Conserved Protein Domain Family
FOP_dimer

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pfam09398: FOP_dimer 
FOP N terminal dimerization domain
Fibroblast growth factor receptor 1 (FGFR1) oncogene partner (FOP) is a centrosomal protein that is involved in anchoring microtubules to subcellular structures. This domain includes a Lis-homology motif. It forms an alpha helical bundle and is involved in dimerization.
Statistics
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PSSM-Id: 312785
Aligned: 4 rows
Threshold Bit Score: 87.994
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6IQF6        48 K-TPLVNENLKKSLNTKD---GRLVAGLITDFLQVFNLDFTLAVFQPEISTLNGLDSREVLSKELGISESEVNKNSPLLL 123 zebrafish
XP_001630402  47 K-IPLTNGNLKKFISTSE---GRLVAGLVREFLEFFELDFTIAVFDPESNFSDKYQGRNNLANELNLPDSDSAATKPLLA 122
Q5ZJ24        43 R-PPLCHENL-------------LINELIREYLEFNKYKYSASVLTAEAGQPEVPLDRQFLVKELNIVEDANGKSVPLLY 108 chicken
A0CY94        45 KiSPFFSEN-KKVQSIKEletGRELLELIKEFLKFYEMSYTNSIFSSEANLREEI-NRDAISKRLQINIED--KNKPLLH 120 Paramecium tetr...
Q6IQF6       124 ELVKR 128 zebrafish
XP_001630402 123 EVVRH 127
Q5ZJ24       109 GIISH 113 chicken
A0CY94       121 FVLVQ 125 Paramecium tetraurelia
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