPU:GI22106-PB  41 CVihspngklvVINSDETIRYPGKCAEVYCGR-----NGWAL--IYTCPKEYPP---TDCVFGdyfDINAPYPDCCarhv 110
FlyBase:CG34215-PA   37 CVle-----glVLEKGQSARHPQRCERIICGE-----NSAAE--IQSCGAYGLP---PGKKFGkytNPNADYPDCCnrei 101
XP_002006065         41 CQtp-----mgHLNAGEEINDDKTCGIFVCQDd----DGNGL--YQFCQSPVNF---ANCEFDl-vNTKGQFPDCC---- 101
EEC10811              5 CSfe-----ghLMSHGEVVKKGEPCESYECDAe----NELMA--IKRCHYGVYQgapPNCTLQ---KNPGEFPTCCpw-p 69 
XP_002434567         37 CAyd-----ghLLSHNSALDRQSPCEKVICDTe----QRVVY--IGLCSPVANP---ENCEIR---TRDERYPYCCpq-p 98 

XP_002426862        119 EC 120
5_pfamImport         68 VC 69 
XP_002058172        105 EC 106
WGS:AAPU:GI16062-PA 101 EC 102
XP_002106655        105 EC 106
WGS:AAPU:GI22106-PB 111 DC 112
FlyBase:CG34215-PA  102 in 103
XP_002006065        102 -W 102
EEC10811             70 QC 71 
XP_002434567         99 YC 100
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