Conserved Protein Domain Family
P33MONOX

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pfam15302: P33MONOX 
P33 mono-oxygenase
This family of proteins contains a flavine-containing mono-oxygenase motif. It may have a role in the regulation of neuronal survival, differentiation and axonal outgrowth.
Statistics
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PSSM-Id: 464628
Aligned: 13 rows
Threshold Bit Score: 372.986
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_019219565  13 PGMGGMKLPVGMTRRAISYDDNLE--APMSTPPHDISINNLWKRPIIPERKFTHLAEEDESGASQ---------SAAQDT 81 
XP_005993433  17 GLLGKMSLPIGIHRRAFSYDDALEdtSPMTPPPADMGSRVLWKQPVIPERKYQQLSKVEDGEKSMpp-----pmTPSSSN 91 
XP_006631943  18 GLLGQMSIPIGMTRRAFSYDDALE--APMTPPPADMGTNILWKKPVIPERKFQHLSEQGEEPGAVl--------THSSSI 87 
XP_004073363  18 GFCTPLSPAIGL-RHSIRYDEHMD--IPMHSPPPDINVNTQWKDPIIPQHRFRGREEEGQKDKKAl--------MFEGFA 86 
5_pfamImport   1 GLFGTCASPIGLNRRNVSYDELMD--ATVHSSPPDVAVNIFWKDPVIPRHKFRKNAEEGQIDGKLl--------AFEAAS 70 
XP_007244619  19 GLLGGMSVPMGMPRRAISYDENLE--RPMSPPPSDINITNLWRRPVIPERKFSRLAEEEESENVIk--------NTPALE 88 
A4QNZ7        20 GLLGGMSIPAGMTRRALSYDDNLE--RPMSPPPSDINISNLWKRPVIPERKFARLAEEDESEGGV---------KQSASF 88  zebrafish
XP_008119543  17 SLLGKMSQPIGMSRRAFSYDDALEdtAPMTPPPSNMSSNILWKEPVIPDRKYEELSKVEEEEISMhas----aiVPSSST 92 
XP_003781965  15 GPLGKMSLPIGIYRRALSYDDALEdpTPMTPPPSDMGS-IPWK-PVIPERKYQHLAKVEEGEASVssp----amTLSSAI 88 
2_pfamImport   1 GPPGKMSLP-RMYQQTFSYDDALDdpTP---PPSVMGS-IPWK-PVIPECKYQHLADGACGGGGRtgrcilpgmSLSSAI 74 
CAF95797      13 SGMGGMKLPVGMTRRALSYDDNLE--APMSTPPHDISINNLWRRPVIPERRFTHLAEvEDEGGAQ---------SQGGSH 81  spotted green p...
XP_023818504  13 SGMGGMKLPVGMTRRALSYDDNLE--APMSTPPHDISINNLWRRPVIPERKFSQLAE-EVESGPV---------RESAVP 80  Japanese medaka
CAG01193      15 GLFGVLSSPMGISRRNTSYDALME--APMHSPPSDISVNTLWKEPVIPRHKFRDAVEEKGSSVNLl--------NFEEAA 84  spotted green p...
XP_019219565  82 GASRP--QAVVKTKASSIIMNSLINKQTQDSVYKFEQTAGLSDAGYTPHKGLTAEETRhHHRVPETIQ--KLQIQSMEak 157
XP_005993433  92 ESVNK--APVVKAKATSIIMNSLMTKQTQESIQRFEQQAGLKAAGYTPHKGLPAEEIK-YHRVAEALQ--KLNMQSGD-- 164
XP_006631943  88 DSAAKptAPVVKAKATSIIMNSLITKQTQESIQRFEQQAGLTDAGYTPHKGLTAEETR-YHRLAEALD--KMKMQSGVsk 164
XP_004073363  87 PPKSP--VPVVKAKATS-FMSSLMTKQTQENLDMFEHKAGLTDDAYSPHKGLSAEETH-FHRRADAVS--KLRMPSGDfk 160
5_pfamImport  71 PVKSP--APVVKAKATS-LVSELMIKQTHESLQKFEHQAGLTDAGYCPHKGLSAEETR-FHRLVDGTS--KLRMPSGDfk 144
XP_007244619  89 PPHPP--APVVKAKASV-LMNSLIIKQTQESIQSFEKKAGLTDTGYTPHKGLAAEETR-YHRMSESLQ--KLHMQSGDlk 162
A4QNZ7        89 ESTKP--IPVVKAKASS-VMNSLIIKQTQESMQKFEKQAGLTDTGYTPHKGLNAEETR-YHRLAESMH--KLQMQSTDak 162 zebrafish
XP_008119543  93 ETVSK--VPVVKAKATHIIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTAEETK-YHRVAESFH--NLKMQSGDma 167
XP_003781965  89 DSTDK--IPVVKAKATHVIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEESK-YLRVAEALH--KLKLQSGEit 163
2_pfamImport  75 DSMDK--VPVGKAKATHVIMNSLITKQIQESIQCSEPQAGLRDAGSTPYKGLTTEETK-YLLVAEALHilRLNLHSGEmt 151
CAF95797      82 DLGPSrsSRAVKTKASSLIVSSLITKQTQESMQTFEQRAGLTNSSYTPHKGLTAEETKhHHRMADSLQ--KLQIQSLEsr 159 spotted green p...
XP_023818504  81 DTASFkvPGAVKTKASSIIMNSLITKHTHESMSKFEQRAGLTDTSYTPHKGLTAEETRhHHRMPEALQ--KLQIQNLDvr 158 Japanese medaka
CAG01193      85 PARVM--GPVVKAKATS-LMSSIMIKQTQENLQEFEHQAGLTDVRYSPHRGLSAEETQ-FHRLGDLkp-pKLRMPSGDfk 159 spotted green p...
XP_019219565 158 -eERQSSSAHS--------TPSNTPHSSP--------K------------PQRRGWFgSSSSELSIASSSN-----SSLD 203
XP_005993433 165 --ERQTSSAQS--------TPSNTPQSSP--------K------------QKRRGWF-GPGSTTSLPGAEL-----SSSD 208
XP_006631943 165 -eEKQASSAQS--------TPTGTPQASP--------K------------QKRRGWF-SQGSTAPITSSEFgs-asSNVD 213
XP_004073363 161 -eDRLTTSAQStargtppvTPSVTPSVTPtvsplsspV------------VHRRNWF-HLSSAPFLALPEPdr-rhPNTD 225
5_pfamImport 145 -eDRCTTSNQS--------TPSVTPSVTPsvtphsspA------------VSRRSWF-QQSPVPFLPNPELhs-pnHSTD 201
XP_007244619 163 -eEKQPSSGQS--------TPSGTPQSSP--------K------------QKRRSWFsSQGSTTSLTGSELsssssSSTD 213
A4QNZ7       163 -eERQPSSNQS--------TPAGTPQSSP--------K------------QKRRGWFnSQGSTASLTGSEMstsssSSVD 213 zebrafish
XP_008119543 168 keDKQTSSAQS--------TPSSTPQSSP--------K------------RTYRGWF-SQGTSNSITGPDL-----ASMD 213
XP_003781965 164 keEKQPVSAQS--------TPSSTPHSSP--------K------------HRPRGWF-TSGSSTALPGPNP-----STMD 209
2_pfamImport 152 kaEKQAASAQS--------APSSTPHSPP--------K------------HRPRGRF-TSGSSIALPGPNL-----STMD 197
CAF95797     160 -eERLASSAHS--------TPSSTPHSSP---------------------KQKRSWFgSAGSDL---SSSS-----SSID 201 spotted green p...
XP_023818504 159 -eEK-SSSAQS--------TPSNTPHSSP--------K------------AQRRGWFsSTGSEVSL-SSSN-----SSVD 202 Japanese medaka
CAG01193     160 -eDRLTTSAQS--------TPIGTPSVTPc-------VtpcvspyaspalSRR-AWF-QLSPAALPTSPEAns-pnPSTD 220 spotted green p...
XP_019219565 204 MAGVDvgg--ggGGVVERWGVFGPRpPVHKSTSDLgsdstaaAGFALQAYRGAQKPTPMEVMKTQA-RLADSASIQ--Kv 278
XP_005993433 209 SGVGD-------ITNTERWSLFKPR-TVQKSTTDP-------GGFTMQPYLGGPKPSPMELMKAQAtRIAEDPANF--K- 270
XP_006631943 214 MGGGE-------GGGVERWSIFGPRpVVQKSTTDP-------GGFALQSYRGAQKPTPMELMKAQAtRMGEDPANL--K- 276
XP_004073363 226 MGGNEg-----gGGGLDKWSFFGTRsVVHKSPTDPgse--tsTGFSLQSYFGLQKSSTMDGTNSQItLKVDE-------- 290
5_pfamImport 202 MGGNEg------RGGAERWSFFGSRsVVQKSPTDPg-------cFSLQSYLGMHKSSTMDGTNTQVnFKVDDPANF--N- 265
XP_007244619 214 LAGGE--------GVMERWSVFGPRpQVHKSTSDMggepgtaGGFALQPYKGAQKPTPMEVMKAQAtRLAEDPTNF--Ka 283
A4QNZ7       214 LASAE--------GPIERWGVFGPRpQVSKSTTDPgthpdtsGGFALQSYKGAQKPTPMEVMKAQAtRLAEDPTNF--Ka 283 zebrafish
XP_008119543 214 SSGGDg-----dKIPSEKWSLFGPR-TLQRSTTST-------GGFTIQAYKGAQKPSPMELMRAQAtRMAEDSATF--K- 277
XP_003781965 210 SGSGDk-----dRNPSDKWSFFGPR-SLQKY--DS-------GSFATQAYQGAQKPSPMELIRAQAtRMAEDPASF--K- 271
2_pfamImport 198 SGSRDk-----nRNPSDKWSLFGPR-----------------TSFTTQAYQGAQKPSPVEMIQAQDtAVTEDPATF--K- 252
CAF95797     202 MGEPGg-----gAGALERWGAFGPRpLVHKSTsdlgs-dpssaGFALQAYRGAQKPTPMEVMKSQAsRLADNPVAQaaAa 275 spotted green p...
XP_023818504 203 MGGLDpaagggaGGAVERWSVFGPRpLVQHSASDLgsdgsaaAGFALQAYRGAQKPTPMEVMKSQAaRLTDDPQKV--S- 279 Japanese medaka
CAG01193     221 MGGNEg------GGGGERWNFFGTRsVVQKSPTDPgsd--ssSGFSLQSYFGMQKSSTMDSSSTAGsFKVDDPASF--M- 289 spotted green p...
XP_019219565 279 sPPTMEIPTVEGRr-HGARTHKLKPRDMNILTPSGF 313
XP_005993433 271 -PPKMDAPIVEGK--QPIRTHNLKPRDMNVLTPTGF 303
XP_006631943 277 -PPKMEIPAMEGRq-QASRPHKLKPRDMNVLTPSGF 310
XP_004073363 291 -PPKPEIPGSD-Kr-VPQRPHKLKPRDMNVLTPSGF 323
5_pfamImport 266 -PPKIEISGIETKq-APTKPHKLKPRDMNVLTPSGF 299
XP_007244619 284 -PPKMEIPTVDGKr-QITRPHKLKHRDMNVLTPSGF 317
A4QNZ7       284 -PPKMEIPTMDGKr-QVTRPHKLKHRDMNVLTPSGF 317 zebrafish
XP_008119543 278 -PPKMDIPAMEEKr-RSPRSHNLKPRDMNVLTPTGF 311
XP_003781965 272 -PPKMDIPGMEGKk-QPPRTHNLKPRDLNVLTPTGF 305
2_pfamImport 253 -SPKMVVSVVM-Kk-QPPGTSNLKPADLNVLTSIGF 285
CAF95797     276 -PPKMEIPTVEARr-HGARPHKLKHRDMNVLTPSGF 309 spotted green pufferfish
XP_023818504 280 -PPKMEIPTVEGRr-QGARPHKLKHRDMNILTPSGF 313 Japanese medaka
CAG01193     290 -PPKIEITDLEAKqaPPPRPHKLKPRDMNVLTPSGF 324 spotted green pufferfish
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