6Z92


Conserved Protein Domain Family
2-thiour_desulf

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pfam04463: 2-thiour_desulf 
2-thiouracil desulfurase
This family of proteins, predominantly found in Bacteria, are involved in the desulfuration of 2-thiouracil into uracil in the 2-thiouridine degradation pathway. It has been demonstrated that these proteins contain a Fe-S cluster required for their activity.
Statistics
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PSSM-Id: 461320
Aligned: 338 rows
Threshold Bit Score: 52.8398
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6Z92_A                      5 IIVSACLLGQPVRYDGQSKGI--VSNWLDALGaegRALAFCPEVAGGLPTPRPPAERqg--------ehVVTESGl--DV 72 
WP_015046466               17 IGISACLMGHEVRFNAGHKRHgfCADQLVNIA---NLVPMCPEVAIGLPTPRPAIRQvhrdd---viavEWSKPKagdEV 90  Si...
zhongguo:B5T_04166         23 vaASACLLGQPVRYDGGHKYHstVANTLAARV---TLVPLCPETAIGLPVPRPPIQVvlvge---aqrvRGLAAPn-eDF 95 
Q0VLV8                     23 IGVSACLTGQKVRYDGDHKHNaiVIHQLAPWL---RFRETCPEVAIGLPVPRPPIQVvqleg---rlrvRGVDQPq-qDV 95  Al...
WP_012012576                3 lGVSSCLLGNMCRYDGHGAKDefVFNSLKEYF---ELLPYCPENSI-WSAPRDAIRQvlind---eikiFTSTKEp-kDV 74  Al...
jgi:Desaf_0362              8 IVVSRCLMGEAVRYDGSHKHApeIIAALTSRF---ALIPVCPEVEAGMPTPRETMDFqgdpr---rpavIGKISRr--DF 79 
CBW27402                    9 IAISSCLLGNLVRYDKNHCKDnwIVNELSKYV---ELVPICPEMRMGLGVPREEIHLyhrpgekdkvrlKKKFDGq--DL 83 
BAF70646                    7 aAVSACLLGHNCRYDGSNKKDesLQTVLKGCD---EVIAFCPEDA-ILGTPRETIDIvne-------raIGNESGt--DY 73 
WP_013554527                6 VAISACLLGERCRYDGTDNRDpkLLGKLEGC----ELIPFCPEDH-AFGTPRPTMDLvetee---gvkaISNLTGa--DL 75  Ni...
Academia_Sinica:M5M_13175   7 lWVSACLLGKPVRYDGGHKHQagLENWLNSWA---HIVPLCPEVFAGLGTPRPPIQRqqtaq---gdrlVLAETGe--PT 78 
6Z92_A                     73 TAEFDRGAELALG---LCLAQ-GIRFALLKEGSPSCGSGRI---Y----------NGRfegVS-MaGEGKTTALLRRHGI 134
WP_015046466               91 VDFAPALAAKASEf--LAAHD-DLDGYIFMNDSPSCGSVNVk-tYr--------tNGY---QAtRkGVGVYAAGIMAAAP 155 Si...
zhongguo:B5T_04166         96 SDALADYADGLAL---------ALDGVVLKSRSPSCGFGTTp-lHdesgr------------elgftSGAFAARLHARLP 153
Q0VLV8                     96 TDALENVAATLQQ---------PLSGFVLKARSPSCGYLNTp-vHnpqgq------------qigiaSGAFANKLHQHFP 153 Al...
WP_012012576               75 TLMLEEACEKMAL---KATQD-DLCGFVLKSASPSCGMERVk-vYk--------pENA---PSvKnGVGIFAKKLKEKLP 138 Al...
jgi:Desaf_0362             80 APLLHDWSRAKLAalaGLSEL-AVCGFFLKFNSPSCAAVTRkpvFdlygr------------prgetFGIFAGLAMRAFP 146
CBW27402                   84 TRLAEETYAMMNE---DIREV-EYDGMILTKKSPSCGIDRVktiEegrpd------------kvtwsTGLFAKNILENFP 147
BAF70646                   74 TEWIEKYALNLCQ-----KHP-DIDMFVVKSKSPSCALASAk-hYdkdkn------------likngEGIFTKTVQKIKP 134
WP_013554527               76 SPPVEQYARNFFD------THpDIDLFIGKDRSPSCGVCSAr-lYdrdkklidnrA-----------SGLMAAEAKRRGI 137 Ni...
Academia_Sinica:M5M_13175  79 AAALPDACQTLVR-----QQP-VPAGAILKARSPSCGAGNSp-lFdphnr------------lighgDGVFVQALKARFE 139
6Z92_A                    135 QVFSEDQ 141
WP_015046466              156 LMPVEDA 162 Simiduia agarivorans
zhongguo:B5T_04166        154 FLPLcnd 160
Q0VLV8                    154 RIALAne 160 Alcanivorax borkumensis SK2
WP_012012576              139 NFPIEEE 145 Aliarcobacter butzleri
jgi:Desaf_0362            147 Gaafgde 153
CBW27402                  148 SLPIIDs 154
BAF70646                  135 DVKIfer 141
WP_013554527              138 DAWDAEd 144 Nitratifractor salsuginis
Academia_Sinica:M5M_13175 140 GLAIvde 146
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