Conserved Protein Domain Family
CofD

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COG0391: CofD 
Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family [Carbohydrate transport and metabolism, Coenzyme transport and metabolism]
Statistics
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PSSM-Id: 440160
Aligned: 439 rows
Threshold Bit Score: 109.839
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015405383  71 EpvSHLNVVVFGGGTGLSTIIggdsraeswvndpfQGL--KAL--FPKTRSIVCITDDGGSTGELlkdlplIALgDIRHV 146
BAN03175       1 MstSTDRIAVISGGVGAARFL--------------RAV--ISAvdPERIDAVVNTGDDTVLHGLS------ISP-DLDTV 57 
WP_011322734   1 ------MVTFLAGGTGTPKLR--------------YGA--ETVfdTADTPVVCNTGDDVELGGLV------VCP-DVDTV 51 
WP_014051263   1 ------MVTFLAGGTGTPKLL--------------SGE--SPVfaRDAVTVVGNTGDDVELGGLL------VSP-DLDTV 51 
WP_014556691   1 ------MVTFLAGGTGTPKLL--------------QGA--PAVfdPAATTVIANTGDDVELAGHL------VCP-DVDTV 51 
WP_089672861   1 ------MITFLAGGTGTPKLL--------------AGA--TAQfdPDGLTVVANTGDDIELGGLL------VSP-DVDTV 51 
WP_103425922   1 ------MVTFLAGGTGTPKLL--------------DGLgpDGPvaPSDVTVVGNTGDDVELGGHL------VCP-DVDTV 53 
WP_119815767   1 ------MVTFLAGGTGTPKLL--------------DGA--VRLlePSNVSVVGNTGDDIELGGLL------VCP-DIDTV 51 
WP_114593331   1 -----MNVVSLAGGIGAARFL--------------RGL--VRAvdPASLTVVANTGDDLAIHGLH------VSP-DLDTI 52 
WP_121919355   1 ------MVTFLAGGTGTPKLL--------------DGV--DAAfdPAEVTVVANTGDDVELGGLL------VCP-DLDTV 51 
WP_015405383 147 LLSSI---Q--------LARlqeyyslteieaaqcvkILARVFNH-------------------------RF--SEKpts 188
BAN03175      58 TYTLAnaiDpvrgwglvDETwta------------maALERYEEV-------------------------RPdgSSAapr 100
WP_011322734  52 LFAAAdrlDretwwgidGDTtet------------heELRALADAadldtgprylpdkkqtagrdiarwrRF--S-Gvae 116
WP_014051263  52 LFDGGgvlDretwwgiaGDShet------------ddELFALADAagletgprylddaaqtsgrdivrwrRF--S-Gvge 116
WP_014556691  52 LFSEGgvlNtdrwwgieDDTtet------------htEIAKLANKagladdprylsadeqtsgreisrwrRF--S-Gvae 116
WP_089672861  52 LFHEGdvlDtdrwwgieDDThet------------naELHRLAEEadldtgpqylppreqtagrpiarwrRF--S-Giae 116
WP_103425922  54 LFHGGdvlDrdrwwgiaGDTtet------------hdELHRLADAaglgdgprylpddaqvagreiarwrRF--S-Gvae 118
WP_119815767  52 LFRGGgvlDretwwgiaDDTttt------------htELHRLAEAaglepgprylpeelqtagreiarwrRF--S-Gvae 116
WP_114593331  53 TYTLGggvHpeqgwgraEETftv------------aaELKGRY---------------------------------Gqpd 87 
WP_121919355  52 LFAGGsilDretwwgidGDTtat------------hdELGRLAEAadlsggprylppdrqtagrriarwrRF--S-Gvae 116
WP_015405383 189 ntkllhdcgligdadtvlpaaifgsleriihklfvDprlqvtlNRPHCLGNLILVSsiyeqipahftnaalisepdlirQ 268
BAN03175     101 wf----------------------------glgdqD-------LATHFYRTARLAE-----------------------G 122
WP_011322734 117 fm----------------------------eigdtD-------RAVHITRTSLLDE-----------------------G 138
WP_014051263 117 fm----------------------------tigdrD-------RAVHITRTSLLDE-----------------------G 138
WP_014556691 117 fm----------------------------eigdrD-------RAVHLLRTSLLDE-----------------------G 138
WP_089672861 117 fm----------------------------tigdrD-------RAVHITRTSLLDE-----------------------G 138
WP_103425922 119 fm----------------------------eigdrD-------RAVHLTRTSLLDE-----------------------G 140
WP_119815767 117 fm----------------------------eigdrD-------RAVHLTRTSLLDE-----------------------G 138
WP_114593331  88 wf----------------------------tlgdrD-------IATHLVRARVIGE-----------------------G 109
WP_121919355 117 fm----------------------------eigdrD-------RAVHVTRTSLLDE-----------------------G 138
WP_015405383 269 -NIHRGIASLCTILGAdEHAVMPCTYVPAELSLRYTN--G-V-----------------------QVTGEHKSSEARRgy 321
BAN03175     123 aTLTEVTEEIRRAWTV-PIRLIPMSDERCSTMVTLADdgT-E-----------------------VSFQDYFVRLHHSv- 176
WP_011322734 139 kRLTEATATLADALGV-DHPVLPMSDDPVATLIDTDE--G-L-----------------------VHFQEFWVHRRAEp- 190
WP_014051263 139 hTLTEATRTLADAFDL-EIDLLPMSDDPVATIIHTPD--G-A-----------------------MHFQEYWVANRAAp- 190
WP_014556691 139 kRLTEVIEILADAFEV-DINLIPMSDDPVSTLIHTEV--G-AesettekqttenesetaetaaeiMHFQEYWVHNRAEp- 213
WP_089672861 139 kTPTEATRILADAFDV-DLTLLPMTDDPVATIIATEE--G-P-----------------------IHFQEYWLG-PADh- 189
WP_103425922 141 rSLTEVTRTLAEAFGL-DVDLVPMSDDPVATIVHTVE--G-E-----------------------MHFQEYWVSRRAEp- 192
WP_119815767 139 yRLTEVTRLLAEAFDL-EVDLVPMSDDPVASIVHTEA--G-E-----------------------LHFQEYWVDRRGEp- 190
WP_114593331 110 gTLTDATRTIASAWDL-PFALLPMTDATVATRVRTSD--GrE-----------------------LHFQEWWVGERAAs- 162
WP_121919355 139 rTLTEATRTLADAFDL-DVTLLPMSDDPVATIVHTDE--G-A-----------------------MHFQEYWVARRADp- 190
WP_015405383 322 PVDTVLINfCAEPEVSDDVLGLIHNADIMIMAPGSLYSSLVPIFQVPKIAEAVKNNrKALKILVSNLWV---QAGETDis 398
BAN03175     177 PVSSVRFDg--EADLGPSAHDAIASASVVMIAPSNPLVSIGPIRSLPGAEDLLASR-RDDCVAISPIVGgaaLKGPADrm 253
WP_011322734 191 TINGVEFRgADAAEPTPEVREALA--DPVVIGPSNPITSIGPMVALDGIRKALAET---PVVAVSPFVEdrvFSGPADdl 265
WP_014051263 191 RVEDVEFRgASRAQPTAAVHAALS--EPVVVGPSNPVTSVGPIRALPAVDRALHQT---PVVAVSPFLEdepFSGPVAel 265
WP_014556691 214 PVLDVEFRgVDAATPTQSVKTALT--EPVVIGPSNPVTSIGPMIAMDKFESALEDT---SVVAISPFINdrvFSGPAAsl 288
WP_089672861 190 DVQGVEFRgAEEAEPTTHVLDALD--APVVIGPSNPVTSIGPMLAVPGIREALERT---PVVAVSPFIEdevFSGPAAel 264
WP_103425922 193 QVEEVEFRgADDAEPTAEVLDALT--DPVVVGPSNPVTSIGPVLALSGVEAALAET---PVVVVSPFVGrevFSGPAAql 267
WP_119815767 191 DVEDVEFRgATDASPTQEVRAALT--KPVVIGPSNPVTSVGPILALSGAREALHAT---PVVVVSPFVErevFSGPAAdl 265
WP_114593331 163 PIDRVWLEgGEDARATDAVVAAIEGADLVVLCPSNPVVSIGTILDIAPVRELLR---DKPVVGVSPIVGgrvVRGMADkl 239
WP_121919355 191 AVEDVEFRgSHAADPTPAVRDALD--APVVIGPSNPVTSVGPIRALPGVDDALTET---PVVAVSPFVEdevFSGPAAdl 265
WP_015405383 399 iynperKFLLSDLLKAYERNIpggtgGLFDKVLCLsLKdvpatviqnyavegkipiylDR---DEVREQGIIPLECG-IY 474
BAN03175     254 ----ltELGHEPTVVGVARLYa----PIASVLVID-PA--------------------DAalaDAVEAEGLRCVVQPsIM 304
WP_011322734 266 ----maADGYAPSTAGVAEAY-----PFADAFVVD-EA--------------------DEtplER------PTVRTDtEL 309
WP_014051263 266 ----maGVDREPSTAGVANTY-----AFADAFVLD-SQ--------------------DEttlDR------PVVRTDtNI 309
WP_014556691 289 ----mkAVGFEPSTAGVAEAY-----PFADAFILD-TA--------------------DQttlDR------PVVRTDiEL 332
WP_089672861 265 ----mdGTGREPSTRGVADAY-----PFVDAFVLD-SE--------------------DGtdlDR------PVVRTDtKI 308
WP_103425922 268 ----meGVGLDPSTAGVADAY-----PFADAFVLD-TA--------------------DGtelGR------PVVRTDtRI 311
WP_119815767 266 ----mnAVGYEPSTAGVAEAY-----PFADAFVID-ND--------------------DGtdlDR------PTVHTDvTI 309
WP_114593331 240 ----lpAVGAEVSAAGVAGLYa----DFLDGWVID-TA--------------------DAasaDAIRATGVDVAVTDtMM 290
WP_121919355 266 ----mrGVGLDPSTAGVADAY-----PFVDAFVLD-DA--------------------DGtdlDR------PVVRTDtRI 309
WP_015405383 475 -SRTalrddgvirhDPKQFALVVRT 498
BAN03175     305 sEPQ----------VAYDLAMAALH 319
WP_011322734 310 gSPA----------DGERVCRAVRE 324
WP_014051263 310 dEPE----------DAERVARACGL 324
WP_014556691 333 dTDT----------DAKRVLQAVQT 347
WP_089672861 309 dDEA----------DSRRVMEAVIE 323
WP_103425922 312 dGPG----------DAGRVLDAVWE 326
WP_119815767 310 dDAD----------DAERVMRAVAT 324
WP_114593331 291 vDVD----------VSTRLAETAVG 305
WP_121919355 310 dDAA----------DARRVVDAVAA 324
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