3DWL


Conserved Protein Domain Family
P21-Arc

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pfam04062: P21-Arc 
ARP2/3 complex ARPC3 (21 kDa) subunit
The seven component ARP2/3 actin-organizing complex is involved in actin assembly and function.
Statistics
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PSSM-Id: 461152
Aligned: 87 rows
Threshold Bit Score: 208.892
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3DWL_E         1 MPAYHSSFLSL-TDVPTTGNIAMLPLK--TKFR--GPAYPA-------DESQMDIIDECIGLFRANCFFRNF--EIKGPA 66 
XP_001761158   1 -mVYHSSLKVD-DEIQQACSCPILPLK--SHIR--GPAPTA-------EAGSMDIIDEAINYFRANVLFRKF--EIKGPA 65 
XP_002975315   1 -mVYHSSFKDE-SGAGQACGCPLLPLR--TPIK--GPAPLA-------DPGQFDIIDEAINFFRANVLFRKF--EVKSSA 65 
XP_009395285   1 -mVYHSSFVDE-EGITKACGCPLLPLK--THIK--GPAPVS-------DQDKIDIVDEAITFFRANVFFKNF--DIKSPA 65 
Q4DBS1         1 ---mHSRWNGY--EESSLLGCGVYPLRrtSRLTppGPAPRMdemieegEEEPQDIVDEAFYFFKPHMFFRNF--PIKGAG 73  Trypanosoma cruzi
EFC48429       1 MPAYHSSFKDA-KC-EVYCGTAILPLK--TKVK--GPAPKEl------DENKEDIIDEVLKFFKSNMLFRSY--QVESPA 66 
XP_002955200   1 -mAYHSLFNDSgDRYRLCCGCPLIPLN--VSSA--APSDa--------DGTTLDPIDEAIELFRPNSLFKSF--DIRGPG 65 
XP_647903      4 sgAYHSELDKD--IVQKAGNFPLMQFK--TKVKv-NPKFLL-------KGDDMDIVDEAITYYKANVFYKNFdmSI-CEA 70 
XP_003292692   1 -mVYHSNFNDEsAQYRLVGNIPILPLK--TNHK--GPAPKA-------DANSGDIIDEALDLFKANILFRNF--EVQGNG 66 
XP_004366095   1 -mVYHSSFNDEsAGFRTIGNFPILPIK--TAHK--GPAPKPq------DPNAVDAIDEALDLFKANILFRTF--EVQGNG 67 
3DWL_E        67 DRTLIYGTLFISECLGRVN---GLNYRDAERQLNSLALENFSIPGSAGFPLNALYAPP-LSPQDAEIMRTYLTQFRQELA 142
XP_001761158  66 DKLLVYLTLYINMALKRIEa--CKTEADGVKAIINLGLEKFPIPGEPGFPLGGLFTAP-QTREEGDLLRNYFKQVREETS 142
XP_002975315  66 DKLLIYLTMYINMALKRIEt--CKSEAEGIKVIINLGLEKFPIPGEPDFPLGGLFTTP-GSPQEADLFRNYLKQLREETS 142
XP_009395285  66 DKLLIYLTFYINVALKRLEg--CRTLAVGTKAIINLGLEKVPVPGEPGFPFPGLFSVP-QSQDEAELFRNYLKQIREETS 142
Q4DBS1        74 DRVILYLTMYLHECLKKIV---QLKREEAHSVLLNYATMPFASPGEKDFPFNAFF--PaGNEEEQEKWREYAKQLRLEAN 148 Trypanosoma cruzi
EFC48429      67 DRTLIYLTMYTHFLLKHTEnkkTTKKADADKLYFQLSEEALPGPGDSSFALIAFYDKP-RDTNEKKQWDSYMRQAKEELG 145
XP_002955200  66 DKLLVYLILFINSCLRQRKp--PPSREEARALLFATAHDRFPLPGQAGFPLGALMLAP-ASREEEETIRSYLRQCREEAG 142
XP_647903     71 DKLLVYLIFYIQSLLLKFN---GHTKVECDKMAYSLAIENFALPGDGKFCLGGIVEPL-KASEK-EVVRQYMTAIRNETG 145
XP_003292692  67 DRVLIYLTLYITKCLLKIA---NMSKADADKALFLLAQEQFSIPGEASFPLGGLVNVP-NTRDAQDTLRQYFTQLRIEIG 142
XP_004366095  68 DRVLIYLTLYITKCLLKIA---NLSKADAEKQLFTMAQEQFSIPGETSFPLGGMITIP-AARDAADNIRQALTQLRLETG 143
3DWL_E       143 YRLLSHVYa------tEKD-----HPSKWWTCFSKRRFMNKAL 174
XP_001761158 143 GRLMEKVYr-------QNG-----TPNKWWLAFAKRKFMNimm 173
XP_002975315 143 GRLMGRVYr-------PNG-----SPNKWWLAFAKRRFMNill 173
XP_009395285 143 GRLLNCAYr-------PNG-----TPNKWWLAFAKRKFMNivv 173
Q4DBS1       149 ARLIEKVFlf----peKDG-----TGNKFWMAFAKRPFLASs- 181 Trypanosoma cruzi
EFC48429     146 LRLAKLIFk-------EDG-----VADKYWMQFSKRKFLGKAf 176
XP_002955200 143 RRLLERLYaapgaaggEGGtavaaAPNRHWLAFANRRFLDRTi 185
XP_647903    146 LRLTQAVF--------KNDp---tKCDKWWMCFNKRKFLNKTi 177
XP_003292692 143 VRLTQRVYa------vDPA-----RPNKWWMCFSKRKFLNKAL 174
XP_004366095 144 IRLVQRVYa------tDPA-----RPNKWWMAFSKRKFLGKAi 175
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