Conserved Protein Domain Family
creatininase

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TIGR04448: creatininase 
creatininase
Members of this family are creatininase (EC 3.5.2.10), an amidohydrolase that interconverts creatinine + H(2)O with creatine. It should not be confused with creatinase (EC 3.5.3.3), which hydrolyzes creatine to sarcosine plus urea. [Central intermediary metabolism, Nitrogen metabolism]
Statistics
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PSSM-Id: 275241
Aligned: 11 rows
Threshold Bit Score: 399.794
Created: 10-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_04668836   10 QMTWQEIEQCIK-E-GYGIILPIGSTEQHGPALPISTDAICAREVSLGAAENTKMLVAPTIQYGYRSRPLSGGGATFPGT 87  Clostridiales b...
WP_013946433   9 EMSWTTYQKRIE-D-GAIILLPTGATEQHGPHLPMGTDALLATAVAADVAKQIEAVVAPVLSFGYKSQPKMGGGNHFCGT 86  Hyphomicrobium
WP_012315116   9 ELTWPEYAQKVA-S-GSTIFLPVGALEQHGHHMCMEVDVLLPTALCKAVAREVDGLVLPALAYGYKSQQKSGGGNHFPGT 86  Pseudomonas putida
WP_012695975   9 ELDSFTYRAAAHdE-GRVLLIPVGAIEQHGPHMSMNVDVLLPTKVSEIVAGQINGLVAPPIMYGYKSQQRSGGGHHLCGT 87  Laribacter hong...
WP_013167045   9 ELSWPEFKAKVA-A-GAPVLLPLGSTEQHGPHLPLNVDVVLPTGVCERVAREVGGLVAPTVNYGCKSMPRSGGGEQFPGT 86  Starkeya novella
WP_011913141   7 QLSWVDYERRVR-E-GAVVFLPCGATEQHGPHLPLGTDALLASAISADVAARVGGLVAPALSYGYKSQPKCGGGQHFCGT 84  Pseudomonas stu...
WP_013350048   8 ELDAQTYAEHVA-RtGSTIIIPAGATEQHGPHMPLGVDAMLSRSIAEAVAQLTGALVAPALCYGYKSQPRSGGGNHRVGT 86  Arthrobacter ar...
WP_011563451  11 EMTWPEVREAIE-R-GAGVFLPVGSTEQHGYHLPLATDVILPTELALAVADELDFLVAPPVAYGYRSRPLSGGGQGFVGT 88  Rubrobacter xyl...
WP_011100059   9 NMTWKEFEKKKD-N---VIILPIGSTEQHGPHLPTCVDTVLANGFAYRIAEKIDGVVAPALSYGYKSKPLSGGGPLFPGT 84  Clostridium tetani
WP_013168384   8 DLTWYDFAERVK-E-DPIVFLPIGSVEQHGPHLPLATDTLLPLAVAQQVADRVGGLVAPPVAYGYKSQPKSGGGNHFPGT 85  Starkeya novella
WP_011067911   9 HMTWPEFKEAKT-R---PVIVPIGSTEQHGQHLPIGTDAVLATRVAEDLAERIDGTVLPTLSYGYKSKPLSGGGPLFPGT 84  Bifidobacterium...
ZP_04668836   88 TNLSGHTLICVIEDILEEFARMGFKKVVVLSMHMENQNFIYEGSYLVSRRH-----PDMKIMVMESaFGDIQ-ENIMDVL 161 Clostridiales b...
WP_013946433  87 TSLDADTLAHVLRDVIKEFARHGARQLVLINGHYENMMFTIEGVDLARRELaymgiHDFEVMRLEY-WDFTK-RETLDKI 164 Hyphomicrobium
WP_012315116  87 TSLDGATLTHTIQDIIRELARHGARKLVLMNGHYENSMFIVEGIDLALRELryggiTDFKVVVLSY-WDFVNaPAVIEEL 165 Pseudomonas putida
WP_012695975  88 TSLDGQTLTDISHTLIREFVRHGFRRFAFVNGHYENNYFLIEGIDLALRELrwegiPDVKVMMLSY-WDFVD-ESTIEKL 165 Laribacter hong...
WP_013167045  87 LSLDANTFALVVRDVIRNLVRQGVRRLVVVNGHYENCWPSVEGLDLALRELksegvDDLVVMRLEY-WDFAQ-RATLDRL 164 Starkeya novella
WP_011913141  85 TSLDGATLSALVRDAVREFYRHGVRRLVLVLGHYENQWFVAEGIQLALRDLgp--dAGLEVMRLEH-WDFCH-EQTLTDI 160 Pseudomonas stu...
WP_013350048  87 TSLGGTSLSLMVEDVVASFISQGFDNVVLLNGHFENYQFLYEGVDNAVAKTrt-agSTARAILLSY-WDFVD-ENTLAKV 163 Arthrobacter ar...
WP_011563451  89 ISLQARTLMSLVEDVLSELIRQGFERIAVVNWHFENQNFVYEAACLALERHr---gSSARILVAEHpFAELS-EATMKTL 164 Rubrobacter xyl...
WP_011100059  85 IDLNGATLQALIMDIVDEFVRDGFTKIFLLSAHFENEAFIVEAMDLCSQKYg----DKVQILLTNW-WDPMS-PDVIDKI 158 Clostridium tetani
WP_013168384  86 LSLDAGVLIGLVRNIVNELVRHGVRRIVLFDGHMENQWFLVEAADLALRDQamlgrTDVRIVKLGY-WEFIT-KATEKVL 163 Starkeya novella
WP_011067911  85 IDMNGVTVINQMHDVLSELIADGFTKIVVMNAHFENEAFIVEAIDLVTRETg----GVATIVETNW-WDPVP-QSVIDKV 158 Bifidobacterium...
ZP_04668836  162 FPD-GFPGWAREHAACMEVSIMLYRHPELVHFDRAVNDNSEEYPFYDVLPPDPRF-FTKSGTLWHAREATIEKGKLIWEE 239 Clostridiales b...
WP_013946433 165 FPD-GFPGYDLEHAAVMETSLMLHHHPHLVDLSALPDDKPASFPPYDIYPTRTGL-VPCSGVLSPAHGCSAEKGKLLAND 242 Hyphomicrobium
WP_012315116 166 YPE-GFLGWDIEHGGVFETSLMLALHPEKVDLSRAVDHPPAKFPPYDVFPIIPER-TPACGTLSSPKGASREKGELTLRV 243 Pseudomonas putida
WP_012695975 166 YPE-GFTGWDLEHGGVMETSLMLHLFPEYVDMERVDHGDPAVLPNYDVFPIKPEL-TPPSGCLSSAAKSTPEKGKILLDT 243 Laribacter hong...
WP_013167045 165 FPE-GFPGIDLEHASLLETSLMLVLRPELVEMDKAPTDGPAKFPPYDRFPVPDDFgLPPSGVLAVATGSTAEKGEWLMAD 243 Starkeya novella
WP_011913141 161 FPE-GFPGFALEHAAVIETSLMLHFHPQLVALEKIPDDAPADFPPYDMYPTRTEW-VPPSGVLSSARSSSAAKGQRLAHD 238 Pseudomonas stu...
WP_013350048 164 FPD-GFLGWDIEHGGILETSLMLLLHPQLVDMDRVIDHPPAKLTAYDIFPEDPAR-TPDSGCLSSAKGATAERGQLLFET 241 Arthrobacter ar...
WP_011563451 165 FPE-GFPGWDYEHASIMETSLMLHLRPELVLFDRAVDDASKRHPWYDVLPVPEDF-VPASGTLWKATQASEEKGRITWEE 242 Rubrobacter xyl...
WP_011100059 159 FTEvPFPGWALEHAAVTETSLMMYFAPELVREDQILDTENASPATYYRYPIEKDI-VPETGILASAKSSSAEKGKIIVDD 237 Clostridium tetani
WP_013168384 164 FPD-GFPSWELEHAAVMETSVMLHIRPDLVREELIPDDPAADFPPYDIYPFDTRP-IPPTGVLSSAKAASAAKGEAVLAQ 241 Starkeya novella
WP_011067911 159 FDGlVFPGWAMEHAAVTETSLMLHYAPELVHMDRMVEEAGATAKSYVRYPVRQGD-VPAHGGLANPAGSSAERGRLIAEA 237 Bifidobacterium...
ZP_04668836  240 IIKQAGAAINKEF 252 Clostridiales bacterium 1_7_47FAA
WP_013946433 243 YAEGVAAAIRKEF 255 Hyphomicrobium
WP_012315116 244 CVEGISSAVREAF 256 Pseudomonas putida
WP_012695975 244 CTAGIVSAIKREF 256 Laribacter hongkongensis
WP_013167045 244 YVTRISAAMRKEF 256 Starkeya novella
WP_011913141 239 IVEGIAAAVCKEF 251 Pseudomonas stutzeri
WP_013350048 242 VTDQVAQALKGEL 254 Arthrobacter arilaitensis
WP_011563451 243 IVAQFREAVVTEL 255 Rubrobacter xylanophilus
WP_011100059 238 VIPNILKIIDKAF 250 Clostridium tetani
WP_013168384 242 VVPDIADALIKAF 254 Starkeya novella
WP_011067911 238 CVGAVAEICAEEF 250 Bifidobacterium longum
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