1KDT


Conserved Protein Domain Family
Cytidylate_kin

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pfam02224: Cytidylate_kin 
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Cytidylate kinase
Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.
Statistics
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PSSM-Id: 280401
Aligned: 12 rows
Threshold Bit Score: 261.47
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KDT_A   8 ITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHH------------------------------------- 50  Escherichia coli
O51154   3 IAIDGPSASGKSSIARELGVRLNYKFISSGHLYRIITLIAQRSlm----------------------------------- 47  Borreliella burgdorfe...
O83303  37 IALDGPAGSGKSSVCRLLASRLGAQCLNTGSFYRAFTLAALRRvselavqacspspdpdaavgcaavphatnldtsyapl 116 Treponema pallidum
Q9ZD27  17 ISLDGPAASGKGTVGLILAKKFSLKYFQSSIVYRQLAFNCINQ------------------------------------- 59  Rickettsia prowazekii...
O67907   3 IAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKF------------------------------------- 45  Aquifex aeolicus VF5
P75308   5 IAIDGPSSSGKSSVAKTVARQLGFEYFSTGKMYRAFAYVM---------------------------------------- 44  Mycoplasma pneumoniae...
O84458   3 ITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ-------------------------------------- 44  Chlamydia trachomatis...
P43892   3 ITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQR------------------------------------- 45  Haemophilus influenza...
Q55074 292 IAIDGPAGAGKSTVTRQVADGLGLTYLDTGAMYRALAWLILDQ------------------------------------- 334 Synechocystis sp. PCC...
P38493   7 IAIDGPAAAGKSTVAKIVAEKKSYIYIDTGAMYRAITYAALQE------------------------------------- 49  Bacillus subtilis sub...
Q49885   6 VAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRA------------------------------------- 48  Mycobacterium leprae TN
P9WPA9   9 VAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRA------------------------------------- 51  Mycobacterium tubercu...
1KDT_A  51 ----HVDVASEDALVPLASHLDVRFVSTng--nlEVILEGEDVSGE-IRTQEVANAASQVAAFPRVREALLRRQRAFRE- 122 Escherichia coli
O51154  48 ---nSCDFISEDSLLNLILENDISFNNF------AFLLNGENVENQ-ILNDKIDFQVSFYSSYVGIRNIVNKKLREVVKf 117 Borreliella burgdorfe...
O83303 117 taqkKVALFDEAYWVSFARTVALSYRAG------VMYVGEENVESL-LRSDEVESAVSYFAAMPAIRAIMTGKIRSAVC- 188 Treponema pallidum
Q9ZD27  60 ----QIDITDIDAVIALSKELKL------------------DNNID-LENEDIGDIASQIAVISDVRNNLNENLINLVKt 116 Rickettsia prowazekii...
O67907  46 ----KVPIQDIDKLFSLPVKVVPKIGKT------EVYIEGKPVNEEdLRSEEVGKRASELGSIPEFRERINKLFKEIIN- 114 Aquifex aeolicus VF5
P75308  45 ----QVNRLDVNLLLKVINQINWRFEHE------KVFYNNADISEV-ILNQEIAQLASNLATNPEVRKMAVLRQQALAK- 112 Mycoplasma pneumoniae...
O84458  45 ------PDWQEVPLEDFLASPPFSFSFSkds-plQAFYGDRLLTSE-LSSQEVANFASLFSKEPLVRAYMQTLQKQYAT- 115 Chlamydia trachomatis...
P43892  46 ----KTDLTNETDLAELARHLDIQFIPQng--evSILLAGMDVSRL-IRTQEVADAASKVAVFQKVRSALLQLQQDFAK- 117 Haemophilus influenza...
Q55074 335 ----GIAPEDEPAVAELTSGAEIELMPRpapqltGVKVNGQDVSDA-IRTPAVTQLVSTIAAQGAVRAKLLKLQRKYGD- 408 Synechocystis sp. PCC...
P38493  50 ----NVDLTDEEKLAELLKRTDIELITTkd--gqKVFVNGTDVTEA-IRTDEISNQVSIAAKHRSVREEMVKRQQQLGE- 121 Bacillus subtilis sub...
Q49885  49 ----GIDPADAAAIGESVWKVQMLSDHD------RYFLGGEDVSSE-IRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEg 117 Mycobacterium leprae TN
P9WPA9  52 ----GADPSDIAAVETIASTVQMSLGYDpd--gdSCYLAGEDVSVE-IRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEg 124 Mycobacterium tubercu...
1KDT_A 123 -LPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKgf-sVNFERLLAEIKERDDRDRNRAVAPLVPAADAL 200 Escherichia coli
O51154 118 sDDNYIIEGRDITTVVFPESEFKIYLDASVKVRALRRYKQRNGN----ETLEELERTLKRRDDVDKKKQYGKLKLSKGVF 193 Borreliella burgdorfe...
O83303 189 -GARVVCEGRDLTTVVFVDADLKCYLDASIEARVARRWAQgt----srLSKQELEQRMRARDAHDRARTVGGLRCAPDAL 263 Treponema pallidum
Q9ZD27 117 -TPRIIMEGRDIGTVVAPDADLKIFITASPYVRAIRRYNQLQAKgk-tCILDEIIQQIILRDKRDKERKAGPLLPALGAF 194 Rickettsia prowazekii...
O67907 115 -NKQMVVEGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELgy-eVSFEEILQKILERDKRDMERPKYPFKPAEDAV 192 Aquifex aeolicus VF5
P75308 113 -NTNIVMDGRDIGTVVLKDAQLKYFLDAKPEIRAQRRAQDLGIAydsdKAFQELVAEIKHRDAVDTSRTADPLVQAPDAI 191 Mycoplasma pneumoniae...
O84458 116 -VGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQGsl---sKEALMAELIARDQADQQRECDPLVIPQDAT 191 Chlamydia trachomatis...
P43892 118 -NDGLIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNKgi-nGNFAQILAEIKERDFRDRNREVAPLKPADDAL 195 Haemophilus influenza...
Q55074 409 -QGGIVAEGRDIGTQVFPNAELKIFLTASVQERARRRLKDFEAQgnqaVDLAQLEADIAHRDHLDSTRAIAPLQKAVDAV 487 Synechocystis sp. PCC...
P38493 122 -KGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRYEENVKKgf-dVNYETLIEEIARRDKLDSEREVSPLRKAEDAL 199 Bacillus subtilis sub...
Q49885 118 -RGSVVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASgs-aDDYDRVLAEVRRRDHLDSTRAVSPLYVAQDAM 195 Mycobacterium leprae TN
P9WPA9 125 -PGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAgl-aDDYDGVLADVRRRDHLDSTRAVSPLQAAGDAV 202 Mycobacterium tubercu...
1KDT_A 201 VLDSTTLSIEQVIEKALQYARQ 222 Escherichia coli
O51154 194 YLDTSYKGLDDVCNIIIEKFNL 215 Borreliella burgdorferi B31
O83303 264 YVDTSCLTIEEVCERIAREAHR 285 Treponema pallidum
Q9ZD27 195 IIDTSKLSAIEIVEEVTNYIKN 216 Rickettsia prowazekii str. Madrid E
O67907 193 IIDTTRKSVEEVVEEVLKIIHE 214 Aquifex aeolicus VF5
P75308 192 YIDSSNLTFQQVVELMVQQART 213 Mycoplasma pneumoniae M129
O84458 192 VIDSSDLTISQILEKILPLIPS 213 Chlamydia trachomatis D/UW-3/CX
P43892 196 LLDSTTLSIDEVIDQALAYIQR 217 Haemophilus influenzae Rd KW20
Q55074 488 EIITDNLTIAEVVETIIELYKK 509 Synechocystis sp. PCC 6803 substr. Kazusa
P38493 200 EIDTTSLSIQEVADKILEAVEQ 221 Bacillus subtilis subsp. subtilis str. 168
Q49885 196 IVDTSKMAEAEVIAHLMDLVKQ 217 Mycobacterium leprae TN
P9WPA9 203 IVDTSDMTEAEVVAHLLELVTr 224 Mycobacterium tuberculosis H37Rv
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