7OZM


Conserved Protein Domain Family
Hydrolase_4

?
pfam12146: Hydrolase_4 
Serine aminopeptidase, S33
This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
Statistics
?
PSSM-Id: 463473
Aligned: 76 rows
Threshold Bit Score: 181.644
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
7OZM_A         55 TAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHGRSG------GARV-LVRDISEYTADFDTL-V---GIA 123
EHA47486       25 GAPKAKLVLIHGFSDHVNLYNDFGNAVANGGIAVYGFDQRGWGRSVktpadrGKTG----PTSMVLADIVAF-I---EPL 96 
Q6CBY1         39 AQPKGKLVFNHGFTEHIGVFDELFKRMVDNGYYVLALDQRGAGEQCq-----GKKY-GITNETFVYEDLNGViK---EYL 109 Yarrowia lipol...
A0BYJ7         70 QIVDAQVIIVHGFGEHSGNYQQLTDSFLFNNFKVYLYDQRGFGYSG------GIRG--QATVEQMHMDLDTV-LqlvDRS 140 Paramecium tet...
jgi:Asuc_1643  61 SKPKAVLVISHGLASHSGVFADFAKQMNENGIAVYRFDARGHGKSD------GRDSiHINSYFEMVEDLRLV-V---EKA 130
Q5HPN9         25 KSTIGIVHLFHGMAEHMDRYQELVEALNTQGYDVVRHNHRGHGKEId----eNERG-HFNSMNQIVDDAYEI-I---ETL 95  Staphylococcus...
Q88EB5         25 TPVKAVVLLAHGMAEHAGRYQRLGQALSEAGFALFAADQRGHGRTAelg-nlGLFA-RHHGWNAVVNDLGCV-A---QHI 98  Pseudomonas pu...
jgi:Pmen_1494  35 APPRATVMLAHGMAEHSLRYARLAEALVAAGFALYALDQRGHGRSAehg-tlGHYA-DEDGWNKVVGDLSTL-N---HHI 108
Q9HYU2         24 ATAVGAVMLSHGMAEHAGRYERLAAALNAAGYHFYAIDQRGHGRTAead-elGHFA-DQGGWGKVVGDLASL-N---HHI 97  Pseudomonas ae...
Q3ADP4         27 QKLRAIVYIAHGMAETAARYERFALALTKEGYLVFAHDHRGHGKTAksieeiGYLG--PDGFNRMVQDMKEL-I---DFV 100 Carboxydotherm...
7OZM_A        124 T-REYPGC----KRIVLGHSMGGGIVFAYG--VERPD----NYD-LMVLSAPAVA-AQd-------lVSPVVAV-----A 178
EHA47486       97 L-DDGSNL----PVFVMGHSMGGGQVLTLAgdQKYEAnvvsRVQ-GWILEAPFIAwPAg-------qAPSWLKIn----V 159
Q6CBY1        110 VkNNSIEQskkeKLFIWGHSMGGGIALNYGvkGLYRD----HFT-GFIGCAPLVQlHPasvpn-----------filrgA 173 Yarrowia lipol...
A0BYJ7        141 V-----------PLFIFCHALGASMVISFC--LMNPSf---QFQ-GLICSNAQLRvPAk--------yGKFKML-----T 190 Paramecium tet...
jgi:Asuc_1643 131 K-AENPNT----PVFVMGHSMGGHITALYG--TKYPQ----GAD-GVILAAGVLRyNQmnfghlprpEPKDSFVngfeaA 198
Q5HPN9         96 Y-LEELNV----PYIIIGHSMGSIIARSFV--EKYPD-----IAqGLILTGTGMFpKWkg-----vpIRLAMKL-----V 153 Staphylococcus...
Q88EB5         99 G-QQFPCT----PLFLFGHSMGSYIAQAYL--LHHSG----SLH-GAILSGSNYQpAVly-----rfARLIARL-----E 156 Pseudomonas pu...
jgi:Pmen_1494 109 R-QQHPHT----PIFLFGHSMGSYIGMAYL--MGHSC----SLQ-GALLSGSNYQpVAly-----kaARLIAGF-----E 166
Q9HYU2         98 R-QQHPEL----PIFLLGHSMGSYISMAYL--LHHSC----SLQ-GAILSGSNYQpQAly-----riARLIARF-----E 155 Pseudomonas ae...
Q3ADP4        101 K-NENREL----PIILFGHSMGSFLAQRYI--SLYGE----SIN-GVILSGTSCDpGPiv-----nlGIFLAKK-----E 158 Carboxydotherm...
7OZM_A        179 AKLLGVVVPGLPVq--------------ELDFTAISRDPEVVQAYNTDPLVhHGRVPAGIGRALLQVGETMPRRAPALT- 243
EHA47486      160 GRFAGKFMPYRQLe-------------hVIPPKDLTRNQEVVKILENDKLC-HNLGTLEGLASLLDRTVDLASGKTKL-- 223
Q6CBY1        174 MEVLARAWPTLHFp-------------aDLKMDYIVSNPDSQKKLEADEWI-RPMCTVKQMYDMFQRGNALVDPDYVANy 239 Yarrowia lipol...
A0BYJ7        191 LKLMTKLCPDLQVn-------------tYHNLSYASKNNHHIKKLATDHLM-HPYMSIQFAYNVLLFQQFILPNATKFR- 255 Paramecium tet...
jgi:Asuc_1643 199 HKTLNLPMPEMGAg----------------------------lSLPNDPLM-LEKFSVSFPNSFKEGIKYLKNNDDKFI- 248
Q5HPN9        154 TFIFGKRRRLKWVnqllnktfnkkitqpRTDSDWISTRQDEVDKFVEDEFC-GFKVSNQLIYQTLKTMMKTVERQQLKRm 232 Staphylococcus...
Q88EB5        157 SWRQGPLGKSALIewlsfgsfnnafkpnRTAFDWLSRDPGEVDQYVNDPLC-GFRCTNQLWLDLLQGLAQISQPGNLAQi 235 Pseudomonas pu...
jgi:Pmen_1494 167 RWRLGPKGRSKVIdflsfgsfnkafkpnRTAFDWLSRDAAEVDKYVTDPLC-GFVCTTQLWCDLLDGLQHITPPGNLAQi 245
Q9HYU2        156 RWRQGPLGKSALIdflsfgsfnkafkpnRTAFDWLSRDPQEVDRYVADPLC-GFRCSNQLWVDLLGGLADITPPTHLRQi 234 Pseudomonas ae...
Q3ADP4        159 VEKYGPKHRSVRLtklsfgnynkkfkpnRTEFDWLSRDAEEVDKYINDPYC-GGVFTASFYYDFLRGLKETFRRENLAKi 237 Carboxydotherm...
7OZM_A        244 ---AP----LLVLHGTDDRLIPIEGS----RRLVECVGSA-DVQLKEYPGLYHEVF-NEPE 291
EHA47486      224 ---LPsvkaMWLGHGTADKACDHDAS----KKFFDEQTRLqDKEFRSYDGWYHQMH-TEPD 276
Q6CBY1        240 qrdAA----VLIYHSEHDKINWYEAS----KKFIDAVPVK-DKQLFDAKGCEHSIH-LEQA 290 Yarrowia lipolytica
A0BYJ7        256 ---IP----ILLLHGKEDKVASHLDS----LDFYRIIQSK-EKTLKIFDQGFHELH-NDSE 303 Paramecium tetraurelia
jgi:Asuc_1643 249 ---AP----VLLVSGDADLYVVPKDA----IQFYEEVNST-DKSLRLYNGLGHMLMiGEGG 297
Q5HPN9        233 dkeLP----ILFISGKDDPFGEYGKGikhlARLYKRVGIK-HITVQLYKHKRHEIL-FEED 287 Staphylococcus epidermidis RP62A
Q88EB5        236 dpnLP----MLVIGGECDPVSA-GKRlthlADALRATGNR-HVQLRVYPEARHEVL-NETN 289 Pseudomonas putida KT2440
jgi:Pmen_1494 246 dadLP----LLVIGGSRDPVSD-GKRladlAGALREAGVR-DVQLKIYPEARHELL-NESN 299
Q9HYU2        235 dadLP----LLIIGGERDPVSQ-GKRlgdlADALRGAGLR-QVTLKTYPEARHELF-NESN 288 Pseudomonas aeruginosa
Q3ADP4        238 pkeLP----IFIFSGDMDPVGNMGRGvlklIKTYEKLGLK-NVAYKLYPGGRHEML-NEIN 292 Carboxydothermus hydrogenoformans...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap