1AU1,3WCY


Conserved Protein Domain Family
Interferon

?
pfam00143: Interferon 
Interferon alpha/beta domain
Type I interferons (alpha, beta) belong to the larger helical cytokine superfamily,which includes growth hormones, interleukins, several colony-stimulating factors and several other regulatory molecules.
Statistics
?
PSSM-Id: 459689
Aligned: 96 rows
Threshold Bit Score: 113.827
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1AU1_B         6 LGFLQRSSNFQCQKLL-WQLN---GRLE-YCLKDRMNFDI-PEEIK--QLQQF-QKEDAALTIYEMLQNIFAIFRQDSSS 76  human
XP_019465862  49 LRHQDANFSWKSLQLL-QKAA---PPPPqNCPQQDVTYPF-PETVL--ESK---DKKQAAIITLHILQQLFNILSSPHTP 118
XP_004937150  35 LRPQDATFSHDSLQLL-RDMA---PTLPqLCPQHNASCSF-NDTIL--DTS---NTQQADKTTHDILQHLFKILSSPSTP 104
XP_019217734  26 MDEKFRQHNEETLNLL-DTMVy-nSTNTtEDAEVEVTVAF-PNHLYr-QASKA-SAEDKLAFTVQVLEEVAALFEEDHSS 100
OCA21056      27 LHPKQEYLNTQILKAF-NEMMp-lKETEeICEEHPTDLPN-TESTY--SVSQV-EA--GALAVREVLNETMRFYMKHHES 98 
XP_021588023  69 LEVHLDMSTSENLMLL-TNLS---NSIPvQCFREIHNFEL-PEEIL--SSTQP-EKTNIKYVFYETYTQAINIFSQNTFN 140
6_pfamImport   1 LRKHLLDDNKENLAVLkSQLG---SVFPlQCLNDVISFSSqPEEENiqSIFEL-QKENAAVALHEILQQILCLYIQNHTK 76 
XP_008101700  28 LLTRLREANQANLDVLhRNMG---PSISqQCIDDVFSFS--HREAL--GNINVsEEGNAKAAIQEVLQQTGHIFKQNYTE 100
XP_008101702  28 LCSWLRQANQANLELLnSKMG---STIPqQCIEDVFSFS--PKEDL--RNLDVsEEENAKVAIQEVLQQTGHIFRQNRTE 100
XP_016846565  98 LRSRLRQASQVYLELLnSKMNstiSTIPqQCFEDVFNFS--PKMYL--KNLDVsEEENAKVVIQEVLQQTGHIFRQNYTE 173 green anole
1AU1_B        77 TGWNETIVENLLANVYHQINHLKTVLEEKLEKEDF--TRGKLM----------SSLHLKRYYGRIL-HYLKAKEYSHCAW 143 human
XP_019465862 119 AHWIDHAHHSLLNQMQHYIHHLEQCFVDQGTRSQKqgPRN-------------SHLSINKYFRSIH-NFLQRNNYSACSW 184
XP_004937150 105 AHWNDSQRQSLLNRIHRYTQHLEQCLDSSDTRSRTrwPRN-------------LHLTIKKHFSCLH-TFLQDNDYSACAW 170
XP_019217734 101 ASWEDSTVRNFLNIVNKQAEELHSCIGSHSHKKKN------SQ----------LYFKTEMYFKRLSdDVLKKKGHSVEAW 164
OCA21056      99 MGCKQQAWERFQQLLYYQIHQLEACVSQTEENDLLk-------------------eSISEEFNLLE-TMVLEKDNSACVW 158
XP_021588023 141 SSWDEEQLVQLQSNLYEQVEYLKQCWGKENKEKED--VKADEKkhseagvlplGNLKLRRYFSRIY-NFLKDKTYSRCAW 217
6_pfamImport  77 LPWDENSIGILKVGLKQEIAKLTPCLSEDKQEIRE---------------------DVKKYFERIH-TFLKDGEYNECAW 134
XP_008101700 101 MPWDEDSLRAFHAGLDQQSENLKSCLSASPRiq-------------------lTRLRVKKYFRSLS-NLLKEKEYSRCAW 160
XP_008101702 101 MLWDEDSLRAFHAGLDQQSENLKSCLSASPRSQRIq----------------lTSLRVKRYFRSLN-DFLKEKEYSRCAW 163
XP_016846565 174 MPWDEDSLRVFHAGLDQQSENLKSCLSESPRSQRIq----------------lTRLKVKKYFRSLS-DLLKEKGYSRCAW 236 green anole
1AU1_B       144 TIVRVEILRNFYFINRLTGYL 164 human
XP_019465862 185 DHVRLHARTCFQNVDTLIQQM 205
XP_004937150 171 EHVRLQARAWFLHIHNLTGNT 191
XP_019217734 165 EVIRKETKAHLMRAEQLASSL 185
OCA21056     159 DFIHLETRRNLQQVLQLSSRL 179
XP_021588023 218 EIVRVEITRYFLYLKKFITLH 238
6_pfamImport 135 EVAQIEVSRFFMVMEQLIRTL 155
XP_008101700 161 EIIQIQVKQCFLWIEKIIQEI 181
XP_008101702 164 EIVQIQVKQCFLWIEKLiqmi 184
XP_016846565 237 EIVHIQVKecflwtdkliqti 257 green anole
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap