1BU8,2PVS,1GPL,1RP1


Conserved Protein Domain Family
Lipase

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pfam00151: Lipase 
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Lipase
Statistics
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PSSM-Id: 395099
Aligned: 12 rows
Threshold Bit Score: 341.344
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1BU8_A   1 KEVCYGHLGCFSNDKPWAG-MLQRPLKIFP-WSPEDID--TRFLLYTNENP--NNYQKISaTEPDTIKFSNFQLDRKTRF 74  Norway rat
P27657  17 KEVCFDKLGCFSDDAPWSG-TIDRPLKALP-WSPAQIN--TRFLLYTNENQ--DNYQKIT-SDASSIRNSNFKTNRKTRI 89  Norway rat
P50903  17 GEVCFDRLGCFSDNKPWAG-TSERPRKGLP-WDPSAIN--VRFLLYTNENP--NNYQRIT-ADSSVIRSSDFKTDRKTRF 89  domestic guinea pig
Q02157  17 LEVCYERLGCFGNRIPWSGgTLERPFSTLP-STPKIVN--TRFLLYTNENP--NNFQEIS-ADASTIRGSNFRTDRKTRF 90  rabbit
2PVS_A   1 KEVCYGQLGCFSDEKPWAG-TLQRPVKLLP-WSPEDID--TRFLLYTNENP--NNFQLITgTEPDTIEASNFQLDRKTRF 74  human
1GPL_A   1 xEVCYSHLGCFSDEKPWAG-TSQRPIKSLP-SDPKKIN--TRFLLYTNENQ--NSYQLITaTDIATIKASNFNLNRKTRF 74  domestic guinea pig
1RP1_A   1 KEVCYEQIGCFSDAEPWAG-TAIRPLKVLP-WSPERIG--TRFLLYTNKNP--NNFQTLLpSDPSTIGASNFQTDKKTRF 74  dog
P02844  97 SQIRGYIVGERGQKIEFNLnTLVEKVK----RQQKFGDdeVTIFIq---------------GLPETNTQVQKATRKLVQA 157 fruit fly
P97535  14 GSLLWLSIGRSGNVPPTTQ-PKCTDFQSANlLRGTNLK--VQFLLFTPSDP--GCGQLVE--EDSDIRNSEFNASLGTKL 86  Norway rat
Q29524  12 svWLQSLTVS------RGGlV-AADRITRG-KDFRDIE--SKFALRTPEDTaeDTCHLIP-GVTESVANCHFNHSSKTFV 80  sheep
O46559  18 QSSTHGQSLR------PEPfGRRARVTATK-KTLLETE--TRFLLFKDKANk--GCQIRL-HHADTLQECGFNSSLPLVM 85  rabbit
P07867  18 QSSACGQGVG------TEPfGRNLGATEER-KPLQKPE--IRFLLFKDESDr-LGCQLRP-QHPETLQECGFNSSHPLVM 86  Norway rat
1BU8_A  75 IVHGFIDKG-----------------EDGWLLDMCKKMFQV--EKVNCICVDWRRGSRTEYTQASYNTRVVGAEIAFLVQ 135 Norway rat
P27657  90 IIHGFIDKG-----------------EENWLSDMCKNMFKV--ESVNCICVDWKGGSRATYTQATQNVRVVGAEVALLVN 150 Norway rat
P50903  90 IIHGFIDKG-----------------EENWLADLCKALFQV--ESVNCICVDWRGGSRTLYSQASQNIQVVGAEVAYLIN 150 domestic guinea pig
Q02157  91 IIHGFTDKG-----------------EENWLSNLCENLFQV--ETVNCICVDWKGGSRTTYPQATQNIRIVGAEVAYLVG 151 rabbit
2PVS_A  75 IIHGFLDKA-----------------EDSWPSDMCKKMFEV--EKVNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQ 135 human
1GPL_A  75 IIHGFTDSG-----------------ENSWLSDMCKNMFQV--EKVNCICVDWKGGSKAQYSQASQNIRVVGAEVAYLVQ 135 domestic guinea pig
1RP1_A  75 IIHGFIDKG-----------------EENWLLDMCKNMFKV--EEVNCICVDWKKGSQTSYTQAANNVRVVGAQVAQMLS 135 dog
P02844 158 YQQRYNLQPyettdysneeqsqrsssEEQQTQRRKQNGEQDdtKTGDLIVIQLGNAIEDFEQYATLNIERLGEIIGNRLV 237 fruit fly
P97535  87 IIHGFRALGt----------------KPSWINKFIRALLRA--ADANVIAVDWVYGSTGMYFSAVENVVKLSLEISRFLS 148 Norway rat
Q29524  81 VIHGWTVTGm----------------YESWVPKLVAALYKRe-pDSNVIVVDWLSRAQQHYPVSAGYTKLVGQDVAKFMN 143 sheep
O46559  86 IVHGWSVDGl----------------LESWIWQMVAALKSQpaRPVNVGLVDWISLAHSHYAVAVRNARLVGQEVAALLQ 149 rabbit
P07867  87 IIHGWSVDGl----------------LETWIWKIVGALKSRqsQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLL 150 Norway rat
1BU8_A 136 VLSTEMGYSPENVHLIGHSLGAHVVGEAGRRLEG----HVGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVIHTDSAPI 211 Norway rat
P27657 151 VLKSDLGHPPDNVHLIGHSLGSHVAGEAGKRTFG----AIGRITGLDAAEPYFQGTPEEVRLDPTDAQFVDAIHTDAAPI 226 Norway rat
P50903 151 FLQSQLDYPPSSVHIIGHSLGSHAAGEAGRRTNG----AIGRITGLDPAEPYFQYTPEIVRLDPSDAQFVDVIHTDGNPI 226 domestic guinea pig
Q02157 152 TLQSSLGYSPSNIHVIGHSLGAHAAGEVGRRTNG----TIGRITGLDPAEPYFQGTPEIVRLDPSDAQFVDVIHTDAAPM 227 rabbit
2PVS_A 136 ALSTQLGYSLEDVHVIGHSLGAHTAAEAGRRLGG----RVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPI 211 human
1GPL_A 136 VLSTSLNYAPENVHIIGHSLGAHTAGEAGKRLNG----LVGRITGLDPAEPYFQDTPEEVRLDPSDAKFVDVIHTDISPI 211 domestic guinea pig
1RP1_A 136 MLSANYSYSPSQVQLIGHSLGAHVAGEAGSRTPG-----LGRITGLDPVEASFQGTPEEVRLDPTDADFVDVIHTDAAPL 210 dog
P02844 238 ELTNTVNVPQEIIHLIGSGPAAHVAGVAGRQFTRqtghKLRRITALDPTKIYGKPEERLTGLARGDADFVDAIHTSA--- 314 fruit fly
P97535 149 KLL-ELGVSESSIHIIGVSLGAHVGGMVGHFYKG----QLGRITGLDPAGPEYTRASLEERLDSGDALFVEAIHTDTD-- 221 Norway rat
Q29524 144 WMADEFNYPLGNVHLLGYSLGAHAAGIAGSLTNK----KVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGS 219 sheep
O46559 150 WLEESAPFSRSNVHLIGYSLGAHVAGFAGSYISGk--hKIGRITGLDAAGPLFEGTSASDRLSPDDATFVDAIHTFTREH 227 rabbit
P07867 151 WLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGk--rKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREH 228 Norway rat
1BU8_A 212 iPYLGFGMSQKVGHLDFFPNGGKE-MPGCQKNILSTIVDINGIWEGTQnFVACNHLRSYKYYASSIL--NPD-GFLGYPC 287 Norway rat
P27657 227 iPNLGFGMSQTVGHLDFFPNGGME-MPGCQKNILSQIVDIDGIWEGTRdFAACNHLRSYKYYTDSIV--NPT-GFSGFSC 302 Norway rat
P50903 227 iPNLGFGMSQTVGHLDFFPNGGLQ-MPGCQKNILSQIVDIDGIWEGTRdFAACNHLRSYKYYIDSIT--NPK-GFAGFSC 302 domestic guinea pig
Q02157 228 vPNLGFGMSQTVGHLDFFPNGGKE-MPGCQKNVLSQIVDINGVWEGTRdFVACNHLRSYKYYADSIV--NPN-GFAGFSC 303 rabbit
2PVS_A 212 vPSLGFGMSQKVGHLDFFPNGGKE-MPGCKKNVLSTITDIDGIWEGIGgFVSCNHLRSFEYYSSSVL--NPD-GFLGYPC 287 human
1GPL_A 212 lPSLGFGMSQKVGHMDFFPNGGKD-MPGCKTGI------------------SCNHHRSIEYYHSSIL--NPE-GFLGYPC 269 domestic guinea pig
1RP1_A 211 iPFLGFGTSQQMGHLDFFPNGGEE-MPGCKKNALSQIVDLDGIWEGTRdFVACNHLRSYKYYSESIL--NPD-GFASYPC 286 dog
P02844 315 ---YGMGTSQRLANVDFFPNGPSTgVPGADNVVE-------------------ATMRATRYFAESVRpgNER-NFPSVAA 371 fruit fly
P97535 222 ----NLGIRIPVGHVDYFVNGGQD-QPGCPAFI-----------HAGYsYLICDHMRAVHLYISALE--NTC-PLMAFPC 282 Norway rat
Q29524 220 -PGRSIGIQKPVGHVDIYPNGGTF-QPGCNIGEALRVIAERGLGDVDQ-LVKCSHERSVHLFIDSLL--NEEnPSKAYRC 294 sheep
O46559 228 -MGLSVGIKQPVGHYDFYPNGGSF-QPGCHFLELYKHIAQHGLNALSQ-TIKCAHERSVHLFIDSLL--HPSmQSTAYQC 302 rabbit
P07867 229 -MGLSVGIKQPIAHYDFYPNGGSF-QPGCHFLELYKHIAEHGLNAITQ-TINCAHERSVHLFIDSLQ--HSNlQNTGFQC 303 Norway rat
1BU8_A 288 SSYEKFQQNDCFPCPEE---GCPKMGHY-ADQFEGKTATVEQTVYLNTGDSGNF 337 Norway rat
P27657 303 SSYNVFSANKCFPCGSE---GCPQMGHY-ADKYPGKTKELYQKFYLNTGDKSNF 352 Norway rat
P50903 303 DSYSSFSSNKCFPCATG---ECPQMGHY-ADKFPGKTKENFQNFYLNTGDKSNF 352 domestic guinea pig
Q02157 304 ASYTAFSANKCFPC-SN---GCPQMGHY-ADRFSRKTDGVGQTFYLNTGDSSNF 352 rabbit
2PVS_A 288 ASYDEFQESKCFPCPAE---GCPKMGHY-ADQFKGKTSAVEQTFFLNTGESGQF 337 human
1GPL_A 270 ASYDEFQESGCFPCPAK---GCPKMGHF-ADQYPGKTNAVEQTFFLNTGASDNF 319 domestic guinea pig
1RP1_A 287 ASYRAFESNKCFPCPDQ---GCPQMGHY-ADKFAVKTSDETQKYFLNTGDSSNF 336 dog
P02844 372 SSYQEYKQNKGYG-------KRGYMGIA--TDFD-----LQGDYILQVNSKSPF 411 fruit fly
P97535 283 ASYKAFLAGDCLDCFNPfllSCPRIGLVeRGGVKIEPLPKEVRVYLQTTSSAPY 336 Norway rat
Q29524 295 NSKEAFEKGLCLSCRKN---RCNNMGYE-INKVRAKRSS---KMYLKTRSQMPY 341 sheep
O46559 303 SDMDSFSQGLCLGCTKG---RCNTLGYH-IRQEPLSKGK---RLFLVTQAQSPF 349 rabbit
P07867 304 SNMDSFSQGLCLNCKKG---RCNSLGYD-IRRIGHVKSK---TLFLITRAQSPF 350 Norway rat
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