4J7C


Conserved Protein Domain Family
2a38

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TIGR00933: 2a38 
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potassium uptake protein, TrkH family
The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]
Statistics
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PSSM-Id: 273349
Aligned: 17 rows
Threshold Bit Score: 306.12
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4J7C_I        54 LLMLP--ISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGKKIGLKER 131 Bacillus subtil...
P43440        32 LLTLPffSRSGESTHFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMTLIEIGGLGFMMIPILFFAIAKKKISFSMR 111 Enterococcus hi...
P21166        83 VGALPfiFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGV---GGMQ 159 Escherichia coli
P44843        83 LATLPllLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGI---GGTQ 159 Haemophilus inf...
P23849        86 ISAFPlwIDSELNLTFIDALFEGVSGITTTGATVIDDVSSLPRAYLYYRSQLNFIGGLGVIVLAVAVLPLLGI---GGAK 162 Escherichia col...
BAA31229      84 FAALPfvFINH--ISFTDAYFETMSGITTTGSTVLSGLDNMAPSILLWRSILQWLGGIGFIVMAVAVLPMLNV---GGMK 158 Vibrio alginoly...
CAB49294      95 VSVVPfmSIAK--MSFIDSLFETMSAWTGTGLTMMSHLESYPKVILFWRAWMQWLGGIGIVLVALTILIRPGV---AAAR 169 Pyrococcus abys...
WP_002557310  25 LLMLPisWEGDGKLAYIDALFTAVSAVSITGLTTVKM-EGFSTFGFILIMLLIQLGGLGFISITTFYLLIPKKKMNLTDA 103 Lyme disease sp...
WP_010888302  38 llHLPgvQRPGAALNSIDLLFTATSAICITGLTVADTGEAFTRFGQVLIILLVQIGGLGILTFGTVFAFMTGRRVNFTER 117 Deinococcus rad...
WP_010878342  84 FGSIPyiIFG---ISPVDAFFESMSGFTTTGASVL-TPEELPKSLLLWRSLTQWIGGMGIIVLFLAIFPNVAKR---STV 156 Archaeoglobus f...
4J7C_I       132 MLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYgwS-SGLFASLFHAISAFNNAGFSLWPDNLMSYVG 210 Bacillus subtil...
P43440       112 IVLKEALNLEEMSGVIKLMIYILKFAVVIQVIGAVALSVVFIPEFg-WaKGIWFSIFHAVSSFCNAGFDLLGDSLLADQT 190 Enterococcus hi...
P21166       160 LYRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAG----MDAFDAIGHSFATIAIGGFSTHDA-SIGYFD 234 Escherichia coli
P44843       160 LYRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSG----MNLFDAIGHSFSTISNGGFSTHDA-SIGYFN 234 Haemophilus inf...
P23849       163 LYQSEMPGPFKDDKLTPRLADTSRTLWITYSLLGIACIVCYRLAG----MPLFDAICHGISTVSLGGFSTHSE-SIGYFN 237 Escherichia col...
BAA31229     159 LFQTESSD-WSD-KSSPRAKTVAKNIVAVYLMLTGLCIVGYLVTG----MNLFEAINHAFTTLSTGGYSTSDG-SMNHFS 231 Vibrio alginoly...
CAB49294     170 LYRAEARS----ERILPNFVNTAKIIVQIYTLLTLVGAYLYYING----MSLFDAFIHSMTGLGTGGMSSHDL-SIGYFH 240 Pyrococcus abys...
WP_002557310 104 RIIKQYSLSNIEYNPIRILKSILFITFSIEMIGLILILICFKLRGv-N-ISFLEALFTTISAFCNAGFSMHSESIYAWRD 181 Lyme disease sp...
WP_010888302 118 QHLVAQLNALDVGSVLGLVRTILLYTFVTEALGAALLALRFVPQFgwG-EGLYQAAFHAVSAYNNGGFVVLSGGLAPYAQ 196 Deinococcus rad...
WP_010878342 157 LFQAEYPG-VSLSKLKPRIRDTALSLYKVYLLLTIAEVALLYALG----LSLFDAINHTFTTLSTGGYSTHSE-SIAFFK 230 Archaeoglobus f...
4J7C_I       211 DPTVNLVITFLFITGGIGFTVLFDVM---Kn-rRFKtFSLHTKLMLTGTLMLNAIAMLTVFILEYs-NpgTLGHLHIVDK 285 Bacillus subtil...
P43440       191 NVYLIMVVSALIIAGGLGFIVWRDILsyhR---VKK-ITLHSKVALSVTALLLIGGFILFLITERngL--TLVKGTFTER 264 Enterococcus hi...
P21166       235 SPTINTIIAIFLLISGCNYGLHFSll--sGr--sLkvYWRDPEFRMFIGVQFTLVVICTLVLWFHn-----VYSSALMTI 305 Escherichia coli
P44843       235 QASIYWVTTIFMLIGGVNFSLHISAFlalGkrnIWrnYWKDPEFRFFLTMQIIFIGIVSLSLYGYg-----LVSDINEAV 309 Haemophilus inf...
P23849       238 NYLVELVAGSFSLLSAFNFTLWYIvi--sRk--tIkpLIRDIELRFFLLIALGVIIVTSFQVWHIg-----MY-DLHGSF 307 Escherichia col...
BAA31229     232 NG-AHWVATTFMFLGGLPFLLFIAal--rKr--rIdvLVNDAQVRGFAYLFVFSSLVISAWLVIRd-----GY-TILDAL 300 Vibrio alginoly...
CAB49294     241 SLSIEIITVFLMIMGAVNFTVHYKvf--rDk--sLrnFFKDIQVKTMFYLLAATIPLMTVSLISYg------HFNPIRAL 310 Pyrococcus abys...
WP_002557310 182 VPEAIVVVSILIICGGLGFMVYRDVNntiKn-kKK--LSLHAKIVFSLSFFLIIIGAILFFFTEMh-K--LKAGYSMSTL 255 Lyme disease sp...
WP_010888302 197 DPLVCLTLAGLVILGGLGFLVQLNVVahlRn-rRRSrLLVYSKLTLLTTAVLLTLGTLVLLGLEWn-NpsTLARLSAPGK 274 Deinococcus rad...
WP_010878342 231 DVRVEAVVAFFAFLGGANFALIY--FllsGkp----vIFRNTEFRAYVCFLALASVVIAAVNLDR--------YSIFESL 296 Archaeoglobus f...
4J7C_I       286 LWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLR-GKKETV--IFRRS 362 Bacillus subtil...
P43440       265 LANTFFMSVTPRTAGYYSIDYLQMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGILLIQMHAMFK-GKTRAE--AFGRT 341 Enterococcus hi...
P21166       306 NQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKrLVHPNA--VYSIK 383 Escherichia coli
P44843       310 TKGALQLTSMSMTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHsLIHPNL--VQPIR 387 Haemophilus inf...
P23849       308 IHSFFLASSMLTDNGLATQDYASWPTHTIVFLLLSSFFGGCIGSTCGGIKSLRFLILFKQSKHEINqLSHPRA--LLSVN 385 Escherichia col...
BAA31229     301 RVSMFNIVSVVTTTGFGLEDFTAWGALPTTLFAFLMMAGACSGSTSGGIKIFRFQIAMTLLNKQMMkLIHPSG--VFVQR 378 Vibrio alginoly...
CAB49294     311 RESIFHAVSAITCTGFGIGnLANYPEVDKVFLSLLMVVGGSAGSTAGGIKLIRIALTFESLKWTIQqAILPKGaiIRRKV 390 Pyrococcus abys...
WP_002557310 256 IFNSIFYSISTRTAGFNYLDNSLISGRTQIISLPFMFIGGAPGSTAGGIKITTFFLIVLAVVKNQN--GNGYI--IGSYK 331 Lyme disease sp...
WP_010888302 275 LLAAFFQSMTPRSAGFSTVNIEGLQTASLFTLIGLMYIGAGSGSTGGGIKTSTLAILVGSAWNMVR-GRGELI--LFERR 351 Deinococcus rad...
WP_010878342 297 RYSIFQAVSIMTTTGFTTADFDAWSDSAKLILVVLMFIGGSSGSTGGGIKVIRIYLLIKYAVHQILrAAEPRT--VRAVK 374 Archaeoglobus f...
4J7C_I       363 IKYPIIIKALAVSVTSLFIVFLGIFALTITe----QAPFLQIVFETFSAFGTVGLTMGl-------TPELTTAGKCIIIV 431 Bacillus subtil...
P43440       342 IRQAAVLRALTLFFVTLSLCVVAIMVLSVTetipkTSGIEYIAFEVFSAFGTVGLTMGl-------TPDLTLIGKLVIIS 414 Enterococcus hi...
P21166       384 LGNRALPERILEAVWGFFSAYALVFIVSMLaiiatGVDDFSAFASVVATLNNLGPGLGvva---dnFTSMNPVAKWILIA 460 Escherichia coli
P44843       388 IGKNRLAPRMIESIWAFFIIFILVYWGCVFavilcGMNTFDAMGAVFATLTNAGPGLGfih---esFIGVPESAKLVFSF 464 Haemophilus inf...
P23849       386 VGGKIVTDRVMRSVWSFFFLYTLFTVFFILvlngmGYDFLTSFATVAACINNMGLGFGata---ssFGVLNDIAKCLMCI 462 Escherichia col...
BAA31229     379 YNQRPVNDDIVRSVVAFGLMFFITIIFIAGclsalGLDPITSISGAITAVANVGPGMGsvigptgnFAPLPDTAKWLLSF 458 Vibrio alginoly...
CAB49294     391 GEYEFSEDEIQEVLGFTMTYFAFLLFGTIYmmlrlGAKFADALFESASAIGNVGLSVGi------tSPLLPPDIKVLLIT 464 Pyrococcus abys...
WP_002557310 332 VSIDSIRFALLFFARAIFILSFSFFMLLFFeggsgNWKVIDLGYEVFSAFGTVGLSVGv-------TQDLSFWGKVIIIF 404 Lyme disease sp...
WP_010888302 352 VMNDNLVRAGAITTLYTLLVATAFFAMLATn---pKLGFTHLLFETVSAAATVGLSMn-------tTHKLNDAGLLILTA 421 Deinococcus rad...
WP_010878342 375 FEGRAIKKEILDDIAAFFVLYILIFAVSSIlvslsGYDIVTSISATAATLGNVGPGLGlaga-aenYASFPSLTKILLAV 453 Archaeoglobus f...
4J7C_I       432 IMFIGR 437 Bacillus subtilis subsp. subtilis str. 168
P43440       415 LMYIGR 420 Enterococcus hirae ATCC 9790
P21166       461 NMLFGR 466 Escherichia coli
P44843       465 AMICGR 470 Haemophilus influenzae Rd KW20
P23849       463 AMILGR 468 Escherichia coli K-12
BAA31229     459 GMLMGR 464 Vibrio alginolyticus
CAB49294     465 LMWVGR 470 Pyrococcus abyssi GE5
WP_002557310 405 TMFAGR 410 Lyme disease spirochete
WP_010888302 422 LMYLGR 427 Deinococcus radiodurans
WP_010878342 454 NMWIGR 459 Archaeoglobus fulgidus
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