2Z4R


Conserved Protein Domain Family
DnaA

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TIGR00362: DnaA 
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chromosomal replication initiator protein DnaA
DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 273037
Aligned: 85 rows
Threshold Bit Score: 371.092
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2Z4R_A         2 KERILQEIKT-RVNRKS-WELWFSSFD-VKSIEGNk--VVFSVGNLFIKEWLEKkyysVLSKAVKVVLGN-DATFEITYE 75  Thermotoga mari...
WP_011076827  11 YLIIKKEIEK-EFQNENfYNNYVLDSS-IFKIKDEn--VYILVKNDFVKEVFTNeykeIFEEYFSIKMNS-NLNVFFITK 85  Mycoplasma pene...
WP_010869493   7 FKSLLKKHYEkTIGF---HDKYIKDIN-RFVFKNNv--LLILLENEFARNSLNDn--sEIIHLAESLYEG-IKSVNFVNE 77  Mycoplasma geni...
WP_010875043   7 FKLLLKKQYEtTLGF---YDKYIKNLK-RFALKNNv--LFVIVDNEFARETLNSn--pDIVGLASKLYDD-IRAVRFVNE 77  Mycoplasma pneu...
WP_011576992   8 EKRILELAKQ-QVSPIE-YENYLSQLK-YNPNASKsdiAFFYAPNMVLCSTITAkysaLLKEILSQNKVGmHLAHSVDVR 84  Helicobacter ac...
WP_011412285   8 WDVILNELSK-IYSDEV-FKETFSNIKkIKQIEEK---IIISVETEFIKNKIYKmyfeKIKEINKLKFEE-KIIIEFVSE 81  Aster yellows w...
WP_002892013   3 PSQILENLKK-ELSENE-YENYLSNLK-FNEKQSKadlLVFNAPNELMAKFIQTkygkKIAHFYEVQSGN-KAIINVQAQ 78  Campylobacter j...
WP_023846698  12 WDACLRILQD-IVDERA-YRTWFLPII-PVSIEGDt--LTLQVPSQFFCEFLEGnfveQLRTVLGRVIGP-NASLQYNAL 85  Porphyromonas g...
WP_005798188  10 WNRCLEIIRD-NVPEST-YKTWFVPIV-PLKYEDKt--LIVQVPSQFFYEFLEDkfvdLLRKTLYKVIGD-GTKLMYNVL 83  Bacteroides
WP_011137974   3 GDTTLKQLKD-EISTLE-YERYIKQLR-YDEEASRtdlAVYIAPNQFIANWVKTkygeRLAHLFELSTGI-RPKIEIRLG 78  Wolinella succi...
2Z4R_A        76 ------------AFEPHSSYSEPLVKKR------AVLLT---------------------------------------PL 98  Thermotoga mari...
WP_011076827  86 ee---------kDINKELPTIEEKPKTL------EINPT----------------------------------------L 110 Mycoplasma pene...
WP_010869493  78 q-----------DFFFNLAKLEENSRDT------LYQNS---------------------------------------GL 101 Mycoplasma geni...
WP_010875043  78 q-----------DFFINLAKLEEDNRET------LYQSS---------------------------------------GL 101 Mycoplasma pneu...
WP_011576992  85 -------------IEVASKVHVSDHSNI------NYKATk-------------------------------------sSI 108 Helicobacter ac...
WP_011412285  82 nnkkncnfdnekKHFENIKKELKNETEIffckieNNDEFknnkhfrkneikqiengyndninveienrkisfnkynygNT 161 Aster yellows w...
WP_002892013  79 -------------SAKQSNKSTKIDIAH------IKAQSt--------------------------------------IL 101 Campylobacter j...
WP_023846698  86 vdnsspkypgtvTLAGCADGGQAAEQFD------VNLLHrhmpnaath----------------------seaqdfdtQL 137 Porphyromonas g...
WP_005798188  84 vdkssgatvnqeSTTRSTAIPQSGLPRV------DERKApgllrap-------------------------avqdldpHL 132 Bacteroides
WP_011137974  79 ------------SLKKDVKSSSPKAGVS------KGQKSt--------------------------------------IL 102 Wolinella succi...
2Z4R_A        99 NPDYTFENFVVGPGNSFAYHAALEVAKh--pGr--YNPLFIYGGVGLGKTHLLQSIGNYVVQNe-pDLRVMYITSEKFLN 173 Thermotoga mari...
WP_011076827 111 DSRFTFENYTIGMFNKNAFKAASLFLEe---Nn-nWKTLLIYGSTGLGKTHLLHAVGNKFVQLf-pQKNLMYIQTEDFLE 185 Mycoplasma pene...
WP_010869493 102 SKNYTFQNFVISEGNKRAYEAGVRLAEt--qDn-eFSPLFIYGETGLGKTHLLQAIGNEKFRNf-pNARVKYVVSSDFAQ 177 Mycoplasma geni...
WP_010875043 102 SKNFTFKNFVVGDGNRRVYEAGVRISEt--qDa-dFSPLFIYGETGLGKTHLLQAIGNDKFFHf-pNAKVKYVVSSDFAQ 177 Mycoplasma pneu...
WP_011576992 109 KDSYTFENFVVGSCNNTVYEIAKKIAQs--dTp-pYNPVLFYGGTGLGKTHILNAIGNHALEK---HKKVVLVTSEDFLR 182 Helicobacter ac...
WP_011412285 162 NPKYSFDNFVVGKSNNFAFKISKKIAEe--kKv-tTNPLYIFGKSGIGKTHLIQAIGNHILKNthsSKKVLYVKADGFIE 238 Aster yellows w...
WP_002892013 102 NPSFTFDSFVVGDSNKYAYGACKAITHkdklGk-lYNPIFVYGPTGLGKTHLLQAVGNASLEM---GKKVIYATSENFIN 177 Campylobacter j...
WP_023846698 138 NSRLNFRNFYQSECNYVARSVAEAIAAs--pGntpMNPFFIYGASGVGKTHLCHALGLRVREMh-pRLKVLYVSSHLFEM 214 Porphyromonas g...
WP_005798188 133 NPNYNFETFIEGYSNKLSRSVAEAVAEn--pAktvFNPLFLHGASGVGKTHLANAIGTRIKELy-pDKRVLYVSAHLFQV 209 Bacteroides
WP_011137974 103 NPSFTFDSFVVGNSNRFAYEVSQNVAKk--qGi-aYNPLLIYGGTGLGKTHLLNSIGNYNVAK---GKSVIYVTSEQFLN 176 Wolinella succi...
2Z4R_A       174 DLVDSMKE----GKLNEFREKYRkKVDILLIDDVQFLIGKTGVQTELFHTFNELHDSGKQIVICSDREPQKLSEFQDRLV 249 Thermotoga mari...
WP_011076827 186 KIYKAISEg--gTKVEEFKNSFD-NVDLLLIDDIQFLNNKEKLNEIFFNIFNRLNSKNKYIVMTSDKLPTSLK-IDDRMI 261 Mycoplasma pene...
WP_010869493 178 EVVDAFYQr--dKGIEKLKKNYE-NLDLVLIDDTQIFGRKEKTLEILFNIFNNLVLNKKQIVLVSDKAPDELIDIDARMI 254 Mycoplasma geni...
WP_010875043 178 EVVNAFYQkekdQGIEKLKAAYE-SLDLLLIDDTQIFGKKEKTLEILFSIFNNLVSKGKQIVFVSDKTPDELANIDPRMV 256 Mycoplasma pneu...
WP_011576992 183 DFLKHLNN----RSMDSFKEKYR-HCDFFLLDDAQFLQGKPQLEEEFFHTFNELHANNRQIVLISDRSPKNIAGLEDRLK 257 Helicobacter ac...
WP_011412285 239 EFTNQLRK----AKMEDFNEKYR-DIDLLLVDDIQIMAGATRTQMEFFKLFDYLYLNQKQIVITSDKQASELKNIMSRLT 313 Aster yellows w...
WP_002892013 178 DFTSNLKN----GSLDKFHEKYR-NCDVLLIDDVQFLGKTDKIQEEFFFIFNEIKNNDGQIIMTSDNPPNMLKGITERLK 252 Campylobacter j...
WP_023846698 215 QFTTAARM----GTINDFIAFYQ-QVDVLIIDDIQWLIGKKKTQLAFFQVFNHLYMLGKQIVLTSDKPPVDLNGMEERLV 289 Porphyromonas g...
WP_005798188 210 QYTDSVRN----NTTNDFINFYQ-TIDVLIIDDIQEFAGVTKTQNTFFHIFNHLHQNGKQLILTSDRAPVLLQGMEERLL 284 Bacteroides
WP_011137974 177 DYLYHIRN----NTMDRFRDKYR-ACDYLLIDDVQFFGGKPQIQEEFFHTFNELHNKNKQIVLTSDKTPKQIAGLEERLK 251 Wolinella succi...
2Z4R_A       250 SRFQMGLVAKLEPPDEETRKSIARKMLEI----EHGELP--EEVLNFVAENVDDNLRRLRGAIIKLLVYKETTG-KEVDL 322 Thermotoga mari...
WP_011076827 262 SRFNSGLSIKINKPDTESIKKIIIENIKK----SRIKNPfsNLAIEFIALRFNSDIRTLEGVLNKIYFHLLDNV-DPNEI 336 Mycoplasma pene...
WP_010869493 255 SRFKSGLLLKIEKHNLSSLCEILTVKLKE----KDPNIQitNEARHDAAQISGNDVRALNGIATKLLFFAKTSKqNLINT 330 Mycoplasma geni...
WP_010875043 257 SRFKSGLLLKIEKHNLSSLCEILAVKLKE----KDPNIQitNEAREKAAQISGNDVRSLNGIATKLLFYVKTTKqNLINN 332 Mycoplasma pneu...
WP_011576992 258 SRFEWGITAKIMPPDLETKLSIVKQKCQL----NKIILP--EEVMEYIAQHISDNIRQMEGAIIKISVNANLMN-APIDL 330 Helicobacter ac...
WP_011412285 314 SRFEAGLMVDIQSPDFNHRLNILKKKILEfepqNTLKIK--KDVLDLIASSFVNNVREMEGALLRLLNYAQTFG-YDIDI 390 Aster yellows w...
WP_002892013 253 SRFAHGIIADITPPQLDTKIAIIRKKCEF----NDINLS--NDIINYIATSLGDNIREIEGIIISLNAYATILG-QEITL 325 Campylobacter j...
WP_023846698 290 TRMAGATCVKIERPDLKLRREILQQRTLQ----SGVRLD--ESVLNFIAENVCDNVRELEGTLVSLITNSVVVG-KEIDL 362 Porphyromonas g...
WP_005798188 285 TRFKWGMVAELEKPTVELRKNILRNKIHR----DGLQFP--SEVIDYIAENVNESVRDLEGIVISIMAHSTIYN-KEIDL 357 Bacteroides
WP_011137974 252 SRFEWGMVSDIQPPELETKINIIKKKCEF----DGIYLS--NEIISYIATNMDNNIREIEGIIIKLNAYANLMN-QEITL 324 Wolinella succi...
2Z4R_A       323 KEAILLLKDFIkp----------nRvkAMDPIDELIEIVAKVTGVPREEILSNSRNVKALTARRIGMYVAKNYLKSSLRT 392 Thermotoga mari...
WP_011076827 337 -INEEKIRSIIesdsdyeivsnlvQ----INPDIIIESICLGYGVDKKSVISKKRNKQFSFVRKVCMYVLREKINLSYNE 411 Mycoplasma pene...
WP_010869493 331 ENLKEILFEEFek---------fhK--KSFDPYLLIENVCRRFNVPMDSVLSENRKAELVRVRDVCNYLLRQKYNMQFQQ 399 Mycoplasma geni...
WP_010875043 333 DNLKEILFEEFek---------fhK--KSFDPYLLIENVCRRFNVPVDSVLSENRKAELVRVRDVCNYILREKYKMQFQQ 401 Mycoplasma pneu...
WP_011576992 331 NLAKTVLEDLQkd----------qA--EGSSLENILLAVAQSLNLKSSEIKVSSRQKNVALARKLVVYFARLYTPNPTLS 398 Helicobacter ac...
WP_011412285 391 NIANEALELLIksk--------ksVsyDEDVLEKIKLVVSNFFNISVRDLMSKKRQQKYTFPRHIAIYLIKELKDIPYNI 462 Aster yellows w...
WP_002892013 326 ELAKSVMKDHIke----------kK--ENITIDDILSLVCKEFNIKPSDVKSNKKTQNIVTARRIVIYLARALTALTMPQ 393 Campylobacter j...
WP_023846698 363 TFAKRIVRQAVrl----------eK--KEVTIECIQQAVSRVFQVQIEQMKSKSRKQDIVQARQVVMFLSKKHTAQSLSA 430 Porphyromonas g...
WP_005798188 358 DLAQRIVRKVVrc----------eT--KAVTIDDIINVVCKHFDLESSAIHTKSRKREVVQARQVAMYLAKTHTDFSTSK 425 Bacteroides
WP_011137974 325 QFAKNVLKEQIke----------eR--ENITLENIIEVVSKELNVKPAEIKSKGRSKNIANARRIVIFLARTLTPNSMPS 392 Wolinella succi...
2Z4R_A       393 IAEKFN-RSHPVVVDSVKKVKDsLLKGNKQLKALI-DEVIGEI 433 Thermotoga maritima
WP_011076827 412 IGSFFSnRNHATVLEAIKDVET-KVKSDEDLKAFL-DNIMSKF 452 Mycoplasma penetrans
WP_010869493 400 IGKIFK-RSHSSVLMAVKRVAK-MIENDSSLRDVI-TSLVI-- 437 Mycoplasma genitalium
WP_010875043 402 IGKIFK-RNHSTVVAAVKRVAK-MIEKDDSLQDII-TSLVI-- 439 Mycoplasma pneumoniae
WP_011576992 399 LAQFLDlKDHSSISKMYSSIKK-MLEEKNPFVLSLkEEIKNRL 440 Helicobacter acinonychis
WP_011412285 463 VGSFFK-RNHSAVFKAYQKIKK-NSQSDYELKKSL-ELILKKI 502 Aster yellows witches'-broom phytoplasma
WP_002892013 394 LANYFEmKDHTAISHNVKKITE-MIENDGSLKAKI-EELKNKI 434 Campylobacter jejuni
WP_023846698 431 IGELMGgRNHATVLHGCRCVTN-EMEMNASFRSSV-ERAEQLI 471 Porphyromonas gingivalis
WP_005798188 426 IGKFIGnKDHATVLHACKTVKG-QCEVDKGFRSDL-ENIETLL 466 Bacteroides
WP_011137974 393 LAQFFGmKDHSSVSKAMKTVKT-EIEEDANFKMVI-EELKNKI 433 Wolinella succinogenes
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