224002114  49 PRMDDTSANLIGGDSFTKRSVNPGWIKVRADVYDAVKERRDKELAEK--VPVDIEVTLPDGKvlSEDKegvkyQAWRTTP 126
145348874   1 ------MADAPTPTNADHAREKSPYYAHRIDLFDKYRARELTRIEEAkaRGEGIKVTLPDGA--QKDG-----TRFATTP 67 
159476198   1 --------MAAASVGPSPVEERMPYYKKRVEVFEKFLEREQAKLEAAkaANVAIKVIMPDGK--ERAA-----VQGVTTP 65 
168064726   1 --MEEKMSSMALSSPADVKGMADTVIKKRVELFEKLQKEQAEAFRAK--GGDPIKITMPDGA--VRDG-----KKWITSP 69 
242033449  54 GKGKAKAPAADSLLVARDDSYLEAVTQKRIRLFEEIQARQAVERLNI--GGEVIKVTLPDGA--IKEG-----KKWITTP 124
255071725   1 MADTEAPVAPTEPAGPSPYEEKAPYYAKRIELFEKYFEREGAKVEEAksKNEPIKVVMPDGA--IKEG-----IKFVTSP 73 
303277979   5 AVAPTDAAPTEEPSGPSPYEQKSPYYAKRIELFEKYFAREGERKTAAeaSNETIKVTMPDGA--VRDA-----VKNVTSP 77 
302816171   1 -------------------MADPAVIQKRIRIFSELQASERARNEKL--GGQPIDVTVHKDGevVYPG-----RRLLTTP 54 
302816173     --------------------------------------------------------------------------------    
302820128   1 -------------------MADPVVIQKRIRIFSELQASERARNEEL--GGQPIDVTVLKDGevVYPG-----RRLLTTP 54 

224002114 127 FDVAATIARGLADNTSVARVTytayvsdynpeedgmggvdtlaesmaeleindadedksklTMLWDMTRPLVGSvSKMEF 206
145348874  68 FDIALGIHKKLAQSALVAKVD----------------------------------------GEFWDMRRPLEGD-CALAL 106
159476198  66 MDIAKEISASLAKKVVVADVD----------------------------------------GHAWDLARPLEGD-CALKL 104
168064726  70 MDVAREISQGLANSALIAEVN----------------------------------------GVLWDMTRPLEGD-CTLQL 108
242033449 125 MDIAKEISSGFASSCLIAQVD----------------------------------------ETLWDMGRPLESD-CKLQM 163
255071725  74 WDIAMGIHKKLAQGSLLAHVD----------------------------------------GQDWDMRRPLEGD-CSLKL 112
303277979  78 WDIAMSIHKKLAQASILAHVD----------------------------------------GKDWDMRRPLEGD-CALKL 116
302816171  55 LDIARLISKKKAADYVIAQVN----------------------------------------GTLWDMGRPLEED-CTLVL 93 
302816173   1 MLLRRLISKKKAADYVIAQ------------------------------------------------------------- 19 
302820128  55 LDIARLISKKKAADYVIAQVN----------------------------------------GTLWDMGRPLEED-CTLVL 93 

224002114 207 LKFEDDvDARTVFWHSSAHVMGEALERLYGSRLTIGPPLA--GGFYYDSYMGD-SssdgALKE-EDYKPVEAEVQKIVKS 282
145348874 107 FTFDDE-EGKECYWHSSAHVLGEALELEYGADLTIGPAIE--EGFYYDCYLGE-R----TLTP-EDTEIIKGRMEKIIKE 177
159476198 105 FSFDDT-EGKDAFWHSSAHLLGQALELEFGVDLTIGPALE--EGFYYDCFMGD-R----TLTE-ADKARLEKRIEGSVKE 175
168064726 109 HKFESD-KGRDTFWHSSAHILGQSIEMTYGCKLCIGPCTTrgEGFYYDAFYHG-L----TLTEkDDFGKIQAQANKAVKD 182
242033449 164 FKFDTN-EGRDTFWHSSAHILGESIERAYGCKLCIGPCTTrgEGFYYDAYYKD-Q----TLNE-EHFGIIESQAKKAVAE 236
255071725 113 FGFDDP-EGKELYWHSSAHVLGEALELEYGADLTIGPSIE--EGFYYDCFLGE-R----TLSA-SETDGIQKRMEAIIKE 183
303277979 117 FSFDDP-EGKELYWHSSAHVLGEALELEYGADLTIGPSIE--EGFYYDCYLGD-K----TLSD-HERTQIQKRMEGIIKE 187
302816171  94 YAFKDE-QGRDTFWHSSAHILGESLEQAYGCKLCIGPCTTrgEGFYYDAFYEDgR----TLNE-ENFPAVQSQVTKAVQE 167
302816173  20 ----DE-QGRDTFWHSSAHILGESLEQAYGCKLCIGPCTTrgEGFYYDAFYEDgR----TLNE-ENFPAVQSQVTKAVQE 89 
302820128  94 YAFKDE-QGRDTFWHSSAHILGESLEQAYGCKLCIGPCTTrgEGFYYDAFYEDgR----TLNE-ENFPAVQSQVTKAVQE 167

224002114 283 KQKFERLVVTKEEALDMFAGNPFKEQIIStKIADGSRTTVYRCGDLVDLCRGPHVPNTGRIKAFAATRHSATNWLGDTDN 362
145348874 178 KQEFQRIVVSRAEALEMFEENKFKIELIS-NLPEDATISCYRCGPMVDLCRGPHLPDTAWLKSVSVNQCSRAHWRADVTK 256
159476198 176 SQKFQRVVVTREEALSMFEENKFKIEIIQ-GLPADATITIYRVGPMVDLCSGPHLPSTSYMKAISVTQMSRAFWRGDVKR 254
168064726 183 KQPFERIEVTREQALEFFAENPFKVEIIN-ELPEDKTITVYRCGPLVDLCRGPHIPSTSHVKAFACLRASASYWRGRADR 261
242033449 237 KQPFERIEVSRAEALEMFAENEFKVEIIN-ELPEDKTITVYRCGPLVDLCRGPHIPNTSFVKAFACLKASSSYWRGKVDR 315
255071725 184 KQPFQRIVVSRAEALEMFQENKFKVELIS-NLPEDATISCYRCGPMVDLCRGPHLPDTAWIKTVSVNQCSRAHWRADVTK 262
303277979 188 KQPFQRIEVSRDEALEMFLENKFKVELIT-NLPEDATISCYRCGPMVDLCRGPHLPDTAWIKAVTVNQCSRSHWRADVTK 266
302816171 168 SQPFERIQVTRQQALEIFSDNQFKVEIIN-DLPEDAVITVYRCGPLVDLCRGPHIPNTSYVKAFSCLKASACYWKGKQER 246
302816173  90 SQPFERIQVTRQQALEIFSDNQFKVEIIN-DLPEDAVITVYRCGPLVDLCRGPHIPNTSYVKAFSC-------------- 154
302820128 168 SQPFERIQVTRQQALEIFSDNQFKVEIIN-DLPEDAVITVYRCGPLVDLCRGPHIPNTSYVKAFSCLKASACYWKGKQER 246

224002114 363 DSLQRMYGISFPDKKMLKVWQENQEKAKERDHRRIAQQQDLVMFHELSAGSAFWLPHGARIYNKLIEFIKEHYWRRGYDE 442
145348874 257 DPLVRVYAVTFPSDKLMKEYTTRIEEAKKRDHRTIGLNQELFFFHHLSPGSCFFQKHGARIYNNLVQFIREKYWEYEYDE 336
159476198 255 EPLQRVYGVTFPDSKLLKDYQHRMEEAKKRDHRVVGVQQELFFFHPLSPGSCFFLPHGARIYNNLVGYIREKYWEYEYEE 334
168064726 262 ESLQRVYGISYPDNKLLKEYLHNVEEAKKRDHRKLGQQQELFFFHELSPGSCFFLPHGARIYNKLQAFIRDEYRKRGYEE 341
242033449 316 ESLQRVYGISFPDSRRLTEYKHFLEEAKKRDHRILGKAQELFFFHELSPGSCFFLPHGARIYNKLMDFMRQQYRARGYQE 395
255071725 263 DPLVRVYAVTFPDKKLMAEYKLRIEEAKKRDHRLIGLNQELFFFHTLSPGSCFFLPQGAKIYNKLMEFIREKYWEYEYDE 342
303277979 267 DPLVRVYAVTFPTDKLMKEYKLRIEEAKKRDHRVLGLHQELFFFDILSPGSCFFLPDGATIYNNLINFIKEKYWEYEYSE 346
302816171 247 ESLQRVYGISYPDNQSLKAYMTKYEEAKKRDHRLLGKNQQLFFFHELSPGSAFFLPKGTIVYNKLLQFIRSEYRKRGFDE 326
302816173 155 ----------------LKAYMTKYEEAKKRDHRLLGKNQQLFFFHELSPGSAFFLPKGTIVYNKLLQFIRSEYRKRGFDE 218
302820128 247 ESLQRVYGISYPDNQSLKAYMTKYEEAKKRDHRLLGKNQQLFFFHELSPGSAFFLPKGTIVYNKLLQFIRSEYRKRGFDE 326

224002114 443 IITPNIYNLDLWHQSGHAMHYKDAMFCFDVEGKEWAMKPMNCPGHCLMFAGKIRSYRDLPIRFADFGVLHRNELSGALSG 522
145348874 337 VITPNIYNFDLWKTSGHAAHYKENMFSFNVEKEEFGLKPMNCPGHCVMFAHRHRTYRELPMRVADFGVLHRNEFSGALHG 416
159476198 335 VITPNIYNFDLWKTSGHADHYRENMFSFDIEKQEFGLKPMNCPARALHAPDRL----------------------GTLSP 392
168064726 342 VVSPNMFNMQLWETSGHAANYKDNMFTFEVEKQEFGLKPMNCPGHCLIFDHRVRSYRELPLRLADFGVLHRNELSGALSG 421
242033449 396 VLSPNMYNMQLWETSGHAANYKENMFVFEIEKQEFGLKPMNCPGHCLMFANRVRSYRELPLRMADFGVLHRNELSGALTG 475
255071725 343 VITPNVYNFDLWKTSGHAAHYKENMFSFDVEKAEFGLKPMNCPGHCVMFGNRKRSFRELPMRLADFGVLHRNEFSGALHG 422
303277979 347 VVTPNIYNFDLWKTSGHAAHYKENMFSFNVEKEEFGLKPMNCPGHCVMFGHRKRSFRELPMRLADFGVLHRNEFSGALHG 426
302816171 327 VVTPNIYNMKLWEQSGHAAHYKENMFVFEIEKQEFGLKPMNCPGHCLLFQHRVRSYRELPLRIADFGVLHRNELSGALTG 406
302816173 219 VVTPNIYNMKLWEQSGHAAHYKENMFVFEIEKQEFGLKPMNCPGHCLLFQHRVRSYRELPLRIADFGVLHRNELSGALTG 298
302820128 327 VVTPNIYNMKLWEQSGHAAHYKENMFVFEIEKQEFGLKPMNCPGHCLLFQHRVRSYRELPLRIADFGVLHRNELSGALTG 406

224002114 523 LTRVRRFQQDD----------AHIYCREDQIEDEVLGALDFMKSVYDTFGMTYKLELSTRPAKALGDKELWDRAEAALAR 592
145348874 417 LTRVRRFQQDD----------AHIFCREDQMEQELSGFLQFLDDVYEVFGLTYEMKLSTRPEGYLGELEVWDKAEAALKS 486
159476198 393 HTTTLLYPHRPppppppvpgyAFTSLVIMSVMAEVQGFLKLLGEVYEVFGLDCTMALSTRPEGYLGDIELWNKAEQALTD 472
168064726 422 LTRVRRFQQDD----------AHIFCMESQLLTEVKGALDFLEFAYGVFGFTFELELSTRPEKYLGEIETWNRAEKALEA 491
242033449 476 LTRVRRFQQDD----------AHIFCREDQIKDEVKAVLDFINYVYEIFGFKYELELSTRPEKYLGEIETWNKAEQQLTE 545
255071725 423 LTRVRRFQQDD----------AHIFCRQDQMEKELAAFVKMLDEIYEVFGLTYEMKLSTRPEGYLGELETWNKAEAALEA 492
303277979 427 LTRVRRFQQDD----------AHIFCRPDQMEHELVNFMKFLDEVYEVFGLTYEMKLSTRPEGYLGELEVWNQAEDALRN 496
302816171 407 LTRVRRFSQDD----------AHIFCMESQVYDEVKGCLDFLDYVYTIFGFTYDLKLSTRPENFLGESSLWDRAEGALAD 476
302816173 299 LTRVRRFSQDD----------AHIFCMESQVYDEVKGCLDFLDYVYTIFGFTYDLKLSTRPENFLGESSLWDRAEGALAD 368
302820128 407 LTRVRRFSQDD----------AHIFCMESQVYDEVKGCLDFLDYVYTIFGFTYDLKLSTRPENFLGESALWDRAEGALAD 476

224002114 593 AMDTFAGKggWRENPGDGAFYGPKIDIKVMDAMERVHQCATVQLDFQLPIRFGLEYNTgskEKGSEFARPVMVHRAMLGS 672
145348874 487 ALDRSGRE--WKLNEGDGAFYGPKIDITVFDALKRRFQCATVQLDFQLPIRFDLSYVD---ENNS-SVRPIIIHRAILGS 560
159476198 473 ALNSTGKA--WVLNPGDGAFYGPKIDITVYDALRRKFQCATVQLDFQLPIRFGLEYAS---EAGT-LERPVIVHRAVLGS 546
168064726 492 ALNAFGKP--WQINEADGAFYGPKIDITVFDALKRKFQCATIQLDFQLPIRFNLSYST---EDEAKREKPVIIHRAILGS 566
242033449 546 ALNEFGKP--WKINEGDGAFYGPKIDIGVFDALKRKFQCATLQLDFQLPIRFKLAYSA---EDEAKIERPVMIHRAILGS 620
255071725 493 ALNGTGKE--WKLNPGDGAFYGPKIDITVFDALKRRFQCATVQLDFQLPIRFNLSYVS---EANE-PERPIIIHRAILGS 566
303277979 497 ALNKSGKE--WKLNPGDGAFYGPKIDITVFDALKRRFQCATVQLDFQLPIRFNLSYVT---ENNE-PARPIIIHRAILGS 570
302816171 477 ALNAHAKP--WQMNEGDGAFYGPKIDIQVSDALNRKFQCATIQLDFQSPIRFKLSYSA---EDEAKIERPVIIHRAILGS 551
302816173 369 ALNAHAKP--WQMNEGDGAFYGPKIDIQVSDALNRKFQCATIQLDFQSPIRFKLSYSA---EDEAKIERPVIIHRAILGS 443
302820128 477 ALNAHAKP--WQMNEGDGAFYGPKIDIQVSDALNRKFQCATIQLDFQSPIRFKLSYSA---EDEAKIERPVIIHRAILGS 551

224002114 673 VERMFAVLCEHYGGKWPLWLSPRQVMVVPIHKDWNDYSQGVRDKLHAEGFYADVDLSKATFQKKVRNAQVEQYNFQLVVG 752
145348874 561 VERMFAILTEHFAGKWPYWLSPKQVMIVPISEASRDYCYEVKRQLRKAGHFAEVDVTDRKMQKKVREAQLDQFNYILVCG 640
159476198 547 VERMFAILTEHFAGKWPFWLNPRQVMVVPISENSVEYAFTVRKELRSAGLHCDVDSTDRKMQKKVREAQLAQYNYILVVG 626
168064726 567 VERMFAILLEHYAGKWPFWLSPRQCIVCPVSEKFTHYAVEVRDAINAAGYFCEADVTDRKLQKKIREAQLAQFNYILVVG 646
242033449 621 VERMFAILLEHYNGKWPLWLSPRQAIVCSVSSGSVEYAKQVLATLHEAGFHADIDASDRTIQKKVREAQLAQFNYILVVG 700
255071725 567 VERMFAILTEHFAGKWPFWLSPRQVMIVPISEQSRDYAHEVRSVLRKEGFYCEVDDSDRKMQKKVREAQLEQWNYILVVG 646
303277979 571 VERMFAILTEHFAGKYPYWLSPKQVMLVPISEASREYALEVKKQLRKAGHHAQVDETDRKMQKKVREAQLEHWNYILVVG 650
302816171 552 IERMFAILLEDNAGKWPFWLSPRQAIVLTISEKFKDYAEEVRAKLHAAGFEVDVDVSDRKVDKKVREAQMAHYNYLLVVG 631
302816173 444 IERMFAILLEDNAGKWPFWLSPRQAIVLTISEKFKDYAEEVRAKLHAAGFEVDVDVSDRKVDKKVREAQMAHYNYLLVVG 523
302820128 552 VERMFAILLEDNVGKWPFWLSPRQAIVLTISEKFKDYAEEVRAKLHAAGFEVDVDVSDRKVDKKVREAQMAHYNYLLVVG 631

224002114 753 EAEVKNDTVNIRTR-DNKVEGEKKVDELIEYLKQLRAEYK 791
145348874 641 ESEKANETVNVRTR-DNKVHVIIRGETAITRFRKT----- 674
159476198 627 EAEKTAQTVNVRTR-DNVVHGMFKLSDVRELMVLERNTRS 665
168064726 647 EEETSKKQVNIRTR-DNVVHGTKSVTELLADFQKETAEYR 685
242033449 701 AQEAETGNICVRVR-DNADLATMSVDGFVTRLKEEIAAFR 739
255071725 647 EGEKTNRTVNIRTR-DNVVHGEHKLEEGLLETLLEERRTK 685
303277979 651 EGEKTNRTVNVRTR-DNVVHGEVKLEELMTVLNEERSTKS 689
302816171 632 AMEQEKGEVRTKA-------ACL----------------- 647
302816173 524 AMEQEKGEVNVRTRgSKGQRGCITIEKLIAEFQDLVANYT 563
302820128 632 AMEQEKGEVRTKA-------ACL----------------- 647