Conserved Protein Domain Family
NhaA

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COG3004: NhaA 
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 442241
Aligned: 548 rows
Threshold Bit Score: 157.552
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_048529130   1 M----YRVWNFLTNYSLLLIFGALIALVWANLDliapvagdphywADTYHYFVDFVIWDhapigeyhaaeiaasdpafae 76 
WP_005811106   1 Mst-qKKTINFLQEFSIPLILGVLIALVWANLA------------PENYHHFVHNEII---------------------- 45 
WP_011365771   1 M----RKPINLLREFSVPLIAGVITALAWANLD------------PRGYDALIHQPSF---------------------- 42 
WP_011734026   1 M----KRHLNMLREFSIPLISGVIVALVWANIS------------PESYQHFDHDRNF---------------------- 42 
WP_011736820   1 M----KKHLNLLREFSVPLVAGVVVALFWANLD------------PAGYRAFDSTPFW---------------------- 42 
WP_013624386   1 MakqkRKTISLLREFSIPLISGVLIALIWANAA------------PASYHHFVDNKIW---------------------- 46 
WP_077024200   6 L----DLAAQFLFENSLFLIGGAIAALVWANVD------------LESYHQFLHTSLIP--------------------- 48 
WP_083732281   1 M----KKTIQTLQEFSIPLILGVICAMLWANLS------------PDSYSALVHTPVYLlgtifnh-------------- 50 
WP_108435383   1 M----YRVSPFVRRFAWALLGGIALATVWVNLS------------PESYYDVIEWRLIDrpl------------------ 46 
WP_128746711   1 M----AMWLNRFREYSLPLILGVVTALIWANLS------------PETYEGAVHGTIA---------------------- 42 
WP_048529130  77 mvaagaevytgadGaqfvF-GEGSRTLTLHYLVNDLLMAFFFAIAAKEVWEAVILEnGSLRGKKAATPLFATAGGMFGPI 155
WP_005811106  46 ------------------------GHISLHFFVNDIFMVFFFAMAAIEITQSLLPGgSLNPLKRAINPLMATLGGVLGPA 101
WP_011365771  43 ------------------------GGVSLHFLVNELFMVLFFGIAAAEITQSCLPGgDLNPPRKAVNPLLATLGGVIGPV 98 
WP_011734026  43 ------------------------GPFSFHFIVNDFFMVLFFGIAAAEITQSCLPGgDLYPLRKAVNPLLATIGGVVGPV 98 
WP_011736820  43 ------------------------GSLSFHFISNELFMTLFFGIAAVEITQSCMPGgDLNPISRAVNPLFGTLGGVLGPV 98 
WP_013624386  47 ------------------------GDFTLHFFVNDLFMVFFFAIAAVEITQSLLPGgDLNPLKRAINPMMATLGGIAGPA 102
WP_077024200  49 --------------------GSHEVGYSLLHVVNDGLMAVFFAMAAKEVWESLLPGgPLSKWKTAATPLMATLGGVVMPT 108
WP_083732281  51 ------agghgavH----A-AGWDHYLTLHFLVNDIFMALFFGIAAKEITEACLPNgALNPVSKAINPLFGTVGGVVGPI 119
WP_108435383  47 ---------------plwIsGD-AVIVTPMTLVSDVLMSLFLFFVGKELWEALVLArGALAGRRALLPAGAVAGAIAGSV 110
WP_128746711  43 ------------------------GPVNVHFLVNDVFMVFFFAVAGIEIVNSLSPGgDLNPIKKAITPLLATAGGIIGPI 98 
WP_048529130 156 AVYLGLAAvmGSetysAVANGWAIPTATDIAFSYLIGRLVfGAGHPAVRFLLLLAIADDAAGLIILAVFYPSg--ELAPE 233
WP_005811106 102 LVFLGLNAliGSp---eFARGWGIPTATDIALAWLVARVVfGAQHAAVSFLLLLAIVDDGIGLMIIAFFYPDpanPVAPL 178
WP_011365771  99 LVYLSLNAviGDp---tLTKGWGIPTATDIALAWLVARLVfGAGHPAVSFLLLLAVADDAIGLAIIAVFYPDpvhPTEPM 175
WP_011734026  99 LVYVVLNAlmGDp---sLLRGWGIPTATDIALAWLVASLVfGKRHPAISFLLLLAIADDAIGLAIIALFYPDpnlPAAPQ 175
WP_011736820  99 LVYLGLNAlvGLp---eLRNGWGIPTATDIALAWLAARMVfGPGHPAVSYLLLLAVADDAIGLAIIALFYPDpnhPVVAA 175
WP_013624386 103 LLYLALNTfmGSq---eLVRGWGIPTATDIALAWLVARLVfGAAHPAVSFLLLLAIADDGIGLIIIALFYPDpanPVVPV 179
WP_077024200 109 FVYITGCLivGQw--dTLGRGWAVPCATDIAFSYLIARIVfGAGHPAIAFLLLLAIADDAAGLLILAVAYPQe--ALQPQ 184
WP_083732281 120 GVFLGLNAvfGTs---vWANGWGVPTATDIALAWLVIKFLfGARHPAVSFLLLLAVADDAIGLGIIAIGYPDpnhPTQWM 196
WP_108435383 111 SVWLLYAAlfERaveaVPGAGWPVPIGSEIVVGYVVGRRVfGAGHPALHLLLLISIASNILGTLMLGVAYPAa--GLKLL 188
WP_128746711  99 VVFFSLNElmGDp---tFLNGWGICTATDIALAWLLARMVfGKDHPAVSFLLLLAVADDAIGLIIIAVFYPDpnaPVEPL 175
WP_048529130 234 WLLLSLGAALGVFLLanwlpRRldqgnqdrpastwvRKTLSFWPYLLA-GCASWYGFMMSGLHPALGLLPIVPTIPHADR 312
WP_005811106 179 WLLLTVAGMLVAYLL-----RR--------------KNVQSYWPYIILgGILSWAGLYLAHIHPALALVFIVPFLPHPPR 239
WP_011365771 176 WLFLTVAGIVAAYIL-----RG--------------ARAKSYWPYVLVgGGLSWTGLFKAHLHPALALVFIIPFLPHPPR 236
WP_011734026 176 WLVLVLSGMGAAALL-----RR--------------GNAQSYWPYIILgGGLSWAGLFMAHLHPALALVFIVPFLPHPHR 236
WP_011736820 176 WLLLTLLGMLVAWGL-----GR--------------RRVRSYWPYILLgGSLSWIGLHQAHLHPALALVFIIPFLPHRLR 236
WP_013624386 180 WLLCTLAGMLIALAL-----KK--------------GKVKSYWPYILLgGALSWTGLYRAGIHPSLALVFIVPFLPHSPG 240
WP_077024200 185 YLLGAVGAVAWGLLL-----RR--------------LGVRSFWVYLLGpGVLSWLSFHYAGIHAALGLVPIIPTLPHAAH 245
WP_083732281 197 NLLWCLPGIGIAYGL-----RL--------------NKVMNWVPYIAIgGAFCWWGLYSAHLHPALALVFVVPFLPGPKH 257
WP_108435383 189 WLLAPLAASFLVWRLygrpdARgate-------rdrRRAQALWPYVLA-GVASWIGVAAAGLPPELGLLPVLPAIPHADR 260
WP_128746711 176 WLLLIVLGMLVAAHL-----NK--------------RQVQSYIPYIFGaGTICWIGMLNAHLHPALSLVFIIPFLPRQGQ 236
WP_048529130 313 A----FGifseaEQ----YLTDLLNMIEHALKHPVEIVLFFFGLFNAGVEFSSIGPATWLVLAGLLIGKPVGILLFGWVA 384
WP_005811106 240 E----EFglfedDP----QDHSTLKTFEHEWKIFVDFGLLLFGLTNAGVEFSEINTLTWLVLIALVGGKTIGIFLMGSLA 311
WP_011365771 237 E----SAhlfeeNP----RDTSPLARFEHDWKIVVDFGLFLFGLANAGVRFSSVGTATWLVLTALLVGKTAGILTMGSLG 308
WP_011734026 237 E----KKhlfeeDM----RDLSPLASFEHEWKVMVDFGLFLFGLANAGVTFGSIGAATWLVLASLVIGKTGGIFFMGWLG 308
WP_011736820 237 E----SRhlfddDP----GDRSPLAQFEHEWKVVVDFGLFLFGLANAGVEFSSIGTVTWLVLVSLLVGKTVGIFGFGLLA 308
WP_013624386 241 E----KAhlfedDP----EDYSTLRRFEQEWKFFVDMGLFLFGLTNAGVEFSAVSTVTWLVFLALLFGKTAGIFLLGSLA 312
WP_077024200 246 D----PGlfaedEQ-----DHDTLSEFARWWKNPVELILGLFGLVNAGVVFSNTGPATWLVLSGLLIGKPLGITLFTFLG 316
WP_083732281 258 D----LGlfvddEDysegHHHSPLEQFEHSLKLFVDFGLFFFALVNAGVSFGEINGLSWIVVAALIVGKIVGITGFSAFA 333
WP_108435383 261 S----FGlfaeaEE----LLHDPLNRLAHLLAAPLAVVLFLFGLTRGGIDLQAWAPTTATVLAAMWIGKPLGLVAGALLA 332
WP_128746711 237 SlegvDMhgvndAP-----EYSTLSCFEHHISPIVDYGLFFFGIANAGVEFSSVSNLTWIIFASLVVGKTLGISLFTWLA 311
WP_048529130 385 AKPLKLGIPQGMRIIDLVVIGFVAAIGFTVSLFVASVAFNAg-PVQDAAKMGALFSFAAALVAIASGKIFrVEKQN 459
WP_005811106 312 TV-IGFPFPKGMGYKELLVAGVIAAMGLTVALFVSGVAFIDp-GLQGAAKMGALFSAVAAVIAFALGKVLgIKKVK 385
WP_011365771 309 KA-LGFPLPDRVGFKELALTGLVAGMGLTVALFVAGVAFVDp-DIEGAAKMGALLSGGVLPVAVALGRILkVRRIP 382
WP_011734026 309 RR-LGYPLPSRVGGKELALVGLIAGIGLTVALFVAGEAFTDp-ARQGAAKMGALMSAGCAVLALAAGRIMnVKRIT 382
WP_011736820 309 ER-LGFRRPRGMKRRDLLVAGVVAGTGFTVALFVSGSAFSDp-VIQAAAKMGAMFSLAAALIGMLLGQLLrIRKVH 382
WP_013624386 313 SF-LGFPLPEGMRHRELLVAGLIASIGLTVALFIAGVAFSDp-GLQGAAKMGALWSVSAVIIAVSAGRLLgIERKT 386
WP_077024200 317 EKLFHLERPDGMTYGHIVTLGMVAAIGFTVALFVSTAAFNEpgAIQDSAKMGALASFAAAIIAIPLGRALkVKSAA 392
WP_083732281 334 AK-IGFPLPAGMNTGHLVVTSAVAGLGLTVALFVCGQAFVDp-SLQAAAKMGAVFSVGAAGVAFALKKLLnVQDDV 407
WP_108435383 333 ARIFRLPMPAGVRIRDLVLIAVISGIGFTAPVLAVDTALPGg-AMAEAARLGLALSMLAAFVALALSRVM--RR-- 403
WP_128746711 312 TL-WKFNLPEGMSGRDVFLAGVVGGMGLTVALFVVTPAYTDp-ALQGAAKMGALFTVFVFILATVLARILnIKKIG 385
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