Conserved Protein Domain Family
PRK06349

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PRK06349: PRK06349 
homoserine dehydrogenase; Provisional
Statistics
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PSSM-Id: 235783
Aligned: 514 rows
Threshold Bit Score: 441.819
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
220909625  15 RVTFKVGLLGLGTVGTGAVQILLHPLGRHPLLQ--ELSLHRVAVRSLDKPRQVNLPTELLTTDLQAIVTDPEIDIVVEVM 92 
21282944    1 MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLnkDIVIKHILVRDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVM 80 
27467927    1 MKELNIALLGLGTVGSGVVKIIEENRQQIKDTInkDIVIKHILVRDKSKKRPLNISQYHLTEDINDILNDNSIDIVVEVM 80 
224476457   1 MKKLNIALLGLGTVGSGVVKIIEENHQQIKDTIqkDIQIKHILVRDKKKKRPLNISQYHLTEDVDEILNDDEVDIVVEVM 80 
289550884   1 MKELNIALLGLGTVGSGVVKIIEENRQQIKDTInkDIIIKHILVRNKAKKRPINFQQYHLTEDVHEILNDDSIDIVIEVM 80 
49486172    1 MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLnkDIVIKHILVRDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVM 80 
57866811    1 MKELNIALLGLGTVGSGVVKIIEENRQQIKDTInkDIVIKHILVRDKSKKRPLNISQYHLTEDINDILNDNSIDIVVEVM 80 
70726580    1 MKELNIALLGLGTVGSGVVKIIEENRQQIIDTLnkDIVIKHILVRDKSKKRPINISRYHLTEDVNEILNDDSIDIVIEVM 80 
87161755    1 MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLnkDIVIKHILVRDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVM 80 
88195050    1 MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLnkDIVIKHILVRDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVM 80 
220909625  93 GGIEPARSLILTAIAQGKHIVTANKAVIARHGDEIFTAARQAGIYVMLEAAVAGGIPVIQPLKQCLGANRVHTVTGILNG 172
21282944   81 GGIEPTVDWLRTALKNKKHVITANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG 160
27467927   81 GGIEPTVDWLRTALKNKKHVITANKDLLAIHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGIFNG 160
224476457  81 GGIEPTVEWLKKSLEQGKHVITANKDLLAVHLRTMEDLAQENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG 160
289550884  81 GGIEPTVDYISRTLKSGKHVITANKDLLAVHLRLLEDLAEANGVALKFEASVAGGIPIVNAINNGLNANNISKFMGIFNG 160
49486172   81 GGIEPTVDWLRTALKNKKHVITANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG 160
57866811   81 GGIEPTVDWLRTALKNKKHVITANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGIFNG 160
70726580   81 GGIEPTVDWLRDALKSGKHVITANKDLLAVHLKLLEDLAEEKGLALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG 160
87161755   81 GGIEPTVDWLRTALKNKKHVITANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG 160
88195050   81 GGIEPTVDWLRTALKNKKHVITANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG 160
220909625 173 TTNYILTRMQQERGDFQAILADAQRLGYAEADPSADVDGDDAAAKIAILASLAFGGRIKLEQVYCEGIRQVSATDIAYAE 252
21282944  161 TSNFILSKMTKEQTTFEEALDEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKRRGISGVTLTDINVAD 240
27467927  161 TSNFILSKMTHEQTTFKDALEEAQRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKSVGISDITLADINAAN 240
224476457 161 TSNFILTKMTQEGASFEEALAEAQRLGFAEADPTDDVEGVDAARKVVIVTYLSFNRVINLDDVKRTGISEVTVDDINAAK 240
289550884 161 TSNFILTKMFQEHTSFEEALNEAQRLGFAEADPTDDVEGIDAARKVVITSYLSFNQVIKLNDVYIKGISETTLDDILVAD 240
49486172  161 TSNFILSKMTKEQTTFEEALDEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKRRGISGVTLTDINVAD 240
57866811  161 TSNFILSKMTHEQTTFKDALEEAQRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKLVGISDITLADINAAS 240
70726580  161 TSNFILSKMTREQTTFEDALDEAQRLGFAEADPTDDVEGIDAARKVVITSYLSFNQVIKLNDVKVRGISQTTLSDINVAD 240
87161755  161 TSNFILSKMTKEQTTFEEALDEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKRRGISGVTLTDINVAD 240
88195050  161 TSNFILSKMTKEQTTFEEALDEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKRRGISGVTLTDINVAD 240
220909625 253 KLGFVIKLLAIAH-RpsdadsftasatgagldkqhTDDR-LEVRVHPTLLPQSHPLASVNGVYNAILIEGEPLgQVMFFG 330
21282944  241 QLGYKIKLIGKGI-Y--------------------ENGK-VNASVEPTLIDKKHQLAAVEDEYNAIYVIGDAVgDTMFYG 298
27467927  241 SLNYKIKLIGKGT-Y--------------------ENGY-VNASVEPTLIHKNHQLAAVENEYNAIYVIGDAVgDTMFYG 298
224476457 241 ELGYKIKLIGKGT-Y--------------------ENGN-IEASVSPTLIDENHQLASVENEFNAIYVIGDSVgETMFYG 298
289550884 241 KLGYKIKLIGKGI-Y--------------------EHGK-VHASVEPTLIHKSHQLASVDNEYNAIYVIGDAVgDTMFYG 298
49486172  241 QLGYKIKLIGKGI-Y--------------------ENGK-VNASVEPTLIDKKHQLAAVEDEYNAIYVIGDAVgDTMFYG 298
57866811  241 ALNYKIKLIGKGT----------------------YENGyVNASVEPTLIHKNHQLAAVENEYNAIYVIGDAVgDTMFYG 298
70726580  241 KLGYKIKLIGKGT-Y--------------------QNSK-VNASVEPTLIHKSHQLATVEDEYNAIYVVGDAVgDTMFYG 298
87161755  241 QLGYKIKLIGKGIyE---------------------NGK-VNASVEPTLIDKKHQLAAVEDEYNAIYVIGDAVgDTMFYG 298
88195050  241 QLGYKIKLIGKGIyE---------------------NGK-VNASVEPTLIDKKHQLAAVEDEYNAIYVIGDAVgDTMFYG 298
220909625 331 PGAGAGPTASAIVSDLINITALLKaglanrqetlaqSTHPLLT---CSHQHYSTIAPMAELVTRFYVRIKAADHPGVLGK 407
21282944  299 KGAGSLATGSAVVSDLLNVALFFE-------------------------------SDLHTLPPHFEIKTDK--------- 338
27467927  299 KGAGSLATGSAVVSDLLNVALFFEsnl------htlPPHFELKteeTKEMMDGAEPVVIQEKSNYYIVISNNNKSLEKVE 372
224476457 299 KGAGSLATGSAVVSDLLNVALQFEsdl------htlPPHFELKtedAKEMIDADEPTKLKQKNSYYVVLKTNGAPLKRVE 372
289550884 299 KGAGSLATGSAVVSDLLNVSLFFEsnlht---lpphFELKTDQ---TKELMDHEHLVTLQEKYSYFVVVNSSETLDKIKE 372
49486172  299 KGAGSLATGSAVVSDLLNVALFFE-------------------------------SDLHTLPPHFEIKTDK--------- 338
57866811  299 KGAGSLATGSAVVSDLLNVALFFEsnl------htlPPHFELKteeTKEMMDGAEPVVIQEKSNYYIVISNNNKSLEKVE 372
70726580  299 KGAGSLATGSAVVSDLLNVALFFE---------------------------------SNTHTLPPHFELKTDATREIMDT 345
87161755  299 KGAGSLATGSAVVSDLLNVALFFE-------------------------------SDLHTLPPHFELK---TDKTREMMD 344
88195050  299 KGAGSLATGSAVVSDLLNVALFFE-------------------------------SDLHTLPPHFELK---TDKTREMMD 344
220909625 408 --LGTCFG-NYGISLESLVQIdvhddraeIVVVTHQVGEGAFHQALDEIRSLEV-VDSIPSLLRVL 469
21282944  339 --TREMMDsDAEINIKEKSNF--------FVVVNH------VKGSIENFENELKaILPFHRSLRVA 388
27467927  373 ydIKKKLPfHKSLQLVERDQD------------TYAIIVTGIETSPEKVLNQSG--FNIKKVYPVE 424
224476457 373 eeIKSQLPlHKSLKVSEHSAD--------TAAVVVEGTDVPVSDILSQG------KYPVEKVYPVE 424
289550884 373 --IIKSNL-PFHKSFDIIKRNdtt--yagVITGVDVSPEQSLKQA----------GIDIIKVYPVE 423
49486172  339 --TREMMDsDAEINIKEKSNF--------FVVVNH------VKGSIENFENELKaILPFHRSLRVA 388
57866811  373 ydIKKKLPfHKSLQLVERDQD------------TYAIIVTGIETSPEKVLNQSG--FNIKKVYPVE 424
70726580  346 ---------EDVVAIQEKLNY--------YIVLNSDLSKEKFKSLLKE-------TLPFHKSLQVE 387
87161755  345 -------S-DAEINIKEKSNF--------FVVVNH------VKGSIENFENELKaILPFHRSLRVA 388
88195050  345 -------S-DAEINIKEKSNF--------FVVVNH------VKGSIENFENELKaILPFHRSLRVA 388
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