2XV7


Conserved Protein Domain Family
PDGF

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smart00141: PDGF 
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Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
Platelet-derived growth factor is a potent activator for cells of mesenchymal origin. PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer. Members of the VEGF family are homologues of PDGF.
Statistics
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PSSM-Id: 197537
Aligned: 11 rows
Threshold Bit Score: 96.7212
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2XV7_A        20 TQCSPRETAVEVASELGKST--N--TFFKPPCVNVFRCGGCCNEESLICMNTSTS--Y--ISKQLFEIS--------VPL 83  human
NP_001020281  49 SFCRPIETLVDIFQEYPDEI--E--FIFKPSCVPLMRCGGCCNDESLECVPTEEF--N--ITMQIMRIK--------PHQ 112 sheep
EDL02853      50 SYCRPMEKLVYILDEYPDEV--S--HIFSPSCVLLSRCSGCCGDEGLHCVPIKTA--N--ITMQILKIP--------PNR 113 house mouse
AAB30462      50 SYCRALERLVDVVSEYPSEV--E--HMFSPSCVSLLRCTGCCGDEDLHCVPVETA--N--VTMQLLKIR--------SGD 113 human
EAW74222      28 ATCQPREVVVPLTVELMGTV--A--KQLVPSCVTVQRCGGCCPDDGLECVPTGQH--Q--VRMQILMIR--------YPS 91  human
CAG46695     129 TQCMPREVCIDVGKEFGVAT--N--TFFKPPCVSVYRCGGCCNSEGLQCMNTSTS--Y--LSKTLFEIT--------VPL 192 human
P52584        34 SECKPRPIVVPVSETHPELT--S--QRFNPPCVTLMRCGGCCNDESLECVPTEEV--N--VSMELLGAS--------GSG 97  Orf virus (stra...
P97946       114 TQCSPRETCVEVASELGKTT--N--TFFKPPCVNVFRCGGCCNEEGVMCMNTSTS--Y--ISKQLFEIS--------VPL 177 house mouse
P12919        99 AECKTRTEVFEVSRRLIDRT--NanFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQlrL--VQVRKIEIVr------kRPV 168 domestic cat
AAP88590      94 AVCKTRTVIYEIPRSQVDPTsaN--FLIWPPCVEVKRCTGCCNTSSVKCQPSRVH--HrsVKVAKVEYV--------RKK 161 house mouse
P52585        44 SGCKPRDTVVYLGEEYPEST--N--LQYNPRCVTVKRCSGCCNGDGQICTAVETR--N--TTVTVSVTGvssssgtnSGV 115 Orf virus NZ7
2XV7_A        84 TS-VpeLVPVKVANHTGCKCLP 104 human
NP_001020281 113 SQ-H--IGEMSFLQHNKCECRP 131 sheep
EDL02853     114 DP-Hf-YVEMTFSQDVLCECRP 133 house mouse
AAB30462     114 RP-S--YVELTFSQHVRCECRP 132 human
EAW74222      92 SQ----LGEMSLEEHSQCECRP 109 human
CAG46695     193 SQ-GpkPVTISFANHTSCRCMS 213 human
P52584        98 SN-G--MQRLSFVEHKKCDCrp 116 Orf virus (strain NZ2)
P97946       178 TS-VpeLVPVKIANHTGCKCLP 198 house mouse
P12919       169 FK----KATVTLEDHLACKCET 186 domestic cat
AAP88590     162 PKlK--EVQVRLEEHLECACAT 181 house mouse
P52585       116 ST-N--LQRISVTEHTKCDCIG 134 Orf virus NZ7
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