6WVK


Conserved Protein Domain Family
HelD

?
COG3973: HelD 
DNA helicase IV [Replication, recombination and repair]
Statistics
?
PSSM-Id: 443173
Aligned: 268 rows
Threshold Bit Score: 342.23
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6WVK_H          1 MNq-----qD------KEWKEEQSRIDEVLKELEKKERFLEtsagglkhdiiglrksfwedvkvnfDDAHEAI------- 62  
WP_012199658    1 MEl-----dR------YSREYEEQHLKECVNVIEQNIEKYA-------------------------KQEAILAgdikemy 44  
WP_012742026    2 MGt-----eNdl--pgISLKDEQRQLQNIIGIAQDNLDRAK-------------------------ESVKKLTddledlr 49  
WP_013372623    1 MEnk----fQ------SAYQEEQHRLSLAMEEIDRRLERLR-------------------------NTPVYTG------- 38  
WP_014081292    1 MDkrstseeQksgylgLTRADEERHLADVISVAQQNLERAG-------------------------ADIRKVNedladll 55  
WP_014911307    2 TSv-----fP------DVHEEEAAHLARTLELLESRIEALT-------------------------GALDGHDtdyndvk 45  
WP_000065177    1 MS--------------NIFEDELQKMKDTLHTMDEQLDKLE-------------------------KTPVYYG------- 34  
WP_087455565    1 MEse----iQ------SAYQEELQRLEHTAAEIDRQLQTLE-------------------------TVPRYYG------- 38  
WP_096551757    1 -------mdK------KELQLEQKKLDETIQRIEDQTYYIW-------------------------ELlerkn------- 35  
WP_123043829    1 -----------------mYEEERSRLNHTFEEIERQHSAIG---------------------------PVYRG------- 29  
6WVK_H         63 ETMa--SIK---------QQ--AelLSDREHNHRRMDQQLKRIHQLKKSPYFGRIDFiengeE-QAERIYIGLASCLDEk 128 
WP_012199658   45 DHYhddSPEiy----------tE--LSNTMTMHGSIKMALNKNRKALQKPYFGRIDYldhedD-KKSTLYLGKNGVMKS- 110 
WP_012742026   50 DVYeaqDk----------EGlvL--WNNATAQLHENERNIVRCEKARKKPYFGRIDFkdprqK-SQESYYIGRVGIAKN- 115 
WP_013372623   39 ----------------------H--DFTEQVLESAREEKRQALAKSSQEPYFGRMDFdergrG-QRKPLYIGKIGVEREe 93  
WP_014081292   56 ETYdvkDk----------EGlaL--WNNATARLKENEYDLIRYEKARKKPYFGRIDFkdgisQ-EEETCYIGRAGIAKN- 121 
WP_014911307   46 SYMsdnRGEidptemyqnEL--I--LRDIDARGAHAMRLRERLETMRGSPYFARLDFapdgaS-AAEAHYIGRQGLQs-- 118 
WP_000065177   35 ----------------------E--DFKEQILESMRESNRQNLRIGVQEPYFGRLDFqedgkE-EVMPIYIGKVGVSDMd 89  
WP_087455565   39 ----------------------D--DLTEQALDNIRESRRQNLSIAGVEPYFGRLDFqeagvE-TPQPLYIGKVGVEDEd 93  
WP_096551757   36 -------------tllkeKA--S--LTGDEIAYRRGIKDQELLKKAKEEPYFGRFDIvs-eeEgE-ETFYIGKQGVRDK- 95  
WP_123043829   30 ----------------------Q--DFVEQLLEAKREETRQRLKVLGTEPYFGRLDFqekgrQ-APAPLYIGKRGMDRRd 84  
6WVK_H        129 EE-HFLIYDWRAPISSLYYNYSPGkaeye--------vpgetIEGEMVLKRQFMIKNGTLKAMF---------------- 183 
WP_012199658  111 AT-EIEVIDWRAPISSVYYESEVGecnyrv-------pegelREIKLNLKRTYEVEKDKLLDFY---------------- 166 
WP_012742026  116 AS-EPVVIDWRAPIASVYYESSLGpckytv-------ssegtFEIDLNRKRTYEIAEDKLIDFF---------------- 171 
WP_013372623   94 TSaYPLVIDWRAPIASLFYSFTGGeetasy------eapegtVEGLVYLKRNVVIRKRILERVA---------------- 151 
WP_014081292  122 GS-EPVVLDWRAPIASVYYESSMGpctytv-------ssegtYEMDLVHKRTYEIEQDVLKDFF---------------- 177 
WP_014911307  119 AE-GTAVVDWRTPLGGMFYEREPGrasye--------apsgtIGGTIERKRQFKVENGRLRFVL---------------- 173 
WP_000065177   90 TM-KPIIIDWRAPVASMFYSFTGGeelafy------qspdglVEGDVYLKRNISIRKRELERVV---------------- 146 
WP_087455565   94 TG-KLLVIDWRAPVASMFYSFTGGdekaay------dspeglIEGLIYLKRNLVIRKQILQRVV---------------- 150 
WP_096551757   96 DE-NLIVVDWRMPIASVYYNFTPGqptqvytvedektrrktkITVDVVRKREFTIKNKKIKKIVqqvaepnsslnvtfte 174 
WP_123043829   85 TG-EPYIIDWRAPVASLFYSFTGGdesviy------eapegsVEGEVHRKRNLSIRDRILQRVV---------------- 141 
6WVK_H        184 --NTDMT------IGDEMLQEVLSHH-SDTQMKNIVSTIQKEQNQIIRNEKSKILIVQGAAGSGKTSAALQRVAYLLYRH 254 
WP_012199658  167 --DSEVV------ANDELLTKYLAKN-KEAVLGEIIATIQKEQNDIIRQSPFHNVVVQGVAGSGKTTVAMHRISYILYNY 237 
WP_012742026  172 --DSDVV------ANDELLTKYLAKN-KKAVLGEIIATIQKEQNLIIRRSPKTNIIVQGVAGSGKTTVAMHRISYILYNY 242 
WP_013372623  152 --DTYNResdepaVSDEFLVYRLGEN-KDNRLRDIVSTIQAEQDQIIRAAKNTALVIQGVAGSGKTTVALHRLAFLLYQY 228 
WP_014081292  178 --DSDVV------ANDELLTKYLAKN-KKAVLGEIIATIQKEQNVIIRRSPRTNVIIQGVAGSGKTTVAMHRISYILYNY 248 
WP_014911307  174 --DTAEA------IRDEILLEEIGRT-SSAHMRSIIATIQREQNAIIRNESDGTLIIQGVAGSGKTSIALHRIAYLLFRR 244 
WP_000065177  147 --DTYVKgnedvsHADDFLLYRLGEN-KDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEY 223 
WP_087455565  151 --DAYVKggdnldVADEFLLYRLGEN-KDNRLRDIVSTIQAEQDKIIRSAKNTALVIQGVAGSGKTTVALHRLAYLLYQY 227 
WP_096551757  175 tgEE-LT------ITDDFLREILEQSeTTGYLKEIIATIQKEQDKAIRQPIDRNVIIQGVAGSGKSSIALHRLSFLLFN- 246 
WP_123043829  142 --ESYVRggenlgLSDEFLLYRLGEK-KDNRLRDIVSTIQSEQDRIIRAPRRLAIIIQGAAGSGKTTVALHRLAFLLYQY 218 
6WVK_H        255 RGVIDAGQIVLFSPNFLFNSYVSSVLPELGEENMEQATFQEYIEhr-----lGrkfkC---ESPFDqleycltetkggdf 326 
WP_012199658  238 QEKFRPKEFFIIGSNRILLDYITSILPDLDVYGINQMTLEQFCLflld---------ediiTDKYKi------------- 295 
WP_012742026  243 ADDFRPEDFYIIGSNRILLNYITSVLPELDVYGIKQMTMEQLFTrlly----------edwDDKKYsihe---------- 302 
WP_013372623  229 KDQVSADKMVIFAPNHMFLDYISDVLPELGVGNIQQSTFADWALgllg-ldlP----L---ADPTEt------------- 287 
WP_014081292  249 KDDFRPEDFYIVGSNRILLNYITSVLPELDVYGIRQLTMEQLFVrlly----------edwDDARYsyhs---------- 308 
WP_014911307  245 RGRLKAENIAIISPNGLFAEYVSDVLPELGEEAVVALDLAAVARgrlerhrlG----F---TDPIDp------------- 304 
WP_000065177  224 REQLEAERMIVFAPNSLFLDYISSVLPELGVGNISQTTFLDWALrtld-dsvK----L---KQTEEk------------- 282 
WP_087455565  228 RENIRAERMIIFAPNSMFLDYISGVLPELGVGGIQQTTFTDWALdlle-qevQ----L---SDPSEr------------- 286 
WP_096551757  247 NKHIKPENVLILGPSKLFISSFKGLLPELNLEGIQQMTFQQLALtile-tilK----DkvdLSYNWy------------- 308 
WP_123043829  219 QDQVKAERMIIFAPNAMFLDYISGVLPELGVGSVRQTTFADWALdklg-esvR----L---AEAGGe------------- 277 
6WVK_H        327 pTR-------------LAGITWKAGLSFQQFINEYVTRLsSEg-mIF-KNIIFrG-QK-LITKEQIQSYFYSLDQNHSIP 389 
WP_012199658  296 iSHiqkd-----kkeyKKFAERKGSLSYLKELDAYLNQR-EIemiPR-KTVVY-E-DEvLFSEEAFDDFL-KNNQMWSTQ 365 
WP_012742026  303 ------------vsknDSRNSIKGSKEWFEALEKFCLDY-EEkciPR-DEVYMeKtGNlLVGKVLIDTYL-HDNPLLSMQ 367 
WP_013372623  288 lSYwfesgglrtesmdEAPGRFKGSVHFMKLLQDFVERL-EPisvPE-GDFSP-W-DGaVLPRTEILNWFNEEYKPYPLA 363 
WP_014081292  309 ------------merdDPKNSVKCDTEWFLDLKTYCEEY-EKesvPA-EDVYLeKtGKlLIGADEIRRYL-KEHPADSME 373 
WP_014911307  305 vEPlgpg-----gaaaRERARAKSTLAFHHWLERALDEA-IQdcfVP-RELRL-G-NLr-IDAEELRAHF-DRLSALGVA 373 
WP_000065177  283 lKEafsin---rdekkIMLGKLKGTLEFKTFIEERMIQF-ENelvPT-KDFEA-W-DRaIIPVEDIKKWMQVEYKHYPLQ 355 
WP_087455565  287 lDTwfaigpkrpvldeHAPGRYKGSMHFYRYVEAYLQAF-EEgfvPE-VAFEA-W-EGkTLAAATVKEWFYTEYQHYPLA 362 
WP_096551757  309 fENvlftr---dsddeRKRIEFKGSESLALLLDIFVEEM-KDqyeNriQPITI-F-DEr-LDKETLKKIF-DGYNYLPFG 380 
WP_123043829  278 gEIwfstagrrpaiddLTPGRFKGSLRYRDWIEAELNRY-EDaylKD-ENFEA-W-DRrMLPAGTIREWFDVEYRHYPLA 353 
6WVK_H        390 NRMEQTAKWLLSELNKLEKKERRKdwvvheaelldkedyldvykklqerkrfsestfndyqrEQqlLAAIIVK--KafKP 467 
WP_012199658  366 AKITMLNERALNKIRNYF--------------------------------------------TG--RDYEYEKeeK--KV 397 
WP_012742026  368 SKILMLNEIIYSKYENEV--------------------------------------------LG--KEVKFPAkeR--RV 399 
WP_013372623  364 KRKERVLARVHRWIEMEL-KKSPS--------------------------------------AA--ALKERKKkaG--SR 400 
WP_014081292  374 SKMLMLGEIVHSRYENEI--------------------------------------------LG--RDITFPAeeK--KR 405 
WP_014911307  374 ERLRVMAEHLCQRARSES-------------------------------------------------PLFASApkV--GE 402 
WP_000065177  356 KRRERLVGRMKRWIEIEL-KKFGE--------------------------------------TN--EKKLLKKeaT--KR 392 
WP_087455565  363 KRRERVVGRIKRWLEMEL-EKVWD--------------------------------------SI--KRKDLKKkaN--AR 399 
WP_096551757  381 KKVERFLQHIENHFKNVMENKIdeitkqydfivhtflknggltqneynqlteqiksiyqykvRQ--LQKQF----K--ET 452 
WP_123043829  354 KRRERLIGRINRWLEMQL-KEIGD--------------------------------------PK--IRKERAKtgK--QR 390 
6WVK_H        468 LKQAV-RLLA----FLDVTQLYLQLFS------GW-GGKFQ-HEKMDAIGELTrsaftDNKLLYEDAAPFLYMQDLIEGR 534 
WP_012199658  398 AIKQFnNYYGpkkwKYALITLYQEFLQwm--ltKT-----EgEEQLGI--NDCilslsKKEVDVYDLAALLYIKRRMVLT 468 
WP_012742026  400 LDKKYkTYFGkddwKGSVYDFYRDFLLsq----------kE---------KEYdidipKDSFDVYDLAALAYIYKRIKET 460 
WP_013372623  401 EKAYAkK-WP----QYDALTLYKQLFQaakglpAEaAAEMK-ASLPASIFKATqsdlrSQIIREEDLTALVYLHVLIHEV 474 
WP_014081292  406 LDRKYtMYFGkgkwEGSVYAFYQDFLAaq----------aA---------RGRevtppGNSFDVYDLAALAYIYKRIKET 466 
WP_014911307  403 VVKRLtAMLT----VKSARALYRGLFRre----------dA-PTVFRAp--------gPGLLEWEDVYPFLFVAGRFGGW 459 
WP_000065177  393 LNAYMkF-WP----KMSALSLYSSIVKske----------ilEVLPEELVKETekscrKKEVYVEDLPALIYIHHRITGI 457 
WP_087455565  400 LRTYLkG-MP----DLTPFGLYKKMFGd-------------aADLPESIVKASvkkfkKKIVDLEDLAPLLLIRNRLHGI 461 
WP_096551757  453 FSLWKeK-MM----LPDPVSIYKQVLTyev-ldAFq-------HEVGSDiPHLfknyiLEEITYFDLPPLLYIYLLLYD- 518 
WP_123043829  391 LKAFEkK-LP----QADPMTFYRSLFEq-----------pE-AFVPADLAARTkallkKGQAMPEDLPALVWIHRRFHGP 453 
6WVK_H        535 KKNTKIKHLFIDEAQDYSPFQMAYMRSIFPAASMTVLGDINQSIYAh--TINGDQRMD-AC--FEDEpAEYVRLKRTYRS 609 
WP_012199658  469 EEMEDARHVVVDEAQDYGAMVFGVLRYVLPRCTFTVMGDVSQNINYdsgMNDWE-ALKqEVf-NKDR-DTFGVLAKSYRN 545 
WP_012742026  461 DPVREASHVVIDEAQDFGMMAYCCLHYCLRNCTYTIMGDTSQNIHFeygLNDWE-DLK-KLilTGTY-DAFGLLRKSYRN 537 
WP_013372623  475 ESSQRFDHVVIDEAQDFSPFHIALLDLFVKGHSFTILGDLSQGIHEyrgVHAWE-EMS-SLf-APEQ-TGYFALTRSYRS 550 
WP_014081292  467 DPVREASHVVIDEAQDFGMMAYRCMDACLSDCTYTIMGDTSQNIHFqygLNDWD-ELR-RLilTGDY-DAFGLLRKSYRN 543 
WP_014911307  460 ETDQDVLHLVIDEMQDHSPTQYAVLRRIF-RHDMTILGDVAQALGNte-dYTLE-RLG-GLf---QG-ARVMELTRGYRS 531 
WP_000065177  458 EIGQKFHHVVIDEAQDFSPFQVYVLKEITLGNSFTILGDLSQAIYDyqgIEDWN-AFK-EVf-QE---TGYYELTRSYRS 531 
WP_087455565  462 DSANMFDHVVIDEAQDFAPFQVALLKEQTRGNSFSILGDLSQGIHAyqgVHAWQ-EFL-ELf-TEEE-QAYFQLDRSYRS 537 
WP_096551757  519 -RPIQYAHIVVDEAQDFSYLHFAVLNKI--TKTMTILGDKDQSIYLrygQYDWDELMD-SLf-ARDR-DTILTLETSYRS 592 
WP_123043829  454 --DETFDHVVLDEAQDVPPFQIALLHTMMVEPSFTILGDLAQGIHAyrgVQRWE-ELS-SVf-PEDR-RAYHELRMSYRS 527 
6WVK_H        610 TRQIVEFTKAML-----QDGADIEPFNRSGEMPLVVKTeGHESlCQKLAQEIGRLKKKGH----------ETIAVICKTA 674 
WP_012199658  546 TIEISNYATSILsh-csFPTYQVEPIIRHGAMVAKHQVaKESEmVSNAVRIIKSWQETGY----------DTIAVICKDS 614 
WP_012742026  538 TVEISEFATEILrh-gdFAIYPVEPIIRHGNAVRIEEYaNVRSlISASVDTIKGWQSEGY----------ETIAVVCRDE 606 
WP_013372623  551 TLEIIEFANTILeq-gvRGGITAVPVFRSGDPVRTVSYdSSVr-EESLLTALKELSSKEY----------RTVSVLTRTL 618 
WP_014081292  544 TVEISTYANEILrh-gdFSIYPVEPIIRHGAGVCVEPVqGERAlLNRAAETIQGWQRKGY----------ETIAVICRDE 612 
WP_014911307  532 TVEIARFASAI-------RGTAVTTIDRHGDRPRVLGFdTPVEeVDRIAAEIDRFRSTGApdgsgdegdpGRLAIVTRSR 604 
WP_000065177  532 TKEIIEFANEIIkn-aeIPVGLATPVFRSGEDVKVIHAeNQ---FTEIVKTVKHLQNADV----------KTIAVIGRTE 597 
WP_087455565  538 TTEIINFANVVLer-sgEALTLAVPVFRSGEKVRVAQVaEQDr-LQTIVDAVKRLQSGTH----------TTVAVVARTE 605 
WP_096551757  593 TKQIIEVANTVLanqygTSHQPITPINRNGAAVQFVEVkSGQDlLDNIVSTIKEWK-KRY----------KRIAIIHKDE 661 
WP_123043829  528 TLEIIEFSNRILpf-tgTSLPPAQPVFRSGDPVEVAEVrSSEEkIARISAYIADNRTRGM----------QTIAVIARTD 596 
6WVK_H        675 HqCIQAHAhms--eyTDVrl-ihKENQP-FQKGVCVIPVYLAKGIEFDAVLVYDASEEH-YHTEHDRRLLYTACTRAMHM 749 
WP_012199658  615 EsTEKVSKlls--kqMEVme-gsLENAV-FSKGVMVLPIQLTKGLEFDTVLLWNPNQESyEKSDANAKLLYVAATRALHE 690 
WP_012742026  607 AeALKVSAelk--khIEIae-ddIETAQ-FGAGVMVLPVAYTKGLEFDAVLLFDPSERKyPADDSHVKLLYVAATRALHE 682 
WP_013372623  619 KeAVELHEvft-sagLDVhl-idGGKKQ-YEGGLSVLPVYLSKGLEFDAVIVADADQDHyGERTWDAKLLYVGCTRALHE 695 
WP_014081292  613 EeAERVAArla--edVPVkngakGETEE-FGDGVMVLPVSYTKGLEFDTVLLFDPSEKKyPSDNGHVKLLYVAATRALHE 689 
WP_014911307  605 AgARELHGels-erlEGVvl-atADSRGvLGNDVTVLPVGLAKGLEFDEVIVARASEREy-GAEAGRSLLYIACTRALHR 681 
WP_000065177  598 DeCRDIYVelt-nagLTVnv-ieANQSK-YEGGISVVPVYLAKGLEFDAVLLIDVDEEHyKDTKHDAKLLYVGCTRSLHD 674 
WP_087455565  606 EeSRDLHAgll-qagLEAtl-ihSKQRE-YKGGLSVLPVYLTKGLEFDAVLITDVDEEHyAHSPQDAKLLYVGCTRALHE 682 
WP_096551757  662 QkAMRLAQylkqeykSdVvy-isPDQEV-AKQSISVLTSYYSKGMEFDAVILVNVNEESfPKDDLHARLLYVLVTRAQQE 739 
WP_123043829  597 DnCRELAAele-kagVEArl-isEGQTR-YGGGVSIVPVYLAKGLEFDAVLLADADAEHyADDPQDAKLLYVACTRALHR 673 
6WVK_H        750 LAVFYTGEASPFVT 763 
WP_012199658  691 LTMVYQNKLSELL- 703 
WP_012742026  683 LAVFHRGRlttlia 696 
WP_013372623  696 LWLLHDGPLPSYVQ 709 
WP_014081292  690 LTILHRGElsgila 703 
WP_014911307  682 LTLTHSGRPSPHLP 695 
WP_000065177  675 LWIFHSGEASPLIK 688 
WP_087455565  683 LWLLYAGTPSPLIA 696 
WP_096551757  740 LRVFYQNTPSPLLE 753 
WP_123043829  674 LTLLYQGKSSPLLT 687 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap