5DD7,6XEP,3C9R,2YXZ


Conserved Protein Domain Family
ThiL

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COG0611: ThiL 
Thiamine monophosphate kinase [Coenzyme transport and metabolism]
Thiamine monophosphate kinase is part of the Pathway/BioSystem: Thiamine biosynthesis
Statistics
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PSSM-Id: 440376
Aligned: 846 rows
Threshold Bit Score: 109.851
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5DD7_A         9 M---AEFSIIDQYFNR--QSHP-DVA--LGi--GDDSALIt-pPp---------nQQLVICADTLVAGRHFPLETSPHAI 68 
BAJ51181       7 L---GEKRLIQYLVEHld-wPR-DGL--LPp--GDDAAAFwf------------tgQLVASVDTLVWETDVPPRMTFRQV 65 
AFU57405       4 L---DEKEIIRIFADKl------------GiadLDDVVLLg--------------KGVVFKTDMLVASTDVPDSMEAWQI 54 
ALI34687       4 F---NEKQILNIIISKfgNNN---MEpyIG---KDDISIMpldSlnsssnefndnKFLAITCDMLVEHTDVPPKMTFEQI 74 
CUR52495       1 MknpNEIEIIKTFQSQfgKKSK------Fq---ADDIEVLki-----------gnVKFIVKSDMLVQSTDMPIGMRLDEV 60 
WP_012308700   1 Mr--pERELIDEIIGLvsE-DPyGLLr-LG---RDDASARrl-----------neGIYVFKMDMVSSSTDLLPGMSLRQL 62 
WP_020962346   9 L---REDIIIDWVTSQl------------Gi-qKNDAAFFe--Hn---------eTKIVINVDSFESTIHLYPfVPLRIA 61 
WP_075054707   6 L---DEKEIIRIFSQAl------------GiadLDDVAKVg--------------RNLVFKADMLVASTDVPPQMSPWQV 56 
WP_048104675   4 L---NEKEIIKIINSK-----H------VS---SEDVEIFnl-----------anKQCAVCVDTLVESTDIPKGSKLSDI 55 
WP_103287148   7 V---GERRVIEIISSSigKRc------------YDDVELVrv-----------nnIEVALKCDMLVEGTDVPRGMEPWQI 60 
5DD7_A        69 GWKSVAVNLSDIAAMGAKPHSILLAISLPQ-VDhewLEGFSQGIYDCCNQFGVALIGGDTTQGP--HLTITVTAMGWIEt 145
BAJ51181      66 GWKAVTAAVSDLAAKGARPKYILLSLALKPsTEfseFLDLVNGAQEASKKYGAAIVGGDINESS--SHSISVTALGSSE- 142
AFU57405      55 ARKSIVSCVSDLAAKGVRPHAAMISLGLPEnRTrpyVEGLAEGFAIASKEFGVKIVGGDTNKAN--ELVIDCSMVGFASs 132
ALI34687      75 ARKSVVSSVSDLVSKGIMPKAALISLGLPKsLKnseISRLINGLSLASKEFGIDIVGGDINESK--EIIIDCCMFGSLSs 152
CUR52495      61 ARKSMVSCVSDFSCKGVKPIFATIALAIPRnFTqkmINALAIGFRRSSKEFGVDIIGGDTNEGK--ELVIEVSMFGTINr 138
WP_012308700  63 AKKCVVANFSDVASKGARPLLFMCSLGLPRgMRdeeFVSIFEGFEEAMRKYGTYLVGGDLGESE--ELIISGFAFGRVE- 139
WP_020962346  62 GRRAATGSLSDVLVKGAVPRGILTAIRAPAtMSiesYKEFYSGIIDVAKRYDLRILGGDTDIAEtgSLRADIVVFGFAK- 140
WP_075054707  57 ARKSIVACASDLAAKGARPVAAMISLGLPEeITrtyVEELARGFQIASREFGVKIVGGDTNAAR--DLVIDCSMIGMTAa 134
WP_048104675  56 SRKSIVSSVSDFAAKGIIPKFCIISVTLPKtISkkqVQELSKGFSKACKEFKIQLLGGDTNQGT--EISIHVVLFGNVK- 132
WP_103287148  61 ARKSIVAPVSDMASKGVRPLYALTSLALPKgLDegyVRSIARGFRRAEMEFNIKIVGGDTNEGK--ELIIDCCMLGMVEe 138
5DD7_A       146 -GKAVLRSGAKVGDYVCVSGQIGDAAYGLQHLGH-----------SLQQRLDYPT-PRCKLGEELK--GLASSMIDVSDG 210
BAJ51181     143 --KLLSRVGASPGDMLATTGLFGKTFTGLHAAMNsrp-----cerELAEAVYSPV-ARVDEGVALAtcGGVSACIDSSDG 214
AFU57405     133 -GKIPTRKGAGPGDFVVVSGMFGLPPAGLAILMQntvat-gafkkQAAESVLVPK-PRQRFGLALAk--YFSSSIDSSDG 207
ALI34687     153 vANIPRRNGACIGDYVVVSGIFGYSSSGLKILMNnlscpdsyfrrRSVDSVLIPS-PSYEFGIYIAr--YFSSSMDSSDG 229
CUR52495     139 --KIPSRGGARTGDIIITSGPFGYSSAGLKIILDgyktn-pqatkRFRRAIFRPN-PRLDFGLKAAk--YFSSSMDSSDG 212
WP_012308700 140 -GRLVGRGGSRPGDIVMTTGSFGLTWLGFKHLLEglelp-eglrrRALKSVYEPE-ARVEEGIIISn--YATSTVDSSDG 214
WP_020962346 141 -GKIANRWGAKPGDLLAVSGRVGLSSILYYYYRQnsvnc--sitrEMLEEYGWGQlPKPAEWLALKe--NVHAAIDNSDG 215
WP_075054707 135 dNRMPKRGGAKPGDVVVASGKFGYPASGLAVLLKgaraq-gafraAAVDSALEPK-PRQAFGITLAr--YFSSSIDSSDG 210
WP_048104675 133 --KYTKRKGAKIGDVICTTGAFGYTAAALDIILKkkkss-kafsaKSKNLFFRPK-ARLEFGHKLTn--YTSSSIDSSDG 206
WP_103287148 139 gSRFVKRSGASNGDLILVSGPFGYTKAGLKILLEgakae-ptfraRAIRSVLMPK-PRLRFGLMLAr--YATSTMDSSDG 214
5DD7_A       211 LAQDLGHILKASKVGARLILEKLPVDPVLQQI---EEQQRWQYALAGGDDYELCFTITPQNYEKLlqkq--ldvKITMIG 285
BAJ51181     215 LAESLHQLSEANDVGFIVD--SLPLDSSAQRYcvdNNLDPVEAVFYGGEEYELVFTVKPGWGDVVekalarlgkEVVWIG 292
AFU57405     208 LAISLYELASQSRVNIAIE--NVPAAEGVEKFaqeNGLDAHELVFHGGEEYEIVATIPRSKLKQAmaaarkagtALHVIG 285
ALI34687     230 LASSLHELSKQSGVNLLIEEDKIPIPPRLKEFlsiNNLDFHDLVFYGGEEYNIVGTISEKNLVEVseilkvrhlKLYIIG 309
CUR52495     213 LAITLNDMSHQSRKKFVIT--NMPTGNDVIKFvrqNKMSLENIVFCGGEEYEIVSTVHQEDLQKIrnlakkmkiPLAEIG 290
WP_012308700 215 LYWSLKELSRASGNGFLIE--ELPLDEEVGLFl---GGDSISAAFHGGEEYEIVFTLREEDVAKVrdeltvlgvEPIKIG 289
WP_020962346 216 LALSLHYLSEASGVKLIID--HIPLHPLAEECip-kERILDEVLYNSGEEYNFIFTIPAEEESTVak------lGFTVIG 286
WP_075054707 211 LAASLHEIAVQSNVDIKVDYDAA-RADGVQEFaraNGLDAHELVFHGGEEYEIVATMPKSLLPRAratakkagcDLHIIG 289
WP_048104675 207 LSSCLNELSNQNKKKFLIT--KIPTNKDVIEFsnkNNTSLNRLVFDGGEEFELVFTVMPENLKKIhalakknkiSIFEIG 284
WP_103287148 215 LAYTLHEMSNASGKRFIIEHK--PIGRGVERFardNSLSIDDLVFYAGEEYEIVATIRREHLDEVmsisrltgcNAMIIG 292
5DD7_A       286 QIVE-QTK-LTFEHLg-SdyPlqiHgyQH 311
BAJ51181     293 SVNQ-GRG-VYFq---gK--PverRgwQH 314
AFU57405     286 RVQR-GAGdVFVg----Kr-LlenRgyVH 308
ALI34687     310 KVVS-GIGrVFVLTSngNkkLlknKgyAH 337
CUR52495     291 YVTN-GKN-VVLVNRdgSk-VikrCgwTH 316
WP_012308700 290 RVVE-GGG-IRLRAGn-EliEvpeGgwEH 315
WP_020962346 287 KVEE-GRG-VYFrd----giEikrigwvg 309
WP_075054707 290 SVKKkGTGrVTs----gRr-LlenRgyLH 313
WP_048104675 285 YVYK-GKG-VFF-DDgnSsfKiedNgwQH 310
WP_103287148 293 RVHE-GTG-VYIKDEygEr-ElkgYgwEH 318
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