Conserved Protein Domain Family
NupO

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COG3845: NupO 
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism]
Statistics
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PSSM-Id: 443055
Aligned: 686 rows
Threshold Bit Score: 458.337
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_109946      5 AFRMENICKSFdnGRVKANVDVNLTVYENTVHTLLGENGAGKSTLTSILFGLYQPDSGKIFIGEEEVHFKSSKDAVQHKI 84 
WP_012615742   2 QITVEHLTKRF--GAVCANDQLSISFASGQIHGVLGENGAGKSTLMKLLAGYLRPDEGQIRFNGVVQRLRGPGDALAAGV 79 
WP_015774282   1 MIVLRDISKHY--GRVRANDSISLTLEPGRIYALVGENGAGKSTLMRILAGHTVPDSGVITLRGEEHPGLTPAMAARLGV 78 
WP_012236184   2 RIEIERVAKRF--GPVKANDGVSLTIQAGAVHGLLGENGAGKSTLLRILGGLLRPDAGRLLFDGRPVALASPADALAAGV 79 
WP_015164824   2 KVELRGISKNF--GKVRANQDISITIPAGAIVGLLGENGAGKSTLVKILSGFISSDRGEIWLDDRLVQLKSPAHAVRSGI 79 
WP_015405664   2 DVEFQHISKHF--GSVSALTDVSLTAHSGTIHGIIGENGAGKSTLMKILTGYQSKSSGTILIGGQDVKLDNPRQAARLGI 79 
WP_114592375   1 MLEVIDVHKRY--GTVKANDGVAFTVQPGALHGLVGENGAGKSTIVGIVSGARRADAGRIRLDGVDLDMSGPRDGLAAGI 78 
WP_116223632   2 HIQLKNIHKYF--GSVHANNDVSLTIEPGQILGLLGENGAGKSTLMKILSGLICKDSGEILINGEEQDLKSPADALRLGI 79 
WP_095042722   2 RVELRDIRKYF--GQVKANDGINLTFEPGKIYALVGENGAGKSTLMKILSGYQPPTGGEILLDGRPVRFHSPADALAKGV 79 
WP_087861103   2 NIEFKKINKHF--GAVHANVDIDFSINSGTIYGILGENGAGKSTLMKILSGFIQPDSGEILLDGQQVRIDSPADAIKFGI 79 
NP_109946     85 GMVHQHFKLVDNYTVLDNIILGNESSFsipftn-------gklklPLLHRKAS-EAKIQAMMERYDLHVNLHQKVSRLTV 156
WP_012615742  80 GMVHQEPLDIPAFTVIENLLCAAPPGV-------------------FRSRRAA-EMVLRELSAQLGFTVDPTARIEQLTV 139
WP_015774282  79 GMLYQDPLDFPALPVWENFRLSGPSR----------------------NRTQV-VDRLGELSNHLGVCFLPDEPVASMTV 135
WP_012236184  80 GVLHQEPLDFPPLTVLESYLVARPRAAgaggvarsplpgrggaagVFLPRRAA-REELLALAARFGFSVDPDEHVARLTL 158
WP_015164824  80 GMLHQDPLDFAPLTVLDNFMTGQSNRFg----------------rFWLDRKTA-KRQLKQLGQQYGFTLAADRLVAKLSV 142
WP_015405664  80 GMLYQEPMDFPPLSVLENFSLGTPER----------------------KDQKL-RLALLSLATRFGFHLDPDRCVGRLTV 136
WP_114592375  79 GLLHQDPMVLGPMTVLENFLLGSH---------------------GHLSRAEG-RRQLAATCDRLGFELPPDAVARTLTV 136
WP_116223632  80 GMLHQDPHDFPSMTIREDLQIWDQRS-------------------GRANHSAVdWQALMKIQEDLGFNLDLDGSVGELTV 140
WP_095042722  80 GMLYQDPLDMPPFRVIDNYLLGRDNR-------------------TRLDYKAA-RAELDALAARYGFSIDANATIDSLSM 139
WP_087861103  80 GMLHQDPLDFPPMLVIDNFIVGQGGK-------------------FLLSHKTV-IKEFQELQDQFGFALDPYTYVDTLTV 139
NP_109946    157 GQQQRVEILKVLFRDSDILIFDEPTAVLSDQEIKSFLNIIKNFK-KMGKTIVLISHKLNEIKEVAETATILRQGHSVGTF 235
WP_012615742 140 GQRQQVEIMRLLLCGAQVLILDEPTTGITAAQARALFAALRQIA-AEGRTVLFVSHKLEEVAELCDTVTVLRNGRVVPPG 218
WP_015774282 136 GERQLLELLRLLDLGATTLILDEPTTGITPEQKRDLFGLLSRLArQEGHTVILVTHKLSEALEMADAIFVMRQGRLEARL 215
WP_012236184 159 GERQQIELLRLLSLGVRALLLDEPTTGISGAQQEALFSALRRLK-ADGKAIVLVSHKLSDVEALCDRVTVLRQGKVAGEA 237
WP_015164824 143 GERQQLEILRLLSLGVNTLILDEPTTGISLPQKLLLFATIRELA-AAGKSIIFVSHKLEDVETLCDRVVVMRQGRIVGEL 221
WP_015405664 137 GERQQIELLRLIHCKTRILILDEPTTGISPAQKEVLFPALKRLA-ADGMTILLVSHKLEEVASLCDELTVLRHGRTTHHS 215
WP_114592375 137 GERQQLEMARLLAAGARVLILDEPTTAISADQRELLFAALRRLAdEEGLSVVYVTHKLEELAELCHRVTVMRAGRVVGER 216
WP_116223632 141 GERQQLELARLLWLGVELLILDEPTTGISASQQEILFSALKKLA-GQGKTIIFVSHKLEEVKELCSRAVVLRKGCLIGER 219
WP_095042722 140 GERQQLELVRLLAGGAQVLILDEPTTGISAEQKGVLFDSMRVMTrEEGKTVILVSHKLEEVQELCFYAYILRRGKLAGDQ 219
WP_087861103 140 GERQQLEILRLLWLGAGVLILDEPTTGISVQQKEKLFAALKVLA-KQGKTIIFVSHKLEDVEIMCDQVAILRKGQLVGEV 218
NP_109946    236 QIK-------------------------------------DTsIDEMARLMMGKELKETK-NNT-QfTAKGEP------- 269
WP_012615742 219 QLPm------------------------------------PQpQEYLLSLMFGDAGTASSvYRPlP-TIDAPP------- 254
WP_015774282 216 TP--------------------------------------PYdSEELVRRMFGDTAAQST-DSA-L-PEIGQSr------ 248
WP_012236184 238 EM--------------------------------------PAgADRLVALMFGEALAPQE-RSP-E-EDGGAPlaplerl 276
WP_015164824 222 NLKqnfalnikdiinispqepglvnsvansssastsdastSEqIDQLVEMMFGRELAVA--NKP-E-TAQADP------- 290
WP_015405664 216 AA--------------------------------------PFyLPELLTAMFGAIPEQTD-KIP-K-RSTGEP------- 247
WP_114592375 217 DL--------------------------------------PVsDAELVELMFGSSPE-LG-ERE-A-VTVGAP------- 247
WP_116223632 220 EA--------------------------------------PFdENDLVKLMFGRQIT-RT-RTA-H-AGTRDV------- 250
WP_095042722 220 EL--------------------------------------PClNEQLVEMMFGQAPQ-RS-RRP-D-FALGQP------- 250
WP_087861103 219 VA--------------------------------------PYnINQLVEMMFGKQIV-IN-EPK-S-RVTDEI------- 249
NP_109946    270 -------------------VLKVENLHLYlnqnwfykliarwnqkrinqlQKqgkpaktlwLKSwleglaaiektprfir 330
WP_012615742 255 -------------------VWELKHVTVRsgm---------------------------lqLVD---------------- 272
WP_015774282 249 -------------------RVTLAETVFA---------------------GPky------hLGP---------------- 266
WP_012236184 277 pepsggaepsggaepsggaALALEGVAFG---------------------DHrl------dVRI---------------- 313
WP_015164824 291 -------------------SLRLEAIEVR---------------------SDrl------nLSI---------------- 308
WP_015405664 248 -------------------ILVLEDVEAA---------------------GErl------gLQQ---------------- 265
WP_114592375 248 -------------------LLRLHGVGAL---------------------DGst------tVAD---------------- 265
WP_116223632 251 -------------------CLSVQKLNIE---------------------DFri------aIEN---------------- 268
WP_095042722 251 -------------------VLELQDATIA---------------------TYql------tIPP---------------- 268
WP_087861103 250 -------------------VFELENFSVE---------------------QYpi------tIEN---------------- 267
NP_109946    331 givnnlgfgsqqvfdkgISFEIHKGEIFAIAGVEGNGQNQLIDLICGLEKAAPKKVFFNGF--------DI--SRYSIRK 400
WP_012615742 273 -----------------LNHRFTAGRIIGLAGLDGSGQQVLLRLLAGQLVPERGQVLVNGR--------DL--SGAGPLV 325
WP_015774282 267 -----------------LNLSAAPGEIIGLAGLDGSGQELFLRGLCGLDRMAAGSLTLNNA--------AH--ARTHFKT 319
WP_012236184 314 -----------------AHLAVRRGEVIGLAGLEGSGQRLLLRACAGLLRARRGRVAVGGA--------DL--TGRPYPA 366
WP_015164824 309 -----------------KQFTAQQGEVIGLAGLEGNGQRLLLLLCAGLLTANSGHIYLGDT--------NM--TNRTYQQ 361
WP_015405664 266 -----------------CNTIVTEGEVIGLAGLDGAGQSTFLRLAAGLTTPIEGTVKLFGE--------NLprTINASLQ 320
WP_114592375 266 -----------------ADLVVHAREVVGLAGMEGSGQRSLLRLAAGVLAAEAGTIELADAgadsdglvDV--TRESPRR 326
WP_116223632 269 -----------------VNFDLYAGEVIGLAGMEGSGQRQFLQALAGMKQPSSGHILFGDE--------DL--FGKNCYD 321
WP_095042722 269 -----------------INLSVRAGEIFGFAGLEGSGQRLVMQACGGLIPVAGGRVRLGGQ--------DV--TGWRYHR 321
WP_087861103 268 -----------------VHFRMRAGEVIGLAGMEGSGQDVLLRACAGLLRPVSGRVIVNQK--------DL--TGKTYHD 320
NP_109946    401 RINAGIGFVLEDRHKYGLILDQTVRFNAVN-NQIDRkq-fsSWNFLNQMQIAVYTNQIVDKFDVRgAVQGtAIVRLLSGG 478
WP_012615742 326 FRQAGIEYLPADRLHDGMIGALSLTDHFAL-LQRNG-------VLIDRRRAEELARQAIAEYQIK-ATPI-TPIAALSGG 395
WP_015774282 320 LRREGVHFVPADRMSQALFPDLSIRDHILL-AFPKH----------AARLEEFHQSQCVERFDLR-AHPD-TPAKALSGG 386
WP_012236184 367 FLRAGVGYLPADRRREGLIAGLSIEEHVAL-RAPRP------GLFLRPREIRRAAERAIEALRIR-GRPD-TPVERLSGG 437
WP_015164824 362 YLRTGVSYIPADRLAEGLVGGLSIQEHFAL-RSIDTsgstlGRTFINWRNTLAKTHRAINTYNIR-GFPT-SRVEQLSGG 438
WP_015405664 321 AQRLKTSFIPADRLEEALFAEISISDHFSL-RRSGN------TFWHSTKTSRRLTQEAIAQFSIK-GQAE-DAAGDLSGG 391
WP_114592375 327 RRAMGLEFLPADRLAEGLVPGLTVAEHADL-AGAVPvrsgwRRFWRDDDAAVAVAERAIDTYRIK-ATPT-STPEQLSGG 403
WP_116223632 322 YQKRGIFYVPSARMEEGLVPGMTLEEHYIL-SDCEK------RVFIDSKKSHKVTEDRIQRFNIK-GRAV-TFSEELSGG 392
WP_095042722 322 LQDYGVGYVAAGRLEEGLVAGLSLTEHLVL-ARPGQ------RFFVDWKENQAEMGERIKTYQIV-GRPE-TTADALSGG 392
WP_087861103 321 FMRHGVAFLPASKLEEGLVPELTLAEHFTLvTEHKK------QLFIDKPFFQNKTKQKIDDYRIV-GQPE-TPVEALSGG 392
NP_109946    479 NQQKLIIGReLTKQNELLVFAQVTRGLDVGAISFIHQKILDAKKQNnAILLVSYELDEILAIADTIGVINKGNLLEVNKr 558
WP_012615742 396 NQQRAMLAL-IPPDARGILAEQPTRGLDVASARAIWSRLQARRDDGcCVVFASPDLDEIMEYSDEVIVCFAGRIGPPIPr 474
WP_015774282 387 NQQRLLLSL-IPDDAPLLLMEHPTRGLDAGSSRQVWEHLRKRCAAGaTLFFFSPDLDEVIEHSHRVLIFFDRALVADVPr 465
WP_012236184 438 NQQRTQLAL-LPAGLALLLLEQPTRGLDLASARWVWEQLLARCRAGaALLFASSDLDELMRYSDRLLVFSGGRVSPPVGv 516
WP_015164824 439 NQQRTQLAL-LAENLNLLLMEHPTRGLDIDSAQWVWQQMVERCRQGtTILFISADLDEIMQWSDRVLVFSGGQVTEPIAt 517
WP_015405664 392 NQQRLLLAL-LDPQSRLLLLENPTRGLDIRSGQWVWNYLRSELSPEtTIIFSSPELDEILYYSDRILVFHDGDIVLDSAi 470
WP_114592375 404 NQQRLLLSL-VGDDVDVLLMEHPTRGLDVASAEWVWDLLTARADAGaGIVFSSSDLDELRRRADRILVCFAGRIIASLDa 482
WP_116223632 393 NQQRLLLSL-LQDPAKVLLLENPTRGLDIESTNWIWSILRERCQAAtSIIFSSADLDELTFYADRILVFFSGRISEPLDs 471
WP_095042722 393 NQQRLLFSL-LNAPLKLLLLEHPTRGLDVRSADYIWQLLYQRRQDGtAILFISADLDEIIEHSDRIAVFSGGVMSRVLDa 471
WP_087861103 393 NQQRASLSM-LKDSLSIILLEHPTRGLDIESAMYMWDKLKERCAGCtSIFFISADLEEIIRYSDRILVFFSGHVSEPQDs 471
NP_109946    559 dvMTRERIGKLIM 571
WP_012615742 475 alLSAGRLAELIG 487
WP_015774282 466 hnASVEILGALMA 478
WP_012236184 517 adLTLDRLGRMIG 529
WP_015164824 518 knLTVDRLGQMIG 530
WP_015405664 471 lnTSHDVIAAAMM 483
WP_114592375 483 adADPDTLGHLIG 495
WP_116223632 472 agLDEERLGRMIG 484
WP_095042722 472 raTTAEELGHLIG 484
WP_087861103 472 skISLEQLGQMIG 484
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