Conserved Protein Domain Family
CobT2

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COG4547: CobT2 
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]
Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Statistics
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PSSM-Id: 443611
Aligned: 110 rows
Threshold Bit Score: 748.929
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_119679883   1 MAQQDTPLEAFKRATSACVRAISEKRELTVGF-AAD-------APnapasSLLG---ARVRVPLPPRDLNAREVASVRGA 69 
WP_013046776   4 HDPKFDKEAQFLKSNAAALRAVAGVKECQVTY-AGT-------DT-----HVGT---DDVRLPALPPTATAAQKASLRGA 67 
WP_011179906  16 SPNSTLDAEAFKKAISSCIRAIAGTHELEVSF-SHHr-----pSP-----SLNG---NYAHLPELSQHATDKDVSITRGL 81 
WP_007089036   1 -MKNDEALSGFLRGTAATFRALAGRNDLEVGFvKGG-------RA-----GGYG---EHVRLPMPKQALPKDEVADLRGV 64 
WP_015088550   8 NHSNDQAFECFKTSIAACLRAMSGKVNLEVIY-STQ-------LA-----LNSS---SSAYLPLPAKQLNPDTLAYLRGE 71 
WP_077805984   8 NSDDLERNENFRRVTAATLRAVGGRPETEVAF-ANN-------AS-----ARDAqrtAEVRLPYLSRAMPPAEVARIRGA 74 
WP_081563220   1 ---msDPHELFRKATFATQRALSGHQDVPMTP------------------ALASl---------eRAALTPEDKTYIRGA 50 
WP_088921344   1 ----------MHRSLEACARSLADDPALE--------------------------------FPEQ---------PESRGA 29 
WP_088921739   1 ------mpAAFRQSTGACARAIARDRSIDITF-DEN-------AE-----DVEG-----MVLPGIPDDATALERLQTRGR 56 
WP_122122886  14 NFQTAYNPERFKQALIGTIHTLSGYTATNINF-CSNtvnnrqyQS-----KNNK---ENVYLPQPPEIQDAKTLQFIRGQ 84 
WP_119679883  70 ADSAALRLKHHDADVHALRMPTGETARQAYEALEQARVEAIGARDMIGVAQNLGAALEERYR-------RQGFDRISDR- 141
WP_013046776  68 ADGAALWIAHHDPKTHKKHCPNPDGARAIFESAERARVEAIGANDLAGVGANLTAALNQRYE-------TRQIEAPGSA- 139
WP_011179906  82 GDSIALRKAWHNNSIHTRLAPVESKARAVFDALEQTRVEAIGTLAMEGIAQNLDRMLADKYQ-------KTHYRKINTQ- 153
WP_007089036  65 ADGWALKLRHHDVALHARRMPEAAEAQAVYDALETARCEAVGSRYFPGVRKNLREHAEQDCR-------AKNFHRLTAR- 136
WP_015088550  72 ADSIALYLKHHNKEIHARYAPKSQTERKIFDVMEQARTEALGALCMPGVAHNLSVRLNNNFK-------PKEDLDRGKK- 143
WP_077805984  75 ADAAALKIRHHDAQLHAASMPGETIARDVYGAVEQARCEVYGSRHMAGMQANLDRKVAQDCI-------DAGCGKMLNQ- 146
WP_081563220  51 TDAVALRQRHHDPE--KRITIPDAQTQTITDGMEQARCEVYGARHMAGVQANLEDYLGRRLH-------ALNSAKMIVQ- 120
WP_088921344  30 LDAKALHRAYHDVQLQRRYAPENGVAAILFNILETERYEALGANQYAGVQKNLDARRHPQVLgetnhfvSEALTAGAPAa 109
WP_088921739  57 SDAIALYKQYHDARTHARYQPQTDTSQRLHAMAEQTRVELLGANLYEGVGRNLDAALDGRYRlll-dtiRKPVINLGEVg 135
WP_122122886  85 ADALALYLKYHDNDLPSPPDLTSEDAQNSFNALEQVRVEALGSKKMAGVAANLQAVMEHNSH-------IEGHAKMNKA- 156
WP_119679883 142 ----DQAP--------------LSDALRLLAREAITGAEPPPS-ARSA--VELWRPWVQDKLGDSLGSLAGLMDDQDAYA 200
WP_013046776 140 ----DEAG--------------IAEVVRLLLREELTGAPPPQT-LSMV--MDLWRPWVKSRAGDLLDQLEANIDDQSQFA 198
WP_011179906 154 ----SEAP--------------IQDAIALLLREKITKRPPPKE-AGPV--LELWRHSIEQKAAAQLNELAHHIHNQHAFA 212
WP_007089036 137 ----EDAP--------------FADAIGMLAREIFTGEPAPSS-ARPL--IDLWRAHIEENAGTDLNDLRDLIDDQDAFA 195
WP_015088550 144 ----NELS--------------LEDVMYLIAWESITGELPPKY-VQEL--IGLWRLWLHNKVGNSLKQLIINIKNQNAFA 202
WP_077805984 147 ----QDMG--------------APLALSLLAREAMSGTPAPRQ-AGPA--LQAWRDALTPDARSALAEMARHQDDQRAFA 205
WP_081563220 121 ----DDMP--------------MPLALELLTREALSGRKLPESmTGPA--LAAWRQSLTPRAREALARLADVQNDQTLFN 180
WP_088921344 110 gapaAEVPatiepgsgeavllrLQLALRFVCRQAFRQRVTIGSqSDSLpdLNTELALINTHLQPHLSRLVELLGEQALFA 189
WP_088921739 136 ---ePRLG--------------IEHALTLYLREQLSDRPLSPA-ADEV--LSDWREWLKSDVSSKFKPADFNLDDQAGFA 195
WP_122122886 157 ----EQLS--------------PAKALSLLVYETLTGKTVPIA-SRKI--LQLWRNQLTPLGEKALKAMKEALTDQDHYA 215
WP_119679883 201 RSVRRLLTDLDME--VGAEPEMEE-GQED-ESGEDQ--EQGQDPdqdNSGGEQD-SG--NQQQVQ-SD-ETGeTQ---VE 266
WP_013046776 199 EISRRLIGALETDlgDASSNPDDD-ADEGsDEDDSG--DSQSDQ------DGEQsAVgeDQSEGD-DS-QSM-DD---AG 263
WP_011179906 213 QIVRQMLFALKMA--AQLEETSDS-VDNK-KVRNRC--KSENKAe--EDSENEK-QDqsEKQTTT-EQ-E---SD---AQ 275
WP_007089036 196 RGLRRLLDHLSLE--DDIDEAPPE-NDGE-DEDEKEgeTDPDEE---LDSQGGQ-QGqaDESEPDg-------DD---QQ 257
WP_015088550 203 QLVCQIITNLELV--EPDTCKETT-IDKYpTINNSE--------------YYNViNQsnDLTNA--KA-Qt--KD---NN 257
WP_077805984 206 NACSHLLRACALT--ETQQEDEDS-SEQGeDTDDKA--EQDQAT------QNDD-APpeDESQDD-EN-S---GY---QA 265
WP_081563220 181 EASQRFVHVLTLK--ETGEAEEE--PDPSkSRGQSQd-DQTESGe--SSAPDPD-GQeeEDSTAE-DA-QAAlSD----- 245
WP_088921344 190 QLTRQLCVSLANA--SAGDSHAMVsGDTS-SPDDM---VEEDSEvpdED-EDESaSEsdEPESAE-QS-EKS-SDevpDD 259
WP_088921739 196 RALGKLLRSLELE--DGE--PSDN-PDEF-DDEDQA--QDESQTp-qDDSESSEsDStdSQDEADsDAqE---------- 256
WP_122122886 216 QATKQLLQAYRLL--EGEEEKSDN-GKEE-SSQDTA--DQNKDS------NPDYpEEkqEQQES--EL-E--------QQ 272
WP_119679883 267 --ETGAGE-EARD-DAAEM----GEG-AGSee-pGTPGEPYRPD---RWRNEPDPAGYKAFLTAFDEVVDAAELCDSDEL 333
WP_013046776 264 --DSGSSQ-EGEM-GEADG----AEEgM------SDGDSPNSDMtghNANRGTADDSYRTFETKFDEIVSAADLCDPEEL 329
WP_011179906 276 --DKGKTQ-AAQS-NEGDK----AEEeQESaw-qEKPSKPKRLLa--VSDQMEGLADYKIFTRQFDEVLEATDFCSESEL 344
WP_007089036 258 --QDAGTE-EAEA-GEGDId---DQQlEAMsq-eEQPAGPGEQPe-fDGRNEPIERGYEPFTREFDEIVTADELCEGLEL 328
WP_015088550 258 ilKDVEIS-RRLA-GYDEIn---KEEdTKLlpdcSFSKKYGKPS---NNYTAKYKEYYRIYTTEYDQVVQAEKLCSAEEL 329
WP_077805984 266 d-PAGPPD-ATES-DERAD----EQEgg-----aEEAAGDSRREp--EADDDDALVGYKAFTTAFDEEATADDLCDPDEL 331
WP_081563220 246 --DSDESA-NPEGlSSDEMetilTEGen----gyEQPAGPSAQPeeeRPCPVKGLGGYQAYTQEFDEEVHASDLCDPAEL 318
WP_088921344 260 --MQGESQ-QTDQl---------AEQ-ALD----EAPAAGVDP----TIVLMEGTQPYRAFTTDYDEVLLARDWADQAEL 318
WP_088921739 257 --EDGNAEdGSESvEPDDD--------IPErs-sEQPGSEWQTTt--GDGTRRSENDYHVYTREYDEVIRPLDLCDAEEL 323
WP_122122886 273 f-SQIPLN-MEDQ-EKPDSv-------mGSdk-sEKAGGPSQQPp--DTLADVEDASYHIYTKLFDEVVTAEQICDVNEL 339
WP_119679883 334 SRLRTLLDHQLQHLHGMIAKLANRLQRRLMAKQTRAWEFDLEEGILDAARLARVVANPIVPLSFKRENETDFRDTVVTLL 413
WP_013046776 330 DRLRTMLDRHMENVTSVVGKLANRLQRKLMAHQNRSWDFDLEEGILDAAKLHRVVTQPLSALSYKQEQDTKFRDTVVTLL 409
WP_011179906 345 DHLRQCLDKHINHLQSIVGRLANRLQRCLMAQQNRSWNFDLEQGYLDTTRLPRLIIDPMQSLSFKMESNTQFRDTIVSLL 424
WP_007089036 329 SRLRAMLDKQLANLQNVVSRLANRLQRRLMAQQNRGWDFDLEEGILDAAKLARIVSTPSTSLSFKQEQDTDFRDTVVTLL 408
WP_015088550 330 QNLRVKLDQQINHLQSFISKLANRLQRYLIAHQSRSWEFDLDDGLLDTSRLSRVIASPLYPQSYKIEKKTSFRDTVISLL 409
WP_077805984 332 IRLRQQLDQQLVNMQGVVSRLAHRLQRRLMAQQQRAWAFDQEEGILDASRLARVIVNPMLSLTYKHEREAEFRDTVVTLL 411
WP_081563220 319 DLLRERLDEQLQQTQGFVSRLAHRLQRKLLAQQQRRWHFDQEDGILDAARLPRIISNPSLPLSYKQEGKIDFRDTTVTLL 398
WP_088921344 319 QGWRDELDQHIEVHGRLVRRLATRLQRVLLARQRRHWEFDLEEGLLDSMRLARLLTDPLMPLSFKAESEMPFRNTTMTLL 398
WP_088921739 324 TRLRQTLDSHIGDLQRSVGRFANRLQRVLMAQQRRSWEFDLEEGQLDTSRLTRVLTDPLMPLTFKQESETPFRDTVVTLL 403
WP_122122886 340 DFLRNQLDQQLQEIQNIISKLANRLQRKLMSQQIRSWNFDQEEGLLDASKLTRIITNPTNSLSFKQEKSTGFKDTIVTLL 419
WP_119679883 414 IDNSGSMRGRPITIAAMSADILARTLERCGVKVEILGFTTRAWKGGQSREKWIQAGKPPQPGRLNDLRHIVYKAADAPWR 493
WP_013046776 410 LDNSGSMRGRPITIAAVTADILARTLERCGVKVEILGFTTRAWKGGQSRELWQQAGKPAAPGRLNDLRHIIYKPADVPWR 489
WP_011179906 425 IDNSGSMRGRPITVAASCADILAQTLERCGVKVEILGFTTKAWKGGKSREKWLNQHKPNNPGRLNDLCHIIYKSADTPWR 504
WP_007089036 409 IDNSGSMRGRPITIAALSADILARTLERCGVKVEILGFTTRQWKGGQSREKWVESGKPPKPGRLNDLRHIIYKAADTPWR 488
WP_015088550 410 IDNSGSMRGRPITISAITADILTRTLERCYVKVEILGFTTVDWNGGSARKRWISSGSPKQPGRLNALRHIIYKSANLPWR 489
WP_077805984 412 IDNSGSMRGRPITVAAMCGDILARTLERCGVKVEVLGFTTRAWKGGMSRERWVASGRSPEPGRLNDLRHIVYKDADSPWR 491
WP_081563220 399 IDNSGSMRGRPITTAAICGDILARTLERCGIKVEVLGFTTRTWKGGESRVKWTQDGRPPKPGRLNDLRHIIYKSADTPWR 478
WP_088921344 399 IDNSRSMLGRPIMIAAVCADILARTLERCGVSVEILGFTTVHLHGGQSTERWVEAGEPENPGRLNDLRHIIYKSADTPYR 478
WP_088921739 404 LDNSGSMHGRSIRVAAVCADILSATLERCGVRIEILGFTTGAWKGGKSREKWVAAGYPPNPGRLNDLRHIIYKAADTPWR 483
WP_122122886 420 IDNSGSMRGRPISIAAMCGDILARTLERCSVKVEILGFTTQTWKGGRSREKWLADKRPQNPGRLNDLRHIIYKAADQPWR 499
WP_119679883 494 RVRKNLGLMLREGILKENIDGEALLWAHNRLIARTEQRRILMVISDGAPVDDSTLSVNSGSYLEKHLRQVIEWIETKSPV 573
WP_013046776 490 RARKSLGLMLREGILKENIDGEALLWAHERLLGRNEDRRIMLVISDGAPVDDSTLSVNSGSYLERHLREVIAYIEGRSPI 569
WP_011179906 505 RARRNLGLMMQEGLLKENIDGEALIWAHQRLLSRREQRRILMVISDGAPVDDSTLSVNSSNYLEKHLRAVIQEIQIHSPI 584
WP_007089036 489 RARKNLGLMLREGLLKENIDGEALLWAHERLLGRSEQRRILMVISDGAPVDDSTLSVNSGNYLERHLREVIDWIQTRSPV 568
WP_015088550 490 LSRKSLGLMLREDILKENIDGEALMWAYNRIISRPEKRRILMVISDGTPMDDSTLSVNSRNYLEDHLRKIIKYIDSSSSV 569
WP_077805984 492 RARNNLGLMLREGLLKENIDGEALLWAWRRLRRRPEHRRILMVISDGAPVDDSTFSVNPSSYLEDHLRHVIGRIEGSADT 571
WP_081563220 479 RARRNIGLMLREGLLKENIDGEALLWAWKRLKHRPEHRRILMVISDGAPVDDSTSSANGPEYLDLHLHRVIHQLENDPSG 558
WP_088921344 479 SAKRSLGLMLDRDILKQNIDGESLQWAHQRLMKRPEERRILMTISDGAPVDTSTLAANPGDYLAQHLQQVVDDIQRSGHV 558
WP_088921739 484 QSRRNLGLMMRKGLLKENIDGEALQWAHGRLLQRTEQRRILMMISDGAPIDDSTLSTNPGRFLEKHLRHVISQIERQGEV 563
WP_122122886 500 RAKRNLGLMLKDGLLKENIDGEALFWAWQRLKTRVEKRKILMVISDGAPVDDSTLSTNGSEYLENHLKRMIRKIENRAEI 579
WP_119679883 574 QLVAIGIGHDVTRYYRRAVTIVDAEQLGGTMMEKLAELFEE 614
WP_013046776 570 ELLAIGIGHDVTRYYRRAVTITDVDQLGGAVVGQLTDLFDE 610
WP_011179906 585 ELIAIGIGHDVIRYYQRAVTVMNAEGLADAITKQLTALFSD 625
WP_007089036 569 ELLAIGIGHDVTRYYQRAVTINDPEELGGTMLRELSDLFDE 609
WP_015088550 570 ELVAIGIGYDVKQYYRRATTIVDAEQLGDTIMKHLILLFNK 610
WP_077805984 572 ELVAIGIGHDVTRYYRSSVTLTNAEELGGTMMQKLTELFST 612
WP_081563220 559 ELLAIGIGHDVTRYYANSVTISSAEDLGDTMVAQLTALFAP 599
WP_088921344 559 ELLAIGIGHDVSRFYEHAVSIFDARQLGPVMLNELESLFRQ 599
WP_088921739 564 ELVAIGIGHDVRQYYSRATTIHDVTQLADVMTSQLVELFSA 604
WP_122122886 580 ELVAIGIGHDVTRYYKHAVTITKAEELGGTMIHELTKLFDE 620
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