Conserved Protein Domain Family
BLOC1S3

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pfam15753: BLOC1S3 
Biogenesis of lysosome-related organelles complex 1 subunit 3
This family of proteins are components of the biogenesis of lysosome-related organelles complex-1 (BLOC-1).
Statistics
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PSSM-Id: 464847
Aligned: 17 rows
Threshold Bit Score: 125.205
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003725108   6 RVVSGEASESd-SD--------DELTAAaelvagrsqssigeeLRQAGVVVQGEASETDSEEDEEMHLAraeqqqfpsqs 76 
XP_003391868   3 SLVQGEDSES--SE--------DEINTDml------------pSHPKGTIMTGEEEEDEDEDIDSSVQD----------- 49 
EDO46662       4 NVTSGEGDESd-DDtcqslsfmKNTMVT-------------------STMVSGEASETDEEDDADDQQEsadddkmhq-- 61 
EEN42794      44 VVVAGEASESedSD--------GEVAAIleggagr--ggmpdpAQKAGVVVSGEASETDDESDTELGSEvtaadrq---- 109
XP_001809744   5 VIISGEASETd-SE--------DEAPKNkplav---------tapiqGAVITGEDSESENENDASICSAv---------- 56 
XP_011151677   6 VVISGEAPESd-DD--------TSNIATglgfpav------rtsnycGTIISGEAPESDDDLTSLSSIS----------- 59 
XP_392613      6 VVVSGEAPESd-DD--------SASIVTgigfpfv------rtpnycGTIISGEAPESDDDGTSLSSVS----------- 59 
XP_006006731   8 VVVQGEASESd-SE--------EEVYLTsthp--------ipfSGSLGSKVPGEASETDEEEEERPRAAsnapkslslgl 70 
XP_005474735   7 IVVQGEASETd-SD--------DEVYITslt-------------psvGAKVPGEASETDSEGEPEQAPAshdsaqilkrd 64 
XP_014327987   8 IVVQGEASETd-SD--------DEVYITslt---------shqTTAGGAKVPGEASETDSEDDAQQAVRsslmaqesaqi 69 
XP_003725108  77 nipplkvnrasrspsigsqSSIK------SVSSASQvKVSPLD----PPR-YDTLLHRKLRERNISLQVSLQEAVAQAIQ 145
XP_003391868  50 -------------------QGKE------EGGSVIS-GDSPSLlrkpQWV-PPSLLHKRLGDANINLRKNIVDRILKLYR 102
EDO46662      62 ----------epveidigdTAIPikidnlEVEDPLAtKQSKVRrqklVFK-HDTPMHRKLRERNLQLRSSLVEGTTQLYK 130
EEN42794     110 -------------qqsatlTAEA------PSESGGQsHAGRPEaekiPAK-YNTLLHKKLDERNRSLKKNIKEFLSASYH 169
XP_001809744  57 -------------------SALN------ETNSTTKtQNCD--------K-YDSLLHQKLRECNGKLHQDIEGFCQGVIG 102
XP_011151677  60 -------------------GAVD------AMTCPPYtDLKIPKskksTIK-YNSLLHKKLHECNETLDKDILQMTEGVIT 113
XP_392613     60 -------------------GAVD------AMTCIP--EMKIPKskkcSIK-YNSLLHKKLHECNETLDKDLIQMVDGTIG 111
XP_006006731  71 tp-----lvvirteqpgspTGVE------ER--PAL-KIGH------GGR-YSTLLEQKLLESNARLQQDVSNAVRQVYQ 129
XP_005474735  65 lp-----plivvrdhpdmhSIVE------DRPSPSH-----------RPH-GETLLQQKLQESNSRLYSDVGQTLRQVYG 121
XP_014327987  70 lkre-lpplivvrdnpdvqSIVE------DRPSPSH-----------KPYaGDTLLQQKLLESNSRLYTDVGQRVRQVYG 131
XP_003725108 146 AKHKEFSNTNQMLTKSQMVIQDVCYSMRHFSDDIKRTNEKLDII--STSGYLPEFN 199
XP_003391868 103 LTCQNLTIVNDNLSRAQVVIEKVNANVKKSDHDLAQLKANLDDIfeSANSLAPNLN 158
EDO46662     131 AASNKLQSSGFFLNKAQAAAEEVAYQSKVILEDLDALQVALQSI--VDMSVLPTIH 184
EEN42794     170 HGNRTIHTSTEHLIKSKAALQDVTHNLSVIQRDLVSLQEKVDII--STCNLLPQLT 223
XP_001809744 103 ENGKNLASIDQQLIKSQLTLQNAVTSLKSLGANSLSIKNKLHSL--LSAQFIPNIK 156
XP_011151677 114 TGVQELSAVNRQLLRSELVLQEAVCQLRNASGRVKDASNALHQL--IDDDFLHSIK 167
XP_392613    112 AATQELTTVNKQLLRSELILQEAVSQLRSACNRTKDASNALLQL--INENFVSSIK 165
XP_006006731 130 TAARQIQASTLQLSNSQNGIINASHSIRLILDDLRAVAETMDII--TSCNLLPDIh 183
XP_005474735 122 SASREVRSATSQLNASQSAIINASHSIRLILDDLKAVSEKIDII--TSYQILPDIN 175
XP_014327987 132 SASKEVHSVTSQLNTSQSAIINASHSIRLILDDLKAVSEKIDII--TSCQILPDIN 185
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