Conserved Protein Domain Family
ERG4_ERG24

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pfam01222: ERG4_ERG24 
Ergosterol biosynthesis ERG4/ERG24 family
Statistics
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PSSM-Id: 250456
Aligned: 5 rows
Threshold Bit Score: 615.603
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P36209   7 KSAPREFGG-AKGALAIMTGFP----CLMYYLWACSKFNDSQFIKPESFTIAGFQNFFRTLGHYIYVGa-----yPTRYA 76  Schizosaccharomyces p...
P38670  17 RQQHYEFGG-PIGAFGITFGLPilvhVFNLFCNDISGCPAPSLLHPKSLDLAQLKREIGWPDNGVFGLf-----sWSATL 90  Neurospora crassa OR74A
P32462   8 RTTEFEFGG-LIGALGISIGLP----VFTIILNQMIRPDYFIKGFFQNFDIVELWNGIKP--LRYYLG--------NREL 72  Saccharomyces cerevis...
P23913 175 EEIYAEKKIfEAIKTPEKPSSK----TKELEFGGRFGTFMLMFFLPATVLYLVLMCKQDDPSLMNFPPlpaleslWETKV 250 chicken
P25340  34 NEIEYEFGG-TTGVIGMLIGFP----LLMYYMWICAEFYHGKVALPKAG--ESWMHFIKHLYQLVLENg-----iPEKYD 101 Saccharomyces cerevis...
P36209  77 FLVFwsFCIVQAVMYLTLPGVRTQGLPLKhrNNERLPYLCNAIWS---FYTTIVILAVLHVTHVFPITTFIDMFGPLMSV 153 Schizosaccharomyces p...
P38670  91 WTLG--YYALSLVQYRFLPGHHVEGTELS--TGGRLKYKLNAFNSamcTLAILAAGTIAQGAEFPVWTFISDNFAQIISA 166 Neurospora crassa OR74A
P32462  73 WTVYclWYGILAVLDVILPGRVMKGVQLR--DGSKLSYKINGIAMsttLVLVLAIRWKLTDGQLPELQYLYENHVSLCII 150 Saccharomyces cerevis...
P23913 251 FGVFllWFFFQALFYLLPIGKVVEGLPLS--NPRKLQYRINGFYA---FLLTAAAIGTLLYFQ-FELHYLYDHFVQFAVS 324 chicken
P25340 102 WTIFltFWVFQIIFYYTLPGIWTKGQPLShlKGKQLPYFCNAMWT---LYVTTTLVLVLHFTNLFRLYVIIDRFGRIMTC 178 Saccharomyces cerevis...
P36209 154 AIITAFVCTFVLYTGTLLFGDRLFD---------KPHRLSGNPIYDAFMGACLNPRLGk----LLDFKMFFEVRIPWFIL 220 Schizosaccharomyces p...
P38670 167 NILFAFALAIFVYVRSFDVKPGNKDmr-----qlAAGGVTGSLIYDFYIGRELNPRITlpligQVDIKEFMEMRPGLLGW 241 Neurospora crassa OR74A
P32462 151 SILFSFFLATYCYVASFIPLIFKKNgngkrekilALGGNSGNIIYDWFIGRELNPRLG-----PLDIKMFSELRPGMLLW 225 Saccharomyces cerevis...
P23913 325 AAAFSMALSIYLYIRSLKAPEed----------lAPGGNSGYLVYDFFTGHELNPRIG-----SFDLKYFCELRPGLIGW 389 chicken
P25340 179 AIISGFAFSIILYLWTLFISH-------------DYHRMTGNHLYDFFMGAPLNPRWG-----ILDLKMFFEVRLPWFTL 240 Saccharomyces cerevis...
P36209 221 FFISVGAAVRQYETYGTVSPQVLFVCLG--HYLYANACSKGEQLIVPTWDMAYEKFGFMLIFWNMAGVPFTYSHCTLYLF 298 Schizosaccharomyces p...
P38670 242 IILNCAFIAKQYRLYGYVTDSILFITAI--QAFYVFDGIYMEPAVLTTMDITTDGFGFMLSFGDVVWVPFMYSTQTRYLS 319 Neurospora crassa OR74A
P32462 226 LLINLSCLHHHYLKTGKINDALVLVNFL--QGFYIFDGVLNEEGVLTMMDITTDGFGFMLAFGDLSLVPFTYSLQARYLS 303 Saccharomyces cerevis...
P23913 390 VVINLAMLLAEMKIHNQSMPSLSMILVNsfQLLYVVDALWNEEAVLTTMDITHDGFGFMLAFGDLVWVPFVYSLQAFYLV 469 chicken
P25340 241 YFITLGACLKQWETYGYVTPQLGVVMLA--HWLYANACAKGEELIVPTWDMAYEKFGFMLIFWNIAGVPYTYCHCTLYLY 318 Saccharomyces cerevis...
P36209 299 SHdPSVYNWSTqyTTGIYVLLLCCYYIFDTCNGQKNHFRnqiygtevhrkTFPQLPWLIIknPTFIRCANGGTLLTSGWY 378 Schizosaccharomyces p...
P38670 320 VH-PQQLGAFG--LIAVGAVLAAGYSIFRLSNSQKNNFR-----------TNPEDPSVKH--LTYLQTKTGSRLITSGWW 383 Neurospora crassa OR74A
P32462 304 VS-PVELGWVk--VVGILAIMFLGFHIFHSANKQKSEFR---------------QGKLEN--LKSIQTKRGTKLLCDGWW 363 Saccharomyces cerevis...
P23913 470 GH-PIAISWPv--AAAITILNCIGYYIFRSANSQKNNFR-----------RNPADPKLSY--LKVIPTATGKGLLVTGWW 533 chicken
P25340 319 YHdPSEYHWSTlyNVSLYVVLLCAYYFFDTANAQKNAFRkqmsgdktgrkTFPFLPYQILknPKYMVTSNGSYLLIDGWY 398 Saccharomyces cerevis...
P36209 379 RYARKIHYTADFFQSLSWALITGFQ--------------------------------SPLPYFYPCFFFVVLVHRVSRDI 426 Schizosaccharomyces p...
P38670 384 GIARHINYLGDWLQSWPYSLPTGIAgyqilsagsnapgaitmldgrevvqgeargwgIVFTYFYILYFAILLIHRDLRDD 463 Neurospora crassa OR74A
P32462 364 AKSQHINYFGDWLISLSWCLATWFQ--------------------------------TPLTYYYSLYFATLLLHRQQRDE 411 Saccharomyces cerevis...
P23913 534 GFVRHPNYLGDIIMALAWSLPCGFN--------------------------------HILPYFYVIYFICLLVHREARDE 581 chicken
P25340 399 TLARKIHYTADWTQSLVWALSCGFN--------------------------------SVFPWFFPVFFLVVLIHRAFRDQ 446 Saccharomyces cerevis...
P36209 427 KKCKAKYGADFDEYCRICPY-LFIPYIF 453 Schizosaccharomyces pombe 972h-
P38670 464 EKCSKKYGDDWEKYKKLVKW-RIVPGIY 490 Neurospora crassa OR74A
P32462 412 HKCRLKYGENWEEYERKVPY-KIIPYVY 438 Saccharomyces cerevisiae S288C
P23913 582 HHCKKKYGLAWERYCQRVPYtHISLHLL 609 chicken
P25340 447 AKCKRKYGKDWDEYCKHCPY-VFIPYVF 473 Saccharomyces cerevisiae S288C
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