1ZYL,6EF6


Conserved Protein Domain Family
SrkA

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COG2334: SrkA 
Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist [Signal transduction mechanisms]
Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist is part of the Pathway/BioSystem: Threonine biosynthesis
Statistics
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PSSM-Id: 441905
Aligned: 626 rows
Threshold Bit Score: 68.413
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1ZYL_A         14 DTI-MDAL-FEHgIRVDS--GL--------TPLNS--Y-ENR-VYQFQDEDRr-RFVVKFY-RpeRWTADQILEEHQFAL 75  
WP_015884285   45 HAL-KAHLeASYgIRITS--MLpidddprtRPRGSwpGhYPS-TLLVEREQGt-PWIARVFsSp-aDQVSRVKEDAEILG 118 
WP_068759514    4 NQL-KEILa-CYfLSDc---QI--------HQGAS--GmNNL-TRFIEHE-Gk-KYVLRVY-Qn-hSDENLVQVEQEILK 63  
WP_087458648    4 QAFeQ-----LWpDAPgp-wTW--------EPAGV--GfINL-TYRVQSPLGs--FFSRIY-Qn-cNAQELVQHEIRVME 62  
WP_038591352   19 DAI-EDVLrDHYgL---Sg-QI--------FPIEG--R-QNP-YFLIDN--GhlRYLLKIS-PanD-PIEEIEAEHALMR 77  
WP_129886833    4 QQLw-----QAWpVAGPW--QI--------FPMVG--G-TNTlIWRALAADGq-QYALRIIpn--lARISHLRYEASLLE 62  
WP_130111114   17 NDA-RAIArACYgI---Ev-SV--------RELGS--N-QDR-NFVLEQPDGt-RSVLRVD-NpaF-GDEARDAQHAALE 76  
WP_071894501   15 ELA-QTIAqQYFgV---TavSV--------TELGS--N-QDR-NFLLHElDGk-QSVLKID-NaaF-PLVEIEVQNDALG 75  
NP_746272      30 AQA-HAVLqAHYgL---Ag-NL--------SVLGS--Q-QDL-NFRVVTPQGg--YVLKAC-HgsY-AQLELEAQHAALA 88  
SQF93792       20 EQA-EQLLaQHYqL---Sg-AL--------KELGS--Q-QDR-NFLVDTGTHr--YVLKIC-HgdY-SAVELEAQHAALG 78  
1ZYL_A         76 QLVN--DEVP--VAA-P--VA-FNGQ-TLLn-----hQG--FYFAVFPSVGG-R--QFEA----DNIDQMEAVGRYLGRM 132 
WP_015884285  119 FLAD--HGFP--AER-Pa----VEGGvSVV-------DG--SGVLLTEFIPGgR--PTDAdarvTSPDVFHELASLLGRL 178 
WP_068759514   64 RI----KGVP--VPV-L--VPtMRGD-YLVrl-------ydKIAVLFEYQEG-V--NLKLer----lDQYKNYGEMIGKL 119 
WP_087458648   63 LLDA--QRLSfaIPV-P--VVtATGQ-RTAhvv--taEGqeRLLALFPLIPG-Q--HPq----aDDPEQAEASGRGLGEL 127 
WP_038591352   78 HILRspDGPR--VPE-P--VMtKDGG-DMLvlp-lggED--RRVRLLTFLEG-A--SPPTge-kLSDRSVAAFGSISAEL 144 
WP_129886833   63 ALAA--TQPP--V-QlPllLRaRDGD-SIVec---elEGkaALATLSPLLSG-RlpDLlp--drHDPSIAVDAAQVLAWL 130 
WP_130111114   77 AYRT--AGVP--APA-V--LPgLDGA-LTQrs----eQG--FAVRRSEFADG-E--PMVDig-yLAPVVLEEFGALAAAS 138 
WP_071894501   76 ACVA--AGVP--VAN-V--IRgTDGV-AIRtivdidgTE--HFARRFQFVPG-T--SLLDaq-yLSAVMMQQVGALSGKV 141 
NP_746272      89 FLRD--QGLP--VPA-V--RSaHNGM-GLLeld-idaQP--LRLRLLDYIEG-Q--PLTRlk-hMEPRLMAELGGLCAKL 153 
SQF93792       79 HLADh-STVN--VPG-V--VRaTNGE-QLLtle-lggNR--VHVRLLEFIDG-Q--ALSHlr-hLPADVVVGLGELCAQV 144 
1ZYL_A        133 HQ------TGR----------KqlFIH-------RPT-I-G-LN-EYLIE--PRKLF-------EDatlipsglKA---A 173 
WP_015884285  179 HTlpegrgAAArdggaeehdgG--Fhl-----grP---RqDlVAa-------MRFLVsve-----------dkvAP---P 227 
WP_068759514  120 SR------ALG----------K--LEVdke-gysPy---yE-LDeAYPNHq-ICEFCqh---pyEEfe----slH----E 164 
WP_087458648  128 VR------VMG----------Q--IDEpalcagvP----------LYGALekVHPLVpdplrlaETl--------PvsvE 171 
WP_038591352  145 AK------SLQ----------D--FEH-------PVLeR-Ep---EGD----LRKAGpq---tvSLlst---vaDQ---E 182 
WP_129886833  131 DT------ALA----------Q--LSPqsl-agsP---Q---LP-TFGTLknRQGPIedplvclQQl--------PaapE 176 
WP_130111114  139 AN------ALV----------G--LRH-------PGLdR-D--H-MWI----MDVAHeq---tlLLaps---iaDE---T 176 
WP_071894501  142 SA------ALK----------N--FAH-------PGLhR-S-T--QWD----LRRAVev---seSLlds---idDG---A 179 
NP_746272     154 DK------ALA----------H--FDH-------PGLaR-T-L--QWD----PQHAGal---idHLlpv---lqDG---G 191 
SQF93792      145 DR------SLA----------A--FEH-------PGLeR-I-L--QWD----PRHAQal---ikHLlpi---isNE---D 182 
1ZYL_A        174 FLKATDELIAAVTAHWREdftVLR---LHGDCHAGNILWRD-G-------PMFVDLDDARNGPAVQDLWMLLNg---Dk- 238 
WP_015884285  228 GRETFERLRDQVESTDDAe--GLPeafTHSNFHVWAAVgDP-Gr------LSIVGWAGSGRGPRLPALAWLLr---tAs- 294 
WP_068759514  165 ELKVVERVYEDLMNLSERf-kTLPqqlIHGDINSSNLLMDE-Agm----iSRILDFEFVTKDLRAMEIAICLSeils--e 236 
WP_087458648  172 KQRRMAALLQEMTAKVPElydALPrqlIHRDYTKGNTLLAA-Rn-----vTGVLDFEFCARDLRALDLAIGLGegpanqm 245 
WP_038591352  183 IRDVIAKAMVTALRRIQPfgpSLRvaaAHQNLNAGTVIgEDtDgtw--mpTGVTDFSGISNGWLVAGFANTCAyllaDr- 259 
WP_129886833  177 KIQQLSSFLEEVIELVPGlyrRLPqqiLHRDYDPANILAEG-Qr-----vTAVLDFELAGPDLRALDLCGALSwwpv--q 248 
WP_130111114  177 LRERVLDAADEARAALDEvtdVLPqqaIHGDLTDDNVMGRR-GedarlhpSIVLDLGDLAYGWRVSELAVTAAsmlhHd- 254 
WP_071894501  180 RRERVRAALKAAQRILGQl-gELPvqaVHGDITDDNIMWGG-Pqqs--dqLTLLDFGDVSTGWRVAELATTLSsllqHt- 254 
NP_746272     192 QRARIEHATRQANEHLMPlvdQLPsqaVHLDITDDNTVWAR-DaqrqwqlQGVIDFGDLLRTWRIADLSVTCAallhHa- 269 
SQF93792      183 ERACIAEAAEQAQRRLISlipALPlqtVHLDITEYNVVWSR-EsatqwrlQGLIDFGDLVTTWRIADLSGTCAallhHa- 260 
1ZYL_A        239 ---A-EQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRR--WA--DPAfpknfp---wltgeDYWLRqt 307 
WP_015884285  295 ---Eg-RPEFVDAVMRGYRQHVSLTDAEIDRLPAVLNMRPLWLACLEYREavRAgqTPVlddd------ggygFYRPErs 364 
WP_068759514  237 gqdE-VwPR-LEAFIEGLKQSLQLTKEETEVLPSLILLRRLDVVMHFIVRy-RRniSSEivg---------kgEFLSKqi 304 
WP_087458648  246 wgtG-AEWVWLENFARGYASEHCLTAAEVDALPMLMRLRRAYFLLHFAGRc-LEglDSTgwlrgivdwvldleNWMEQha 323 
WP_038591352  260 ---D-GDPFALLPAIRAYHEIYPFTLAELEALWPLVVARTGILAAEAESQ---QalSPDd-------------tQAKEet 319 
WP_129886833  249 llgSgQEWALMETFATAYLARFPLSEEELLALPDLCRMRDATSLVQRVGRy-LTgqESEgviqrrvehslwreAWIVAnr 327 
WP_130111114  255 ---A-RRPLRVLDTVAAFHRDAPLSEAEARAVWPLVVLRGAILVASGWRQ---LeiDGGn-------------dYARDri 314 
WP_071894501  255 ---A-ERPLDVLVAARAFHQQQALTSSEVSALWPLVVLRACVLVTSGAKQ---LelEADn-------------dYAAEri 314 
NP_746272     270 ---E-GDPLRILPAVQAYQALNPLTEAELRALWPLVLNRAAVLVLSSEQQ---LtvDPGn-------------qYTRDni 329 
SQF93792      261 ---E-GDPLYILPAIRAYHAINPLQLEELQALWPLIIARSAVLVLSSEQQ---AviEPDn-------------tYIQAni 320 
1ZYL_A        308 atfi-----------eqakvL----QE 319 
WP_015884285  365 ehla----------ahaiaaLg---D- 377 
WP_068759514  305 vklveqsswieengnrlielLsnce-- 329 
WP_087458648  324 eelirkvk---rgwdafydeVdk-tQA 346 
WP_038591352  320 ek--------------rravL----NG 328 
WP_129886833  328 qtl-------------qehaLtwrhKA 341 
WP_130111114  315 ag--------------eqriF----DA 323 
WP_071894501  315 eg--------------ewriF----DE 323 
NP_746272     330 ah--------------eweiF----DT 338 
SQF93792      321 as--------------ewgiF----DV 329 
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