Conserved Protein Domain Family
Rad9

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pfam04139: Rad9 
Rad9
Rad9 is required for transient cell-cycle arrests and transcriptional induction of DNA repair in response to DNA damage. It contains a Bcl-2 homology domain 3 (BH3).
Statistics
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PSSM-Id: 427739
Aligned: 8 rows
Threshold Bit Score: 302.363
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P26306    13 LARIFTNLSRIDDAVNWEINKNQIEITCLNSSRSGFSMVTLKKAFFDKYifqpdsvllTGLMTPTIRIRTQVKPILSVFr 92  Schizosaccharomyces...
Q5KH95    14 FVRLLQCASKFGDDLHICIGEGLWEMSAVDSSKSAFCLFKLNKDFFYKW---------EKRVSGQIICRILVKSVIAVL- 83  Cryptococcus neofor...
EPY53466  13 LSRIFLNLSRIDDAVNWEINKDQLILTSLNSSRSGFGMVTLTKKFFDKFtfhpdtlflTGFVSPTVRLSTQIKPILSIFr 92 
Q869Q1    13 FSKSLQCISRIGDDLYIEGRQEYIKFTTVNNSKSAFVVFQFSNSFFHSY---------SLEGDEGIQYKAKSKLCFQMFh 83  Dictyostelium disco...
Q5E9X8    32 FGKAIQALSRVSDELWLDPSEKGLALRSVNSCRSAYGCVLFSPVFFQHYqwsasvkmnDTDIILNLNCRLGMKSILPIFr 111 cattle
Q6WBX7    14 FGKAVQTLSRVSDELWLDPSEKGLALRSVNSCHSTYGYVLFSSMFFQHYqwspfatmsDTDLPLNLNCKLAIKSVLPIFr 93  house mouse
Q7QCA1     2 LARAVNCFSKIGNELYFEATPDGLDLKTINSTNTAYAVVQFRRDFFISFqq------gSSDTPDENCCKISVKPILKIFk 75  Anopheles gambiae s...
Q058K5    13 LSRSIICLARVGNELVVQASPTQLALHTLNASRSAYQCITFQSSFFDVY----------TVSGPQAHFSVLLKAVCSVLr 82  thale cress
P26306    93 nkifdfiptvvttnskngygseSASRKDVIVENVQISIs---TGSECR-------------------------------- 137 Schizosaccharomyces...
Q5KH95    84 ----------------------GKSAQMSTVQRIDLRIidpsDELKSRlrrrrrggreangeeqkvfvddgpaypdddea 141 Cryptococcus neofor...
EPY53466  93 nkifessllvtnnpnantgatdSTSKKNVVVENVQIQIt---SGKECR-------------------------------- 137
Q869Q1    84 ----------------------SLS----NIDKCAMKI-----DLEGK-------------------------------- 100 Dictyostelium disco...
Q5E9X8   112 ----------------------CLNSLEKNVEKCKIFT----RSDKCK-------------------------------- 133 cattle
Q6WBX7    94 ----------------------CLNYLERSVEKCTVVA----RADKCR-------------------------------- 115 house mouse
Q7QCA1    76 ----------------------SLA----TIQTCKIWL----EVNQSK-------------------------------- 93  Anopheles gambiae s...
Q058K5    83 -------------------------TPLASIDHMSVQLp---DHDASK-------------------------------- 102 thale cress
P26306   138 -------IIFKFLCKHGVIKTYKISYEQTQTL-HAVFDKSLSHNNFQINSKILKDLTEHFGQRTEELTI----------- 198 Schizosaccharomyces...
Q5KH95   142 vggieakLIMRLVCDHGVIRKHSLHLGTSEFN-RADVDPETTPSGFTISSRTLRDWLDHFSISMPTSGSnasggl---sq 217 Cryptococcus neofor...
EPY53466 138 -------VIFKFYCKHGVIKTYKIAYEQTQML-HAVFDKASCHNNWQINSKILKDLVEHFGQKTEELTI----------- 198
Q869Q1   101 -------ISFYLLCKNGIQKTYSINYELSQLQ-SAVYNKNS-PYKISVKPKQISDCLNYFASNTEEISI----------- 160 Dictyostelium disco...
Q5E9X8   134 -------VVIQFFCRHGIKKIHNVCFQGSRPL-QVIFQKNMCANTLVIQPRVLAEAIVLFTSSQEEVTL----------- 194 cattle
Q6WBX7   116 -------VVIQFFGKHGIKRTHNVYFQDSQPL-KIIFEKSLCANILMIKPRLLTEAIALLTSNQEEVTF----------- 176 house mouse
Q7QCA1    94 -------IIFQFRCKSDVLKTHKIFLLESEHInSLNL-SQTFPSEIVGNHKVFSNILVHLYHSVDEISF----------- 154 Anopheles gambiae s...
Q058K5   103 -------VKWTLQCYSGMKKTYWITCNVEPDIqHLSLDRGRFPSTLVMHPRNLSKLLGNFQSSLQEITIiatdqtsfpsd 175 thale cress
P26306   199 ---QPLQERVLLTSFTEEVVHNrdilkQPTQTTVSIDG-KEFERVALNEG-----------------VSVTLSLREFRAA 257 Schizosaccharomyces...
Q5KH95   218 lgwMFAKDHVKIKSWEGPGNGN-----AGLSTEITIDT-EEFEDYGLIETrylddeatqqggnlgprVDLTLPMKEFKAT 291 Cryptococcus neofor...
EPY53466 199 ---QPVHGRVLLTSFTEEVIHNkdvlkQPTQTTVSIDG-KEFEQVSLNEG-----------------IVITLSLKEFRAA 257
Q869Q1   161 ---NLQRDRLLIKSSTDDKRGL-----KNLFTELVLDR-SDFDEYDFNGDg----------------EEISFNFKDLKTI 215 Dictyostelium disco...
Q5E9X8   195 ---AVTPLKVCIKSSNEESMDLt----DSVYSEMFVGP-DEFDFFQIGID-----------------TEITFCFKELKGV 249 cattle
Q6WBX7   177 ---SVTPGNFCLKSLSGELLDLt----SSVYSEMSFGP-EEFDFFQVGLD-----------------TEITFCFKELKGI 231 house mouse
Q7QCA1   155 ---DLNEEKTIVSNYVDNEQADr----STLRSTLSIDS-SAFQAYQLAGK-----------------ANLIFCYKEFKAI 209 Anopheles gambiae s...
Q058K5   176 aasEIGGKAVEFRSYVDPTKDGd----SLLHTQLWIDPsEEFLQYTHAGDp----------------VDITFSLKELKAF 235 thale cress
P26306   258 VILAEALGSSICAYYGVPGKPILLTFAk----gKNSEIEAQFILATV 300 Schizosaccharomyces pombe 972h-
Q5KH95   292 LVLAEQLSINLNMAFSEAGQPLTITNLe----nELEYIELFCAIATR 334 Cryptococcus neoformans
EPY53466 258 VLLAESLGTSIASYYSVPGKPALFTFNk----gKFMEVEAQFILATV 300
Q869Q1   216 MAYVDVINNPCTWFIERAGLPFHINLK------YSSTYEVDFVLATL 256 Dictyostelium discoideum
Q5E9X8   250 LTFSEAIHAPIAIHFDFPGKPMALSID------D-MLLEANFILATL 289 cattle
Q6WBX7   232 LTFSEVMHAPLAIYFDFPGKPVVLSVE------D-MLLEANFILATL 271 house mouse
Q7QCA1   210 TMFASLNKLNVRMSFSAPGSPLMLEMS------KGEVVHAKFIMGTM 250 Anopheles gambiae str. PEST
Q058K5   236 LAFCEGCEADIHLFFEKAGEPILMAPKfglgdgSSSSFDATLVLATM 282 thale cress
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