4KXR


Conserved Protein Domain Family
PE
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pfam00934: PE 
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PE family
This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis. The C-terminus of this domain contains the type VII secretion signal that has a YXXXD/E motif.
Links
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Statistics
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PSSM-Id: 425952
Aligned: 249 rows
Threshold Bit Score: 30.9316
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4KXR_A               6 VITNPEALTVAATEVRRIRDRAIQSDAQVAPMTTAVRPPAADLVSEKAATFLVEYARKYRQTIAAAAVVLEEFAHALTTG 85  Mycobacte...
zhongguo:AS9A_0088   5 LYVNPEALWEAAQRLEAMAHRITADLARCASALSPV-PAGLDEVSLAAARWSSSASSSLNHRTHAAVAELRAASGALAAI 83 
WP_005516359         5 VYVDPDVLLAAAGEIEALVTRLQTSLAVHSPALN-VAPSGAEEVSVLAAGYFNRLAGSFGAATSRGIEELAAAAAMLRAQ 83  Rhodococcus
WP_025346466         5 LGVQPEVVLAASAELDLLAERLAAASALSGPATHVI-PAGAEEVSAMAATHLNEGALSHDRAVAQAILELHHAAAILRTQ 83  Nocardia ...
WP_014360759         4 LSADTAKISEVAGQLGKLADRLNGVLNTADASLTP-QPAGSDEVSVRAATTMGQVHQTFRKAGDGGVAELREISDAVATV 82  Gordonia ...
WP_005062903        25 LQVDPDVMKDAAVEYDAMAQRLQEALDKQLETAKFG-SAGRDEVSTAVSHASAKTNENFEKVAKDGIEQLKRIAEAFRRN 103 Mycobacte...
jgi:Tpau_3373        6 LSMAPQEVRDVARGIERIVEDLRGAQERFAAHAEPA-ATGRDEVSTAVARTTSEIGVAQRALGETAVTDLRVLGEALTRH 84 
Q5Z1M7              11 VQFDPTVAREVATRLDDLADRLEQGLRDNEPALT-VEPAGLDAVSTRAAQTMNQVAANYAENAAAGVLELRKLAAVLRGQ 89  Nocardia ...
WP_025347263         1 MEFDPVVAARTATDLDALADRLEAGLKADTPALK-VDAPGLDEVSRRAAATLTDVGVSFDSSSVMGVQELRKLAATLRAQ 79  Nocardia ...
jgi:Srot_2497        3 VNVEPEAISAAAATLEGLSMKLQAMVAAASPALQMIPPAGYEDVSVFASAQHMFNSDNFLMMAEQSILELQRLIIALNEH 82 

4KXR_A              86 ADKYATAEADN 96  Mycobacterium tuberculosis H37Rv
zhongguo:AS9A_0088  84 AADYSANDETF 94 
WP_005516359        84 AAAYREEDRTL 94  Rhodococcus
WP_025346466        84 LASFIADDAIE 94  Nocardia nova
WP_014360759        83 SSSLADTDTDQ 93  Gordonia polyisoprenivorans
WP_005062903       104 SQAFVDLEHHN 114 Mycobacteroides abscessus
jgi:Tpau_3373       85 ADTVQRQDSDL 95 
Q5Z1M7              90 VDEFGRAEDDN 100 Nocardia farcinica
WP_025347263        80 ARGLTQMDADN 90  Nocardia nova
jgi:Srot_2497       83 AMEYTAQDAGN 93
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