2BIW


Conserved Protein Domain Family
COG3670

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COG3670: COG3670 
Carotenoid cleavage dioxygenase or a related enzyme [Secondary metabolites biosynthesis, transport and catabolism]
Statistics
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PSSM-Id: 442887
Aligned: 191 rows
Threshold Bit Score: 185.431
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BIW_A        12 Q------------------------------------------RSY-----------SPQDWlrG-YQSQPQEWD----Y 33 
WP_004512454   2 Ninrrdflklagag-----------------glalalpgcagnLPLpkevf-pdfgdSGRPWl-GlATSLREEHD----Y 58 
WP_013193561   2 Dd----------------------------------------sEPLdntsf-psldeQDTPSplGlATSVDGEYS----Y 36 
WP_014804372   2 Lvsgkdtsgasaa------------------eneqrfvgksidVPKanshakrmptaPANLFleGnFAPLRHEFNlaktR 63 
WP_046904347   2 Ga------------------------------------------------------fPQTIHfiGtNTPRRVEMAv---R 24 
WP_082348013   2 IsgtpsghgfsakpslpvmflcravlpiggfpvhfdsnkterdMPEif--------hAAASFgqQeKKPLRFEADv---F 70 
WP_050433694   2 Lldrlltvaptgl-------------------ravlgrpskegEPAqp-------asSSNAYlrGnFAPLREETHt---E 52 
WP_058900148   7 Tstg--------------------------------------------------lqfPDDVVfnGyAAPVRIEGEv---H 33 
WP_069051429   2 Evr-----------------------------------------------------fPDLPLytGwGKPLRTESTv---D 25 
WP_066969283   2 Ad------------------------------------------------------fSRTHPlsGfFAPTRFEADv---I 24 
2BIW_A        34 WvEdVEGSIPPDLQGTLYRNGPGLLEIGDR-PLKHPFDGDGMVTAFKFpGDGRVHFQSKFVRTQGYVEEQKAGKMIYRGv 112
WP_004512454  59 EaR-IEGTIPSALRGTLYRNGPALFDRGGL-RKRTLLDGDGMVQSFTV-GDGGVRYRNRYVRTEKFVAEEAAGRFLYPT- 134
WP_013193561  37 EaE-IEGTIPNDLKGTLYLNGPGLFDRGNL-RKRYIFDGDGMIQSFHF-HEGGVYYQNKFVRTDKFVDEQEKGKLLYAS- 112
WP_014804372  64 QfE-IRGKVPRDLNGSFYRNGPNPQFEPG--PFYHWFLGDGMLHAFHL-QRGEVSYLNRYVATPTLELERRAGRNLFLG- 138
WP_046904347  25 NlE-VEGEIPAEVDGAFFRAVPDNAHAPMF-EDDIALNADGMISCFRF-TGGAVDFEIKYVETERYKAEKEARRALFGR- 100
WP_082348013  71 DcE-IEGEIPDSLQGAYFRAGPDRQYPSL--ENDIVLNGDGQVSAFWF-EDGRVRFRSRYVMTERLRREREAHRRLYGA- 145
WP_050433694  53 AlEvVAGEVPRGLAGALFRIGPAPRFEPIDaLRYHWFDGDGMVDAFHF-DGGRVSHRRRWVRTDKFRHEEEAGRALFGG- 130
WP_058900148  34 DlE-VIGRIPPELEGMYIRNSADHAYPPLH-GKDIFLNGDGMVHSVRI-QNGHADLTMRYVRTRKFQLERSARRAMFGA- 109
WP_069051429  26 GlElIEGTVPAELDGTWYRAGPDRQYAPML-GDDIFIDGEGMAHMIRI-RDGSVSYRSRWVRNARFNAQAAAGRSLFGK- 102
WP_066969283  25 DcV-VTGAIPSELDGAFYRMHGDWIYAPKF-TDEPSLSADGYISMLRF-RDGSVDYRGRYVKTDRYLRQVAARKQLYGY- 100
2BIW_A       113 FGSQP----AGGWLKTIFDl-------------------------RLKNIANTNITYWGDRLLALWEGGQPHRLEPSNLA 163
WP_004512454 135 WSTQK----PGGFWGNFWQa------------------------gSVPNQAGITVFWWRGKLYAFDEGNIPYELDPESLA 186
WP_013193561 113 WTTLA----PGGPISNIFGr-------------------------KLESQAGVTVIERNGKLYAFDDGSYIYELDPDTLE 163
WP_014804372 139 QRTNMla-nLQLVGGNLISlisglird-----------knadaytRLIAKANTSVLAFREELFALVESSPPIRLQPTTLA 206
WP_046904347 101 YRNPFtd-dPSve-------------------------------gVDRTVANTTPVWHAGRLFMTKEDGRGYEINPHTLE 148
WP_082348013 146 YRNKYsd-dPSvsn-----------------------------apARDNTGNTYAFAHHGDLYALREDSRPHRIDPATLE 195
WP_050433694 131 MRDLAtstpPGGWIALGFSpmellelharstfgvplrddqihrvmRSQDRSNTNVLQMAGRLLSLEESSAAYELDPRTLE 210
WP_058900148 110 YRNPFtd-aPEva-------------------------------gEDANTANTSVLWHHGKLYALKESGRPYELDPNDLT 157
WP_069051429 103 YRNRFtd-dPSve-------------------------------gISGGTANTNVIFHNGRLLVLKEDDLPFEVDPDTLD 150
WP_066969283 101 YRNPYsd-dPEvrdi---------------------------arpNLRTAANTTPVVLAGKLYATKEEGLPYEIDPNTLE 152
2BIW_A       164 TIGLDDL---GGiLAeGQPLSAHPRIDPAStfdggqPCYVTFSIKS--SLSSTLTLLELDPQGKLLRQKTETFPGFAFIH 238
WP_004512454 187 TAGPSNL---GLtpG-TAFYSAHPKLDPHT------GEWLHFGVKY--GPRPLLHLSAFAADGSLKRHRTFPLPRYVYMH 254
WP_013193561 164 TKGKTQLglnKSkIp--VNFMAHSKIDGQT------EEWILVs-----GLKDKLNITTVDKNDNLVKFQKVKIPKNSYIH 230
WP_014804372 207 SEGFEKF---DAgFM-A-PFTAHPKTDPQT------GYLYAFGYRV--AGGPRLEYYVINPHGKLVSRTAVETDYAAMIH 273
WP_046904347 149 TIGKWDY---YGaLK-SETFTAHPRIDAST------GEMFFFGYEAggLCSLDVAYGIADKDGNLKSEVWFDQPYCSSIH 218
WP_082348013 196 TLPIGDF----GrLQ-STAVTAHPKIDPVT------GEWWSYGVFArgEPTTDASLHVFDRDGKLVREEWFQTPFPGLSH 264
WP_050433694 211 TRGRFTF---GGvLD-VAPMVAHPKVDPKT------GVIYTFGYG---SVPPYVVYYVFGPDGALRLRRPIDTTYPSMMH 277
WP_058900148 158 TRGETDF---GGqLK-SRTFTAHPKIDPLT------GECIAFAYNCegVASDEIEVYRIGKDGEFLKTERFKAPYCSMVH 227
WP_069051429 151 PIGIYAF---DGkVR-ATSLSAHPKWFPDD------GRLLTYSYQAkgDGSNDVVFYDMDDHGNIHDEIWFEMPWASICH 220
WP_066969283 153 TRGPSDF---LGsWP-SLTFTAHPKFDFFT------GETVAYGYEStgLATNDVHVAAFDRTGRVTWSLDFQVPYASMLH 222
2BIW_A       239 DFAITPHYAIFLQNNVTLNGLPYLFGLRGAGECVQFHPDKPAQIILVPRD-GGE---IKRIPVq-AGF-VFHHANAFEEN 312
WP_004512454 255 DWIVSGRYLILSLHPVEIEFWGFLLGFRSLFASLRWRPEWGNLLMIVERE-GEGk--PRLVETe-ACY-MWHSFNAYEEG 329
WP_013193561 231 DFFVSDNHIILNFQPAEPYVFKFMSGLSSFLESLYWRPKQGNILLVLNRN-EEGevePYQFSVe-SSW-MWHTLNAYEEG 307
WP_014804372 274 DFAITRNYAVVPVFPAVTSLASIRRGR-----IAEWQPEKGASVIVMNKDgDTAs--LRRFELp-VGY-VYHYANAYEDG 344
WP_046904347 219 DFVITEKYAIFPIFPTLADLDRLKDGG----AHWAHDQDKPSYVGIMPRYgDASq--IRWIEGpkGVS-CFHEVNAYDDG 291
WP_082348013 265 DWGVTREHIVFPIMPLTADDARLRRGG----DYYEYDPDLSSAWGIMPRNgSTDd--IRWFRIp-NLV-MGHVMNAFTEG 336
WP_050433694 278 DFSVTETRAVFYHLPATLWMDNMKSG-----EPVRWEPSRGARIGVTARDdADAp--VRWIDIp-PCY-VFHPMNAYDDG 348
WP_058900148 228 DFLVSRNFIAFVICPMVCEWDRVKKGE----SYWHWDSQKQTYIAVIPRDqGGSa--IRWYTAp-KIAmQTHTFNAWDDG 300
WP_069051429 221 DFAVTPHYAIFPFMPLVTTLDNIKRGT----TFYEWHPDKQVVVALVKRGgKAEd--IRWFRGp-AGS-LSHMMNAFEDG 292
WP_066969283 223 DMALTKDFVVIPGGGTVTSLERLEAGR----PHWAWDSKRPSYYAIIPRGgRTEd--VRIFEGp-ERS-IVHTANAWNDG 294
2BIW_A       313 GKIILDSiCYNSLPQ---VDTDGd--FrSt----nFD---NLDPGQLWRFTIDPA---AATVEKQLM-VSRCCEFPVVHP 376
WP_004512454 330 GETVADFiGYRNPDHfvgDDPVIsavMeGr----rGH---YDFPGEIMRYRIDPV---RCTVRRETL-NPGSCEWPRIDE 398
WP_013193561 308 NKIVADFvGYRYPEQifgDDPTFyaiMeGr----eKK---SDYPGEIRRYIIDLD---KETVQQQVL-DGANYEYPVVNQ 376
WP_014804372 345 KAIVVDAiRYERVPL------M------GsdteirAElfeQANNGYLTRFRIDLA---SGKTETQVLhSEHYAEFPVIDP 409
WP_046904347 292 DFVHLDLcLTDTNAF-----SFMre-agGih---rDQ---QDIKGALTRWTIDMSk-dDPQIESREL--GPPGDLPRLAD 356
WP_082348013 337 NVVHVDTpFSPGNCF-----SFFqd-knGrs---pTP---AEGVTQISRISFDLSkpaEEAVTITPV-EGALGDMPRIDD 403
WP_050433694 349 ETLVLDIaRYPRLPL---FDLG------Gea---pNPriqDNPEARLTRLRVDVQ---RGTVTEEAL-DEDAMEFPVVDP 412
WP_058900148 301 NRLVLDHfVNESGWL-----SQFpdi------hnpDA---DELPPFGERWIVDLSt-aGGDVQIERF-INHIGEMPVVDG 364
WP_069051429 293 DKVHLDAcYYDGNCF-----PFFpt-peGkh--------vEGCPPILSRLTFDLSr-nDDGFDRRPL-INTPGEMPRADD 356
WP_066969283 295 EKLVLDApIADGNTW-----PWFed-vdGga--------fAMNIFTIRRITFDLRs-nSNKPTEDVLfDRDVTSFTRIDD 359
2BIW_A       377 QQVGRPYRYVYMGAAHHSTG----------NAPLQAILKVDLESGTETL--RSFAPHGFAGEPIFVPRPg-----gVAED 439
WP_004512454 399 RLRCRRHRIGYAVKClp------------gEFFWSIVMRVDFLSGTTAE--YSFGRGKYCTEAVFVPKPgtsadasQSAG 464
WP_013193561 377 YHSCRKHKYGYFVRAHKPEDv-----------FWSSVVRMDMDTGLPEF--YDFGKGYYCTEPVFVPKPgynyssdINDE 443
WP_014804372 410 RLVGEKYEHSFAASASGNNSs--------aAGIFDGQVSYELSRGKVKAdiHDFPRGHFGGEPIFVPTg------kPGER 475
WP_046904347 357 ADQGRNYNRAWYLSMNPQPKgppml-ggpvGINFNALLRIEPGNGRITM--MEPTPGSALSEPVHVVAn-------DPDH 426
WP_082348013 404 RFAMDKYRIGYFALRd---------------fPNMGIGQLDWESGDLVF--HAL-EGAAAQEPVFVPRSp-----dAPEG 460
WP_050433694 413 RHAMRPYRYGWAVSRRGACad--------eRGMFNAITRYDLQERRVQR--RLFGRASFPSEPIVVPRSa-----tSAEG 477
WP_058900148 365 RFSMRRTRHFWFGTNHPAKWpmlp--agpkGPPFTCLGHFDEHTGKISL--FYAGPDSSPEEPCFVPRSp-----dAEEG 435
WP_069051429 357 RYQGQACGKGYLIVGRQPD-------------GSSGIGCVDLATGELTR--WAPGALASVHEPQFVPRYk-----gSAEG 416
WP_066969283 360 RFLTRPNRYIWVQYADPDRPfhaalpedprVRPVNCYGRFDLVSGTDLA--WFAGPDHVLQEPLFVPRTp-----hADEG 432
2BIW_A       440 DGWLLCLIY---------KADLHRSELVILDAQDITAPAIATLKLKHHIPYPLHGSWA 488
WP_004512454 465 EGWLLTEVY---------DSHTRKSFLAILDAGRVADGPLAIAHLTHHVPFSYHGWWH 513
WP_013193561 444 PGWILTEVY---------DSYLKKSFLAILQADNLESGPVAKVHLKHHVPLSFHGFWK 492
WP_014804372 476 KGYLLNLIY---------STEDNRSYLAVFDVAKPDKKPLCEIWLPHRVPYGFHGTWR 524
WP_046904347 427 GGWLLLVVDtpngppgqgNPSDYSSELWILEADFIEKGPIAKVKTGLALRSQVHGTWV 484
WP_082348013 461 DGYVLAAVD---------RFAERRTDLLVLDGNDVSRPPIATVKLPFALPMAFHGCWM 509
WP_050433694 478 EGWLLTVVY---------HADEDRSELVVLDALDVEGAPVAVLRCPHRIPYGFHGSFV 526
WP_058900148 436 DGWLMTMVG---------RRAENRTDLVILDARNLSQGPVAILKFPCRVHEGFHGIWV 484
WP_069051429 417 DGWLLVIVN---------RLDAGHSELAILDAQDITRGPVARLHLPVRVRSTFHGTWV 465
WP_066969283 433 DGYLIGTMH---------NLVELRTEIVILDAMKML--EIGRVILPFRNPYQVHGTWA 479
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