4B7C


Conserved Protein Domain Family
CurA

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COG2130: CurA 
NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
Statistics
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PSSM-Id: 441733
Aligned: 422 rows
Threshold Bit Score: 378.633
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4B7C_A         6 QINRQYQLAQRPS-G-LPGRDTFSFVETPLGEPAEGQILVKNEYLSLDPAMRGWMNDARSYIPPVGIGEVM-RALGVGKV 82 
WP_011647259   5 ETLQQIVLAQYCD-G-VPKPSDFRLETAPLPEPKDGQFRVAHVWCSVDPGTRSRLSGGDSYAAALPLGKPI-DGFSVGVV 81 
WP_012109974   3 TKAKRWVLASRPE-G-KPTAENFRLDDMTLPDIGEHEILIRTEFHSVDPGMRGRLSG-DSYTAALPVGETI-DSAMVGVV 78 
WP_012464326   1 MKNKQIILVKKPE-G-MIDESHFAAVFTDVPAPKDGEVLVKNRYVSIDPYLRLLTEEPATFSRGVQVGSRM-ESWSVGEV 77 
WP_047855335   3 AINRQFLLARRPE-G-RLRESDFDYREAPVPEPGPGEVLTRTVYLSIDPANRAWMFPDPTYRPPIGLGEVV-AGFTLNEV 79 
WP_008248102   3 NINRRYVLKERPRfQ-VPTAKCFRLEEEAAPEPGEGEFRIRTTWLGMDPNLFSKVKKVSDQARPIPIGAVM-YGATVGRV 80 
WP_083684344  16 FQNQTIRVAKQVApG-SLEADAFELRANAVPELKDGEILVRIIYISIDAGSRAQFDDRADYVFKTAVGQMPgSSGAVGEI 94 
WP_089420249   1 MNNRQIVVQSLPD-G-TLTEDHFALQEAEMPAVGDGEVLLKTILMSIDAANRSWMQG-ATYRDAVKAGDVM-ATYSICEV 76 
WP_106473782   2 TGNRQITVADLPD-G-ALEPRHFALAEAPMPEPAEGEVLLRTILMSIDAANRSWMQG-ATYRDAVRAGDAM-PTYALCEV 77 
WP_117293975   2 TQNRRIVLAERPR-YiTPTANCFQLQSGALPQPGEGQLLVRTTWLSLDPYLHGRLKRTTAQAEPVKVGDVM-VGATIGRI 79 
4B7C_A        83 LVSKHPGFQAGDYV-NGALGVQDYFIGEPK--G-F-YKV-DP----SRAPLPRYLSALGMTGMTAYFALLDVGQPKNGET 152
WP_011647259  82 DASSNPDWPVGTKV-FCAGGWKTHSIQSGK--G-FiGKVmDV----PGVPLSAWIGVLGVPGLTAWFGMKDVARFKEGDA 153
WP_012109974  79 EASNNEKFKVGDRV-TGGFGWVTHAVSNGR--G-V-QVL-APemfhGALRPTAAIGVLGIPGLTSYFGLLELGQPKEGDT 152
WP_012464326  78 LESKSDAFKPSQFV-VGYLGWQEYGLSEAR--D-L-RRI-DP----SLAPLPAFLGVLGMPGITAYFGIFRYGKPQAGQT 147
WP_047855335  80 VDSRDARFRPGDLV-ECEGGWQDYAVLPAD--A-L-HTL-EP-----RKPLSHWMSVLGVTGKTAYFGMLEVGKIRAGET 148
WP_008248102  81 DISNHPDFSVGDLV-HGLWGWQDYFISNGA--G-I-FSV-DN----DISRPSYCLGALGATGFGAYLVVNDVLAVKNGDT 150
WP_083684344  95 VASRDPQWPIGELVaTGHTRWQRYQKFRPGreQfL-VRI-DP----AHGPLPLHLGALGLVGFTAYIGVFDIGQPAPGET 168
WP_089420249  77 VETNSPRVAVGDIV-AAEAVWADYVVRPAH--K-V-EKL-PK-----VDQLSHLISVYGIAGKTAFHGLVSVGKPMAGET 145
WP_106473782  78 IESRSDRLAPGDIV-ATESVWADYVTRPAR--L-V-LKQ-PE-----IRPLSHLMSVYGIAGKTAFHGLVNVGRPIAGET 146
WP_117293975  80 EQSRHPDYKAGDLV-RGFWGWQDYAAVEPK--R-V-HKL-DP----CLQQPSLALGTLGLPGFGAWLALRVLSPVKAGET 149
4B7C_A       153 VVISGAAGAVGSVAGQIARLKGC-RVVGIAGGAEKCRFLVEELGFDGAIDYKN-EDLAAGLKRECPKGIDVFFDNVGGEI 230
WP_011647259 154 VLVTSAAGPVGATAGQLAKGWGAsKVVGVAGSDEKCRWLVSEAGFDAAINYKTaSDLSGAIAAEFPKGVDVLFDNVGNAM 233
WP_012109974 153 VLISSAAGPVGATAGQIAKMKGC-RVVGIAGSKEKCDYVK-GLGFDACFSYRG-ADLRAAIKEHCPDGVDIYFDNVGAEM 229
WP_012464326 148 VLISAASGTVGMTAGQLAKMHSC-RVIGIAETEEKCRYLVEELHFDRAINISQ-RSLIEGLKEDAPEGIDLYYDNVGGET 225
WP_047855335 149 VLVSAAAGAVGSFAGQIAKLHGC-RVLGIAGGPEKCRWLTEELGFDAAIDYQS-GDLSERLAACCPEGVDVYFDNVGGAV 226
WP_008248102 151 VFCSAATGALGQMVGQISHLKGG-ATYGSAGTDEKCRLAVSKLGYTDCFNYKS-ENFERMLSDRIDGGIDAMVVSAGGQT 228
WP_083684344 169 FLVSAAAGATGALAGQFARIAGA-RVVGIAGGAAKCAFVRDELGFDDCVDYKQ-GGLREAIARACPAGVDVYYENVGGEI 246
WP_089420249 146 IVVSAAAGSVGGFVGQIGKALGC-RVVGIAGGAEKCKWVVDELGFDACVDYRD-AGLFKALRAECPDGIDVYFDNVGGTV 223
WP_106473782 147 ILVSAAAGSVGGYVGQIGKALGC-RVVGIAGGAEKCAWVVDHLGFDACVDYRA-PGLYKALRAACPNGVDVYFDNVGGET 224
WP_117293975 150 VVIGTATGALGQTAGQIAKLMGC-RVVGIAGGPEKCRLATERLGYDACVDHRQ-RDFADHLRAACPKGIDVYVETIGGKA 227
4B7C_A       231 LDTVLTRIAFKARIVLCGAISQYNNK-EAV-RGP----ANYL-SLLVNRARMEGMVVMDYA--Q-RFPEGLKEMATWLAE 300
WP_011647259 234 VDTVLPLMALNGRICISGQVADYNLKpEET-PGI----VHTK-PFITHRVNMQGLVVFDFA--R-GFPEALGSMAKMIAS 304
WP_012109974 230 LDAAILNMKEHGRIVVSGQVSEYNRA-EDElVGI----RNVT-RFITHRLRMEGLVVFDYF--K-RFREAQAEMAGWIHE 300
WP_012464326 226 LDNALLFLRKNSRVVICGMISQYNVK-TP--YAL----KNFE-RLHSARATLKGFIVADLM--S-QWPEALSKLERWVKE 294
WP_047855335 227 FQAALFRMKTHGRIVCCGVMSILDTD-TPP-PRL----LGVPgLLAIRRLRLEGFIVLDYY--G-RRRQAEQALAGWVAE 297
WP_008248102 229 FDATFPLMAPGGRIAVCGLMALYSMT-QLP-VTPdrsfMILN-EILLKRLTVKGSMVLDMLntD-RHVEFKREMKSWIAQ 304
WP_083684344 247 QKAAFANMNDFGRVALCGQVAQYSGG-GEA-PGP-----NLM-TLVLKRLTVRGFLAMDHM--A-RHHEFIARASAWYRE 315
WP_089420249 224 LETVLALMNDKGRIACCGAISQYDTK-AP--TGP----RNLPgLVVVKRLRMEGFIVMDFA--D-DDAKAIRALQTWVRN 293
WP_106473782 225 LETALAVMNERGRVVCCGAISQYDTA-TP--TGP----RNLPgLVVVKRLRMEGFIVMDFA--D-RDATALRALQTWVAE 294
WP_117293975 228 TSAVLRLCNLQARVTVAGLMSMITRQ-GSA-EDAlladDFLN-EVVNRRLSIRGLVTFDHI--EtHFGLFQDEMLAWIGD 302
4B7C_A       301 GKLQSREDIVEGLETFPETLLKLFSGENFGKLVLKV 336
WP_011647259 305 GALKIQEDRFEGIAEIPEAFCGLFRGENSGRRVVKV 340
WP_012109974 301 GKLQYTEDVSEGIEGSAAAFIGLFEGENLGRRLIEV 336
WP_012464326 295 KKLKHKENIFHGLENAPKALHSIFTEAPIGKTVVEV 330
WP_047855335 298 GRLKVREDIIDGLQNAPRALMGQLHGANIGKRMIRV 333
WP_008248102 305 GVVRPVEFITEGLENAPDALRAVFDGENIGKSVVHV 340
WP_083684344 316 GRLKHHATITPGLENMHEAINSLVEGRNLGKQLCQV 351
WP_089420249 294 GQIKVTEDIVEGLENAPKALIGLLAGDNKGKRMVRV 329
WP_106473782 295 GRIRVSEDIVEGLENAPGALIGLLAGDNRGKRMVRV 330
WP_117293975 303 GRVKPVEHVVDGLEHAPSALQGLFEGRNLGKLIVKV 338
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