Conserved Protein Domain Family
cobN

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PRK05989: cobN 
cobaltochelatase subunit CobN; Reviewed
Statistics
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PSSM-Id: 235663
Aligned: 150 rows
Threshold Bit Score: 1057.19
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
241205086    1 MHLLLAQQGTISD------------------------------------------------------------------- 13  
30248761       --------------------------------------------------------------------------------     
294495832  114 RTYSTGMGNEYNKssnvvlltressnfvlsttsdengnfvlddipfgeyelyaanysesrgewkwykgkidvevngsdlt 193 
161621700      --------------------------------------------------------------------------------     
150403433  100 EAILRMLNRTTISg------------------------------------------------------------------ 113 
159905143  123 TLVLTDKDGEFISnttsdesgnfvfddvqngnytlsgvvwsskgywlanvqevtiengtplenltvkvthdetidseail 202 
73671159   109 SQALLDLPVSEAGlsgsaii------------------------------------------------------------ 128 
21227704    81 SQAILDLKGSGVPleg---------------------------------------------------------------- 96  
161484941   47 SGLTLSKSGDIKA------------------------------------------------------------------- 59  
119898921      --------------------------------------------------------------------------------     
241205086   14 -----------------------------------------GEEAIDLGQTPGDI------------------------- 27  
30248761       --------------------------------------------------------------------------------     
294495832  194 nqsleissssmidenwinsyidgynisgrtystgmgneynkSSNVVLLTRESSNF------------------------- 248 
161621700    1 -----------------------------------------MGGMWLTNVQEIEIengipvgnlsmamrs---------- 29  
150403433  114 ----------------------------------------aTVSKTGSAKVGTTLvltdengdfvtnttsdatgnfsign 153 
159905143  203 rllnrttisgatstamgskagvtlvltdkdgefisnttsdeSGNFVFDDVQNGNYtlsgvvwsskgywlanvqevtieng 282 
73671159   129 ----------------------------------sgltrqkQMNADPIPLGSTNV------------------------- 149 
21227704    97 --------------------------------------assIRGLTRQKQMGGDP------------------------- 113 
161484941   60 -----------------------------------------GTDLVLLKKTSGSSnqdsdssns---------------- 82  
119898921    1 -----------------------------------------MTRLARLWRAALAC------------------------- 14  
241205086      --------------------------------------------------------------------------------     
30248761       --------------------------------------------------------------------------------     
294495832      --------------------------------------------------------------------------------     
161621700      --------------------------------------------------------------------------------     
150403433  154 iqngnytlsgviwstamggmwltdveeieiengspvgnlsmamrsnssndaeailrmlnrttisgatvsktgsakvgttl 233 
159905143  283 tplenltvkvthdetidseailrllnrttisgatstamgskagvtlvltdkdgefisnttsdesgnfvfddvqngnytls 362 
73671159       --------------------------------------------------------------------------------     
21227704       --------------------------------------------------------------------------------     
161484941      --------------------------------------------------------------------------------     
119898921      --------------------------------------------------------------------------------     
241205086      --------------------------------------------------------------------------------     
30248761       --------------------------------------------------------------------------------     
294495832      --------------------------------------------------------------------------------     
161621700      --------------------------------------------------------------------------------     
150403433  234 vltdengdfv---------------------------------------------------------------------- 243 
159905143  363 gvvwsskgywlanvqevtiengtplenltvkvthdetidseailrllnrttisgatstamgskagvtlvltkkiivdtad 442 
73671159       --------------------------------------------------------------------------------     
21227704       --------------------------------------------------------------------------------     
161484941      --------------------------------------------------------------------------------     
119898921      --------------------------------------------------------------------------------     
241205086      --------------------------------------------------------------------------------     
30248761       --------------------------------------------------------------------------------     
294495832      --------------------------------------------------------------------------------     
161621700      --------------------------------------------------------------------------------     
150403433  244 --------------------------tnttsdatgnfsigniqngnytlsgviwstamggmwltdveeieiengspvgnl 297 
159905143  443 eetefvaetwykfisnttsdesgnfvfddvqngnytlsgvvwsskgywlanvqevtiengtplenltvkvthdetidsea 522 
73671159       --------------------------------------------------------------------------------     
21227704       --------------------------------------------------------------------------------     
161484941      --------------------------------------------------------------------------------     
119898921      --------------------------------------------------------------------------------     
241205086   28 -------------------------------------------------------------LFLSAAD------------ 34  
30248761     1 -------------myqsdggnrftffvhdnrymkrifllitlillapaafahkvallstqfVLEHKFR------------ 55  
294495832  249 -------------------------------------------------------------VLSTTSDengnfvlddipf 267 
161621700   30 ----------------------------------------------nssndaeailrmlnrTCISGAT------------ 51  
150403433  298 smamrsnssndaeailrmlnrttisgatvsktgsakvgttlvltkkmvsyvpgevsklnvaIVTGYSN------------ 365 
159905143  523 ilrllnrttisgatstamgskagvtlvltdkdgefisnttsdesgnfvfddvqngnytlsgVVWSSKG------------ 590 
73671159   150 -------------------------------------------------------------LLLKEAG------------ 156 
21227704   114 -------------------------------------------------------------ISLGFTE------------ 120 
161484941   83 ----------------------------------------------------gstshlnvaIITGYSN------------ 98  
119898921   15 -------------------------------------------------------------ALLCLCG------------ 21  
241205086   35 ------------------------------------------------------------S----------ELAAIATA- 43  
30248761    56 ------------------------------------------------------------L----------MQAASEGSg 65  
294495832  268 geyelyaanysesrgewkwykgkidvevngsdltnqsleissssmidenwinsyidgyniSgrtystgmgnEYNKSSNVv 347 
161621700   52 ------------------------------------------------------------VsktgdpkvgtKLVLTKKMv 71  
150403433  366 ------------------------------------------------------------Y----------EKQLSTSTn 375 
159905143  591 ------------------------------------------------------------Y----------WLANVQDVt 600 
73671159   157 ------------------------------------------------------------TetqdnssetqSNSSETQDn 176 
21227704   121 -----------------------------------------------------------------------VLLLREQVk 129 
161484941   99 ------------------------------------------------------------Y----------DLKLNALA- 107 
119898921   22 ---------------------------------------------------------------------------LAQAr 26  
241205086   44 ----HRERRAGPSLRL-------------ASLLS-LKHP----MSVDTY------VERTV-RHA-------------KLI 81  
30248761    66 ----IDLHWVQADREG-------------E-------EG----VRKALA----------------------------EAR 89  
294495832  348 llksLATSSSYPLVNVsiitgyssyepqlESLVGrINNDstlnLSVSYHlpstidDETDL-SNV-------------DVI 413 
161621700   72 ----SYIPGEVSKLNVaivtgysnyekqlSTSTDrINTDsd-lNIVASYyttsnlSADIDlSQM-------------DII 133 
150403433  376 ----RINSNSDLNIVA-------------SYYTT-LTLS----EDIDLS----------------------------QMD 405 
159905143  601 ----IENGTPVENLTVkvthdetidseaiLRLLNrTTIS----GATSTAmgskagVTLVLtDKDgefisnttsdesgNFV 672 
73671159   177 ssqvQSNSSSSQHLNIaivtgyrshelplKNLAEeVNSNnslnLTLSCFmadyvmENDVDlSAM-------------DII 243 
21227704   130 etpvDSSPGQHLDIAIvtgyrs--helplKNLMEeINGNsslnLSLSCFmadyvmENDVDlSGM-------------DII 194 
161484941  108 -----------------------------ERINGnSSLN----MSVSYYlpatsgEDVDL-SDM-------------DII 140 
119898921   27 ptllWINADITPAARV-------------ALVAR-EAEA----ADFNFRkleyrlQGGPLaAAQ-------------QAE 75  
241205086   82 IVRALGG-----------ASYFHYALEALHAA--AARAGALIAVLP---GDARPDA--------GLVPFSNVD------- 130 
30248761    90 LVIIDAP-----------RAEDQAQIEHIAGK--LLRETAVPVVTFqtfGGQ--------------ISPIRLA------- 135 
294495832  414 YAKMFTD--------------SASKIENEVDS--AISNGTIVITDNaalTENIPAE--------FLDDRDEII------- 462 
161621700  134 YIVMVTQ-----------------SAEPIENTiqDAIDNGAVVIGS---NTYLPESn------ySIPEEHADI------- 180 
150403433  406 IIYIVML-----------TQS-AETVENTVQS--AIDNGAVVIGSNtylPES--NY--------SIPEEHTDV------- 454 
159905143  673 FDDVQNGnytlsgvvwssKGYWLANVQEV-----TIENGTPLENLT---VKVTHDEtidseailRLLNRTTISgatstam 744 
73671159   244 YINMLSPs---------tAQKLTPTVDSAIAN--------GCVVID---DDTLLNE--------SIPLPEDQI------- 288 
21227704   195 YINMLSPs---------tARKLTPTVDSAISN--------GCVVID---DDTLLNE--------SIPLPADLI------- 239 
161484941  141 YINMFTD--------------SASKLENTVNE--AIANGAVVIGYNtylPESIDNS--------SLPSSFSDE------- 189 
119898921   76 LEQALAGa----------QRVWVDAPHATAEArlRTVLAEPLGRHAarlGEAG-----------VLWITAGEP------- 127 
241205086      --------------------------------------------------------------------------------     
30248761       --------------------------------------------------------------------------------     
294495832      --------------------------------------------------------------------------------     
161621700      --------------------------------------------------------------------------------     
150403433      --------------------------------------------------------------------------------     
159905143  745 gskagvtlvltkkmvsyvpgevsklntaiitgysnyekqlsistnrinsnsnlnivasyyttsdlsgdidlsqmdiiyiv 824 
73671159       --------------------------------------------------------------------------------     
21227704       --------------------------------------------------------------------------------     
161484941      --------------------------------------------------------------------------------     
119898921      --------------------------------------------------------------------------------     
241205086  131 --------------------------------------------LDDLNALWAYLIEGG--DANARAFLDYAE--AMLSG 162 
30248761   136 --------------------------------------------PEIAERLYGYYVAGQ--KVNRERLFHYLRiwMQGGD 169 
294495832  463 ------------------------------------------------EILEAYWKYGAteESNFDNMIYYLAk-TFVDR 493 
161621700  181 --------------------------------------------ESFKKYLSEYWSGGAsdDENFDNLIFYLAr-EYYNR 215 
150403433  455 --------------------------------------------EAFKKYLSEYWSGGAsdDENFDNLIFYLAseYYNRT 490 
159905143  825 mvtqsaetfedevqkaidngavvigsntylpesnysipeehadvAEFKKYLSEYWSGGAsdDENFDNLIFYLAr-EYYNR 903 
73671159   289 --------------------------------------------ESYREKLNDYWSNGAydQNNLKNLIFCIAsdCCGRS 324 
21227704   240 --------------------------------------------ESYREKLNNYWLNGAydQSNLKNLLFCIAsdCCGRT 275 
161484941  190 --------------------------------------------GELKAYLQDYWVYGAtnDANFDNLIFYLAq-VFYAR 224 
119898921  128 --------------------------------------------AAGDTSLRAYLQAGG--PANTRNAFALARaqLAGAS 161 
241205086  163 AEKPAPAVPLMKAGIWW-------PGRGLIGVEEWRRIVASLQGaplgvappsvlpdisptrgeirdersrsissaegtv 235 
30248761   170 LSEVPPPADLPDGGIYH-------PGHA----DSIFPTLP--EYlnwwekqm---------------------------- 208 
294495832  494 NDLDVKAPDGSPKAIYHpnm--teKSNFTSNSTEYFDWYRNREDghaf-------------------------------- 539 
161621700  216 TDLTVKEPTGLQRAIYHpnmtstpIEFFTGDAGEYFAWYSNRTDghsf-------------------------------- 263 
150403433  491 DLTVKEPSGL-QRAIYH-------PNMTTTPTEFFTGDAG--EYfawysnrte--------------------------- 533 
159905143  904 TDLTVKEPTGLQRAIYH-------PNMTSTVTEFFTGDAEEYFTwysnrtdg---------------------------- 948 
73671159   325 DLLYEEPHTLPERAIYHtn----mTGYFTDSLDTYLAWYSNRSDgghvy------------------------------- 369 
21227704   276 DLLYEDPHTLPERAIYHtn----mTGYFTDSLDTYLTWYSNRSDgghvy------------------------------- 320 
161484941  225 DDLQVSAPEGAASAIYHpgm--vnSSYFTANASEYFEWYGSRNEsehsf------------------------------- 271 
119898921  162 TPTLPPPALVPQGGIYHp-----dATALFANAQAFAAWAAASKPa----------------------------------- 201 
241205086  236 ssnvsfvrspsdlpisplvgemsgrteggttnstqqasPIVAISFYRALVQSGETGPIEALIEALVTLGLRPLPVFAYSL 315 
30248761   209 -------------------------------adpalerPVIAMEIPSTYIADGQTRMLDEVVSALEQAGALPLVFYRSTR 257 
294495832  540 ----------------------------------densPTVGLTFYSSYYP-ERMGPFDSLIAELESRNMNVIACYGSSS 584 
161621700  264 ----------------------------------denaPTVGIAFYTSYYP-NEMDPIDKLIAGFESKGVNVIACYGDAD 308 
150403433  534 ------------------------------ghafdedaPTVGIVFYTSYYP-NEMDPIDKLIAGFELRGVNVIACYGDAD 582 
159905143  949 -------------------------------hafdenaPTVGITFYTSYYP-DDMDPINKLIAGFESRGINVIACHGDAD 996 
73671159   370 ----------------------------------dpakPTIAITMYQSYFP-FQIEPIDALISKLEAKDYNVIATYGSDD 414 
21227704   321 ----------------------------------dpakPTVAITMYQSYFP-FQIEPIDALISELEAREYNVIATYGSDN 365 
161484941  272 ----------------------------------denaPTVGILFYLSYYP-ADMQPIDALIEEFESRGVNVIACYGSSK 316 
119898921  202 -------------------------------------rPAVALLLHRYHFVQGNTAWLDDWLRRFERQGITAYAVFSSHL 244 
241205086  316 -----------------------------KDPV------STGILESVF---STLK------------------------P 333 
30248761   258 isrgstvqvsgsnesnrrpgatgnrgfgeRGSAgagadnSRENPVDIVqprGSADfpnpaerrnitideplityqgkiiP 337 
294495832  585 -----------------------------------------DYVDPFFnhtPETK------------------------V 599 
161621700  309 -----------------------------------------NQLDGFFnynNNTK------------------------V 323 
150403433  583 -----------------------------------------NQLDYYLnynNETK------------------------V 597 
159905143  997 -----------------------------------------NQLDDFLnynNETK------------------------V 1011
73671159   415 -----------------------------------------LASGDFFkqgDEVL------------------------V 429 
21227704   366 -----------------------------------------LSSGDFFkqgDEVL------------------------V 380 
161484941  317 -----------------------------------------EYVDKFLnynSSTK------------------------A 331 
119898921  245 ---------------------------------------------------SDKP------------------------L 249 
241205086  334 DVVINTTGFAVSA-PGADRq--aTVL----------EANEAIVLQAILSA-SSREAWAASSQGLSARDLGMNVALPEVDG 399 
30248761   338 QVILVNTFLGSAP--ENRK----AWH----------QALGIPAINVLSYRgGTRTDYLKDSAGIGSYFVPFTLTTAEYIG 401 
294495832  600 DLILSSTYRSQYF----DI-----------------ENLGVPVMNTVTNGyMNLTEWKETSSPL-PNTYMIRLYRPETWG 657 
161621700  324 DAVISFLYRGTYFn---------------------mEELGVPVIDGVLNGyMNTSEWIETSNPL-PVTNMLRIYRPESEG 381 
150403433  598 DAVISFLYRGTYFd---------------------lEELGVPVIDGVLNGyMNTSEWIETSNPL-PVTNMLRIYRPESEG 655 
159905143 1012 DAVISFMYRGNYF----DL-----------------AELGVPVIDGVLNGyMNTSEWVETSNPL-PVANMLRIYRPESEG 1069
73671159   430 DAIISFTYFGNKF----DA-----------------EELGVPVINGIVDNyMNRTDYEASSRPL-PADKMMKLDLQELWG 487 
21227704   381 DAIISFTYFGNKF----DA-----------------EGLDVPVINGIVNNyMNRTGYEASSRPL-PADKMMKLDLQELWG 438 
161484941  332 DLIVSTTYRSQYF----DV-----------------EELGVPVINCVLNGyMNLSEWQNVSDPL-TNTYMIRLYRPETWG 389 
119898921  250 ADLLEVPGADGARtLHPRLivthTLLpqgatlqpvfERWGVPVLATQPYRqGDTAAWEASPTGLGQGDVAYYFAQPEAAG 329 
241205086  400 RVLARAISFKTAarydaaVETNIVASEPDTGRVRYTAELAANWARLRKTSAHDRRIALVMANYPN--RDGRLGNGVGLDT 477 
30248761   402 LQDPVVLTTNE--------GG---EFVPLPEQLDLLVGKAINLARLSLRANADKRVALLFWNHPPgeKNQ---GASNLNV 467 
294495832  658 WIDPIMIASTEF------DSQGNKIYEPVDTQVEWLVDRAEAQTNLSAKDHSDKKVVVLYYNHGA--GKNNIGASY-LEV 728 
161621700  382 LIDPIMIGAEETvl---eDNDTISKYMGHDTQIEWLINRTIAQCNLGIDPENEKKVAIIYYNHEG--GKNNIGASY-LEV 455 
150403433  656 LIDPIMIAATEEvled---nttISKYIGHDTQIEWLINRTIAQCNLGIESESEKKVAIIYYNHEG--GKNNIGASY-LEV 729 
159905143 1070 LIDPIMIGATESlf---eDNMTISKYIGHDTQIEWLINRTIAQCNLGIEPESEKKVAIIYYNHEG--GKNNIGASY-LEV 1143
73671159   488 AIDPIIMAATEVd-----PETETETSVSIDYQVDWLVDRVESWVNLSEIPESDKKVAIIYYNHGG--GKDNIGASY-LDV 559 
21227704   439 AIDPVIMAATEId-----PETGTETSVSIDYQVDWLIDRVESWVNLGEIPDSDKKVAIIYYNHGG--GKDNIGASY-LDV 510 
161484941  390 WIDPIMIASNELd-----NETNTEVYVPVEAQVEWLVDRAVSQTDLSGKSESEKKVAILYYSHGC--GNDSIGASY-LEV 461 
119898921  330 TIDPVLVVAHPP---------GGAEPQLIARQADAVVAKAARLIRLQTTPAADKRLVAMVYNYPP--GGGNFGASF-LNV 397 
241205086  478 PAGTTEVLKAMRAVGYPV----AEIP--AD---GDALIR---HLMEGPTNS----GSD----GKIIRETLSLSLYNSFLE 537 
30248761   468 PRSLEYLVEHLRSEGYAFeavtE-----QQ---MIDTVGq--MLR-----PayraGGIpelmRTPHWDFLPLARYRAWYA 532 
294495832  729 VPSIGNLLGAMANESYDVq--sSSIP--NK----TELVDl--FVKQGTNIGtwapGELedlvETNKVELIPEHTYRKWFD 798 
161621700  456 APSIVNLLNAMDSDGYNIn--eSIIP--NK----TELVDl--ILLQGRNIGswapGELeslvETGEVELIPEETYISWFN 525 
150403433  730 APSIVNLLNSMELDGYDI----N-ESmiPN---KTELVDl--MLLQGRNIGswapGELeslvETGEVELIPEETYISWFN 799 
159905143 1144 APSIVNLLNAMDSDGYAIne---sII--PN---KTELVDl--MLLQGRNIGswapGELesivETGEVELIPEETYISWFN 1213
73671159   560 IPSLSNLLDAMSKDGYAL----NE----NQtlnETDLLNl--MLTQGINIGtwapGELqkmvDTGKVVLLPESTYEKWFS 629 
21227704   511 VPSLSSLLDAMAAGGYAI----NE----NQslnETELLNl--MLTQGINIGtwapGELekmvATGKVVLVPESTYEVWFS 580 
161484941  462 IPSINNLLEGMADEGYDId--kDSIP--NE----SELTNl--MLKQGTNIGtwapGELerlvESGEVELIPESTYLEWFS 531 
119898921  398 PRSLENVSGELQRAGYAV----TPLP-------EADWIRrlqPLIGAYYPNadlrALL----ASDQAAALPLADYQAWFD 462 
241205086  538 SLPDKIQDEVRARWGNPQDDPYFR-----EGVFALPFARFG-EVLVGIQPARG---YNIDPKESYHSPDLVPPHGYLAFY 608 
30248761   533 TLPESVRNDIEARWGN-PEESVWLahkdsvnGFVIPRMQLG-NLVVMPQPSRGemaGMEEEKKLFHDTRQPPGHAYLASY 610 
294495832  799 TLPEERRKEVTDRWGEAPGEIMVYeddsgDRFVVIPKIEISdNVILAPQPTRG---WFDDLDALYHDADLPPHHQYIAFY 875 
161621700  526 ELPEERRNEVVETWGEAPGELMVYeysngSKYIVIPKISMSdNVIVAPQPSRG---WMDSYDTLYHDTELPPNHQYIAFY 602 
150403433  800 ELPEKRRNEVVETWGEAPGDLMVYednngskYIVIPKISMSdNVIVLPQPSRG---WMDSYDTLYHDTELPPNHQYIAFY 876 
159905143 1214 ELPEERRSEVVETWGEAPGDLMVYedtngskYIVIPKISMSdNVIVAPQPSRG---LMDSYDTLYHDTELPPNHQYIAFY 1290
73671159   630 ELPEERQQEVIDQWGPAPGKIMVWen-etGKYLVIPRIEVGkNVILAPQPSRG---WLDDNEALYHDKDLPPHHQYIAFY 705 
21227704   581 ELPEEKQQEVIEQWGPAPGEIMVWen-esGRYLVIPRIEVGdNVLLAPQPSRG---WLDDSEALYHDSELPPHHQYIAFY 656 
161484941  532 ALPEERQQEVLETWGPAPGEIMVYeddsgDKFLVIPKVEVSdNVILAPQPTRG---WLSDNELLYHDGDLPPHHQYLAFY 608 
119898921  463 RLPQDLRRMISARWGEPAESRYLVew-qgRRVFVIPRVRAG-ALDVLPQPPREe-tLRQGQDPFMHKSKTPISHHYLATY 539 
241205086  609 AFLR-----REFGAHAIIHMGKHGNLEWLPGKALALSETCYPEAILGPLPHLYPFIVNDPGEGTQAKRRTAAVIIDHLTP 683 
30248761   611 LWIR-----EQFSADAIVHFGTHGTQEWTPGKERGLWAYDYPNILVGNLPVIYPYIVDNIGEAIHVKRRGRGVIISHQTP 685 
294495832  876 LWLQ-----NDFDADVMVNMGRHGTVEWLPGKEFGLFSEEWPALMVGDIPVVYPYVMDGMGEGMQAKRRGSAVVIDHLIP 950 
161621700  603 LWLQ-----KEFDADVMVNMGRHGTVEWLPGKEFCLLSDEWPALMVGDIPVVYPYVMDGTGEGMQAKRRGSAIIIDHLIP 677 
150403433  877 LWLQ-----KEFDADVMVNMGRHGTVEWLPGKEFCLLSDEWPALMVGDIPVVYPYVMDGTGEGMQAKRRGNAIIIDHLIP 951 
159905143 1291 LWLQ-----KEFDADVMVNMGRHGTVEWLPGKEFCLLSDEWPAIMTGDIPVVYPYVMDGTGEGMQAKRRGNAIIIDHLIP 1365
73671159   706 LWLQhseeeGGFDSDALVHFGRHGTQEWLPGKEFGLSRYDWPSLMIGDKPVIYPYVMDGLGEGNEAKRRGGAVIVDHLVP 785 
21227704   657 LWLQhseeeGGFGSDALVHFGRHGTQEWLPGKEFGLSRYDWPSLMIGDLPVIYPYVMDGLGEGNEAKRRGGAVIVDHLVP 736 
161484941  609 LWLQ-----NEYGADAIVNMGRHGTVEWLPGKEFCLFSDEWPAIISGDIPVIYPYIMDGMGEGMQAKRRGNAVIIDHLVP 683 
119898921  540 LWAQ--------QADALIHFGTHGTQEWAPGKLRGLDVHDQAWLPLGDLPVIYPYIVDNLGEATTAKRRGRALMISHRTP 611 
241205086  684 PLTRAESYGPLKDLEALVDEYYEASGGDPRRIRLLSRQILELVADIGLDRDAGIAKGESEGEA-----LKKLDAYLCDLK 758 
30248761   686 AFSPAGLSDDFVRLNDLIREYQSLDQGL--VRDNNRKLIIEQAVRMNIHQDMQWKVADLERNFdn--fLRDIEDYLEDLG 761 
294495832  951 PVVMSGSYGNYTDLNEKISQYHALDS-DPDTQETRFEEIVNLTYELHLDERINMTYAEAEDEDlrdhfLDELDDVLRELR 1029
161621700  678 PVVSAGLYGNYSLLNSEIASYQTSVTESESLKQAQFEEIVNLTFELGLENRVNMSLSENNGTIde--fLDELDDVLRDLR 755 
150403433  952 PVISAGLYGNYSLLNSEIASYSTSVTESESLKQAQFEEILNLTIELGLESRVNMSLAENESTVde--fLDELDEVLRELR 1029
159905143 1366 PVISAGLYGNYSLLNSEIASYQTSVTESESLKQAQLEEIVNLTVQLDLEDRVNMSLVQNESTIdd--fLDELDDVLRDLR 1443
73671159   786 PILSAGSYGNYSNLSEAIQNYEQA-EADASLKAAHRSEVLNLTQSLSLDKELNMTEAENNETYfnttfLEGLEDLLDEYK 864 
21227704   737 PIVSAGSYGDYANLSEAIHNYGQA-EADASLKAAHRSEVLNLTLSLSLDEEFNMTEAENNETYfnavfLEGLEELLDEYK 815 
161484941  684 PVVLSESYGNYTELSSKISQYQTL-PSESELKELRMQEIVNLTMELSLDEFVNVSLSESEDTEee--fLDELDDILEELK 760 
119898921  612 GFSPAGFNKRMGHMHELMHEWETADVG--PTRSALEQQLIAVFVEQQLHRDLGWTAERIAADFag--fLELLHPYLDRLA 687 
241205086  759 EMQIRDGLHVFGVSPEGRLLTDLTVALArvprglgeggDASLHRAIAADAGLGggmrgippsvlpdisptrgeigderpr 838 
30248761   762 TAQQPLGLHTLGRDAEQAHQISNVMQML---------------------------------------------------- 789 
294495832 1030 TTSMPYGLHILGKAPKGEQLSEMVCSML---------------------------------------------------- 1057
161621700  756 TLSMPYGLHVLGEAPDDDELVGMVNSML---------------------------------------------------- 783 
150403433 1030 TLSMPYGLHVLGEAPAGDELVGMVNSML---------------------------------------------------- 1057
159905143 1444 TLSMPYGLHVLGEAPEGEELVGMVNSML---------------------------------------------------- 1471
73671159   865 SQSMPYGLHILGTSPKGEQLVGMVNSML---------------------------------------------------- 892 
21227704   816 GQSMPYGLHILGTSPKGEQLVGMVNSML---------------------------------------------------- 843 
161484941  761 TTSMPYGLHILGTSPEGENLTQMVYSML---------------------------------------------------- 788 
119898921  688 QSSQPKGLAVFGRVPDAADRHQTILQML----------REPLIEALGEDIDEAflid----------------------- 734 
241205086  839 liscvagaassngsfsgspsdlpisplvgemsgrteggasifdplNTEMAAPWT---GPRPAILADILDAPWRTNGDTVE 915 
30248761   790 ---------------------------------------------------------GQPLYDLLGIEDARTLLREDYRK 812 
294495832 1058 ---------------------------------------------GKDFKDEVAqynTSEKAPVLLLDLVLNQNTSSTDA 1092
161621700  784 ---------------------------------------------GSSYSEKVAaynSSDSAANDLLTKVLLENITIDDA 818 
150403433 1058 ---------------------------------------------GSSYSEKVAiynSSDSAATDLLTKVLLENISIDDA 1092
159905143 1472 ---------------------------------------------GSSYYEKVAlynNSDSAANDLLTKVLLENVTIDNA 1506
73671159   893 ---------------------------------------------GTDFADSVNefnKTEGAQLYLLDLVLNQGVNSTNA 927 
21227704   844 ---------------------------------------------GTDFADSVSefnETEGSQLYLLDLVLNQGVNSTEA 878 
161484941  789 ---------------------------------------------GDDFSEEVAeynSSENASLDLLDLVLLQNVSIEDA 823 
119898921  735 -----------------------------------------hegvARSRPSRWLevaLQDAEAASRLDLRPPEPEGPVPN 773 
241205086  916 RIELLAAKFVSgemecp----tlwsqtRCVLSEIETRLKPSILACgPAEIAGLLAGLDGRFVAPGPSGAPTRgRPDVLPT 991 
30248761   813 IQQSEPYRFVEtyvfsdqplndindpgLRAMAERGRTFRMNLH-A-APEIDSIVKGLSSRWIDPSYGGDPIR-NPDALPT 889 
294495832 1093 QLQILGEGNNSd--------------tMDNYLSKATEYSDKLSLT-EDELQQLLKAMDGKYVEPNLGGDPIQ-RSDALPS 1156
161621700  819 QMQVLGTTSED----------------IETDLQLAITYSELLLEA-DDEIEQVLKAMNGEYIEPGLGGDPIL-RPETLPS 880 
150403433 1093 QMQVLGNTSED----------------IECDLQLAINYSALLLEA-DNEIEQVLKAMNGEYIEPGLGGDPIL-RPETLPS 1154
159905143 1507 QMQVLGTTSED----------------IENDLQLAINYSALLLEA-DNEIEQVLKAMNGEYIEPGLGGDPIL-RPETLPS 1568
73671159   928 QKQVLGKSNET----------------VSTLLSNAEEYAANLALG-EEEIDQVLNALDGKFIPGNLGGDPVR-NPETLPS 989 
21227704   879 QVQVLGTGNET----------------VSTFLVSAEEYAANLALG-EEEIQQVLNALDGRFIPGNQGGDPVR-NPEALPS 940 
161484941  824 QIQVLGSSSEE----------------VTGYLTTAQEYAEKLGES-KNEIQQVLKALDGEYIEPNIGGDPIL-RPDALPS 885 
119898921  774 RAARKAIDSAA----------------LRELALRAQEMERRLAIE--GEIPGLLAALDGRFVPAAYGGDPLR-NPDSVPT 834 
241205086  992 GRNFYSVDSRAVPTPAAYELGKKSAELLVRRYVQDH--GEWPVSFGLTAWGTSNMRTGGDDIAQALALIGVKPLWDMSSR 1069
30248761   890 GRNMYGFDPGRVPTRAAYEAGGQAVEQLIASYKLTH--DKFPEKLAFSMWSTETMRHLGMLEAQIFYAMGVRPVWDEGG- 966 
294495832 1157 GRNFYAFDEQLIPTKQSWELGKKMANETMDAYQEKHgdDAYPSKAAFILWAGESTRHEGVMEAEILYLLGVRPVWGSGD- 1235
161621700  881 GSNFYAFDEQLVPTKQAWEEGKALVDEWLSQYYDEN--GEYPTKVAYILWAGESTRHQGIMEAQILYMLGVKPVWNENNG 958 
150403433 1155 GSNFYAFDEQLIPTKQAWEEGKALVDEWLSEYYEEN--GEYPTKVAYILWAGESTRHQGIMEAQILYMLGVQPVWNENNG 1232
159905143 1569 GSNFYSFDEQLVPTKQAWEEGKALVDEWLSEYYNEN--GEYPTKVAYILWAGESTRHQGIMEAQILYMLGVKPVWDTSSG 1646
73671159   990 GRNFYAFDQRIVPTEAAWTLGQEMADQMLEAYVTEH--GTYPKKVAYVLWAGETTRHEGVMEAEILYLLGVKPVW--NSG 1065
21227704   941 GRNFYAFDQRIVPTEAAWTLGQEMADQMLEAYLAEH--GNYPRKVAYVLWAGETTRHEGVMEAEILSLLGVKPVW--NSG 1016
161484941  886 GRNFYAFDEQLSPTKQAWELGKEMANQTIETYQANHe-GQYPKKIGLILWAGESTRNEGVTEAEIFYLLGVKPVWDDDGD 964 
119898921  835 GRNLTGLDPSRLPTRQAYDVARKL---FAAWYAEQAaaGRAPQRFALSLWAGETLRHQGVMEAQALVALGVEPVWD-ANG 910 
241205086 1070 RVTGYEIIPPAMLGRPRVDVTLRISGFFRDAFPEQIALFDKAIRAVGAL---------------------EEDEADNPIA 1128
30248761   967 RVTGMEVIPLSELGRPRIDTVISLTGLYRDQFPNVMERFNQAITLLAEQ---------------------DEPDSDNPIR 1025
294495832 1236 KVEDVELIPSSELDRPRIDVLVQISGLYRDSFPHKVELIDKAVYLAYNApdngydgtkdeerpaaeyisyDSADNTNYVR 1315
161621700  959 KVTDVEIINSSELNRPRIDVVVQISGLYRDSFPMKVQLIDKAVRLAYEE---------------------DEP--DNYVR 1015
150403433 1233 KVTDVEIINSSELNRPRIDVVVQISGLYRDSFPMKVQLIDKAVRLAYEE---------------------DEP--NNYVR 1289
159905143 1647 KVTDVEIINSSELNRPRIDVVVQISGLYRDSFPMKVQLIDKAVRLAYAE---------------------DEPE--NYVR 1703
73671159  1066 RVVDVEAIPMETLGRPRIDVVMQISGLYRDMYPDKVRLLDKAVKLAYAQ---------------------EDS--PNYVR 1122
21227704  1017 RVVDVEAIPMETLGRPRIDVVIQISGLYRDMYPDKVRLLDKAVKLAYAQ---------------------EDS--PNYIR 1073
161484941  965 EVIDVELINSSELGRPRIDVLVQISGLYRDTFPHKVELIDKAVYLAYNDpdnqygkdee--rptpeyisyDPEENTNYVR 1042
119898921  911 RPNGVRVLPQAELGRPRVDVLLSITGSYRDQFPALMNLIDQGVAAAATA------------------------EPDNAVA 966 
241205086 1129 VRMRGEAARL-AAAGLDEVSAKRRAGYRVFGSKPGAYGAGLQALI-DEKGWER-RADLAEAYLVWGSYAYGAG------- 1198
30248761  1026 ANTRRIRAQL-KKLGVTPETAREFALTRIFGNESGDYSTRLTQATlASDKWDEkDGKLENLYLSRMSWAYGPNpahwsqk 1104
294495832 1316 ENTNNIYDGL-NATLQNETASMNIALLRIFGPADGSYGTGMSNAVsASDTWEN-NTELADLYMDRMSNAYGEY------- 1386
161621700 1016 INTDELKDVL-NEHLQNESLSLDIAQFRLFGPADGNYGTGMANAVsSSETWND-TDALAELYISRMSYIYGQN------- 1086
150403433 1290 INTNELQKAL-NETIQNETLSLDIAQFRIFGPADGNYGTGMANAVsSSETWND-TDALAELYISRMSYIYGQN------- 1360
159905143 1704 INSNELQDVL-NETIKNESLSLDIAQFRIFGPADGNYGTGMANAVsSSETWND-TDALAELYINRMSYIYGQN------- 1774
73671159  1123 ENADALKSSLtSEGSLNDSEALDLSLLRIFGSSDGAYGTGLPNAIsSSDTWES-NDALAELYINKMCNAYGED------- 1194
21227704  1074 ENADALKTSLmSEGSLNESEALDLSLLRIFGSEDGAYGTGLPNAVsASDTWES-NDALADLYINRMCNAYGEN------- 1145
161484941 1043 ENTNDLFLVL-NESLQNETASMTVALLRVFGPEDGTYGTGLSNVVsASNSSTS---EIAELYIDRMSYVYGED------- 1111
119898921  967 RNTRTVQAEL-RKAGIGEADAAALAQARVFGNAAGDYGTGVADAV-QSNGLKAgDERLGELFLQRMSQPY---------- 1034
241205086 1199 -EEGKA--------ERG----------------LFEERLRSVQAVIQNQDNREHDLLDSDDYYQFEGGMAAATEQLT-GA 1252
30248761  1105 lTDGKGn-------EIN----------------AYAEHLRGTSAAVFSRSSNLRGLLDTDHPFEYLGGISMAVRHLD-GT 1160
294495832 1387 -VWGES--------MEEiasqwdvaddsidnkdVFNDNLEDVGAIVHSRSSNTYGAMDTDDFFQYFGGLNLVVSEAS-GM 1456
161621700 1087 -IWGQT--------ISEyielqtgqnveinntiIFENNINDVSDIFHSRSSNTYGSLDTNDFFQYVGGLINAITYES-GE 1156
150403433 1361 -IWGQT--------ISEyielqtgqnveidneiIFENNINDVSDIFHSRSSNTYGAIDTNDFYQYVGGLINAITYES-GE 1430
159905143 1775 -IWGQT--------ISEyielqtgqnieinntvLFENNLDDIGDIFHSRSSNTYGSLDTNDFFQYVGGLINAITYES-GE 1844
73671159  1195 -VWGED--------LKD----------------LFKENLEGVEATVHSRSTNLYGTLDNDDFFQYLGGLNLAISSVSgGE 1249
21227704  1146 -VWGEN--------LKD----------------LFKKNLEGVEATVHSRSTNLYGTLDNDDFFQYLGGLNLAVSSVSgGE 1200
161484941 1112 -VWGES--------IADivsqfqvdgsslentdIFKDNLGDVEATVFSRSSSTYGILDNSDAFEYLGGLNLAVSSVS-GE 1181
119898921 1035 -VNGEAmalsrpdaAAQ----------------ALGAHLRHTDAALMSRTSHLYAMVSSDDPFQYLGGLAAAARSAGkRE 1097
241205086 1253 RPSIYHNDHSRPERPVIRSLEEEIGRVVRGRVVNPKWIAGVMRHGYKGAAEIAATVDYLFAFSATT-GAVGEHHFDAVYQ 1331
30248761  1161 SPQLYISNLRDPARARLESAEKFMARELRAVYQHPNWIREMQKEGYSGTLQMLDTINNFWGWQVMDrNITRDDQWEEFHQ 1240
294495832 1457 APETYVMNLQNPDAEKIETLSTYLSREIVTRYLNPTWFEGMQQHGFEGAGKMGNFIENLWGWEALHpDLIADHVWNDVYD 1536
161621700 1157 SPDAHVVNLQNADDQKIESLQTYLENELYSRYYNPTWITGMQESGFEGATEMEKFVENLWGWEALTsDIISDGMWNKVYD 1236
150403433 1431 SPDAYVVNLQNADDQKVVSLQTYIENELYSRYYNPTWITGMQESGFEGATEMEKFVENLWGWEALTsDIITDEMWNKVYD 1510
159905143 1845 APNAYVVNLQIADDQKIETLKNYIENELYARYYNPLWITGMQESGFEGATEMEKFIENLWGWEALTsGLIDDEMWNKAYD 1924
73671159  1250 YPDSYITNMLTNGDEKTETLEKFLTRETYSRYFNSKWIEGMQGSGYAGAREMSDFVENLWGWEATNpDLISDDMWNQVYK 1329
21227704  1201 YPDSFITNMLAGGDEKTETLEEFLKRETYSRYFNPRWIDGMQGNGYAGAREMSDFVENLWGWEATNpDLISDDMWNKVYQ 1280
161484941 1182 YPDSYIMNLQNSGDEEIETLNEYLTREIITRVLNPKSIEGMLGSGFEGVSQLADYVENLWGWEKTNpDLVSDDIWNKVYE 1261
119898921 1098 ALELHVSQLQDGAQAFTETASRSIALEMQSRYLHPGWLKAQREEGWAGTLQVLKAVQYSFGWQNTApDTVRPDHWQSFHD 1177
241205086 1332 AFVADD---GVRDFMIEKNPAAFDEMRERLLEAIDRSLWTPRSNSARFDLAARQQNEVNQ 1388
30248761  1241 SYIADRynlDMRDWFEKSNPAALAQIAERMLEAIRKDYWEASEQTRRELVEVYTDIANRH 1300
294495832 1537 AYFT-G---ENREWIKETNPYEYQSMNARMLETARKNGWDASDEQLKSLVSEFVESIAET 1592
161621700 1237 TYVTDS---ELSAWLNENNPYAYQSMTARMLETARKGCWDASGETLKNLANEFIQSVAEY 1293
150403433 1511 TYVANS---ELSGWLNENNPYAYQSMTARMMETSRKGYWDASGETLEFLANEFIQSVIEY 1567
159905143 1925 TYVADS---ELNGWLNENNPYAYQSMTARMMETARKDYWNADDAVLENLANEFIQSVVEY 1981
73671159  1330 TYVADQ---ELSNWIKKNNPYAYQSMTARMLETARKGNWDASDEVLESLATEYEDSVVED 1386
21227704  1281 TYMADQ---ELSDWVKQNNPYAYQSMTARMLETARKGSWDASDDVLKSLAEEYAESVVED 1337
161484941 1262 TYVADS---ELNAELKATNAYAYQSITARMLETALEGNWDASDEALKNLATEYAESVVEN 1318
119898921 1178 VLVRDRhqlGLPEWLRQ-NPQAYAQALERLIQADRLGYWK-PDAETRKELAGLYRELSRE 1235
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