Conserved Protein Domain Family
PRK04004

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PRK04004: PRK04004 
translation initiation factor IF-2; Validated
Statistics
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PSSM-Id: 235195
Aligned: 79 rows
Threshold Bit Score: 788.606
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
145590869   2 AGVRSPFVVVMGHVDVGKTLLLDKIRGTSVAYREPGMITQHIGMSFVPWQAVEKFSGPLVDRlrlrGRIWIPGFLFIDTP 81 
124486335   3 EHIRTPIVCVLGHVDHGKTSLLDRIRGSKVVAGEAGAITQHIGATLIPFDSIAKMSGDLGR-----LKTSVPGLLFIDTP 77 
88603730   16 PHIRTPIVCVLGHVDHGKTSLLDRIRGSSVVAGEAGAITQHIGATIVPIDSIMSMSGGMKN-----LNISIPGLLFIDTP 90 
169236610  11 GDLRTPIVAVLGHVDHGKTSLLDKIRGSAVIEGEAGAITQHIGATAVPLDTVSEVAGSLVDP----TEFDLPGLLFIDTP 86 
13541284   12 KKLRQPIVCVLGHVDHGKTTLLDIIRGTAVANKEPGGITQRIAATTVDINKILKATEKLNN-----KGMKIPGLLFIDTP 86 
16082134   12 SKLRQPIVCVLGHVDHGKTTLLDLIRGTSVASKEPGGITQRIAATTVDISRILKETEKLNT-----KGLKIPGLLFIDTP 86 
126178411   5 STIRTPIVCVMGHVDHGKTSLLDRIRGSSVVSTEEGEITQHIGATLVPIDAVTRMGGALSK-----VSVNVPGLLFIDTP 79 
48478356    5 KSLREPIVCVLGHVDHGKTTLLDDIRGTSIAEKEAGRITQKIGATEISYNILEREIKTAFKN----IPIKIPGLLFIDTP 80 
154151833   4 PKIRTPIVCVMGHVDHGKTSLLDRIRGSSVVASEAGAITQHIGATIVPIEAIRKMSGSMEK-----IPINIPGLLFIDTP 78 
219851012   8 AKIRTPIVCVLGHVDHGKTSLLDRIRGSSVVSSEAGAITQHIGATLVPIEAIRAMSTSMQK-----IPVTVPGLLFIDTP 82 
145590869  82 GHAAFSNLRKRGGSVADLAILVVDITSGLEDQGVESLKLIQSRGVPFVIAANKLDRIYGWKSVENRPFLFAVEDQEWHAV 161
124486335  78 GHHAFTTLRARGGALADIAILVVDVNEGFKQQTIEALQILRTCKTPFVIAATKLDKIPGWRPTPNASFQKAYKNQSERVQ 157
88603730   91 GHHAFTTLRARGGALADMAIVVVDITEGFQPQTIEAIQILRNCKTPFVVAATKLDRIPGWRSTEKSPFLKSFAAQNERVT 170
169236610  87 GHHSFSTLRSRGGALADIAILVVDVNDGFQPQTEEAIRILKDTGTPFVVAANKIDTTPGWNPNPDAPVQGTYDDQSDRVR 166
13541284   87 GHVAFSNMRARGGALADIAVLVIDINEGIMPQTVESIDILKKFKTPFIIAANKIDLIPFFTDVKTNLFTEFIRKQRQEYV 166
16082134   87 GHVAFSNMRARGGALADLAILVIDINEGIMPQTVESIDILKKFKTPFIIAANKIDLIPFFTDVKTNLFTEFIRKQRQEYV 166
126178411  80 GHHAFTTLRARGGALADMAIVVVDINEGFRPQTIEALQILRNYKTPFVIAANKVDRIHGWRVQENQPFLKTFAQQNERVQ 159
48478356   81 GHVAFSNMRSLGGALADIAILVIDVNEGLKPQTIESIDILKKFKTPFIIAANKIDAVPYFVNTSNTSFANAIKMQRREYI 160
154151833  79 GHHAFTTLRARGGALADMAILVVDISQGFQPQTIEALQILRNCKTPFVIAATKVDRIHGWRINKDESFLSSFGKQNERVK 158
219851012  83 GHHAFTTLRARGGALADMAIVVVDINEGFQPQTIEALQILRGCKTPFVVALTKIDRVHGWRVVENAPFLTTFAQQNERIQ 162
145590869 162 ATLEERIGKLIEELSKFGIEADRYDRVRDFTKQVPIVPTSAVTGEGIADLLLVLAGVSQRFIPKEKLQVGEGPARGVVME 241
124486335 158 TECENRVYELVGKLSDMGFNSERFDRVSDFQRNLVIVPVSSMTGEGIGDLLMIMIGLAQRYLTEGLKTTTSGPGVGTVLE 237
88603730  171 LLVETKVYDIVATLAEHGFSSERFDRVSDFARNLAIVPVSAHTGEGIPDLLMVLIGLAQRYMEEALTLTVDGPGSGTVLE 250
169236610 167 SDLDDALYELIGEMSDAGFSSDLYWRVQNFQKNVGVIPVSAETGEGVPDLLTVLMGLAQRYMKSEMEVTIDGPGAGTVLE 246
13541284  167 NELDARIYNIVNKLYEYGLNSDRFDRISDFTKTIAIVPVSAKKNIGVPEILMVLAGLAQRFLESEIEY-KDINGHATIIE 245
16082134  167 NELDNRIYSIMNKLYEFGLNSDRFDRISDFTKTIAIVPVSAKKNIGVPEILMVLAGLAQRFLEREIEY-RDINGHATIIE 245
126178411 160 GMVETKVYELVGKLSDLGFNSERFDRVSDFARNICIVPTSALTGEGLPDILMVLIGLAQRYMTESLKVSADGPGAGTVLE 239
48478356  161 EELDNRIYKLISDLYTYGINADRYDRISDFSKTFAIVPVSAKLKIGIADILMVLSGLAQKFLENEIRL-TYEKTLGTVIE 239
154151833 159 TDIETKTYEIVGKLSDLGFSADRYDRVSDFQRNLAIVPVSAHTGEGIADLLMIMIGLAQRYMGEELKLSAEGPGEGTVLE 238
219851012 163 EFMETRHYEIVGKLSDLGFNCERFDRVQDFARNIAIVPISAHTGEGIADLLMVMIGLAQRYMEQSLAMSVDGPGCGTVLE 242
145590869 242 VKEERGLGVVADAIIYDGRLRKGDVVVTAGLEGPKEAKVRMLIMPKPLEEMRdPEDRFMAVEEVKAAAGVRIVADGLEGV 321
124486335 238 VKEEKGLGTTLDVILYDGIISVGDEIGIAGSDGALSTKVRALLQPRPMKEIL-IEDQFMRVKSVVAAAGVKISAPNLESI 316
88603730  251 VKEEKGLGATIDVILFDGTIRVGDEIAIATTEGVQTTKVRSLLQPRPMQEIL-VEDRFLRVKEVVAAAGVKVSAPGLDQV 329
169236610 247 VKDEQGFGTTVDVILYDGTIRSGDTVVVGAQPEPIVTDVRALLKPGDLAEMR-TEKRFGNVDRMQAAAGLKVAAPDLDDA 325
13541284  246 VRREESAGIALDAVLYQGTISVGDTVAVNTKTGPVTTKVKALFVNTGK-----SQRSLKEVETVSAAEGIRVLISDKLDV 320
16082134  246 VRKEESAGITLDAVLYQGTISVGDSIAVNTKNGPAVTKVKALFVNTGK-----GQRALKEVKKVSAAEGIRVLISDKIDV 320
126178411 240 VKEERGLGMTLDLILYDGTLKVGDEIVVAGNDQIIETKVRSLLKPRPMSEIL-IEERFERVKSVTAAAGIKVAAPKLDGV 318
48478356  240 VKIEESIGITLDTILYQGMLKRGDTIAVNTSNGPARTRVKAILVN--------SNRGLKESEKVVAAAGIRVLITDKIPV 311
154151833 239 VKEERGLGTTLDVILYNGTLSVGDEIAMASQDDVVTTKVRSLLKPRPMKEIL-IEDRFERVKSVVAASGIKVSAPGLEKV 317
219851012 243 VKEERGLGPTLDVILYDGTLSVGDEIMLASEDGVITTKVRSLLKPRPMKEIL-TEERFERVKSVVAASGVKVAAPNLDRV 321
145590869 322 VAGAPLLAVWSlQDLPNarrLVGEEISEIKIESDREGVIVRADTFGTLESTVLFLRQQGVPVRKADVGPPTHKDVVEAVL 401
124486335 317 VAGSPIRVIR--GDHDEvlaKINEEMQEINIKLSDVGVSVRADTIGALEALSNELDAKNIPIMRASVGPLSRRDLIDISV 394
88603730  330 IAGSPVRVIG--EDPEEvktSIAKEMTEINVSLSPEGLIIKADTIGALEALCKELTAHEIPVMRAEVGQVSRHDVIEAET 407
169236610 326 MAGAPIRVVGD-RDVADvvtEVEAELAEVAVETGEEGIVVKADTLGSLEALVSALEEAEIPVMSAEVGDVAPRDVAMATT 404
13541284  321 ISGSPLIVVK--GNMEQvmkEI-EEASKVDIPLDENGIYVKAEAIGSLEAISYELNKQGIKIRAAAVGDITKRDVMDVQT 397
16082134  321 ISGSPMIVVR--DNLDQvmkEIEEE-SKVDIPLSEEGIYVKAEAIGSLEAISYELNKQGIKIKQAQVGDITKRDIMDVST 397
126178411 319 IAGSPLRAVRS-GNRDEvieQVRREVQDIEVNLSDVGVIIRADTIGALEALSKELEGHQIQVMRATVGPVTRHDVIEAGT 397
48478356  312 IAGTSMIKIDEnTSEDEafkTIINESKPN-IKISEHGVTVKAEALGSLEAIAYELEQASINIRSAEIGDITKHDVTDVST 390
154151833 318 IAGSPLFVTR--GNMDElaaRIRKEMQEIHVNLAEEGIVIKADTIGALEALCKELESKEIKVMRAQVGPVSRHDLIDTET 395
219851012 322 IAGSPLRGVR--GDREAvatQIRQEMEEIHVKLVEDGLVIKADTIGALEALCQELENKEIGVMRAAVGPVSRHDLITAET 399
145590869 402 SrrKNPAFGVILAFNVKIPPDVEKEATSSG----IKIIRGEILYRIFDEYLKWSQEVKTKTIEQILSQLTRPGKIQILPG 477
124486335 395 I--KEDLFKVALCFNVPLLPDAEAMVRDEEv--dVKIFSNRVIYKLLDDYLEWRDEMIRAKEAKQFETVVLPAKFSILPG 470
88603730  408 I--KDPLYRVLIAFNTPVLPDAQDLLKEPAyaemIQFFSGNVIYHILEDYLEWRNNLKRIMDQKRFEKIIFPAKILVLPG 485
169236610 405 V--DSEKHRVLLGFNVDVLPAAAENAERES----VRVFNSDVIYQLVEDYEAFVDAQEREQKEAVFDNIVRPARFRILKD 478
13541284  398 L--QDPLNRIIIGFNVSILPEAKDAIESSD----VGVITGDIIYKIVEDTQKWIEERKKQLSQKRKEAMPVPAKIRILPQ 471
16082134  398 L--PDPINRIIVGFNVSVLPEARDAMSSSD----VSIVTGDIIYKIVEDTQKVMDERKKMLLQGRKMSMPVPSRIRILPQ 471
126178411 398 I--KDPLYSAIIAFNTPVLPDAVDALADTAms-hVSIFEGGVIYQLIDDYVEWRDEKKQELERQKFEKLIMPAKIRILPN 474
48478356  391 L--NDPLDRIIIGFNVSVLDDAVQEAASSD----IGIITGNVIYSLVDDAQKWLAKRKHDLEEQRKSNIPVPSKIVIMPE 464
154151833 396 I--KNPTFRVLLSFNTPILPDAADMIKDPLyt-qVKVFSGQVIYQLIDQYVAWRDEQKRIAEKAQFEHVMMPAKIRLLPD 472
219851012 400 I--KNPLYKVVLAFNTPLLPDAADIVKETKq---MKVFSGRVIYQLIDAYLLWRDQQKRAMEQQKFENIIIPAKIRIMPN 474
145590869 478 FVFRRSDPVIVGVKVLAGTIKPGVTLVK-DG---REVGKIMQIQKQGKPVNEAAVGDEVAISIQGDVmVGRQIKEGDVLY 553
124486335 471 CVFRMSGPAVVGVRVLGGTLRPKVSIATrDG---KIVGEIKQIKLNKETIGEAKEGAEVAVSIDGVT-IGRQIDVGETLY 546
88603730  486 CVFRQNNPAVVGVRILSGTLRTGVNLVRrDG---KKAGTLKSMQLRKENIQEAHAGDEVAISIEGAT-VGRQFDVEDELL 561
169236610 479 HVFRQNDPAVVGVEVVSGTLKRNTPVGGiEGndlDRAGIVKGIQDQGEDVDEARAGNRVSVSIDGPT-VGRDIKEGDELW 557
13541284  472 YIFRASKPVIVGIRVETGQIKVGDNLIRsDG---KYAGTIKSIRNDEVSVRYQDAPAEVAVAIDNVT-LNRQIFPDDVLY 547
16082134  472 YIFRASKPVIVGVRVETGQIKVGDNLIRgDG---KYAGTIKSIRNEDVSVRYQDAPAEVAVAIDNVT-LNRQIFPDDVLY 547
126178411 475 CVFRQSNPAVVGVRILGGKLQSGVDLALpNG---KKIGRIKQIQAKNETVQEAEAGKEVAISIEGPT-VGRQINVDDDLY 550
48478356  465 YIFRAAKPVIVGIKVISGRVKVGDTLIDdNN---KYAGTIKSLRDGDVSRQFVDAPAEVSCAIDGVV-LNRHIFPGETLY 540
154151833 473 CVFRQSNPAVVGVRVLGGKLRADVDLVKtDG---KKIGHLKTMQLRQESIKEADAGLEVAISIEGAT-VGRQLNVGDDLL 548
219851012 475 CVFHQSNPAVVGVQVMEGKLRTDVNLVHlDG---RKVGHLKTIELSLENVHEAEEGSEVSIAIEGAT-IGRQADVGDILF 550
145590869 554 VYVPDEQAREWLFKYKQYLRDDEKKALEEFLKTRksaHQ 592
124486335 547 VAIPERHVKVLETEMLSHLNAGTVEALEEYTGIF---RK 582
88603730  562 VGIPERHVKVLETEMLSHLNEDAKEVLNEYTRLF---RK 597
169236610 558 VDLPEKHAKVLDQELTSDLPADEREALKSYLDIM---RK 593
13541284  548 VDIPESVVKELR---KAPMEKEIMDTLEEIIKIK---RK 580
16082134  548 VDITENVVKELR---RAPMEKEIMDTLEEIIRIK---RK 580
126178411 551 VDIPERHVKVIEREVIDHLSPSLRETLEEFTTLK---RR 586
48478356  541 VDIPENVAKQLRSE---KLDDNIMKTLDEITKIK---RK 573
154151833 549 VDLPERHVKVLEREMLKNLNISTQEVLAEFVAIR---RK 584
219851012 551 VDLPERHVKVLEKEMLSHLTAGTQAVLEEFTSMK---RK 586
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